当前位置： SCI文献检索 > HUMAN GENETICS期刊下所有文献 > Premeiotic and early meiotic stages in the pollen mother cells of Eremurus and in human embryonic oocytes.

Premeiotic and early meiotic stages in the pollen mother cells of Eremurus and in human embryonic oocytes.

Abstract：

:The premeiotic and meiotic stages are described in the pollen mother cells of the liliaceous plant Eremurus. In human oocytes from embryonic ovaries, the premeiotic and early meiotic stages up to dictyotene have been identified on morphological grounds. In Eremurus, in which each stage can be independently verified by the sequence of buds situated in a spiral, there is no indication of somatic pairing of homologous chromosomes, nor is there any sign of a premeiotic contraction of the chromosomes. The interphase following this mitosis is, in turn, succeeded by leptotene in which the DNA synthesis occurs, as determined by using autoradiography. This stage is followed by a "distance pairing" stage in which the homologous chromosomes lie parallel to each other at a distance. In typical zygotene, segments of chromosomes are paired intimately, others are unpaired, and the points at which pairing begins and ends are clearly visible. Each bivalent shows several pairing blocks. Pairing is completed at pachytene; diplotene which is characterized by the separation of the chromosomes follows. In mid-diplotene the chromosomes collect together in the so-called second contraction stage. The same meiotic prophase stages that occur in Eremurus, including the "distance pairing" stage, are found in the embryonic human oocytes. In the last premeiotic interphase, the chromosomes appear as condensed prochromosomes which unravel directly to form the leptotene chromosomes. In the oocytes, too, DNA synthesis seems to take place in leptotene.

journal_name

Hum Genet

journal_title

Human genetics

authors

Therman E,Sarto GE

doi

10.1007/BF00393963

subject

Has Abstract

pub_date

1977-02-11 00:00:00

pages

137-51

issue

2

eissn

0340-6717

issn

1432-1203

journal_volume

35

pub_type

杂志文章

相关文献

HUMAN GENETICS文献大全
  • Correction to: Runs of homozygosity in sub-Saharan African populations provide insights into complex demographic histories.

    abstract：:In the Original article published, the figure number 5: Genomic distribution of ROH is incorrectly published. The correct figure is given below. ...

    journal_title：Human genetics

    pub_type： 已发布勘误

    doi：10.1007/s00439-019-02053-1

    authors： Ceballos FC,Hazelhurst S,Ramsay M

    更新日期：2019-10-01 00:00:00

  • A new translocation in chronic myelogenous leukemia.

    abstract：:A reciprocal translocation involving chromosomes Nos. 3 and 22 has been found in a patient with seemingly Ph-negative chronic myelogenous leukemia (CML). G-band analysis revealed, that deletion in No. 22 occurred at the same point, as in the typical cases of the disease. It was concluded, that breakage in No. 22 at a ...

    journal_title：Human genetics

    pub_type： 杂志文章

    doi：10.1007/BF00291511

    authors： Pravtcheva D,Andreeva P,Tsaneva R

    更新日期：1976-05-19 00:00:00

  • Molecular characterization of a ring chromosome 14 showing that the PI locus is centromeric to the D14S1 and IGH loci.

    abstract：:Molecular characterization of a ring chromosome 14 was carried out in a patient with the 46,XX,r(14) karyotype. The breakpoints shown by chromosome banding were within bands p11 and q32. Using molecular probes for the immunoglobulin heavy chain (IGH), D14S1 and PI loci located at 14q32, we showed that the IGH and D14S...

    journal_title：Human genetics

    pub_type： 杂志文章

    doi：10.1007/BF00291158

    authors： Keyeux G,Gilgenkrantz S,Lefranc G,Lefranc MP

    更新日期：1989-06-01 00:00:00

  • Pure gonadal dysgenesis (type XX). Report on a family with four affected sibs.

    abstract：:A family with four 46,XX siblings affected by the pure gonadal dysgenesis syndrome is described. Inheritance is by an autosomal recessive gene limited to the female sex. ...

    journal_title：Human genetics

    pub_type： 杂志文章

    doi：10.1007/BF00293782

    authors： Nazareth HR,Farah LM,Cunha AJ,Vieira FJ

    更新日期：1977-06-10 00:00:00

  • Allele-specific transcription factor binding to common and rare variants associated with disease and gene expression.

    abstract：:Genome-wide association studies (GWAS) have identified a large number of disease-associated SNPs, but in few cases the functional variant and the gene it controls have been identified. To systematically identify candidate regulatory variants, we sequenced ENCODE cell lines and used public ChIP-seq data to look for tra...

    journal_title：Human genetics

    pub_type： 杂志文章

    doi：10.1007/s00439-016-1654-x

    authors： Cavalli M,Pan G,Nord H,Wallerman O,Wallén Arzt E,Berggren O,Elvers I,Eloranta ML,Rönnblom L,Lindblad Toh K,Wadelius C

    更新日期：2016-05-01 00:00:00

  • An estimate of genetic risk from 8-methoxypsoralen photochemotherapy.

    abstract：:A method based on a combination of cell culture and pharmacokinetic data is explored as a way of estimating the possible genetic risk to man from a mutagenic chemical. 8-methoxypsoralen, which is given to psoriasis patients as part of a photochemotherapy regime, is used, since it represents a 'real-life' situation and...

    journal_title：Human genetics

    pub_type： 杂志文章

    doi：10.1007/BF00277690

    authors： Bridges BA

    更新日期：1979-05-23 00:00:00

  • Whole-genome sequencing in French Canadians from Quebec.

    abstract：:Genome-wide association studies (GWAS) have had a tremendous success in the identification of common DNA sequence variants associated with complex human diseases and traits. However, because of their design, GWAS are largely inappropriate to characterize the role of rare and low-frequency DNA variants on human phenoty...

    journal_title：Human genetics

    pub_type： 杂志文章

    doi：10.1007/s00439-016-1702-6

    authors： Low-Kam C,Rhainds D,Lo KS,Provost S,Mongrain I,Dubois A,Perreault S,Robinson JF,Hegele RA,Dubé MP,Tardif JC,Lettre G

    更新日期：2016-11-01 00:00:00

  • CRISPR/Cas9-mediated somatic and germline gene correction to restore hemostasis in hemophilia B mice.

    abstract：:Hemophilia B (HB) is an X-linked disorder caused by defects of F9 encoded coagulation factor IX, which is an ideal model for gene therapy. Most existing HB gene therapies are based on viral mediated gene supplementation, which could increase immunoreaction. In this study, CRISPR/Cas9 system was used for gene correctio...

    journal_title：Human genetics

    pub_type： 杂志文章

    doi：10.1007/s00439-017-1801-z

    authors： Huai C,Jia C,Sun R,Xu P,Min T,Wang Q,Zheng C,Chen H,Lu D

    更新日期：2017-07-01 00:00:00

  • Assignment of human coagulation factor XII (fXII) to chromosome 5 by cDNA hybridization to DNA from somatic cell hybrids.

    abstract：:Human coagulation factor XII (fXII), a serine protease synthesized in liver and active in plasma, is involved in a wide variety of functions, including blood coagulation, fibrinolysis, bradykinin and complement activation. A complementary DNA (597 bp) encoding amino acid -16 to amino acid 183 of fXII protein was used ...

    journal_title：Human genetics

    pub_type： 杂志文章

    doi：10.1007/BF00273661

    authors： Citarella F,Tripodi M,Fantoni A,Bernardi F,Romeo G,Rocchi M

    更新日期：1988-12-01 00:00:00

  • A novel locus for distal motor neuron degeneration maps to chromosome 7q34-q36.

    abstract：:The motor neuron diseases (MND) are a group of related neurodegenerative diseases that cause the relative selective progressive death of motor neurons. These diseases range from slowly progressive forms including hereditary motor neuropathy (HMN), to the rapidly progressive disorder amyotrophic lateral sclerosis (ALS)...

    journal_title：Human genetics

    pub_type： 杂志文章

    doi：10.1007/s00439-007-0348-9

    authors： Gopinath S,Blair IP,Kennerson ML,Durnall JC,Nicholson GA

    更新日期：2007-06-01 00:00:00

  • Malformative syndrome associated with a ring 10 chromosome and a translocated 10q/19 chromosome.

    abstract：:A male newborn with a ring 10 chromosome is described. The distal part of the long arm of chromosome 10, deleted during ring formation (10q25), is translocated to the short arm of chromosome 19. ...

    journal_title：Human genetics

    pub_type： 杂志文章

    doi：10.1007/BF00293602

    authors： Fryns JP,De Boeck K,Jaeken J,van den Berghe H

    更新日期：1978-08-31 00:00:00

  • Genomic markers to tailor treatments: waiting or initiating?

    abstract：:The decade since the publication of the Human Genome Project draft has ended with the discovery of hundreds of genomic markers related to diseases and phenotypes. However, the project has not yet delivered on its promise to tailor treatments for individuals. The number of genomic markers in clinical practice is very s...

    journal_title：Human genetics

    pub_type： 杂志文章

    doi：10.1007/s00439-011-0986-9

    authors： Tajik P,Bossuyt PM

    更新日期：2011-07-01 00:00:00

  • Fetal gender determination in early pregnancy through qualitative and quantitative analysis of fetal DNA in maternal serum.

    abstract：:Fetal DNA in maternal plasma and serum has been shown to be a useful material for fetal gender determination and for screening tests for abnormal pregnancies except during early gestational ages. Maternal serum samples were obtained from 81 pregnant women during the 5th-10th weeks of gestation. Fetal gender was determ...

    journal_title：Human genetics

    pub_type： 杂志文章

    doi：10.1007/s00439-001-0649-3

    authors： Honda H,Miharu N,Ohashi Y,Samura O,Kinutani M,Hara T,Ohama K

    更新日期：2002-01-01 00:00:00

  • The human apolipoprotein B 3' hypervariable region: detection of eight new alleles and comparisons of allele frequencies in blacks and whites.

    abstract：:We investigated common length polymorphisms in the hypervariable region located 3' to the human gene encoding apolipoprotein B (APOB 3' HVR) as part of the "Pathobiological Determinants of Atherosclerosis in Youth (PDAY)" study. PDAY is a multicenter study of young persons who died of external causes (accident, homici...

    journal_title：Human genetics

    pub_type： 杂志文章,多中心研究

    doi：10.1007/BF00217775

    authors： Hixson JE,Powers PK,McMahan CA

    更新日期：1993-06-01 00:00:00

  • Arginase deficiency manifesting delayed clinical sequelae and induction of a kidney arginase isozyme.

    abstract：:Deficiency of liver arginase (AI) is characterized clinically by hyperargininemia, progressive mental impairment, growth retardation, spasticity, and periodic episodes of hyperammonemia. The rarest of the inborn errors of urea cycle enzymes, it has been considered the least life-threatening, by virtue of the typical a...

    journal_title：Human genetics

    pub_type： 杂志文章

    doi：10.1007/BF00230212

    authors： Grody WW,Kern RM,Klein D,Dodson AE,Wissman PB,Barsky SH,Cederbaum SD

    更新日期：1993-03-01 00:00:00

  • Confined chorionic mosaicism in prenatal diagnosis.

    abstract：:Confined chorionic mosaicism, detected commonly on chorionic villus sampling (CVS) and occasionally in cultured amniotic fluid cells, is described in five pregnancies that showed confined chorionic mosaicism for trisomies 12, 13, 14, 17 and a marker chromosome. Cytogenetic findings in these pregnancies support the con...

    journal_title：Human genetics

    pub_type： 杂志文章

    doi：10.1007/BF00272385

    authors： Kalousek DK,Dill FJ,Pantzar T,McGillivray BC,Yong SL,Wilson RD

    更新日期：1987-10-01 00:00:00

  • Absence of correlation between late-replication and spreading of X inactivation in an X;autosome translocation.

    abstract：:We have analysed the spread of X inactivation in an individual with an unbalanced 46,X,der(X)t(X;10)(q26.3;q23.3) karyotype. Despite being trisomic for the region 10q23.3-qter, both the proband and her aunt with the same karyotype presented only with secondary amenorrhoea and lacked any features normally associated wi...

    journal_title：Human genetics

    pub_type： 杂志文章

    doi：10.1007/s004390100578

    authors： Sharp A,Robinson DO,Jacobs P

    更新日期：2001-09-01 00:00:00

  • B-cell-negative severe combined immunodeficiency associated with a common gamma chain mutation.

    abstract：:Severe combined immunodeficiency (SCID) is caused by a variety of underlying defects. Approximately 40% of cases are thought to be of the X-linked type (SCIDX1), which is phenotypically characterised by the absence, or very low numbers, of T cells, but normal or even high B cell numbers. The gene responsible for SCIDX...

    journal_title：Human genetics

    pub_type： 杂志文章

    doi：10.1007/s004390050428

    authors： Jones AM,Clark PA,Katz F,Genet S,McMahon C,Alterman L,Cant A,Kinnon C

    更新日期：1997-05-01 00:00:00

  • MECP2 mutations in Rett syndrome adversely affect lymphocyte growth, but do not affect imprinted gene expression in blood or brain.

    abstract：:Rett syndrome (RTT) is an X-linked dominant neurodevelopmental disorder caused by mutations in MECP2, encoding methyl-CpG-binding protein 2 (MeCP2). As female somatic cells are mosaic for expression of mutant MECP2, we performed single cell cloning of T lymphocytes from four RTT patients with MECP2 mutations to isolat...

    journal_title：Human genetics

    pub_type： 杂志文章

    doi：10.1007/s00439-002-0724-4

    authors： Balmer D,Arredondo J,Samaco RC,LaSalle JM

    更新日期：2002-06-01 00:00:00

  • Translocation t(1;17)(q12;q25) with a clinical picture like of a proximal deletion of 1q: identification by in situ hybridization with chromosome 1-specific satellite DNA probes.

    abstract：:The authors report a case of a balanced 1;17 translocation with breakpoints located in the secondary constriction of chromosome 1. This translocation is associated with pathological symptoms similar to those observed following a proximal deletion of 1q. We request contact with colleques who have observed similar, or r...

    journal_title：Human genetics

    pub_type： 杂志文章

    doi：10.1007/BF00197700

    authors： Vorsanova SG,Yurov YB,Kurbatov MB,Kazantzeva LZ

    更新日期：1990-12-01 00:00:00

  • DNA semi-conservative synthesis in normal and Fanconi anemia fibroblasts following treatment with 8-methoxypsoralen and near ultraviolet light or with X-rays.

    abstract：:The effect of treatment with 8-methoxypsoralen (8-MOP) plus near-UV radiation (UVA) or with X-rays on the rate of DNA semi-conservative synthesis of fibroblasts from 10 Fanconi anemia (FA), two heterozygous, and three normal cell lines was studied. Following treatments with either X-rays or low doses of 8-MOP plus UVA...

    journal_title：Human genetics

    pub_type： 杂志文章

    doi：10.1007/BF00273448

    authors： Moustacchi E,Diatloff-Zito C

    更新日期：1985-01-01 00:00:00

  • How meaningful are heritability estimates of liability?

    abstract：:It is commonly acknowledged that estimates of heritability from classical twin studies have many potential shortcomings. Despite this, in the post-GWAS era, these heritability estimates have come to be a continual source of interest and controversy. While the heritability estimates of a quantitative trait are subject ...

    journal_title：Human genetics

    pub_type： 杂志文章

    doi：10.1007/s00439-013-1334-z

    authors： Benchek PH,Morris NJ

    更新日期：2013-12-01 00:00:00

  • Sex ratio of the mutation frequencies in haemophilia A: estimation and meta-analysis.

    abstract：:A hereditary disease with excess mortality such as haemophilia is maintained in the population by the occurrence of new cases, i.e. mutations. In haemophilia, mutations may arise in female or male ancestors of a 'new' patient. The ratio of the mutation frequencies in males over females determines the prior risk of car...

    journal_title：Human genetics

    pub_type： 杂志文章,meta分析

    doi：10.1007/BF00197695

    authors： Rosendaal FR,Bröcker-Vriends AH,van Houwelingen JC,Smit C,Varekamp I,van Dijck H,Suurmeijer TP,Vandenbroucke JP,Briët E

    更新日期：1990-12-01 00:00:00

  • Gene assignment of Zellweger syndrome to 7q11.23: report of the second case associated with a pericentric inversion of chromosome 7.

    abstract：:The case of a newborn girl with Zellweger syndrome and a pericentric inversion of chromosome 7, 46,XX, inv(7)(p12q11.23), is reported. The diagnosis was confirmed by marked deficiency of peroxisomal beta-oxidation enzymes in hepatic cells from autopsy samples. This is the second case of Zellweger syndrome associated w...

    journal_title：Human genetics

    pub_type： 杂志文章

    doi：10.1007/BF00210677

    authors： Naritomi K,Izumikawa Y,Ohshiro S,Yoshida K,Shimozawa N,Suzuki Y,Orii T,Hirayama K

    更新日期：1989-12-01 00:00:00

  • A common variant in CLDN14 causes precipitous, prelingual sensorineural hearing loss in multiple families due to founder effect.

    abstract：:Genetic isolates provide unprecedented opportunities to identify pathogenic mutations and explore the full natural history of clinically heterogeneous phenotypes such as hearing loss. We noticed a unique audioprofile, characterized by prelingual and rapid deterioration of hearing thresholds at frequencies >0.5 kHz in ...

    journal_title：Human genetics

    pub_type： 杂志文章

    doi：10.1007/s00439-016-1746-7

    authors： Pater JA,Benteau T,Griffin A,Penney C,Stanton SG,Predham S,Kielley B,Squires J,Zhou J,Li Q,Abdelfatah N,O'Rielly DD,Young TL

    更新日期：2017-01-01 00:00:00

  • A genome screen for linkage disequilibrium in HLA-DRB1*15-positive Germans with multiple sclerosis based on 4666 microsatellite markers.

    abstract：:Multiple sclerosis (MS) is a demyelinating disorder of the central nervous system with putative autoimmune aetiology and complex genetic background. Here, we report the results of a genome screen for linkage disequilibrium (LD) by using 6000 microsatellite markers in 198 HLA-DRB1*15-positive MS patients and 198 unrela...

    journal_title：Human genetics

    pub_type： 杂志文章

    doi：10.1007/s00439-002-0801-8

    authors： Goedde R,Sawcer S,Boehringer S,Miterski B,Sindern E,Haupts M,Schimrigk S,Compston A,Epplen JT

    更新日期：2002-09-01 00:00:00

  • Equal proportions of affected cells in muscle and blood of a mosaic carrier of facioscapulohumeral muscular dystrophy.

    abstract：:Autosomal dominant facioscapulohumeral muscular dystrophy (FSHD) is associated with contractions of D4Z4 repeat on 4q35. It displays a remarkable inter- and intra-familial clinical variability ranging from severe phenotype to asymptomatic carriers. Mosaicism for the contracted FSHD-sized allele is a recurrent finding,...

    journal_title：Human genetics

    pub_type： 杂志文章

    doi：10.1007/s00439-005-0100-2

    authors： Tonini MM,Lemmers RJ,Pavanello RC,Cerqueira AM,Frants RR,van der Maarel SM,Zatz M

    更新日期：2006-03-01 00:00:00

  • Identification, mapping, and genomic structure of a novel X-chromosomal human gene (SMPX) encoding a small muscular protein.

    abstract：:Reciprocal probing has been used to identify a cDNA clone (xh8H11) representing a gene preferentially expressed in striated muscle. The gene maps close to DXS7101 31.9 cM from the short arm telomere of the X-chromosome at Xp22.1. On searching expressed and genomic databases, 21 expressed sequence tags were found that ...

    journal_title：Human genetics

    pub_type： 杂志文章

    doi：10.1007/s004390051138

    authors： Patzak D,Zhuchenko O,Lee CC,Wehnert M

    更新日期：1999-11-01 00:00:00

  • Genetic analysis of diabetic nephropathy on chromosome 18 in African Americans: linkage analysis and dense SNP mapping.

    abstract：:Genetic studies in Turkish, Native American, European American, and African American (AA) families have linked chromosome 18q21.1-23 to susceptibility for diabetes-associated nephropathy. In this study, we have carried out fine linkage mapping in the 18q region previously linked to diabetic nephropathy in AAs by genot...

    journal_title：Human genetics

    pub_type： 杂志文章

    doi：10.1007/s00439-009-0732-8

    authors： McDonough CW,Bostrom MA,Lu L,Hicks PJ,Langefeld CD,Divers J,Mychaleckyj JC,Freedman BI,Bowden DW

    更新日期：2009-12-01 00:00:00

  • Analysis of pericentromeric chromosome 21 specific YAC clones by FISH: identification of new markers for molecular-cytogenetic application.

    abstract：:Fluorescence in situ hybridization (FISH) of chromosome 21 specific yeast artificial chromosome (YAC) clones after Alu-PCR (polymerase chain reaction) amplification has been used to find new region-specific DNA probes for the heterochromatic region of chromosome 21. Six overlapping YAC clones from a pericentromeric co...

    journal_title：Human genetics

    pub_type： 杂志文章

    doi：10.1007/BF00225195

    authors： Yurov YB,Laurent AM,Marcais B,Vorsanova SG,Roizes G

    更新日期：1995-03-01 00:00:00