Intradermal testing after severe histamine reactions to intravenous drugs used in anaesthesia.

Abstract:

:In a series of patients who suffered severe histamine mediated reactions to induction agents and muscle relaxants, intradermal testing enabled the drug involved to be distinguished. The correct use of intradermal testing to give reliable results is discussed and a protocol described. Prausnitz Kustner testing was of little help in confirming the results. A number of patients tested showed high levels of immunoglobulin G (IgG) and it is believed that IgG mediated anaphylaxis may be the mechanism responsible for reactions that have been previously described as anaphylactoid or direct chemical histamine release.

journal_name

Anaesth Intensive Care

authors

Fisher MM

doi

10.1177/0310057X7600400202

subject

Has Abstract

pub_date

1976-05-01 00:00:00

pages

97-104

issue

2

eissn

0310-057X

issn

1448-0271

journal_volume

4

pub_type

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