Spinal pain mechanisms.

Abstract:

:Pain is an extremely complex process that involves the interaction of an array of neurotransmitters and neuromodulators at all levels of the neuraxis. Identification of the receptors and processes that are involved in the transmission of pain at a spinal level has led to the use of new agents and new techniques in pain management. These include use of preemptive analgesia and use of techniques such as intrathecal drug administration and epidural spinal cord stimulation. This review presents some of the findings from basic research that have led to these developments, particularly those that relate to the changes that occur following inflammation and nerve injury.

journal_name

Spine (Phila Pa 1976)

journal_title

Spine

authors

Siddall PJ,Cousins MJ

doi

10.1097/00007632-199701010-00016

subject

Has Abstract

pub_date

1997-01-01 00:00:00

pages

98-104

issue

1

eissn

0362-2436

issn

1528-1159

journal_volume

22

pub_type

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