Evaluation of trauma care: validation of the TRISS method in an Italian ICU.

abstract：PURPOSE:To assess the generalisability of published clinical risk predictive models for invasive candidiasis in ICU patients. METHODS:The performance characteristics of published clinical risk factor-only and Candida colonisation-only predictive models for invasive candidiasis were assessed in a multicentre cohort of ...

journal_title：Intensive care medicine

authors： Playford EG,Lipman J,Kabir M,McBryde ES,Nimmo GR,Lau A,Sorrell TC

更新日期：2009-12-01 00:00:00

abstract：OBJECTIVE:To investigate whether ultrasound determination of the inferior vena cava diameter (IVCD) and its collapsibility index (IVCCI) could be used to optimize the fluid removal rate while avoiding hypotension during slow continuous ultrafiltration (SCUF). METHODS:Twenty-four consecutive patients [13 men and 11 wom...

journal_title：Intensive care medicine

authors： Guiotto G,Masarone M,Paladino F,Ruggiero E,Scott S,Verde S,Schiraldi F

更新日期：2010-04-01 00:00:00

abstract：PURPOSE:To determine whether erythromycin is non-inferior to metoclopramide in facilitating post-pyloric placement of self-propelled spiral nasoenteric tubes (NETs) in critically ill patients. METHODS:A prospective, multicenter, open-label, parallel, and non-inferiority randomized controlled trial was conducted compar...

journal_title：Intensive care medicine

authors： Hu B,Ouyang X,Lei L,Sun C,Chi R,Guo J,Guo W,Zhang Y,Li Y,Huang D,Sun H,Nie Z,Yu J,Zhou Y,Wang H,Zhang J,Chen C

更新日期：2018-12-01 00:00:00

abstract：OBJECTIVES:A range of children receive extra-corporeal life support (ECLS) for respiratory failure, but there is little published data on this group. Our aims were: (1) to analyse predictors of outcome and (2) comment on inclusion and exclusion criteria. DESIGN:Retrospective review. SETTING:Tertiary ECLS centre. PAT...

journal_title：Intensive care medicine

authors： Pathan N,Ridout DA,Smith E,Goldman AP,Brown KL

更新日期：2008-12-01 00:00:00

abstract：OBJECTIVE:To test the hypothesis that levosimendan increases systemic and intestinal oxygen delivery (DO(2)) and prevents intramucosal acidosis in septic shock. DESIGN:Prospective, controlled experimental study. SETTING:University-based research laboratory. SUBJECTS:Nineteen anesthetized, mechanically ventilated she...

journal_title：Intensive care medicine

authors： Dubin A,Murias G,Sottile JP,Pozo MO,Barán M,Edul VS,Canales HS,Etcheverry G,Maskin B,Estenssoro E

更新日期：2007-03-01 00:00:00

abstract：:Induced hypothermia can be used to protect the brain from post-ischemic and traumatic neurological injury. Potential clinical applications and the available evidence are discussed in a separate paper. This review focuses on the practical aspects of cooling and physiological changes induced by hypothermia, as well as t...

journal_title：Intensive care medicine

authors： Polderman KH

更新日期：2004-05-01 00:00:00

abstract：:Pneumonia caused by herpes simplex virus type 1 (HSV1) is rare and occurs in severely immunosuppressed patients. HSV1 can be detected in bronchoalveolar lavage (BAL) from patients presenting with respiratory failure, but its direct effect on disease is difficult to prove. We demonstrate the causative role of HSV1 in t...

journal_title：Intensive care medicine

authors： François-Dufresne A,Garbino J,Ricou B,Wunderli W

更新日期：1997-03-01 00:00:00

abstract：:Central venous catheters (CVCs) are widely used in critically ill patients in intensive care units. However, infectious complications are common and may limit their utility. We critically review the literature to determine the impact of CVC design and composition, insertion site selection, insertion procedures, care a...

journal_title：Intensive care medicine

authors： Reed CR,Sessler CN,Glauser FL,Phelan BA

更新日期：1995-02-01 00:00:00

abstract：OBJECTIVE:To analyze the actual cost of pediatric intensive care and its different components, particularly the differences between various patient groups, with special reference to the variable cost and the elements included in it. DESIGN:Prospective, observational study. SETTING:Multidisciplinary 12-bed pediatric i...

journal_title：Intensive care medicine

authors： García S,Ruza F,Alvarado F,Madero R,Delgado MA,Dorao P,Frias M

更新日期：1997-02-01 00:00:00

abstract：PURPOSE:Meconium aspiration syndrome (MAS) is a life-threatening neonatal lung injury, whose pathophysiology has been mainly studied in animal models. In such models, pancreatic secretory phospholipase A2 (sPLA2-IB) and proinflammatory cytokines present in meconium challenge the lungs, catabolising surfactant and harmi...

journal_title：Intensive care medicine

authors： De Luca D,Minucci A,Tripodi D,Piastra M,Pietrini D,Zuppi C,Conti G,Carnielli VP,Capoluongo E

更新日期：2011-07-01 00:00:00

abstract：OBJECTIVE:To validate a simple method avoiding discard volumes in pediatric patients with indwelling arterial and venous lines. DESIGN:Zero-discarding was achieved by passive extracorporeal arteriovenous backflow via standard single pressure transducer equipment. We tested backflow distances (10, 20 and 30 cm beyond t...

journal_title：Intensive care medicine

authors： Weiss M,Fischer J,Boeckmann M,Rohrer B,Baenziger O

更新日期：2001-06-01 00:00:00

abstract：OBJECTIVE:To characterize N-terminal pro-brain natriuretic peptide (N-proBNP) and troponin I (TnI) profile following mitral and/or aortic valve surgery and to evaluate correlations with echocardiography measures and outcome criteria. DESIGN AND SETTING:Prospective cross-controlled study in a university children's hosp...

journal_title：Intensive care medicine

authors： Tissières P,da Cruz E,Habre W,Aggoun Y,Mensi N,Kalangos A,Beghetti M

更新日期：2008-06-01 00:00:00

abstract：OBJECTIVE:To determine the magnitude and time course of adrenergic effects on metabolism in volunteers and possible implications for the use of sympathomimetics in the critically ill. DESIGN:Descriptive laboratory investigation. SUBJECTS:7 volunteers. INTERVENTION:Primed continuous infusions of stable isotope tracer...

journal_title：Intensive care medicine

authors： Ensinger H,Träger K,Geisser W,Anhäupl T,Ahnefeld FW,Vogt J,Georgieff M

更新日期：1994-01-01 00:00:00

abstract：:Intravenous bolus endotoxin elicits a marked but transient increase in plasma TxB2 and 6-keto-PGF1 alpha in a large number of species. A smaller, delayed and more prolonged increase in TxB2 and 6-keto-PGF1 alpha are reported in animals with septic shock, i.e., those with fecal peritonitis or cecal ligation. Thromboxan...

journal_title：Intensive care medicine

authors： Ball HA,Cook JA,Wise WC,Halushka PV

更新日期：1986-01-01 00:00:00

abstract：PURPOSE:To determine the oxygen affinity for optimal tissue oxygen delivery with a hemoglobin-hydroxyethyl starch conjugate (HRC 101). METHODS:Anesthetized rats were hemodiluted (180 ml kg(-1)) with low (P(50) approximately 70 mmHg) or high affinity (P(50) approximately 14 mmHg) HRC 101 at hemoglobin (Hb) concentratio...

journal_title：Intensive care medicine

authors： Hare GM,Liu E,Baker AJ,Mazer CD

更新日期：2009-11-01 00:00:00

abstract：PURPOSE:Limited data exist on the correlation between higher flow rates of high-flow nasal cannula (HFNC) and its physiologic effects in patients with acute hypoxemic respiratory failure (AHRF). We assessed the effects of HFNC delivered at increasing flow rate on inspiratory effort, work of breathing, minute ventilatio...

journal_title：Intensive care medicine

authors： Mauri T,Alban L,Turrini C,Cambiaghi B,Carlesso E,Taccone P,Bottino N,Lissoni A,Spadaro S,Volta CA,Gattinoni L,Pesenti A,Grasselli G

更新日期：2017-10-01 00:00:00

abstract：PURPOSE:Type 1 angiotensin II (AT1) receptor antagonists have anti-inflammatory effects in vitro and in patients. The purpose of this study was to investigate whether losartan (LOS), an AT1 receptor antagonist, reduces lung damage by inhibiting the induction of high mobility group box 1 (HMGB1) protein and cytokines by...

journal_title：Intensive care medicine

authors： Hagiwara S,Iwasaka H,Hidaka S,Hasegawa A,Koga H,Noguchi T

更新日期：2009-08-01 00:00:00

abstract：OBJECTIVES:To analyse the clinical value of procalcitonin (PCT), C-reactive protein (CRP) and leucocyte count in the diagnosis of paediatric sepsis and in the stratification of patients according to severity. DESIGN:Prospective, observational study. SETTING:Paediatric intensive care unit (PICU). PATIENTS:Ninety-four...

journal_title：Intensive care medicine

authors： Rey C,Los Arcos M,Concha A,Medina A,Prieto S,Martinez P,Prieto B

更新日期：2007-03-01 00:00:00

abstract：:Dynamic vectorcardiography (VCG) is increasingly employed for ischaemia monitoring with the use of a computerized method for recording and on-line analysis by the calculation of trend parameters. To elucidate how well the derived electrocardiogram (dECG), calculated from the VCG, compares with the simultaneously regis...

journal_title：Intensive care medicine

authors： Gannedahl PE,Ljungqvist OH,Lundin P,Edner M

更新日期：1997-10-01 00:00:00

abstract：:This report identifies some of the risk factors underlying the acquisition of hospital infections in patients admitted to Intensive Care Units (ICUs). Infection rates vary in different institutes and in different types of ICUs. Patients are particularly prone to septicaemia and respiratory infections and the underlyin...

journal_title：Intensive care medicine

authors： Emmerson AM

更新日期：1990-01-01 00:00:00

abstract：:Extracorporeal CO2-removal (EC-CO2-R) using a membrane lung system was applied for 12 and 20 days respectively in two young men with adult respiratory distress syndrome (ARDS). Neuropathological examination revealed only moderate hypoxic changes of unusual distribution. In the first case nerve cell loss in Sommer's se...

journal_title：Intensive care medicine

authors： Krajewski S,Seitz RJ,Schober R,Breulmann M,Falke KJ

更新日期：1987-01-01 00:00:00

abstract：OBJECTIVE:Pseudomonas aeruginosa-induced lung injury is characterized not only by the alteration in lung fluid movement but also by apoptosis of lung epithelial and endothelial cells. We studied whether inhibition of apoptosis using a broad spectrum caspase inhibitor, benzyloxycarbonyl-Val-Ala-Asp fluoromethylketone (Z...

journal_title：Intensive care medicine

authors： Le Berre R,Faure K,Fauvel H,Viget NB,Ader F,Prangère T,Thomas AM,Leroy X,Pittet JF,Marchetti P,Guery BP

更新日期：2004-06-01 00:00:00

abstract：PURPOSE:Neurologic and endothelial injury biomarkers are associated with prolonged delirium during critical illness and may reflect injury pathways that lead to poor long-term outcomes. We hypothesized that blood-brain barrier (BBB), neuronal, and endothelial injury biomarkers measured during critical illness are assoc...

journal_title：Intensive care medicine

authors： Hughes CG,Patel MB,Brummel NE,Thompson JL,McNeil JB,Pandharipande PP,Jackson JC,Chandrasekhar R,Ware LB,Ely EW,Girard TD

更新日期：2018-03-01 00:00:00

abstract：PURPOSE:An International Consensus Conference proposed classifying weaning into simple, difficult, and prolonged weaning. However, the usefulness of this classification in a respiratory intensive care unit (ICU) is unknown. The aims of the study were: (1) to compare the clinical characteristics and outcomes of patients...

journal_title：Intensive care medicine

authors： Sellares J,Ferrer M,Cano E,Loureiro H,Valencia M,Torres A

更新日期：2011-05-01 00:00:00

abstract：PURPOSE:To assess the effects of alveolar recruitment maneuvers (ARMs) on clinical outcomes in patients with acute respiratory distress syndrome (ARDS). METHODS:We conducted a search of the MEDLINE, EMBASE, LILACS, CINAHL, CENTRAL, Scopus, and Web of Science (from inception to July 2014) databases for all (i.e. no lan...

journal_title：Intensive care medicine

authors： Suzumura EA,Figueiró M,Normilio-Silva K,Laranjeira L,Oliveira C,Buehler AM,Bugano D,Passos Amato MB,Ribeiro Carvalho CR,Berwanger O,Cavalcanti AB

更新日期：2014-09-01 00:00:00

abstract：:Owing to an oversight by the authors, Figure 2 in this article was not the version intended for publication. The correct Figure 2, reproduced here, features footnote symbols and Figure 2b includes three studies as described in the main text. ...

journal_title：Intensive care medicine

authors： Fujii T,Ganeko R,Kataoka Y,Furukawa TA,Featherstone R,Doi K,Vincent JL,Pasero D,Robert R,Ronco C,Bagshaw SM

更新日期：2018-02-01 00:00:00

abstract：:We analysed the case histories of 22 patients with life threatening asthma retrospectively. Fifteen patients needed mechanical ventilation. Three patients, all of them in cardiac arrest before or at the moment of admission, died. In five patients, halothane therapy was successfully used as a last resort. No major comp...

journal_title：Intensive care medicine

authors： Rosseel P,Lauwers LF,Baute L

更新日期：1985-01-01 00:00:00

abstract：OBJECTIVE:A closed suction system (CS) maintains connection with the mechanical ventilator during tracheal suctioning and is claimed to limit loss in lung volume and oxygenation. We compared changes in lung volume, oxygenation, airway pressure and hemodynamics during endotracheal suctioning performed with CS and with a...

journal_title：Intensive care medicine

authors： Cereda M,Villa F,Colombo E,Greco G,Nacoti M,Pesenti A

更新日期：2001-04-01 00:00:00

abstract：OBJECTIVE:Short-latency somatosensory evoked potential (SSEP) monitoring has been reported to be useful in predicting neurological outcome in patients with cardiac arrest and hypoxic-ischemic encephalopathy. To obtain the immediate data of SSEP and evaluate the relationship between the presence of cortical activity and...

journal_title：Intensive care medicine

authors： Nakabayashi M,Kurokawa A,Yamamoto Y

更新日期：2001-07-01 00:00:00

abstract：OBJECTIVES:To investigate at what time the peak level should be determined under conventional thrice daily (t.i.d.) administration of the aminoglycoside netilmicin and to study its serum concentrations under once daily (od) treatment to define the required daily dose and to gain information about convenient drug monito...

journal_title：Intensive care medicine

authors： Konrad F,Wagner R,Neumeister B,Rommel H,Georgieff M

更新日期：1993-01-01 00:00:00