Is camptocormia a primary muscular disease?


STUDY DESIGN:This study analyzed computed tomographic scans, magnetic resonance images, and biopsies of the paravertebral muscles of patients with camptocormia and age-matched patients with lumbar interapophyseal osteoarthritis or lumbar vertebral stenosis. OBJECTIVES:To define the muscular lesions and clarify their nature in this particular disorder. SUMMARY OF BACKGROUND DATA:Progressive lumbar kyphosis or camptocormia, a rare disease of the elderly characterized by inability to immobilize the lumbar spine in relation to the pelvis appears to be a result of weakness of the paraspinal muscles. The features presented by these patients do not correspond to any myopathy previously described. METHODS:Twenty-seven patients (5 men and 22 women) mean age 69 years, with camptocormia were compared to fifteen age-matched patients without camptocormia but with posterior interapophyseal osteoarthritis and to nine elderly patients operated for narrowing of lumbar canal. Computed tomographic scans, magnetic resonance images, light microscopy, histochemistry, and electron microscopy of paraspinal muscles were obtained in both groups. RESULTS:In patients with camptocormia, computed tomographic scans and magnetic resonance imaging showed heterogeneous appearance of the spinal muscles with areas of low density. These features were distinct from those of patients with interapophyseal osteoarthritis and were similar to the features described in primary muscular dystrophies. The main microscopic change in camptocormia was the increase of fibrous tissue, frequently with a lobular pattern, not seen in osteoarthritic patients. Familial history of the disorder was frequent (20 out of the 27 patients). CONCLUSION:Camptocormia, disappearing in the recumbent position, is thus very probably linked to muscle involvement. That there is often a family history of such disorder is in favor of a genetically transmitted condition. Magnetic resonance images and computed tomographic scan appearance seems to be in favor of primary muscular disease, restricted to the spinal muscles.


Spine (Phila Pa 1976)




Laroche M,Delisle MB,Aziza R,Lagarrigue J,Mazieres B




Has Abstract


1995-05-01 00:00:00














  • Effect of altering titer, serotype, and promoter in recombinant adenoassociate virus gene therapy expression of spinal cord neurons and astrocytes.

    abstract:STUDY DESIGN:Descriptive histologic analysis of spinal cord gene therapy. OBJECTIVE:To maximize protein expression in rat spinal cord using recombinant adenoassociate virus viral vector. SUMMARY OF BACKGROUND DATA:There are few reports of spinal cord genetic transfer. There have been no reports that compare technique...


    pub_type: 杂志文章


    authors: Harrop JS,Poulsen DJ,Xiao W,Freese A,During MJ

    更新日期:2004-12-15 00:00:00

  • Mobilization of patients after spinal surgery for acute spinal cord injury.

    abstract:STUDY DESIGN:A retrospective review was conducted covering records of patients who underwent spinal surgery after acute spinal cord injury. OBJECTIVE:To study the relation between time of operation and mobilization of patients. SUMMARY OF BACKGROUND DATA:No such report has existed in the literature. METHODS:Reviews ...


    pub_type: 杂志文章


    authors: Wang D,Teddy PJ,Henderson NJ,Shine BS,Gardner BP

    更新日期:2001-10-15 00:00:00

  • Incision of the anulus fibrosus induces nerve root morphologic, vascular, and functional changes. An experimental study.

    abstract:STUDY DESIGN:The effects on nerve root structure, vasculature, and function after incision of the adjacent disc was studied in a dog model. OBJECTIVES:To see if only incision of the disc per se is sufficient for inducing similar changes. SUMMARY OF BACKGROUND DATA:It is well known that nucleus pulposus will induce ne...


    pub_type: 杂志文章


    authors: Kayama S,Konno S,Olmarker K,Yabuki S,Kikuchi S

    更新日期:1996-11-15 00:00:00

  • Spinal chronic subdural hematoma in association with anticoagulant therapy: a case report and literature review.

    abstract:STUDY DESIGN:A case of spinal chronic subdural hematoma (SCSDH) in association with anticoagulant therapy was treated surgically. OBJECTIVE:To clarify the etiopathogenesis, clinical presentation, and surgical outcomes of SCSDH. SUMMARY OF BACKGROUND DATA:Intracranial chronic subdural hematoma is a well-recognized com...


    pub_type: 杂志文章,评审


    authors: Jimbo H,Asamoto S,Mitsuyama T,Hatayama K,Iwasaki Y,Fukui Y

    更新日期:2006-03-15 00:00:00

  • Digital assessment of MRI for lumbar disc desiccation. A comparison of digital versus subjective assessments and digital intensity profiles versus discogram and macroanatomic findings.

    abstract::During magnetic resonance imaging, a vast amount of digital data on anatomic structures is translated into images, which are then assessed subjectively. The development of an objective, sensitive method to directly assess the digital data would have clear benefits, particularly for clinical research on disc degenerati...


    pub_type: 杂志文章


    authors: Videman T,Nummi P,Battié MC,Gill K

    更新日期:1994-01-15 00:00:00

  • Value of immediate preprocedure magnetic resonance imaging in patients scheduled to undergo vertebroplasty or kyphoplasty.

    abstract:STUDY DESIGN:Retrospective case series. OBJECTIVE:To determine the incidence of additional vertebral compression fractures diagnosed with repeat MRI immediately before vertebroplasty or kyphoplasty. SUMMARY OF BACKGROUND DATA:Vertebral compression fractures, which occur frequently in the elderly, are more likely in p...


    pub_type: 杂志文章


    authors: Benz BK,Gemery JM,McIntyre JJ,Eskey CJ

    更新日期:2009-03-15 00:00:00

  • A prospective randomized comparison of 270 degrees fusions to 360 degrees fusions (circumferential fusions).

    abstract:STUDY DESIGN:Prospective randomized comparison of anterior lumbar interbody fusion (ALIF) plus transpedicular instrumentation plus posterolateral fusion (PLF) (360 degrees fusion) to ALIF plus transpedicular instrumentation without PLF (270 degrees fusion). OBJECTIVES:To compare the clinical outcomes, costs, and utili...


    pub_type: 临床试验,杂志文章,随机对照试验


    authors: Schofferman J,Slosar P,Reynolds J,Goldthwaite N,Koestler M

    更新日期:2001-05-15 00:00:00

  • Reduction of severe spondylolisthesis. A preliminary report.

    abstract::This report describes the development of a technique for reduction and fusion of spondylolisthesis that includes posterior mobilization with alartransverse fusion, halo-femoral traction with the patient in some extension, and finally, anterior interbody fusion of the lumbosacral joint. The report emphasizes the techni...


    pub_type: 杂志文章


    authors: McPhee IB,O'Brien JP

    更新日期:1979-09-01 00:00:00

  • A comparative study of pyogenic and tuberculous spondylodiscitis.

    abstract:STUDY DESIGN:We performed a retrospective review of 126 cases of infectious spondylodiscitis over a 4-year period. OBJECTIVE:Differentiation between pyogenic spondylodiscitis (PS) and tuberculous spondylodiscitis (TS) is essential for deciding on the appropriate therapeutic regimen. The aim of this study was to compar...


    pub_type: 杂志文章


    authors: Kim CJ,Song KH,Jeon JH,Park WB,Park SW,Kim HB,Oh MD,Choe KW,Kim NJ

    更新日期:2010-10-01 00:00:00

  • Cost-effectiveness analysis of extended conservative therapy versus surgical intervention in the management of herniated lumbar intervertebral disc.

    abstract::The management of herniated lumbar intervertebral disc for patients not responding to an initial trial of conservative therapy is generally surgical. Little is known about the effect of continued conservative therapy on patients who have not improved or have deteriorated within the first 3 months. This study assessed ...


    pub_type: 杂志文章


    authors: Shvartzman L,Weingarten E,Sherry H,Levin S,Persaud A

    更新日期:1992-02-01 00:00:00

  • Postoperative Trichosporon asahii spondylodiscitis after open lumbar discectomy: a case report.

    abstract:STUDY DESIGN:A case report of Trichosporon asahii spondylodiscitis. OBJECTIVE:To report the first case of T. asahii spondylodiscitis that developed in a healthy woman at the site of an open lumbar discectomy. SUMMARY OF BACKGROUND DATA:Trichosporon is a genus of basidiomycetous yeasts that is common in nature and a m...


    pub_type: 杂志文章


    authors: Kim KW,Ha KY,Kim MS,Choi SM,Lee JS

    更新日期:2008-02-15 00:00:00

  • Relation between adolescent idiopathic scoliosis and morphologic somatotypes.

    abstract:STUDY DESIGN:A prospective and controlled comparative study. OBJECTIVES:To verify the difference in morphologic appearance between a group of adolescents with progressive adolescent idiopathic scoliosis and a control group of normal adolescents. SUMMARY OF BACKGROUND DATA:In a previous retrospective study, the possib...


    pub_type: 杂志文章


    authors: LeBlanc R,Labelle H,Rivard CH,Poitras B

    更新日期:1997-11-01 00:00:00

  • Magnetic Resonance Imaging Safety of Magnetically Controlled Growing Rods in an In Vivo Animal Model.

    abstract:STUDY DESIGN:Experimental animal study. OBJECTIVE:To investigate the interaction between magnetically controlled growing rods (MCGRs) and magnetic resonance imaging (MRI). SUMMARY OF BACKGROUND DATA:Growing rod treatment through serial operations results in adverse effects on the patient and high treatment costs. MCG...


    pub_type: 杂志文章


    authors: Eroglu M,Demirkiran G,Kocyigit IA,Bilgili H,Kaynar MB,Bumin A,Ozcan S,Yazici M

    更新日期:2017-05-01 00:00:00

  • Anatomic consideration of C2 pedicle screw placement.

    abstract:STUDY DESIGN:This anatomic study tested placement of C2 pedicle screws using cadaver specimens. OBJECTIVES:To further assess the safety of transpedicular screw placement in the axis by comparing two surgical techniques. SUMMARY OF BACKGROUND DATA:Transpedicular screw fixation of traumatic spondylolisthesis of the axi...


    pub_type: 杂志文章


    authors: Ebraheim N,Rollins JR Jr,Xu R,Jackson WT

    更新日期:1996-03-15 00:00:00

  • The effect of anterior-posterior shear on the wear of CHARITÉ total disc replacement.

    abstract:STUDY DESIGN:An in vitro study of the wear rates of the CHARITÉ lumbar total disc replacement (TDR). OBJECTIVE:To investigate the effect of anterior-posterior shear on the in vitro wear rates of the CHARITÉ lumbar TDR. SUMMARY OF BACKGROUND DATA:Current standards prescribe only 4-degrees of freedom (DOF) inputs for e...


    pub_type: 杂志文章


    authors: Vicars R,Prokopovich P,Brown TD,Tipper JL,Ingham E,Fisher J,Hall RM

    更新日期:2012-04-20 00:00:00

  • Laboratory testing of segmental spinal instrumentation versus traditional Harrington instrumentation for scoliosis treatment.

    abstract::The authors have tested 51 instrumented calf spines in vitro, using a scoliosis simulator, to evaluate the adequacy of fixation and nature of acute failure seen with various methods of scoliosis instrumentation. Tests were performed in compressive loading, rotation, and forward bending on the following instrumentation...


    pub_type: 杂志文章


    authors: Wenger DR,Carollo JJ,Wilkerson JA Jr,Wauters K,Herring JA

    更新日期:1982-05-01 00:00:00

  • Rib deformities in congenital scoliosis.

    abstract:STUDY DESIGN:Retrospective review. OBJECTIVE:To identify the incidence and characteristics of rib anomalies in patients with congenital scoliosis (CS) in a Chinese population. SUMMARY OF BACKGROUND DATA:Rib deformities and intraspinal anomalies often coexist in individuals with CS. Rib deformities may assist in diagn...


    pub_type: 杂志文章


    authors: Xue X,Shen J,Zhang J,Zhao H,Li S,Zhao Y,Liang J,Qiu G,Weng X

    更新日期:2013-12-15 00:00:00

  • Regenerative Intervertebral Disc Endplate Based on Biomimetic Three-dimensional Scaffolds.

    abstract:STUDY DESIGN:Fabrication and characterization of a regenerative intervertebral disc (IVD) cartilaginous endplate (CEP) based on tissue culturing on biomimetic scaffolds. OBJECTIVE:To fabricate a regenerative CEP to support nutrients and metabolites exchange between IVD and the milieu interior. SUMMARY OF BACKGROUND D...


    pub_type: 杂志文章


    authors: Yuan D,Chen Z,Zhou Y,Xiao D,Liu K,Xiang X,Deng L,Dong H,Feng G

    更新日期:2017-03-01 00:00:00

  • Risk Factors of Adjacent Segment Disease After Transforaminal Inter-Body Fusion for Degenerative Lumbar Disease.

    abstract:STUDY DESIGN:A retrospective study. OBJECTIVE:The purpose of this study was to determine the incidence and risk factors of adjacent segment disease (ASD) after transforaminal inter-body fusion (TLIF) for degenerative lumbar disease. SUMMARY OF BACKGROUND DATA:ASD is a major complication after spinal fusion. Many repo...


    pub_type: 杂志文章


    authors: Yamasaki K,Hoshino M,Omori K,Igarashi H,Nemoto Y,Tsuruta T,Matsumoto K,Iriuchishima T,Ajiro Y,Matsuzaki H

    更新日期:2017-01-15 00:00:00

  • Depression is associated with a poorer outcome of lumbar spinal stenosis surgery: a two-year prospective follow-up study.

    abstract:STUDY DESIGN:Prospective clinical study. OBJECTIVE:To investigate the effect of depressive symptoms on the surgery outcome on 2-year follow-up among lumbar spinal stenosis (LSS) patients. SUMMARY OF BACKGROUND DATA:Previous research has suggested an association between preoperative depressive symptoms and a poorer su...


    pub_type: 杂志文章


    authors: Sinikallio S,Aalto T,Airaksinen O,Lehto SM,Kröger H,Viinamäki H

    更新日期:2011-04-15 00:00:00

  • Immunohistologic study of the ruptured intervertebral disc of the lumbar spine.

    abstract:STUDY DESIGN:This study analyzed immunohistological features of the extruded or sequestrated intervertebral disc of the lumbar spine. To clarify the pathogenesis of neovascularization, cells isolated from herniated disc were cultured and examined biologically. OBJECTIVES:The objectives of this study were to characteri...


    pub_type: 杂志文章


    authors: Doita M,Kanatani T,Harada T,Mizuno K

    更新日期:1996-01-15 00:00:00

  • Preoperative MRI analysis of patients with idiopathic scoliosis: a prospective study.

    abstract:STUDY DESIGN:A prospective trial of preoperative MRI study in patients with "idiopathic" scoliosis. OBJECTIVES:To investigate the prevalence of neural axis malformations and the clinical relevance of MRI in the evaluation of patients with idiopathic scoliosis undergoing surgical intervention. SUMMARY OF BACKGROUND DA...


    pub_type: 杂志文章


    authors: Inoue M,Minami S,Nakata Y,Otsuka Y,Takaso M,Kitahara H,Tokunaga M,Isobe K,Moriya H

    更新日期:2005-01-01 00:00:00

  • Magnetic resonance imaging findings in relation to the COL9A2 tryptophan allele among patients with sciatica.

    abstract:STUDY DESIGN:The phenotype of patients with sciatica who have the Trp2 allele is characterized cross-sectionally. OBJECTIVE:To determine whether it is possible to differentiate patients with the Trp2 allele clinically or by magnetic resonance imaging. SUMMARY OF BACKGROUND DATA:Several studies have indicated a positi...


    pub_type: 杂志文章


    authors: Karppinen J,Pääkkö E,Räinä S,Tervonen O,Kurunlahti M,Nieminen P,Ala-Kokko L,Malmivaara A,Vanharanta H

    更新日期:2002-01-01 00:00:00

  • National and regional rates and variation of cervical discectomy with and without anterior fusion, 1990-1999.

    abstract:STUDY DESIGN:A national hospitalization database was used to determine rates and trends in the treatment of cervical disc disease. OBJECTIVE:To examine the temporal and geographic variations in hospitalizations and surgical procedures for cervical disc disease. SUMMARY OF BACKGROUND DATA:Studies of spinal surgery dur...


    pub_type: 杂志文章


    authors: Angevine PD,Arons RR,McCormick PC

    更新日期:2003-05-01 00:00:00

  • Urgent surgical decompression compared to methylprednisolone for the treatment of acute spinal cord injury: a randomized prospective study in beagle dogs.

    abstract:STUDY DESIGN:Experimental dog model of acute spinal cord injury. OBJECTIVE:To compare the relative value of methylprednisolone, surgical decompression, or both for the treatment of traumatic spinal cord injury. SUMMARY OF BACKGROUND DATA:Acute spinal cord injury results from both primary damage to the spinal cord at ...


    pub_type: 杂志文章,随机对照试验


    authors: Rabinowitz RS,Eck JC,Harper CM Jr,Larson DR,Jimenez MA,Parisi JE,Friedman JA,Yaszemski MJ,Currier BL

    更新日期:2008-10-01 00:00:00

  • Cervical pedicle screws: conventional versus computer-assisted placement of cannulated screws.

    abstract:STUDY DESIGN:Prospective clinical study with postoperative radiologic control of pedicle screw placement in the cervical spine. OBJECTIVES:To evaluate whether cervical pedicle screws can be placed safely in a conventional technique when using cannulated screws and separate stab incisions. Also, to evaluate if accuracy...


    pub_type: 杂志文章


    authors: Richter M,Cakir B,Schmidt R

    更新日期:2005-10-15 00:00:00

  • Using tissue expanders in spinal surgery for deficient soft tissue or postirradiation cases.

    abstract::Prior irradiation and scarring can complicate wound closure following spinal surgery. Implanted tissue expanders were used six times in four patients to aid skin closure. Three patients had prior irradiation for cancer, and one had myelomeningocele. The average interval between placement and removal of the expanders w...


    pub_type: 杂志文章


    authors: Paonessa KJ,Zide B,Errico T,Engler GL

    更新日期:1991-08-01 00:00:00

  • Long-term follow-up of lower lumbar fusion patients.

    abstract::To determine the long-term effects of lower lumbar fusion, 94 subjects were catalogued from medical records. They had a lumbar arthrodesis at the third lumbar level or below and their operations were performed before 1964. Twenty-four were not located and 8 were deceased. Sixty-two subjects (72% of available sample) c...


    pub_type: 杂志文章


    authors: Lehmann TR,Spratt KF,Tozzi JE,Weinstein JN,Reinarz SJ,el-Khoury GY,Colby H

    更新日期:1987-03-01 00:00:00

  • Comparison between the outer table and intracortical methods of obtaining autogenous bone graft from the iliac crest.

    abstract:STUDY DESIGN:A prospective study in two groups of patients selected randomly. OBJECTIVES:To determine whether keeping the outer and inner cortices of the ilium intact, while obtaining bone graft, would result in reduced postoperative bleeding and less postoperative pain. SUMMARY OF BACKGROUND DATA:Donor site complica...


    pub_type: 临床试验,杂志文章,随机对照试验


    authors: Mirovsky Y,Neuwirth MG

    更新日期:2000-07-01 00:00:00

  • Comparing the fixation of a novel hollow screw versus a conventional solid screw in human sacra under cyclic loading.

    abstract:STUDY DESIGN:The loosening rates of two monocortical pedicle screw designs (hollow and solid) were compared in a cadaveric sacrum model subjected to cyclic loading. OBJECTIVE:To determine if a hollow screw would be more resistant to loosening than a solid pedicle screw when placed into the pedicles of S1 and tested un...


    pub_type: 杂志文章


    authors: McLachlin SD,Beaton BJ,Sabo MT,Gurr KR,Bailey SI,Bailey CS,Dunning CE

    更新日期:2008-08-01 00:00:00