Microparticle immunoenzymatic assay for detection of prostate specific antigen: characterization of the technique and comparative analysis with a monoclonal immunoradiometric assay.

Abstract:

:Microparticle immunoenzymatic assay (MEIA) is a new, ultrasensitive technique recently introduced for detection of prostatic specific antigen (PSA). It is easily performed, totally automated, and cheaper and faster than radioimmunometric techniques. In this study, the levels of PSA in 194 males with urologic problems and healthy males, recorded by microparticle monoclonal ultrasensitive enzymoimmunoassay (MEIA) and immunoradiometric assay (IRMA), are comparatively evaluated. Variables recorded were age of patient, size and weight of the prostate, and PSA levels analyzed by the MEIA (MEIA-PSA) and IRMA (ELSA-PSA) techniques. Different determinations of PSA were performed in order to calculate the intra- and interassay variation coefficient for the MEIA-PSA assay. Means of prostatic length, width, and depth, recorded by ultrasonography, were 28.3, 35.8, and 31.4 mm, respectively, with a mean prostatic size of 19 ml and a mean prostatic weight of 23.9 g. Mean IRMA-PSA was 4.53 ng/ml and mean MEIA-PSA was 2.04 ng/ml. The difference between them was 2.49, and the ratio IRMA-PSA:MEIA-PSA was 3.17. Interassay and intraassay variation coefficients for MEIA-PSA were 6.58 and 9.96%, respectively. MEIA-PSA values correlated linearly with the age of the patients (r = 0.65, p = 0.0001), size of the prostate (r = 0.71, p = 0.0001), weight of the prostate (r = 0.71, p = 0.0001), and the value of IRMA-PSA (r = 0.80, p = 0.0001). Paired t tests showed that the values of PSA measured by MEIA and IRMA are statistically different (p = 0.0001), with independence of the level of PSA considered.

journal_name

Mil Med

journal_title

Military medicine

authors

Sánchez de la Muela P,Povo Castilla J,Bobillo de Lamo M,Rosales F,Pérez-Piqueras JL

subject

Has Abstract

pub_date

1995-08-01 00:00:00

pages

416-9

issue

8

eissn

0026-4075

issn

1930-613X

journal_volume

160

pub_type

杂志文章
  • Assessment of the Efficacy and Safety of a Novel, Low-Cost, Junctional Tourniquet in a Porcine Model of Hemorrhagic Shock.

    abstract:INTRODUCTION:Commercially available junctional tourniquets (JTQs) have several drawbacks. We developed a low-cost, compact, easy to apply JTQ. The aim of this study was to assess the tourniquets' safety and efficacy in a swine model of controlled hemorrhage. MATERIALS AND METHODS:Five pigs were subjected to controlled...

    journal_title:Military medicine

    pub_type: 杂志文章

    doi:10.1093/milmed/usz351

    authors: Nachman D,Dulce D,Wagnert-Avraham L,Gavish L,Mark N,Gerrasi R,Gertz SD,Eisenkraft A

    更新日期:2020-01-07 00:00:00

  • Stinging the Conscience: A Case of Severe Hymenoptera Anaphylaxis and the Need for Provider Awareness.

    abstract::Hymenoptera venom allergy accounts for approximately 17% of all cases of anaphylaxis. Insect stings are a common occurrence across the world, with significant impact on active duty personnel. Venom immunotherapy (VIT) provides an effective treatment for those with systemic reactions to insect stings and other similar ...

    journal_title:Military medicine

    pub_type: 杂志文章

    doi:10.7205/MILMED-D-15-00536

    authors: Mikals K,Beakes D,Banks TA

    更新日期:2016-10-01 00:00:00

  • Inpatient care for the aircraft carrier battle group.

    abstract::A case series of 417 consecutive ward admissions onboard the USS Forrestal (CV59) is presented. During the 1-year study period, the inpatient ward was open for 260 days while the ship was underway, including workups and extended Mediterranean deployment. The case series displays the variety of clinical inpatient care ...

    journal_title:Military medicine

    pub_type: 杂志文章

    doi:

    authors: Bohnker BK

    更新日期:1995-06-01 00:00:00

  • Pressure ulcers and occipital alopecia in Operation Iraqi Freedom polytrauma casualties.

    abstract:OBJECTIVE:Several of the casualties from Operation Iraqi Freedom arriving at one Veterans Administration (VA) polytrauma rehabilitation center (PRC) were noted to have occipital pressure ulcers or hair loss. The objective of this study was to determine the prevalence and severity of pressure-related injuries in VA PRC ...

    journal_title:Military medicine

    pub_type: 杂志文章

    doi:10.7205/milmed.173.11.1068

    authors: Harrow JJ,Rashka SL,Fitzgerald SG,Nelson AL

    更新日期:2008-11-01 00:00:00

  • Rubber matting on an obstacle course causes anterior cruciate ligament ruptures and its removal eliminates them.

    abstract::In June 1998, six unexpected anterior cruciate ligament (ACL) ruptures within 12 months were detected by routine injury surveillance in a cohort of Australian Army recruits. Local investigation, reported separately as a Case Report in this issue, suggested the cause to be an excessive coefficient of friction between r...

    journal_title:Military medicine

    pub_type: 杂志文章

    doi:

    authors: Pope RP

    更新日期:2002-04-01 00:00:00

  • Exertional myalgia syndrome associated with diminished serum ammonia elevation in ischemic exercise testing.

    abstract::A 36-year-old man with chronic severe exertional myalgias had a normal serum lactate elevation and diminished serum ammonia elevation on an ischemic forearm exercise test (IFET). The IFET is commonly performed in the evaluation of patients with complaints of exertional myalgias, cramps, and rhabdomyolysis. The finding...

    journal_title:Military medicine

    pub_type: 杂志文章

    doi:

    authors: Riggs JE,Schochet SS Jr,Webb RW

    更新日期:1999-09-01 00:00:00

  • Occupational Therapy Practice Patterns for Military Service Members With Upper Limb Amputation.

    abstract:INTRODUCTION:Military Service Members (SMs) with upper limb (UL) amputation have unrestricted access to occupational therapy (OT) services. Identifying OT interventions used based on clinical rationale and patient needs can provide insight toward developing best practice guidelines. The purpose of this retrospective ob...

    journal_title:Military medicine

    pub_type: 杂志文章

    doi:10.1093/milmed/usz341

    authors: Cancio JM,Orr A,Eskridge S,Shannon K,Mazzone B,Farrokhi S

    更新日期:2020-03-02 00:00:00

  • Developing and Testing a Web-Based Provider Training for Cognitive Behavioral Therapy of Insomnia.

    abstract:INTRODUCTION:Chronic insomnia is a common and debilitating disease that increases risk for significant morbidity and workplace difficulties. Cognitive behavioral therapy for insomnia (CBT-I) is the first-line treatment, but there is a critical lack of behavioral health providers trained in CBT-I because, in part, of a ...

    journal_title:Military medicine

    pub_type: 杂志文章

    doi:10.1093/milmed/usaa359

    authors: Taylor DJ,Dietch JR,Pruiksma K,Calhoun CD,Milanak ME,Wardle-Pinkston S,Rheingold AA,Ruggiero KJ,Bunnell BE,Wilkerson AK

    更新日期:2021-01-25 00:00:00

  • High-intensity tasks with external load in military applications: a review.

    abstract::This article provides a synopsis of the limited investigations examining the impact of external load (EL) on performance of high-intensity tasks under load (HITL), EL training intervention effects on HITL performance, and injuries from EL training. Repetitive lifting tasks and initiation of locomotion, such as rapidly...

    journal_title:Military medicine

    pub_type: 杂志文章,评审

    doi:10.7205/MILMED-D-14-00079

    authors: O'Neal EK,Hornsby JH,Kelleran KJ

    更新日期:2014-09-01 00:00:00

  • Screening military dependent adolescent females for disordered eating.

    abstract::Eating disorders are increasing in frequency among adolescents. The active duty military population has a high prevalence of eating disorders. This study, conducted at a major medical center, determined the prevalence of disordered eating among military dependents and the correlation between adolescent and parent eati...

    journal_title:Military medicine

    pub_type: 杂志文章

    doi:10.7205/milmed.172.9.962

    authors: Waasdorp CE,Caboot JB,Robinson CA,Abraham AA,Adelman WP

    更新日期:2007-09-01 00:00:00

  • Urinary incontinence among female soldiers.

    abstract::A self-administered questionnaire was developed to assess the prevalence of urinary incontinence among active duty female soldiers. The questionnaire also addressed basic demographic information, including height, age, weight, and the subjects' present and past military activities. Adaptive measures that the soldiers ...

    journal_title:Military medicine

    pub_type: 杂志文章

    doi:

    authors: Davis G,Sherman R,Wong MF,McClure G,Perez R,Hibbert M

    更新日期:1999-03-01 00:00:00

  • Preoperative Chlorhexidine Gluconate Bathing on a Military Medical-Surgical Unit.

    abstract:INTRODUCTION AND SCOPE OF THE PROBLEM:Surgical site infections (SSIs) are associated with increased length of hospital stays, poor patient outcomes, and increased health care costs making prevention of SSI a high priority for the U.S. Military Health Care System. The focus of this project was to develop and pilot a pre...

    journal_title:Military medicine

    pub_type: 杂志文章

    doi:10.1093/milmed/usz186

    authors: Scallan RM,Gerathy S,Price J,Lazarus AM,Metter EJ,Talbot LA

    更新日期:2020-06-19 00:00:00

  • Fluticasone as Treatment for Cluster Headaches in a Navy Aircrew Member.

    abstract::Cluster headaches (CHs) are one of the most debilitating of all the identified headache syndromes. Their pathogenesis is poorly understood, which has made their treatment challenging. Various medicines and modalities have been put forth in an effort to minimize the symptoms, but none have proven to be consistently rel...

    journal_title:Military medicine

    pub_type: 杂志文章

    doi:10.7205/MILMED-D-14-00713

    authors: Andicochea CT,Blalack PM,Fulkerson JA,Kidd GA,Taylor BM

    更新日期:2015-10-01 00:00:00

  • Validation of Laboratory Animal and Surrogate Human Models in Primary Blast Injury Studies.

    abstract::Blast-induced neurotrauma has affected more than 300,000 service members. It is important to understand the effect of single and repeated shock-blast wave exposures on the neuropsychological behavior of soldiers, to offer them better protection, diagnostics, and treatment. Preclinical animal models and helmet design s...

    journal_title:Military medicine

    pub_type: 杂志文章

    doi:10.7205/MILMED-D-16-00144

    authors: Chandra N,Sundaramurthy A,Gupta RK

    更新日期:2017-03-01 00:00:00

  • Delayed traumatic occlusion of the extracranial internal carotid artery after earthquake: report of two cases.

    abstract::We report on two patients with head and neck injuries, who remained asymptomatic after the earthquake for 1 and 2 years, respectively. They developed late transient ischemic neurological signs and eventually presented with complete occlusion of the internal carotid artery. They made a good recovery with medical treatm...

    journal_title:Military medicine

    pub_type: 杂志文章

    doi:10.7205/milmed.169.7.556

    authors: Bozkurt AK,Kara B,Ciftçi E,Budak F

    更新日期:2004-07-01 00:00:00

  • Overview of overseas humanitarian, disaster, and civic aid programs.

    abstract::The U.S. Department of Defense (DoD) conducts humanitarian assistance missions under the Overseas Humanitarian Disaster and Civic Aid program for the statutory purposes of training military personnel, serving the political interests of the host nation and United States, and providing humanitarian relief to foreign civ...

    journal_title:Military medicine

    pub_type: 杂志文章

    doi:

    authors: Drifmeyer J,Llewellyn C

    更新日期:2003-12-01 00:00:00

  • Serial Echocardiographic Follow-up of Structural Heart Interventions Performed During Pacific Partnership Interventional Cardiology Subject Matter Exchanges From 2015 to 2017 in Da Nang, Vietnam.

    abstract:INTRODUCTION:The U.S. Navy Medicine has a long history of conducting global health missions that foster international diplomacy through medical knowledge exchange with a goal of increasing partner nation's health care capacity. Pacific Partnership is an annual U.S. Navy-sponsored joint operation that enhances medical c...

    journal_title:Military medicine

    pub_type: 杂志文章

    doi:10.1093/milmed/usaa499

    authors: Nayak KR,Trieu NB,O'Dell J,Kendall S,Stanton K,Thanh Han NH,Krause D,Wessman D,Lopez J,Phi-Lee T,Adams D,Parrish JS,LanHieu N

    更新日期:2021-01-25 00:00:00

  • World War II military led the way in screening chest radiography.

    abstract::World War I recruits were screened for tuberculosis almost exclusively with a history and physical exam. Radiography was unavailable on a large scale and expensive. New techniques developed in Brazil and elsewhere in the 1930s made mass radiographic screening practical. During World War II, the U.S. Army and Navy took...

    journal_title:Military medicine

    pub_type: 历史文章,杂志文章

    doi:

    authors: Haygood TM,Briggs JE

    更新日期:1992-03-01 00:00:00

  • Metabolic parameters that predict response to clomiphene citrate in obese oligo-ovulatory women.

    abstract:OBJECTIVE:To determine whether the presence of insulin resistance in obese subjects would adversely affect the rate of ovulation induction by clomiphene citrate. RESULTS:Fasting hyperinsulinemia was associated with the failure to ovulate in response to clomiphene. In addition, other parameters found to correlate with ...

    journal_title:Military medicine

    pub_type: 杂志文章

    doi:

    authors: Armstrong AB,Hoeldtke N,Wiess TE,Tuttle RM,Jones RE

    更新日期:1996-12-01 00:00:00

  • Gluteal gunshot wounds.

    abstract::Experience with advanced surgery for the treatment of civilian gunshot injuries supports the changes in approach and indications for the treatment of war gunshot injuries. Eight patients with gluteal gunshot wounds are presented with typical war injuries. They were wounded during 1992 and 1993 in the war in Croatia an...

    journal_title:Military medicine

    pub_type: 杂志文章

    doi:

    authors: Vukić Z

    更新日期:2000-03-01 00:00:00

  • Improving the adoption of evidence-based practice among nurses in Army outpatient medical treatment facilities.

    abstract::This quality improvement project implemented and evaluated an evidence-based practice (EBP) program at two Army outpatient health care facilities. The EBP program consisted of five implementation strategies that aimed to inculcate EBP into organizational culture as well as nursing practice and culture. A conceptual mo...

    journal_title:Military medicine

    pub_type: 临床试验,杂志文章

    doi:10.7205/MILMED-D-13-00191

    authors: Yackel EE,Short NM,Lewis PC,Breckenridge-Sproat ST,Turner BS

    更新日期:2013-09-01 00:00:00

  • A survey of Army Medical Department personnel beliefs about domestic violence.

    abstract::Army health care personnel play a key role in the Army's Family Advocacy Program, yet little is known about their beliefs toward domestic violence. This study surveyed the beliefs of selected Army Medical Department personnel concerning the extent, nature, causes, and management of spouse abuse. The study suggests tha...

    journal_title:Military medicine

    pub_type: 杂志文章

    doi:

    authors: Hamlin ER 2nd,Donnewwerth D,Georgoulakis JM

    更新日期:1991-09-01 00:00:00

  • Co-occurrent use of cigarettes, alcohol, and caffeine in a retired military population.

    abstract::Previous studies have linked the use of caffeine, nicotine, and alcohol to health complications and have also found that the use of these substances significantly covary. Given the prevalence of health problems of older adults, it is surprising that no studies to date have examined the co-occurrent use of alcohol, caf...

    journal_title:Military medicine

    pub_type: 杂志文章

    doi:

    authors: Talcott GW,Poston WS 2nd,Haddock CK

    更新日期:1998-03-01 00:00:00

  • Crush syndrome and acute renal failure in the Marmara earthquake.

    abstract::In this study, patients with acute renal failure as a result of crush syndrome after the Marmara earthquake were evaluated retrospectively. Six hundred thirty injured patients were evaluated after the Marmara earthquake at Gülhane Military Medical Academy. Acute renal failure in association with crush syndrome develop...

    journal_title:Military medicine

    pub_type: 杂志文章

    doi:

    authors: Poçan S,Ozkan S,Us MH,Cakir O,Gökben M

    更新日期:2002-06-01 00:00:00

  • Delay in improvement of ankle-arm index and ankle waveforms after lower-extremity revascularization.

    abstract::Ankle-arm index (AAI) and pulse volume recording (PVR) are commonly used in the early postoperative period to measure the outcome after lower-extremity revascularization. They are also used in addition to duplex scan for long-term follow-up of these patients. We noticed that in some patients the AAI and/or PVR after r...

    journal_title:Military medicine

    pub_type: 杂志文章

    doi:

    authors: Tripathi S,Farid A,Deshmukh N

    更新日期:1997-04-01 00:00:00

  • Joint civilian/national guard mass casualty exercise provides model for preparedness training.

    abstract::After-action reports on the 2005 hurricane relief efforts pointed to the need for effective and efficient civilian/military operational cooperation. Cited for particular attention was the interface with National Guard units. This article describes an exercise conducted with National Guard units and members of the Cent...

    journal_title:Military medicine

    pub_type: 杂志文章

    doi:10.7205/milmed.172.8.806

    authors: Grant WD,Secreti L

    更新日期:2007-08-01 00:00:00

  • Listening to the Patient: Women Veterans' Insights About Health Care Needs, Access, and Quality in Rural Areas.

    abstract:OBJECTIVES:Many work to ensure that women veterans receive appropriate and timely health care, yet the needs of those living in rural areas are often ignored. This is a critical oversight given the multitude of reports documenting rural access problems and health disparities. Lacking this, we are unable to plan for and...

    journal_title:Military medicine

    pub_type: 杂志文章

    doi:10.7205/MILMED-D-15-00367

    authors: Brooks E,Dailey NK,Bair BD,Shore JH

    更新日期:2016-09-01 00:00:00

  • Disinfection of Acinetobacter baumannii-contaminated surfaces relevant to medical treatment facilities with ultraviolet C light.

    abstract::The efficacy of ultraviolet C (UVC) light (100-280 nm) in the decontamination of three hospital-related surfaces, namely, unpainted/painted aluminum (bed railings), stainless steel (operating tables), and scrubs (laboratory coats), was investigated. Acinetobacter baumannii cells were inoculated (10(5) or 10(3) cells) ...

    journal_title:Military medicine

    pub_type: 杂志文章

    doi:10.7205/milmed.172.11.1166

    authors: Rastogi VK,Wallace L,Smith LS

    更新日期:2007-11-01 00:00:00

  • Military gunshot wound-induced spinal cord injuries.

    abstract::Gunshot wounds are the second leading cause of spinal cord injuries in developed countries, whereas in undeveloped and developing countries, this likelihood is much more. However, the weapon and injury characteristics are very different between those two groups of countries. The aim of this study was to review our exp...

    journal_title:Military medicine

    pub_type: 杂志文章

    doi:

    authors: Alaca R,Yilmaz B,Goktepe AS,Yazicioglu K,Gunduz S

    更新日期:2002-11-01 00:00:00

  • Ooh-rah! An unusual cause of spontaneous pneumomediastinum.

    abstract::Spontaneous pneumomediastinum (SPM) with associated subcutaneous emphysema is an uncommon and generally benign condition. We describe an occurrence of SPM that occurred from yelling in a U.S. Marine Corps Drill Instructor. The patient describes yelling at Marine recruits the day prior when he felt a pop "behind his no...

    journal_title:Military medicine

    pub_type: 杂志文章

    doi:10.7205/milmed-d-12-00243

    authors: Singla M,Potocko J,Sanstead J,Pepper P

    更新日期:2012-11-01 00:00:00