Abstract:
OBJECTIVE:To determine the effect of cardiopulmonary bypass (CPB) on hepatic blood flow (HBF) and the hepatic venous flow pattern. DESIGN:Single-arm prospective study. SETTING:University hospital operating room and intensive care unit. PARTICIPANTS:Eight patients ranging in age from 57 to 73 years undergoing cardiac surgery. INTERVENTIONS:Transesophageal echocardiography (TEE) was used to assess HBF before, during, and after CPB by pulsed-wave Doppler ultrasound recordings of hepatic venous flow velocity and two-dimensional recordings of the hepatic vein diameter. Hepatic vein oxygenation was monitored by hepatic vein catheterization, and gastric intramucosal pH (pHi) was followed by tonometry. MEASUREMENTS AND MAIN RESULTS:The HBF was unchanged after the start of CPB but was reduced from the baseline value 415 (standard error of the mean 40) mL/min to 225 (25) mL/min during hypothermic CPB (p < 0.05). Cardiac index, right ventricular ejection fraction, and arterial and tonometric pH were essentially unchanged during the study period. Hepatic vein and mixed venous saturation were unchanged compared to control during CPB and were reduced at 2 and 3 hours after CPB (p < 0.01). Six of the patients had a normal predominant systolic flow pattern before surgery. In the postoperative period, seven patients showed an abnormal predominant diastolic filling pattern. CONCLUSIONS:TEE represents a useful tool in assessing changes in the hepatic blood flow. The HBF was reduced during hypothermic CPB, but this was not accompanied by a reduced pHi. The changes in the venous flow pattern with a reduction in systolic flow could be explained by impaired atrial relaxation.
journal_name
J Cardiothorac Vasc Anesthjournal_title
Journal of cardiothoracic and vascular anesthesiaauthors
Gårdebäck M,Settergren G,Brodin LAdoi
10.1016/s1053-0770(96)80090-5subject
Has Abstractpub_date
1996-04-01 00:00:00pages
318-22issue
3eissn
1053-0770issn
1532-8422pii
S1053-0770(96)80090-5journal_volume
10pub_type
杂志文章abstract:OBJECTIVE:The purpose of the present study was to examine resource utilization in octogenarians undergoing coronary artery bypass grafting (CABG) and compare it with usage in their younger cohorts at a tertiary care heart center. The resources examined were time to extubation, packed red blood cell transfusions, intens...
journal_title:Journal of cardiothoracic and vascular anesthesia
pub_type: 杂志文章
doi:10.1053/j.jvca.2005.03.030
更新日期:2005-10-01 00:00:00
abstract::To avoid intraoperative awareness and postoperative respiratory depression from high-dose opioid anesthesia, propofol (P), or isoflurane (I) has been combined with moderate-dose opioid with varying results. However, the effects of both P and I on myocardial contractility and left ventricular afterload have not been co...
journal_title:Journal of cardiothoracic and vascular anesthesia
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1016/s1053-0770(05)80050-3
更新日期:1995-02-01 00:00:00
abstract:OBJECTIVE:Continuous thermodilution cardiac output (CCO) measurement was clinically evaluated in patients who underwent coronary revascularization using hypothermic low-flow, low-pressure cardiopulmonary bypass (CPB). DESIGN:Prospective study. SETTING:University hospital setting. PARTICIPANTS:30 cardiac surgical pat...
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doi:10.1016/s1053-0770(05)80095-3
更新日期:1995-08-01 00:00:00
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journal_title:Journal of cardiothoracic and vascular anesthesia
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journal_title:Journal of cardiothoracic and vascular anesthesia
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doi:10.1053/j.jvca.2010.11.006
更新日期:2011-08-01 00:00:00
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更新日期:2016-04-01 00:00:00
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更新日期:2019-04-01 00:00:00
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journal_title:Journal of cardiothoracic and vascular anesthesia
pub_type: 杂志文章,随机对照试验
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更新日期:2006-08-01 00:00:00
abstract::In the UK, mortality rate during pregnancy/in the peripartal period is 14.1 per 100,000 maternities with heart disease being the leading cause of non-obstetric maternal mortality (10% to 15% of all maternal deaths). Owing to the advances in the treatment of congenital heart disease (CHD), an increasing percentage of w...
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更新日期:2020-12-01 00:00:00
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journal_title:Journal of cardiothoracic and vascular anesthesia
pub_type: 杂志文章,meta分析
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更新日期:2012-10-01 00:00:00
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更新日期:2018-06-01 00:00:00
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journal_title:Journal of cardiothoracic and vascular anesthesia
pub_type: 杂志文章
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更新日期:2020-12-01 00:00:00
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journal_title:Journal of cardiothoracic and vascular anesthesia
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更新日期:2020-12-13 00:00:00
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journal_title:Journal of cardiothoracic and vascular anesthesia
pub_type: 临床试验,杂志文章,随机对照试验
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更新日期:2001-04-01 00:00:00
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pub_type: 杂志文章,随机对照试验
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更新日期:2019-05-01 00:00:00
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pub_type: 杂志文章
doi:10.1053/j.jvca.2018.06.004
更新日期:2019-01-01 00:00:00
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journal_title:Journal of cardiothoracic and vascular anesthesia
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doi:10.1053/j.jvca.2007.10.013
更新日期:2008-06-01 00:00:00
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journal_title:Journal of cardiothoracic and vascular anesthesia
pub_type: 杂志文章
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journal_title:Journal of cardiothoracic and vascular anesthesia
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更新日期:2011-04-01 00:00:00
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更新日期:2014-04-01 00:00:00
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journal_title:Journal of cardiothoracic and vascular anesthesia
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更新日期:1991-08-01 00:00:00
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journal_title:Journal of cardiothoracic and vascular anesthesia
pub_type: 杂志文章,评审
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更新日期:1996-01-01 00:00:00
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journal_title:Journal of cardiothoracic and vascular anesthesia
pub_type: 杂志文章
doi:10.1053/j.jvca.2016.09.032
更新日期:2017-04-01 00:00:00
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journal_title:Journal of cardiothoracic and vascular anesthesia
pub_type: 杂志文章,随机对照试验
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更新日期:2011-12-01 00:00:00
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journal_title:Journal of cardiothoracic and vascular anesthesia
pub_type: 杂志文章
doi:10.1053/j.jvca.2014.06.017
更新日期:2014-12-01 00:00:00
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journal_title:Journal of cardiothoracic and vascular anesthesia
pub_type: 临床试验,杂志文章
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更新日期:2017-06-01 00:00:00
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journal_title:Journal of cardiothoracic and vascular anesthesia
pub_type: 杂志文章
doi:10.1053/jcan.2002.126952
更新日期:2002-10-01 00:00:00
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journal_title:Journal of cardiothoracic and vascular anesthesia
pub_type: 杂志文章
doi:10.1016/s1053-0770(05)80316-7
更新日期:1995-06-01 00:00:00
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journal_title:Journal of cardiothoracic and vascular anesthesia
pub_type: 杂志文章,随机对照试验
doi:10.1053/j.jvca.2011.07.026
更新日期:2011-12-01 00:00:00
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journal_title:Journal of cardiothoracic and vascular anesthesia
pub_type: 杂志文章
doi:10.1016/s1053-0770(98)90008-8
更新日期:1998-06-01 00:00:00