Abstract:
:Two siblings with the "happy puppet" syndrome are presented. Their clinical features are quite similar and closely resemble those of previously reported cases. These features include severe mental retardation, epileptic seizures, easily provoked and prolonged paroxysms of laughter, atactic jerky movements, hypotonia, large mandible with prognathia, and 2-3 cps spike and wave activity in the EEG. The occurrence of this syndrome in the two siblings suggests a genetic etiology possible as an autosomal recessive trait.
journal_name
Hum Genetjournal_title
Human geneticsauthors
Kuroki Y,Matsui I,Yamamoto Y,Ieshima Adoi
10.1007/BF00295701subject
Has Abstractpub_date
1980-01-01 00:00:00pages
227-9issue
2eissn
0340-6717issn
1432-1203journal_volume
56pub_type
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