Course of vasopressin and copeptin plasma concentrations in a patient with severe septic shock.

Abstract:

:In this case report, the course of arginine vasopressin and copeptin, the stable C-terminal part of the arginine vasopressin precursor, is described during the period of critical illness in a septic shock patient. Arginine vasopressin and copeptin concentrations were substantially increased during the initial 36 hours of shock. Subsequently, both hormones continuously decreased, but exhibited another peak in response to stress during extubation. During restoration of cardiovascular stability, endogenous arginine vasopressin levels further decreased and obviously did not contribute to haemodynamic improvement. In contrast, the decrease in arginine vasopressin and copeptin can be at least partly explained by an improvement of cardiovascular function.

journal_name

Anaesth Intensive Care

authors

Jochberger S,Luckner G,Mayr VD,Wenzel V,Morgenthaler NG,Friesenecker BE,Hasibeder WR,Dünser MW

doi

10.1177/0310057X0603400415

subject

Has Abstract

pub_date

2006-08-01 00:00:00

pages

498-500

issue

4

eissn

0310-057X

issn

1448-0271

pii

2006068

journal_volume

34

pub_type

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