Abstract:
:Diffuse pontine tumors are highly lethal and conventional therapy with irradiation provides long-term survival to a very small proportion of the patients. We have reported promising results using high-dose chemotherapy with autologous stem cell rescue in patients with recurrent high-grade astrocytomas in other anatomic locations, but our results and those of others have been very discouraging in children with brain stem tumors. Alternative strategies need to be developed for this highly lethal disease.
journal_name
Pediatr Neurosurgjournal_title
Pediatric neurosurgeryauthors
Dunkel IJ,O'Malley B,Finlay JLdoi
10.1159/000121049subject
Has Abstractpub_date
1996-01-01 00:00:00pages
263-6issue
5eissn
1016-2291issn
1423-0305journal_volume
24pub_type
杂志文章abstract::Malignant tumors arising within dysrhaphic malformations are very rare and are mostly teratomas; so far, only one rhabdomyosarcoma has been reported in this context. We report another case of a girl with lipomyelomeningocele who developed a lumbar rhabdomyosarcoma 2 years after birth and primary closure of the neural ...
journal_title:Pediatric neurosurgery
pub_type: 杂志文章,评审
doi:10.1159/000083742
更新日期:2004-11-01 00:00:00
abstract:BACKGROUND:Growing skull fracture (GSF)/pseudomeningocele is a rare complication of head injury in children. Post-traumatic intradiploic arachnoid cyst (PTIAC) is a variant but it is extremely rare. PTIACs are usually asymptomatic or with mild symptoms like headache. The rupture of PTIAC due to re-trauma leading to pse...
journal_title:Pediatric neurosurgery
pub_type: 杂志文章
doi:10.1159/000369936
更新日期:2015-01-01 00:00:00
abstract::A young patient with a large left hemisphere porencephalic cyst underwent neuroimaging investigation (functional magnetic resonance imaging (fMRI), EEG-fMRI, DTI tractography) during presurgical evaluation for intractable epilepsy. The functional workup showed that (a) the healthy hemisphere had undertaken language pr...
journal_title:Pediatric neurosurgery
pub_type: 杂志文章
doi:10.1159/000330546
更新日期:2011-01-01 00:00:00
abstract::Six patients with hydrocephalus who were treated with cerebrospinal fluid (CSF) shunts became refractory to serosal absorption of CSF. All were subsequently treated with ventriculo-gallbladder shunts. The surgical technique and long-term results were evaluated by retrospective review of the hospital records. Detailed ...
journal_title:Pediatric neurosurgery
pub_type: 杂志文章
doi:10.1159/000121191
更新日期:1997-04-01 00:00:00
abstract::A needle for intravenous fluid administration in a newborn was accidentally placed in the sagittal sinus and resulted in dural sinus air embolism. CT findings are described and the risks for venous air embolism are discussed. ...
journal_title:Pediatric neurosurgery
pub_type: 杂志文章
doi:10.1159/000120606
更新日期:1991-01-01 00:00:00
abstract::Kernohan-Woltman notch phenomenon (KWNP) is an ipsilateral motor weakness due to compression of the contralateral cerebral peduncle. Most of the KWNP cases reported have been due to subdural hematomas, intracranial space-occupying lesions, and spontaneous bleeding of vascular malformations. In this study, we present t...
journal_title:Pediatric neurosurgery
pub_type: 杂志文章
doi:10.1159/000474945
更新日期:2017-01-01 00:00:00
abstract::Intracranial schwannomas not arising from a cranial nerve are very rare. Schwannomas of the dura are even rarer; in the literature, we found only two cases: a schwannoma of the falx and one of the torcula. We report a third case of a 9-year-old girl with a schwannoma of the tentorium cerebelli. The different theories ...
journal_title:Pediatric neurosurgery
pub_type: 杂志文章
doi:10.1159/000048371
更新日期:2002-03-01 00:00:00
abstract::Central pontine myelinolysis occurs inconsistently as a complication of severe and prolonged hyponatremia, particularly when corrected too rapidly. It is a concentrated, frequently symmetric, noninflammatory demyelination within the central basis pontis. We describe a head injury patient who suffered this clinical ent...
journal_title:Pediatric neurosurgery
pub_type: 杂志文章
doi:10.1159/000315003
更新日期:2010-01-01 00:00:00
abstract::A case of an intracerebral juvenile xanthogranuloma (JXG) producing complex-partial seizures in a 13-year-old boy is presented. Although the child had no history of JXGs or a systemic histiocytic proliferative disorder, the histopathological and immunocytochemical studies of this lesion were identical to that of a cut...
journal_title:Pediatric neurosurgery
pub_type: 杂志文章,评审
doi:10.1159/000121212
更新日期:1997-06-01 00:00:00
abstract::The unified theory, proposed by Pang et al., explains the embryogenetic mechanisms of all variants of split cord malformations (SCMs). All SCMs originate from one basic error occurring around the time when the primitive neurenteric canal closes. The basic error is the formation of an accessory neurenteric canal betwee...
journal_title:Pediatric neurosurgery
pub_type: 杂志文章
doi:10.1159/000121033
更新日期:1996-01-01 00:00:00
abstract::We here describe the case of a boy with an atypical teratoid-rhabdoid tumor (ATRT) of the 4th ventricle at 1 year of age and a local tumor recurrence at 19 months of age. Due to brainstem infiltration, only incomplete tumor resection was possible each time. High-dose chemotherapy, stem cell transplantation and irradia...
journal_title:Pediatric neurosurgery
pub_type: 杂志文章
doi:10.1159/000092366
更新日期:2006-01-01 00:00:00
abstract::Arachnoid cysts (ACs) are relatively common intracranial mass lesions, which occur most often in the middle cranial fossa. While these lesions can present as a mass lesion, many are asymptomatic. Rarely, posttraumatic or spontaneous rupture of ACs can result in intracystic hemorrhage, subdural hematoma or subdural hyg...
journal_title:Pediatric neurosurgery
pub_type: 杂志文章
doi:10.1159/000028918
更新日期:2000-03-01 00:00:00
abstract::A retrospective study of fractures of peritoneal catheters of ventriculoperitoneal shunts is described. Fracture of the peritoneal catheter accounts for 21.2% of shunt revisions. During the time period of January 1985 through July 1993, 401 PS Medical peritoneal catheters were installed and 23 fractures occurred. The ...
journal_title:Pediatric neurosurgery
pub_type: 杂志文章
doi:10.1159/000120884
更新日期:1995-01-01 00:00:00
abstract:OBJECTIVE:Modern neuroimaging and intensive care permit precise delineation and specific treatment of head injury. Children sustaining cranial trauma associated with epidural hematoma (EDH) represent a heterogeneous group with a variety of clinical outcomes. Treatment consists of simple observation or surgical evacuati...
journal_title:Pediatric neurosurgery
pub_type: 杂志文章
doi:10.1159/000121144
更新日期:1996-12-01 00:00:00
abstract::We describe the initiation and development of a comprehensive multidisciplinary and multi-institutional program for the evaluation and management of youth with spasticity. A descriptive step-by-step process of the administrative and organizational sequence of the development of the program is delineated. The Spasticit...
journal_title:Pediatric neurosurgery
pub_type: 杂志文章,多中心研究
doi:10.1159/000355125
更新日期:2013-01-01 00:00:00
abstract::Several groups have begun to explore the feasibility and utility of intrauterine closure of myelomeningocele. A subset of these fetuses have defects which fall into the category of myeloschisis, and therefore have inadequate skin to enable primary closure. After considerable discussion, it was decided to utilize biped...
journal_title:Pediatric neurosurgery
pub_type: 杂志文章
doi:10.1159/000028898
更新日期:2000-01-01 00:00:00
abstract:OBJECTIVE:Tumours of the choroid plexus are rare tumours of neuro-ectodermal origin, accounting for less than 1% of all intracranial tumours. Most cases present in children less than 2 years of age. While choroid plexus carcinomas (CPC) are reported to have an extremely poor prognosis, choroid plexus papillomas (CPP) a...
journal_title:Pediatric neurosurgery
pub_type: 杂志文章
doi:10.1159/000028933
更新日期:2000-04-01 00:00:00
abstract:BACKGROUND:Initial therapy for craniopharyngioma remains controversial. Population-based datasets indicate that traditional algorithms [gross total resection (GTR) vs. subtotal resection (STR) +/- radiation therapy (XRT)] are often not employed. We investigated neurosurgical practice patterns. METHODS:A ten-question s...
journal_title:Pediatric neurosurgery
pub_type: 杂志文章
doi:10.1159/000357783
更新日期:2013-01-01 00:00:00
abstract::Tumors located in the region of the foramen of Monro often present with signs and symptoms of obstructive hydrocephalus. Various types of lesions occur in this location. We describe a case of a dysembryoplastic neuroepithelial tumor of the septum pellucidum presenting with obstructive hydrocephalus and its successful ...
journal_title:Pediatric neurosurgery
pub_type: 杂志文章
doi:10.1159/000090464
更新日期:2006-01-01 00:00:00
abstract::A 3-month-old female patient presented with a meningomyelocele at the lumber region associated with congenital hydrocephalus. She underwent ventriculoperitoneal (V-P) shunt surgery using the Sophy system. The shunt system was replaced due to a malformation. Following replacement, the patient presented with cerebrospin...
journal_title:Pediatric neurosurgery
pub_type: 杂志文章
doi:10.1159/000028752
更新日期:1999-01-01 00:00:00
abstract:BACKGROUND:Midline suboccipital craniotomy has been proposed as an alternative to conventional craniectomy for removal of posterior fossa tumors. METHOD:We describe a modified technique for midline suboccipital osteoplastic craniotomy based on the atlantooccipital membrane for a 17-year-old boy with superior vermian a...
journal_title:Pediatric neurosurgery
pub_type: 杂志文章
doi:10.1159/000354220
更新日期:2012-01-01 00:00:00
abstract::Hepatic pseudocyst formation is a rare intra-abdominal complication of ventriculoperitoneal shunts. The presence of an intracranial tumor and a history of central nervous system infection are major risk factors for the development of this complication. Hepatic pseudocysts secondary to ventriculoperitoneal shunts can b...
journal_title:Pediatric neurosurgery
pub_type: 杂志文章,评审
doi:10.1159/000108795
更新日期:2007-01-01 00:00:00
abstract::We report here the first case of ruptured arteriovenous malformation (AVM) in a patient with Beckwith-Wiedemann syndrome (BWS). The subject was a 9-year-old boy exhibiting various abnormal features characteristic of BWS, who had undergone frequent surgical management for conditions such as umbilical hernia, polydactyl...
journal_title:Pediatric neurosurgery
pub_type: 杂志文章
doi:10.1159/000028854
更新日期:1999-09-01 00:00:00
abstract::Atlantoaxial rotatory subluxation (AARS) is an uncommon disease with a greater prevalence in children than adults. So far there has only been one report of AARS after surgery related to ventriculoperitoneal (VP) shunting. We present a new case of AARS closed reduction treatment after VP shunt removal in an 8-year-old ...
journal_title:Pediatric neurosurgery
pub_type: 杂志文章
doi:10.1159/000433601
更新日期:2015-01-01 00:00:00
abstract::Stereotactic radiosurgery has had an increasing role in the treatment of selected intracranial lesions in pediatric patients. In our first 44 months experience, 60 of the patients (9%) treated were less than or equal to 18 years of age. Current indications for radiosurgery include primary treatment of high-risk arteri...
journal_title:Pediatric neurosurgery
pub_type: 杂志文章
doi:10.1159/000120530
更新日期:1990-01-01 00:00:00
abstract:INTRODUCTION:Our appreciation and understanding of what is now known as the split cord malformation (SCM) have a long history. The oldest known example of SCM is from roughly AD 100. Other isolated examples can be found in the large body of work of the pathologists of the 1800s, where the SCMs were found incidentally d...
journal_title:Pediatric neurosurgery
pub_type: 历史文章,杂志文章
doi:10.1159/000450584
更新日期:2017-01-01 00:00:00
abstract::A case is presented illustrating the usefulness of computerized tomography (CT) with 3-dimensional (3-D) reconstruction for evaluation of a subdental synchondrosis fracture in a child. Odontoid fractures in children less than 7 years of age occur at the subdental synchondrosis and are typically diagnosed with plain x-...
journal_title:Pediatric neurosurgery
pub_type: 杂志文章
doi:10.1159/000121135
更新日期:1996-11-01 00:00:00
abstract::Posterior plagiocephaly secondary to lambdoid suture stenosis requires surgical release and repair to prevent progressive deformational changes associated with a suture stenosis. A surgical technique is described for release of the stenosed lambdoid suture and asterion region, followed by occipital reconstruction. Thi...
journal_title:Pediatric neurosurgery
pub_type: 杂志文章
doi:10.1159/000120895
更新日期:1995-01-01 00:00:00
abstract::Ten children with a tethered cord and also an anorectal malformation are reported in this document. The anorectal malformations comprised 5 vesicointestinal fissures, 2 cloacal exstrophies, 2 rectovesical fistulas and 1 rectobulbar fistula. All of the patients underwent colostomy in advance of surgery for untethering ...
journal_title:Pediatric neurosurgery
pub_type: 杂志文章
doi:10.1159/000068048
更新日期:2003-02-01 00:00:00
abstract::Thirty-six cases of pilocytic astrocytomas treated at the Childrens Hospital of Los Angeles from 1984 through 1995 were reviewed. The mean age at initial presentation was 8 years (range 15 months to 14 years). These patients were followed for an average of 5.5 years. No patient was given chemotherapy or radiation ther...
journal_title:Pediatric neurosurgery
pub_type: 杂志文章,评审
doi:10.1159/000121218
更新日期:1997-07-01 00:00:00