Study of some biochemical changes among workers occupationally exposed to phenol, alone or in combination with other organic solvents.

Abstract:

:The present study was aimed for the effects of exposure to multiple organic solvent vapors in comparison with single exposure to phenol. It included 20 workers exposed to phenol alone and 32 workers of combined exposure to phenol, benzene, toluene and methyl ethyl ketone. A control group of 30 subjects was also included. The levels of transaminases, total proteins, prothrombin time, bleeding time, clotting time, fasting blood sugar, serum creatinine and some trace elements (copper, zinc, iron, magnesium, manganese and calcium) were determined in blood together with a complete blood picture. Urine samples were analyzed for phenol, hippuric acid and methyl ethyl ketone. The effects of combined exposure did not differ from that of exposure to phenol alone concerning the majority of the tested parameters. Only the levels of platelets count, prothrombin time, eosinophils, copper and iron have been affected by combined exposure in a probably additive manner.

journal_name

Ind Health

journal_title

Industrial health

authors

Shamy MY,el Gazzar RM,el Sayed MA,Attia AM

doi

10.2486/indhealth.32.207

subject

Has Abstract

pub_date

1994-01-01 00:00:00

pages

207-14

issue

4

eissn

0019-8366

issn

1880-8026

journal_volume

32

pub_type

临床试验,杂志文章,随机对照试验
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