The adeno associated viral vector as a strategy for intradiscal gene transfer in immune competent and pre-exposed rabbits.

abstract：STUDY DESIGN:The segmental levels of dorsal root ganglions innervating the sacroiliac joint in rats were investigated using the retrograde transport method. The pathways and functions of the nerve fibers supplying the sacroiliac joint were determined by immunohistochemical detection of transported tracer. OBJECTIVES:T...

journal_title：Spine

authors： Murata Y,Takahashi K,Yamagata M,Takahashi Y,Shimada Y,Moriya H

更新日期：2000-08-15 00:00:00

abstract：:Prior irradiation and scarring can complicate wound closure following spinal surgery. Implanted tissue expanders were used six times in four patients to aid skin closure. Three patients had prior irradiation for cancer, and one had myelomeningocele. The average interval between placement and removal of the expanders w...

journal_title：Spine

authors： Paonessa KJ,Zide B,Errico T,Engler GL

更新日期：1991-08-01 00:00:00

abstract：:An analysis of indications, techniques, results of stabilization and decompression of 100 consecutive spinal tumour cases was carried out. Localized metastatic disease is best operated anteriorly. Primary malignancies are best treated with en bloc resection. Pain relief in metastatic disease is achieved by rigid stabi...

journal_title：Spine

authors： Kostuik JP,Errico TJ,Gleason TF,Errico CC

更新日期：1988-03-01 00:00:00

abstract：STUDY DESIGN:Comparative 3-dimensional biomechanical testing. OBJECTIVE:To compare 5 fixation techniques, 3 using screws or screw and plates and 2 spinal, used for stabilization of complete unilateral sacroiliac dislocation in composite models. SUMMARY OF BACKGROUND DATA:Harrington compression rods have been used for...

journal_title：Spine

authors： Korovessis PG,Magnissalis EA,Deligianni D

更新日期：2006-12-01 00:00:00

abstract：STUDY DESIGN:The authors retrospectively reviewed 28 patients with multilevel Pott disease who underwent anterior radical débridement, decompression, and fusion with anterior spinal instrumentation and fibular allograft replacement. OBJECTIVES:To assess the efficacy of allograft fibular fusion and anterior spinal stab...

journal_title：Spine

authors： Ozdemir HM,Us AK,Oğün T

更新日期：2003-03-01 00:00:00

abstract：STUDY DESIGN:The strength of posterior cervical lateral mass fixation was evaluated in a cadaver model for two techniques of screw insertion. OBJECTIVE:To compare the flexion failure strengths of posterior cervical plate fixation for two techniques of screw placement at the superior and inferior screw hole positions, ...

journal_title：Spine

authors： Choueka J,Spivak JM,Kummer FJ,Steger T

更新日期：1996-02-15 00:00:00

abstract：:The influences of age, sex, disc level, and degree of degenration on the mechanical behavior of 42 fresh cadaver lumbar motion segments are reported. The motions and intradiscal pressure changes that result from the application of flexion, extension, lateral bending, and torsional moments; compression; and anterior, p...

journal_title：Spine

authors： Nachemson AL,Schultz AB,Berkson MH

更新日期：1979-01-01 00:00:00

abstract：STUDY DESIGN:This case report shows primary natural killer (NK)/T-cell lymphoma originating in the spine as the first case of successful treatment with autologous stem cell transplantation, along with case presentation and literature review. OBJECTIVE:For the proper treatment of this spinal tumor, the pathologic confi...

journal_title：Spine

authors： Kim KT,Kim YB,Kim HJ,Cha YJ,Lee SJ,Park E

更新日期：2012-05-01 00:00:00

abstract：STUDY DESIGN:Retrospective cohort analysis of prospectively collected clinical data. OBJECTIVE:To compare outcomes of elective spine fusion and laminectomy when performed by neurological and orthopedic surgeons. SUMMARY OF BACKGROUND DATA:The relationship between primary specialty training and outcome of spinal surge...

journal_title：Spine

authors： Seicean A,Alan N,Seicean S,Neuhauser D,Benzel EC,Weil RJ

更新日期：2014-09-01 00:00:00

abstract：:It is hypothesized on the basis of experimental intervertebral disc degeneration that herniated disc is actually newly synthesized proliferative metaplastic fibrocartilage and not herniation of pre-existing disc tissue, particularly that of the nucleus pulposus. Human material in selected surgical tissues was examined...

journal_title：Spine

authors： Lipson SJ

更新日期：1988-09-01 00:00:00

abstract：STUDY DESIGN:A case of iatrogenic intramedullary contrast injection during a C1-C2 cervical myelography is reported. OBJECTIVE:To investigate the occurrence of iatrogenic intramedullary contrast injection during a current C1-C2 cervical myelography. SUMMARY OF BACKGROUND DATA:Intramedullary injection of contrast is a...

journal_title：Spine

authors： Simon SL,Abrahams JM,Sean Grady M,LeRoux PD,Rushton SA

更新日期：2002-05-15 00:00:00

abstract：STUDY DESIGN:Twenty-seven patients underwent instrumented transforaminal lumbar interbody fusion (TLIF) procedures using bioresorbable implants as interbody spacers. The greater than 2-year clinical and radiographic results of this series are presented along with as a review of relevant preclinical and preliminary clin...

journal_title：Spine

authors： Coe JD,Vaccaro AR

更新日期：2005-09-01 00:00:00

abstract：:Double level compression of nerve roots has been known to exist for a long time, but only in recent years the clinical significance of such conditions has been discussed. In the current study, nerve root function in double level compression was analyzed by measurements of tail muscle electromyogram, after stimulations...

journal_title：Spine

authors： Matsui H,Olmarker K,Cornefjord M,Takahashi K,Rydevik B

更新日期：1992-09-01 00:00:00

abstract：:The purpose of this study was to assess the natural history of sciatica due to lumbosacral nerve root compromise and to evaluate the pathomorphologic changes that accompany the natural resolution of the disease. One hundred sixty-five consecutive patients, 114 males and 51 females, with an average age of 41 years (ran...

journal_title：Spine

authors： Bush K,Cowan N,Katz DE,Gishen P

更新日期：1992-10-01 00:00:00

abstract：STUDY DESIGN:Observational. OBJECTIVE:To estimate the radiation dose imparted to patients during typical thoracolumbar spinal surgical scenarios. SUMMARY OF BACKGROUND DATA:Minimally invasive techniques continue to become more common in spine surgery. Computer-assisted navigation systems coupled with intraoperative c...

journal_title：Spine

authors： Lange J,Karellas A,Street J,Eck JC,Lapinsky A,Connolly PJ,Dipaola CP

更新日期：2013-03-01 00:00:00

abstract：:The study is an investigation into the form of the abdominal pressure reflex in normal individuals under isometric loading of the torso. Various directions of load are imposed, and both flexed and upright postures are adopted. The sensitivity of the pressurization to the applied moment is calculated, the form of the r...

journal_title：Spine

authors： Grew ND

更新日期：1980-03-01 00:00:00

abstract：STUDY DESIGN:This study was an exploratory repeated measures design comparing patients undergoing two magnitudes of surgery in the lumbar spine: lumbar herniated disc repair and posterior lumbar fusion. OBJECTIVE:The present study evaluated and compared the effect of perceived pain, perceived stress, anxiety, and mood...

journal_title：Spine

authors： Starkweather AR,Witek-Janusek L,Nockels RP,Peterson J,Mathews HL

更新日期：2006-08-15 00:00:00

abstract：:This is a brief review of the life and contributions to neurologic science of Sir William Gowers. He was a neurologist in England in the late 19th century who, before the availability of modern diagnostic aids, established the importance of clinical examination, including history and physical signs, in the diagnosis o...

journal_title：Spine

authors： Mulholland RC

更新日期：1996-05-01 00:00:00

abstract：STUDY DESIGN:A prospective double-blind randomized controlled trial was performed. OBJECTIVE:To assess the efficacy of percutaneous radiofrequency articular facet denervation for low back pain. SUMMARY OF BACKGROUND DATA:Uncontrolled observational studies in patients with low back pain have reported some benefits fro...

journal_title：Spine

authors： Leclaire R,Fortin L,Lambert R,Bergeron YM,Rossignol M

更新日期：2001-07-01 00:00:00

abstract：:A clinical trial, aimed at secondary prevention of low-back pain, was performed in 142 hospital employees reporting at least three annual episodes of this condition. Participants were randomly assigned to one of three groups: a calisthenics program (CAL) for 3 months with biweekly sessions of flexion exercises, a back...

journal_title：Spine

authors： Donchin M,Woolf O,Kaplan L,Floman Y

更新日期：1990-12-01 00:00:00

abstract：STUDY DESIGN:Systematic Review and Meta-Analysis OBJECTIVE.: To identify whether intramuscular local anesthetic infiltration prior to wound closure was effective in reducing postoperative pain and facilitating early discharge following lumbar spine surgery. SUMMARY OF BACKGROUND DATA:Local anesthetic infiltration prio...

journal_title：Spine

authors： Perera AP,Chari A,Kostusiak M,Khan AA,Luoma AM,Casey ATH

更新日期：2017-07-15 00:00:00

abstract：STUDY DESIGN:Case report. OBJECTIVE:To describe a patient with ischemic orbital compartment syndrome after undergoing spinal surgery in a prone position. SUMMARY OF BACKGROUND DATA:Ocular complications after nonocular surgery are devastating. The most common etiology is ischemic optic neuropathy. Orbital compartment ...

journal_title：Spine

authors： Yu YH,Chen WJ,Chen LH,Chen WC

更新日期：2008-07-15 00:00:00

abstract：STUDY DESIGN:Animal experimental study. OBJECTIVE:The aim of this study was to investigate the optimal time of hydrogel injection for regenerating intervertebral disc degeneration (IDD) based on T1ρ magnetic resonance imaging (MRI). SUMMARY OF BACKGROUND DATA:Currently, different approaches are being pursued to regen...

journal_title：Spine

authors： Liu Z,Li J,Hu M,Wang X,Chen N,Cui S,Li S,Liu H,Chen G,Pan X,Sun H,Liu S,Wei F

更新日期：2020-11-15 00:00:00

abstract：STUDY DESIGN:This study developed and independently applied a spine tumor classification system, referred to as the Weinstein-Boriani-Biagini system, in a retrospective analysis of a series of patients with spinal giant cell tumors from three institutions. OBJECTIVE:To evaluate factors of potential prognostic signific...

journal_title：Spine

authors： Hart RA,Boriani S,Biagini R,Currier B,Weinstein JN

更新日期：1997-08-01 00:00:00

abstract：STUDY DESIGN:Case report. OBJECTIVE:To report a case of an acute intracranial subdural hematoma that formed due to cerebrospinal fluid (CSF) leak following lumbar surgery. SUMMARY OF BACKGROUND DATA:Intracranial hypotension may occur when CSF is removed from the subarachnoid space. Intracranial subdural hematoma form...

journal_title：Spine

authors： Sciubba DM,Kretzer RM,Wang PP

更新日期：2005-12-15 00:00:00

abstract：STUDY DESIGN:A retrospective review of 10 consecutive patients with a noninflammatory retro-odontoid pseudotumor. OBJECTIVE:To examine the radiographic characteristics in patients with a retro-odontoid pseudotumor and to evaluate the efficacy of posterior fusion. SUMMARY OF BACKGROUND DATA:A retro-odontoid pseudotumo...

journal_title：Spine

authors： Chikuda H,Seichi A,Takeshita K,Shoda N,Ono T,Matsudaira K,Kawaguchi H,Nakamura K

更新日期：2009-02-01 00:00:00

abstract：STUDY DESIGN:This cohort study compares motion characteristics during forward bending of a group of chronic female patients either with low back pain (LBP) or pelvic girdle pain (PGP) and healthy subjects using computer-video analysis. OBJECTIVE:This study determines whether subcategories of back pain patients could b...

journal_title：Spine

authors： van Wingerden JP,Vleeming A,Ronchetti I

更新日期：2008-05-15 00:00:00

abstract：STUDY DESIGN:A prospective follow-up study. OBJECTIVE:Assessment of the relation between accomplishment of pain relief through percutaneous vertebroplasty (PVP) in painful osteoporotic vertebral compression fractures (OVCFs) and the cemented fraction of the vertebral body and subsequent determination of the optimal in...

journal_title：Spine

authors： Nieuwenhuijse MJ,Bollen L,van Erkel AR,Dijkstra PD

更新日期：2012-09-15 00:00:00

abstract：STUDY DESIGN:Posture and motion analysis after a Cotrel-Dubousset instrumentation. OBJECTIVES:To investigate the compensation role of pelvis. SUMMARY OF BACKGROUND DATA:Few existing studies found no compensation at the lower unfused level but did not investigate the pelvis. METHODS:Thirty patients were analyzed befo...

journal_title：Spine

authors： Skalli W,Zeller RD,Miladi L,Bourcereau G,Savidan M,Lavaste F,Dubousset J

更新日期：2006-05-20 00:00:00

abstract：STUDY DESIGN:A morphometric analysis, using magnetic resonance imaging (MRI) studies of the lumbar spine. OBJECTIVE:To identify the anatomic position of the ventral root and the retroperitoneal vessels in relation to the vertebral body in normally aligned and deformed spines. SUMMARY OF BACKGROUND DATA:The lateral ap...

journal_title：Spine

authors： Regev GJ,Chen L,Dhawan M,Lee YP,Garfin SR,Kim CW

更新日期：2009-05-20 00:00:00