Transcutaneous drug delivery: a practical review.

abstract：:Since 1980, impressive progress in the treatment of solid tumors has altered the practice of pediatric surgical oncology. Because these advances have been balanced by both liberal and conservative viewpoints, an accurate reassessment of traditional approaches has been possible. Noteworthy alterations in chemotherapy, ...

journal_title：Mayo Clinic proceedings

authors： Kaufman BH

更新日期：1986-04-01 00:00:00

abstract：:Two-dimensional echocardiography is useful for the immediate diagnosis of acute myocardial infarction when diagnostic electrocardiographic changes are absent. The technique is also helpful in distinguishing myocardial infarction from other conditions that may clinically or electrocardiographically mimic infarction. Th...

journal_title：Mayo Clinic proceedings

authors： Oh JK,Miller FA,Shub C,Reeder GS,Tajik AJ

更新日期：1987-01-01 00:00:00

abstract：:Genitourinary syndrome of menopause (GSM), previously known as atrophic vaginitis or vulvovaginal atrophy, affects more than half of postmenopausal women. Caused by low estrogen levels after menopause, it results in bothersome symptoms, including vaginal dryness, itching, dyspareunia, urinary urgency and increased fre...

journal_title：Mayo Clinic proceedings

authors： Faubion SS,Sood R,Kapoor E

更新日期：2017-12-01 00:00:00

abstract：:In 51 patients with type 1 and 9 patients with type 2 membranoproliferative glomerulonephritis, we found a male predominance in both types, a wide age range but with younger patients having predominantly type 2 disease, and clinical presentations that varied and included the nephrotic syndrome, an abnormal urinalysis ...

journal_title：Mayo Clinic proceedings

authors： Donadio JV Jr,Slack TK,Holley KE,Ilstrup DM

更新日期：1979-03-01 00:00:00

abstract：:Total respiratory resistance (Rrs) was studied by the forced oscillation technique at a frequency of 3 cps in 76 normal subjects (36 men, 40 women), ages 21 to 64 years. Slopes (equivalent to specific conductance) assuming a linear relationship with zero intercept between 1/Rrs and thoracic gas volume (TGV) were compu...

journal_title：Mayo Clinic proceedings

authors： Jiemsripong K,Hyatt RE,Offord KP

更新日期：1976-09-01 00:00:00

abstract：:The extent of universal screening for gestational diabetes and the incidence of gestational diabetes mellitus (GDM) by diagnosis were analyzed in four primary-care sites. The medical records of 798 women were reviewed to identify the presence of historical risk factors, familial determinants, and biophysical attribute...

journal_title：Mayo Clinic proceedings

authors： Mazze RS,Krogh CL

更新日期：1992-10-01 00:00:00

abstract：OBJECTIVE:To study the esophageal motility of patients with esophageal adenocarcinoma or Barrett esophagus with high-grade dysplasia before and after photodynamic therapy. PATIENTS AND METHODS:In this prospective study conducted between January 1998 and October 1999, esophageal motility testing of the lower esophageal...

journal_title：Mayo Clinic proceedings

authors： Malhi-Chowla N,Wolfsen HC,DeVault KR

更新日期：2001-10-01 00:00:00

abstract：:Prospective data and follow-up information were collected on the initial 200 patients who underwent laparoscopic cholecystectomy at the Mayo Clinic. The operation was completed laparoscopically in all but five patients, who required conversion to laparotomy because of dense scarring or stones in the common bile duct. ...

journal_title：Mayo Clinic proceedings

authors： Donohue JH,Farnell MB,Grant CS,van Heerden JA,Wahlstrom HE,Sarr MG,Weaver AL,Ilstrup DM

更新日期：1992-05-01 00:00:00

abstract：:Autonomic failure and proximal skeletal myopathy are rare features of the Sjögren syndrome (SS). We describe a 51-year-old woman with primary SS who had development of esophageal dysmotility, urinary retention, severe orthostatism, and skeletal myopathy during a 3-month period after the diagnosis of SS. Her symptoms a...

journal_title：Mayo Clinic proceedings

authors： Sorajja P,Poirier MK,Bundrick JB,Matteson EL

更新日期：1999-07-01 00:00:00

abstract：:In recent years, national and regional health education programs have sought to increase public awareness concerning the risks of asymptomatic hypertensive disease. Such programs have fostered community screening and encouraged long-term care. As a result of these intensive educational efforts, larger numbers of perso...

journal_title：Mayo Clinic proceedings

authors： Krishan I

更新日期：1979-12-01 00:00:00

abstract：OBJECTIVE:To report the clinicopathologic findings in patients with Grover's disease. MATERIAL AND METHODS:We reviewed the medical records and biopsy specimens from 72 patients with transient acantholytic dermatosis (Grover's disease) examined at Mayo Clinic Rochester. Hematoxylin-eosin-stained biopsy specimens (from ...

journal_title：Mayo Clinic proceedings

authors： Davis MD,Dinneen AM,Landa N,Gibson LE

更新日期：1999-03-01 00:00:00

abstract：OBJECTIVE:To assess the value of adding remote pointer and dynamic display capabilities to a telemedicine system designed to provide consultative services for patients with congenital heart disease. MATERIAL AND METHODS:Independent observations by the referring physician and the consulting physician provided the data ...

journal_title：Mayo Clinic proceedings

authors： Julsrud PR,Breen JF,Jedeikin R,Peoples W,Wondrow MA,Bailey KR

更新日期：1999-08-01 00:00:00

abstract：:Hypochondriasis (HC), which involves preoccupation with the fear of having a serious illness despite appropriate medical examination, is often encountered in medical settings. The most conspicuous feature of this disorder is seeking excessive reassurance from physicians, medical references, or self-inspection; however...

journal_title：Mayo Clinic proceedings

authors： Abramowitz JS,Schwartz SA,Whiteside SP

更新日期：2002-12-01 00:00:00

abstract：:Mechanical and bioprosthetic mitral prostheses may have many potential complications. In patients with isolated mitral stenosis and a small left ventricular cavity, low-profile prostheses are recommended to avoid myocardial impingement that can result from a high-profile valve and lead to possible left ventricular inf...

journal_title：Mayo Clinic proceedings

authors： Currie PJ,Seward JB,Lam JB,Gersh BJ,Pluth JR

更新日期：1985-03-01 00:00:00

abstract：:B-cell chronic lymphocytic leukemia (B-CLL) is a relatively indolent hematologic malignant disease that, despite a good response to nonaggressive orally administered chemotherapy, currently remains incurable. The overall median duration of survival is more than 5 years, and the presence of anemia or thrombocytopenia a...

journal_title：Mayo Clinic proceedings

authors： Tefferi A,Phyliky RL

更新日期：1992-04-01 00:00:00

abstract：:At the Mayo Clinic from 1962 through 1973, 592 cesarean sections were done among 16,181 deliveries (3.7%); 48% were primary procedures, and 52% were performed because of previous cesarean delivery. Regional anesthesia using epidural block recently has replaced a balanced general anesthesia as the anesthesia of choice...

journal_title：Mayo Clinic proceedings

authors： Aard LA,Saed F

更新日期：1975-07-01 00:00:00

abstract：OBJECTIVE:To assess the effects of glutathione on pain-free walking distance (PFWD) and hemodynamic parameters in patients with peripheral artery disease. PATIENTS AND METHODS:Forty patients with Fontaine stage II peripheral artery disease who were seen between September 2000 and March 2001 at the vascular laboratory ...

journal_title：Mayo Clinic proceedings

authors： Arosio E,De Marchi S,Zannoni M,Prior M,Lechi A

更新日期：2002-08-01 00:00:00

abstract：:Patients with ectatic coronary arteries often have occlusion of the affected arteries. Because ectatic arteries are considered to have medial damage, they are normally assumed to have little capacity to constrict; therefore, spasm has not been considered a factor in the occlusive process. In two patients who had diffu...

journal_title：Mayo Clinic proceedings

authors： Bove AA,Vlietstra RE

更新日期：1985-12-01 00:00:00

abstract：:The Mayo Clinic experience with more than 200 bile acid breath tests was analyzed retrospectively to assess its clinical value. In patients with suspected bacterial overgrowth, the result of the bile acid breath test was compared with that of culture of aspirates of small bowel, and the test was found to have a sensit...

journal_title：Mayo Clinic proceedings

authors： Lauterburg BH,Newcomer AD,Hofmann AF

更新日期：1978-04-01 00:00:00

abstract：:The first 100 liver transplantations at the Mayo Clinic were performed in 83 patients, who required a total of 917 patient days in the intensive-care unit (ICU). The mean duration of stay in the ICU was 5.91 days after liver transplantation and 6.15 days for patients who subsequently required readmission to the ICU. D...

journal_title：Mayo Clinic proceedings

authors： Plevak DJ,Southorn PA,Narr BJ,Peters SG

更新日期：1989-04-01 00:00:00

abstract：OBJECTIVE:To investigate the incidence and risk of adverse clinical outcomes in a "real-world" cohort of patients with atrial fibrillation (AF) anticoagulated with vitamin K antagonists (VKAs) from the Murcia AF Project in comparison with the warfarin arm of the randomized clinical trial (RCT) AMADEUS (Evaluating the U...

journal_title：Mayo Clinic proceedings

authors： Rivera-Caravaca JM,Esteve-Pastor MA,Marín F,Valdés M,Vicente V,Roldán V,Lip GYH

更新日期：2018-08-01 00:00:00

abstract：:Herein we review the symptoms, physical findings, and test results in 131 patients with acoustic neurinoma. The earliest symptoms are unilateral hearing loss, tinnitus, and dysequilibrium. As the disease progresses, facial numbness, facial weakness, and headaches become more prominent. Physical findings other than hea...

journal_title：Mayo Clinic proceedings

authors： Harner SG,Laws ER Jr

更新日期：1983-11-01 00:00:00

abstract：OBJECTIVE:To present a multiyear clinical experience with intravenous bevacizumab for the management of severe gastrointestinal bleeding and/or epistaxis in patients with hereditary hemorrhagic telangiectasia (HHT). PATIENTS AND METHODS:All patients treated with intravenous bevacizumab for severe hereditary hemorrhagi...

journal_title：Mayo Clinic proceedings

authors： Iyer VN,Apala DR,Pannu BS,Kotecha A,Brinjikji W,Leise MD,Kamath PS,Misra S,Begna KH,Cartin-Ceba R,DuBrock HM,Krowka MJ,O'Brien EK,Pruthi RK,Schroeder DR,Swanson KL

更新日期：2018-02-01 00:00:00

abstract：OBJECTIVE:To assess the efficacy and safety of hyperbaric oxygenation (HBO) therapy as adjunctive treatment for diabetic foot ulcers with a systematic review and meta-analysis of the literature. METHODS:MEDLINE, EMBASE, and the Cochrane Library were searched to find relevant articles published up to April 20, 2012, wi...

journal_title：Mayo Clinic proceedings

authors： Liu R,Li L,Yang M,Boden G,Yang G

更新日期：2013-02-01 00:00:00

abstract：:Three case reports in this article illustrate the diagnostic methods used and the treatment course encountered for many patients with diabetic peripheral neuropathic pain (DPNP). Each case addresses an aspect of DPNP: pain that appears to be refractory to initial therapy, DPNP occurring with other medical conditions, ...

journal_title：Mayo Clinic proceedings

authors： Belgrade MJ,Cole BE,McCarberg BH,McLean MJ

更新日期：2006-04-01 00:00:00

abstract：OBJECTIVE:To assess the frequency and significance of GB virus-C infection in type 1 autoimmune hepatitis. MATERIAL AND METHODS:Serum specimens from 94 patients with type 1 autoimmune hepatitis were tested for GB virus-C RNA by reverse transcription and polymerase chain reaction. Serum samples from 50 normal subjects ...

journal_title：Mayo Clinic proceedings

authors： Czaja AJ,Abdulkarim AS,Carpenter HA,Perez RG,Persing DH,Zein NN

更新日期：1998-05-01 00:00:00

abstract：:In this article, we report a case of Leuconostoc bacteremia in a 7-month-old infant who had short-gut syndrome after a gastroschisis repair and who was dependent on total parenteral nutrition through a central venous catheter. The organism was initially misidentified as viridans group streptococcus. Detection of vanco...

journal_title：Mayo Clinic proceedings

authors： Dhodapkar KM,Henry NK

更新日期：1996-12-01 00:00:00

abstract：:Given the burden of cardiovascular disease (CVD), increasing the prevalence of healthy lifestyle choices is a global imperative. Currently, cardiac rehabilitation programs are a primary way that modifiable risk factors are addressed in the secondary prevention setting after a cardiovascular (CV) event/diagnosis. Even ...

journal_title：Mayo Clinic proceedings

authors： Arena R,Guazzi M,Briggs PD,Cahalin LP,Myers J,Kaminsky LA,Forman DE,Cipriano G Jr,Borghi-Silva A,Babu AS,Lavie CJ

更新日期：2013-06-01 00:00:00

abstract：OBJECTIVE:To evaluate, in this before-and-after study, the results of 5 strategies for improving attendance at medical grand rounds at a tertiary care academic medical center. METHODS:The strategies included (1) using electronic card readers to improve understanding of attendance patterns, (2) conducting yearly needs ...

journal_title：Mayo Clinic proceedings

authors： Mueller PS,Litin SC,Sowden ML,Habermann TM,LaRusso NF

更新日期：2003-05-01 00:00:00

abstract：OBJECTIVE:To investigate the association between physical activity (PA) and risk of mortality in a large middle-aged cohort stratified by inflammatory status. PATIENTS AND METHODS:A total of 336,560 individuals (mean age, 39.7 years; 58% male) who underwent comprehensive health screenings were enrolled in this prospec...

journal_title：Mayo Clinic proceedings

authors： Lee JY,Ryu S,Cheong E,Sung KC

更新日期：2016-12-01 00:00:00