Abstract:
STUDY DESIGN:A prospective clinical study in which autologous rib graft, harvested during the thoracotomy in staged scoliosis correction, is stored within the patient for use during the second stage (posterior intrumentation and fusion). OBJECTIVE:To determine whether the bone stored by this technique is biologically viable and microbiologically safe. SUMMARY OF BACKGROUND DATA:To the authors' knowledge, this method of storage of bone has never been described previously. METHODS:During the first operation, the excised rib was divided into 3-5 cm fragments and stored in a sub-muscular plane adjacent to the posterior elements of the spine before closure. The graft was then retrieved at the second stage. Samples were sent for histologic and microbiologic examination before implantation. RESULTS:On histologic examination, more than 50% of the osteocytes retained their basophilic staining, indicating that they were viable. In addition, osteoclastic activity was notably absent. There was no significant bacterial contamination of the samples. Clinically, all patients achieved satisfactory bone fusion. CONCLUSION:Homeostatic equilibrium in humans provides the ideal environment in which bone graft can be stored. There is no increased risk of infection, and the osteogenic potential of the graft is retained.
journal_name
Spine (Phila Pa 1976)journal_title
Spineauthors
Chugh S,Marks DS,Mangham DC,Thompson AGdoi
10.1097/00007632-199808150-00013subject
Has Abstractpub_date
1998-08-15 00:00:00pages
1793-5issue
16eissn
0362-2436issn
1528-1159journal_volume
23pub_type
临床试验,杂志文章相关文献
SPINE文献大全abstract:STUDY DESIGN:Controlled study to assess the efficacy of aprotinin and Amicar in reducing blood loss during complex spinal fusions. OBJECTIVES:To compare blood loss and the clotting profile with a thromboelastogram in patients with spinal deformities undergoing sequential anterior and posterior spinal fusions treated i...
journal_title:Spine
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1097/00007632-200105150-00012
更新日期:2001-05-15 00:00:00
abstract:STUDY DESIGN:A prospective cohort study. OBJECTIVE:The purpose of this study was to compare the surgical outcomes between nonelderly and elderly patients with cervical spondylotic myelopathy (CSM) and to characterize the preoperative symptoms and postoperative residual symptoms in elderly patients. SUMMARY OF BACKGRO...
journal_title:Spine
pub_type: 杂志文章
doi:10.1097/BRS.0000000000002446
更新日期:2018-06-15 00:00:00
abstract:STUDY DESIGN:A rabbit model was used to assess the efficacy of linezolid and vancomycin for the treatment of discitis due to methicillin-resistant Staphylococcus aureus (MRSA). Nontreated controls were used for comparison. OBJECTIVE:The purpose of this study was to determine if there was a therapeutic difference betwe...
journal_title:Spine
pub_type: 杂志文章
doi:10.1097/01.brs.0000241065.19723.13
更新日期:2006-10-15 00:00:00
abstract::This study evaluated the effect of angled insertion of halo pins on the biomechanical characteristics of the halo pin-calvarium complex. Halo pins were inserted into isolated calvarium sections at 90 degrees, 75 degrees, and 60 degrees to the surface of the bone at an insertional torque of 0.68 N-m (6 inch-pounds). In...
journal_title:Spine
pub_type: 杂志文章
doi:10.1097/00007632-198908000-00001
更新日期:1989-08-01 00:00:00
abstract:STUDY DESIGN:Case report. OBJECTIVE:To describe a sudden spinal cord injury in a girl with Prader-Willi syndrome (PWS) 1 week after posterior T2-L3 fusion. SUMMARY OF BACKGROUND DATA:PWS is a genetic disorder characterized by several features including growth deficiency, hypotonia, obesity, and spinal deformities. In...
journal_title:Spine
pub_type: 杂志文章
doi:10.1097/BRS.0b013e318216d357
更新日期:2011-12-15 00:00:00
abstract::Fourteen variations of posterior instrumentation were tested experimentally, using models based on polyester imitation vertebrae, to determine the most effective method for stabilization of a section of the spine following fracture and, in particular, pathologic fracture. The most rigid construction was a well-fitting...
journal_title:Spine
pub_type: 杂志文章
doi:10.1097/00007632-198605000-00014
更新日期:1986-05-01 00:00:00
abstract:STUDY DESIGN:T1rho relaxation was quantified and correlated with intervertebral disc degeneration and proteoglycan content in cadaveric human lumbar spine tissue. OBJECTIVE:To show the use of T1rho-weighted magnetic resonance imaging (MRI) for the assessment of degeneration and proteoglycan content in the human interv...
journal_title:Spine
pub_type: 杂志文章
doi:10.1097/01.brs.0000217708.54880.51
更新日期:2006-05-15 00:00:00
abstract:STUDY DESIGN:For in vitro studies, there is no basis for choosing a "load control study" over a "displacement control" study. This study qualitatively compared results from in vitro and in vivo tests, allowing the authors to address the experimental assumptions that in vitro testing contributes to the understanding of ...
journal_title:Spine
pub_type: 杂志文章
doi:10.1097/00007632-199408000-00015
更新日期:1994-08-01 00:00:00
abstract:STUDY DESIGN:Combined prospective randomized controlled trial and observational cohort study of intervertebral disc herniation (IDH), an as-treated analysis. OBJECTIVE:To determine modifiers of the treatment effect (TE) of surgery (the difference between surgical and nonoperative outcomes) for intervertebral disc hern...
journal_title:Spine
pub_type: 杂志文章,多中心研究,随机对照试验
doi:10.1097/BRS.0b013e3182276b2b
更新日期:2012-01-15 00:00:00
abstract:STUDY DESIGN:Prospective randomized controlled animal model. OBJECTIVE:The purpose of this study is to determine whether the readministration of human recombinant bone morphogenetic protein-2 (rhBMP-2) induces an immune response and inhibits successful fusion in repeat posterolateral spinal surgery. SUMMARY OF BACKGR...
journal_title:Spine
pub_type: 杂志文章,随机对照试验
doi:10.1097/BRS.0b013e3181cdd396
更新日期:2011-02-01 00:00:00
abstract:STUDY DESIGN:A prospective and consecutive study of surgical results obtained during serial follow-up investigations in patients who underwent surgery for central lumbar spinal stenosis. OBJECTIVES:To evaluate the result after surgical decompression for lumbar spinal stenosis, at regular intervals after surgery, and t...
journal_title:Spine
pub_type: 杂志文章
doi:10.1097/00007632-199712150-00017
更新日期:1997-12-15 00:00:00
abstract:STUDY DESIGN:A retrospective, cohort study of the kinematics of the lumbar spine of patients with spondylolisthesis compared with asymptomatic normal subjects. OBJECTIVE:To determine if abnormal motion could be detected in the radiographs of patients with spondylolisthesis. SUMMARY OF BACKGROUND DATA:Contrary to the ...
journal_title:Spine
pub_type: 杂志文章
doi:10.1097/01.brs.0000162400.06685.37
更新日期:2005-05-15 00:00:00
abstract:STUDY DESIGN:Retrospective Analysis OBJECTIVE.: The aim of this study was to determine whether an association between increased acute pain, postoperative time, and direct hospital costs exists between the use of iliac crest bone grafting (ICBG) and bone morphogenic protein (BMP)-2 following a primary, single-level mini...
journal_title:Spine
pub_type: 杂志文章
doi:10.1097/BRS.0000000000002599
更新日期:2018-09-15 00:00:00
abstract:STUDY DESIGN:A population-based, prospective cohort study. OBJECTIVE:To identify demographic, job-related, psychosocial, and clinical factors associated with the use of magnetic resonance imaging (MRI) within 6 weeks from injury (early MRI) among workers' compensation claimants with acute occupational low back pain (L...
journal_title:Spine
pub_type: 杂志文章
doi:10.1097/BRS.0b013e31823a03cc
更新日期:2012-09-01 00:00:00
abstract:STUDY DESIGN:Retrospective. OBJECTIVES:To document sagittal translation (ST) of the vertebral column in opening wedge osteotomy (OWO) for ankylosing spondylitis (AS) kyphosis. SUMMARY OF BACKGROUND DATA:Surgeons recognize displacement at the hinge of correction in OWO as an accidental event between the vertebrae on t...
journal_title:Spine
pub_type: 杂志文章
doi:10.1097/01.brs.0000216479.09250.96
更新日期:2006-05-01 00:00:00
abstract:STUDY DESIGN:In vivo validation during functional loading. OBJECTIVE:To determine the accuracy and repeatability of a model-based tracking technique that combines subject-specific computed tomographic (CT) models and high-speed biplane x-ray images to measure three-dimensional (3D) in vivo cervical spine motion. SUMM...
journal_title:Spine
pub_type: 杂志文章
doi:10.1097/BRS.0b013e31820b7e2f
更新日期:2011-03-15 00:00:00
abstract:STUDY DESIGN:Validity and responsiveness study using a randomized clinical trial and prospective cohort study of patients with low back pain (LBP). OBJECTIVE:To provide evidence for construct validity and responsiveness to change of a single-item presenteeism question (SIPQ) in patients with LBP. SUMMARY OF BACKGROUN...
journal_title:Spine
pub_type: 杂志文章
doi:10.1097/BRS.0000000000000162
更新日期:2014-03-01 00:00:00
abstract:STUDY DESIGN:Cost-effectiveness analysis. OBJECTIVE:To examine the cost-effectiveness of operative versus non-operative treatment of type-II odontoid fractures in patients older than 64 years old. SUMMARY OF BACKGROUND DATA:Significant controversy exists regarding the optimum treatment of geriatric patients with type...
journal_title:Spine
pub_type: 杂志文章
doi:10.1097/BRS.0000000000001275
更新日期:2016-04-01 00:00:00
abstract:STUDY DESIGN:Retrospective review of long-term outcome of fusion in situ for congenital vertebral anomaly with particular emphasis on cosmesis and the incidence of reoperation. OBJECTIVE:Examination of the success rate of this procedure and of risk factors for failure. BACKGROUND:Fusion in situ is the accepted prophy...
journal_title:Spine
pub_type: 杂志文章
doi:10.1097/00007632-200203150-00011
更新日期:2002-03-15 00:00:00
abstract:STUDY DESIGN:A case report of traumatic atlantooccipital dislocation (AOD) managed by intraarticular-posterior fusion from a posterior approach at the C0-C1 level with preservation of C1-C2 motion. OBJECTIVE:To present a new technique for atlantooccipital fusion with long-term follow-up. SUMMARY OF BACKGROUND DATA:Th...
journal_title:Spine
pub_type: 杂志文章
doi:10.1097/BRS.0b013e3181c91fa1
更新日期:2010-05-01 00:00:00
abstract:STUDY DESIGN:In vitro assessment of the effects of platelet-rich plasma on the extracellular matrix metabolism of porcine intervertebral disc cells. OBJECTIVES:To determine whether platelet-rich plasma is effective in stimulating cell proliferation and extracellular matrix metabolism by porcine disc cells cultured in ...
journal_title:Spine
pub_type: 杂志文章
doi:10.1097/01.brs.0000214942.78119.24
更新日期:2006-04-20 00:00:00
abstract:STUDY DESIGN:Experimental animal study. OBJECTIVES:This study evaluates the in vitro and in vivo transduction efficacy and transgene expression in immune competent and pre-exposed rabbits. SUMMARY OF BACKGROUND DATA:Degenerative disc disease (DDD) continues to pose a substantial clinical problem. Therapeutic options ...
journal_title:Spine
pub_type: 杂志文章
doi:10.1097/01.brs.0000154764.62072.44
更新日期:2005-03-01 00:00:00
abstract:STUDY DESIGN:Cross-sectional cohort study of chronic low back pain (CLBP) patients and matched controls. OBJECTIVE:To explore the interplay between vertebral endplate damage and adjacent paraspinal muscle (PSM) quality, and to test their association in a cohort of patients with CLBP and matched controls. SUMMARY OF B...
journal_title:Spine
pub_type: 杂志文章
doi:10.1097/BRS.0000000000003035
更新日期:2019-07-15 00:00:00
abstract:STUDY DESIGN:Carotid artery blood flow was measured in 15 patients undergoing anterior cervical spine surgery. OBJECTIVE:To determine the effect of intraoperative retraction on carotid artery flow dynamics. SUMMARY OF BACKGROUND DATA:Adequate surgical exposure for anterior cervical discectomy and fusion necessitates ...
journal_title:Spine
pub_type: 杂志文章
doi:10.1097/00007632-200201150-00006
更新日期:2002-01-15 00:00:00
abstract:STUDY DESIGN:Clinical trial (phase II). OBJECTIVES:To assess the feasibility and safety of balloon vertebroplasty after posterior short-segment reduction and fixation for the treatment of traumatic burst fractures. SUMMARY OF BACKGROUND DATA:Hardware failure and loss of reduction after posterior short-segment instrum...
journal_title:Spine
pub_type: 杂志文章
doi:10.1097/01.brs.0000152162.64015.fb
更新日期:2005-02-01 00:00:00
abstract:STUDY DESIGN:Retrospective study. OBJECTIVE:To evaluate the incidence of fusion failure after anterior screw fixation of type II and rostral shallow type III fractures and to identify related risk factors. SUMMARY OF BACKGROUND DATA:Although several studies have reported fusion rates after anterior odontoid screw fix...
journal_title:Spine
pub_type: 杂志文章
doi:10.1097/BRS.0b013e31820e6418
更新日期:2012-01-01 00:00:00
abstract:STUDY DESIGN:We measured the cross-sectional area of the intervertebral discs of normal volunteers after an overnight rest; before, during, and after 5 or 17 weeks of bed rest; and before and after 8 days of weightlessness. OBJECTIVES:This study sought to determine the degree of expansion of the lumbar discs resulting...
journal_title:Spine
pub_type: 杂志文章
doi:10.1097/00007632-199404000-00015
更新日期:1994-04-01 00:00:00
abstract:STUDY DESIGN:Retrospective review of a prospectively collected, multicentered database from the Scoliosis Research Society. OBJECTIVES:To evaluate incidences of complications in a series of spinal fusions for Scheuermann kyphosis (SK) and to assess whether the incidence of complications is associated with patient age ...
journal_title:Spine
pub_type: 杂志文章,多中心研究
doi:10.1097/BRS.0b013e3181c47f0f
更新日期:2010-01-01 00:00:00
abstract:STUDY DESIGN:Prospective study on intraoperative blood loss during lumbar spine surgery. OBJECTIVE:To evaluate the relationship between airway pressure change due to the patient's prone position and intraoperative blood loss during lumbar spine surgery. SUMMARY OF BACKGROUND DATA:A prone position may increase abdomin...
journal_title:Spine
pub_type: 临床试验,杂志文章
doi:10.1097/BRS.0b013e31828cb3e5
更新日期:2013-05-15 00:00:00
abstract:STUDY DESIGN:Independent retrospective review of prospectively collected data, comparative cohort study. OBJECTIVE:The objective of this study was to compare the clinical, radiographical, and cost/value of the addition of an interbody arthrodesis (IBA) to a posterolateral arthrodesis (PLA) in the surgical treatment of...
journal_title:Spine
pub_type: 杂志文章
doi:10.1097/BRS.0000000000000856
更新日期:2015-06-15 00:00:00