Bone mineral and other bone components in vertebrae evaluated by QCT and MRI.

Abstract:

:To evaluate the usefulness of assessing bone components using magnetic resonance imaging (MRI), the contributions of bone components, including mineral, fat and collagen, to bone mineral density (BMD) and T1 relaxation time (T1) were studied using phantoms. Excised human vertebrae were also evaluated by quantitative computed tomography (QCT) and MRI. T1 was shortened with increasing quantities of fat and collagen. In water, T1 was significantly affected by bone density, while in oil, T1 became slightly longer as bone density increased. The presence of fat and collagen caused under- and overestimations of BMD, respectively. There was good correlation between T1 and BMD in osteoporotic vertebrae and the vertebrae with long T1 showed an increased content of hematopoietic marrow and/or abnormally increased bone mineral. It was concluded that the experimental data showed that MRI can contribute to the assessment of bone quality.

journal_name

Skeletal Radiol

journal_title

Skeletal radiology

authors

Ito M,Hayashi K,Uetani M,Kawahara Y,Ohki M,Yamada M,Kitamori H,Noguchi M,Ito M

doi

10.1007/BF00197987

subject

Has Abstract

pub_date

1993-01-01 00:00:00

pages

109-13

issue

2

eissn

0364-2348

issn

1432-2161

journal_volume

22

pub_type

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