An academic department of anaesthesia in a new Canadian medical school.

abstract：:In this study we investigated in vitro and in vivo effects of propofol in malignant hyperthermia susceptible (MHS) patients in order to assess the safety of propofol infusion as a non-triggering anaesthetic technique for diagnostic and therapeutic procedures. In vitro, human MHS muscle samples were exposed to propofol...

journal_title：Anaesthesia and intensive care

authors： McKenzie AJ,Couchman KG,Pollock N

更新日期：1992-05-01 00:00:00

abstract：:We have previously shown that a model of anaesthetic uptake and distribution, developed for use as a teaching tool, is able to predict end-tidal isoflurane and sevoflurane concentrations at least as well as commonly used propofol models predict blood levels of propofol. Models with good predictive performance may be u...

journal_title：Anaesthesia and intensive care

authors： Kennedy R

更新日期：2006-04-01 00:00:00

abstract：:The Competency-Based Training program in Intensive Care Medicine in Europe identified 12 competency domains. Professionalism was given a prominence equal to technical ability. However, little information pertaining to fellows' views on professionalism is available. A nationwide qualitative study was performed. The mod...

journal_title：Anaesthesia and intensive care

authors： van Mook WN,De Grave WS,Gorter SL,Zwaveling JH,Schuwirth LW,van der Vleuten PM

更新日期：2011-01-01 00:00:00

abstract：:Patient acceptance is a particularly relevant method of assessing currently employed epidural and intravenous techniques of opioid analgesia after elective caesarean section. We have prospectively studied 71 such patients, randomised postoperatively to receive epidural morphine, intravenous morphine or intravenous pet...

journal_title：Anaesthesia and intensive care

authors： Cade L,Ashley J,Ross AW

更新日期：1992-02-01 00:00:00

abstract：:Vancomycin is a commonly used antibiotic due to the high burden of methicillin-resistant Staphylococcus aureus infections. This study aimed to describe the pharmacokinetics (PK) of vancomycin in Australian Indigenous patients with severe sepsis, and advise an optimal dosing strategy. A population PK study was c...

journal_title：Anaesthesia and intensive care

authors： Tsai D,Stewart PC,Hewagama S,Krishnaswamy S,Wallis SC,Lipman J,Roberts JA

更新日期：2018-07-01 00:00:00

abstract：:We carried out an audit of needle cricothyroidotomy and transtracheal ventilation used during anaesthesia for elective endolaryngeal surgery. The data on 90 consecutive procedures was collected over two years. Patients were anaesthetized using a total intravenous technique. An intravenous cannula or Tuohy needle was p...

journal_title：Anaesthesia and intensive care

authors： Russell WC,Maguire AM,Jones GW

更新日期：2000-02-01 00:00:00

abstract：:We present a case of acute lithium intoxication in a 51-year-old woman on chronic lithium therapy. Her serum lithium level was 10.6 mmol/l 13 hours after ingestion and 5.8 mmol/l at 24 hours. Dialysis therapy was not employed and she recovered well after fluid resuscitation. Serum lithium levels in chronic intoxicatio...

journal_title：Anaesthesia and intensive care

authors： Nagappan R,Parkin WG,Holdsworth SR

更新日期：2002-02-01 00:00:00

abstract：:Cerebral perfusion was evaluated in twelve patients undergoing elective infra-renal abdominal aortic aneurysmectomy by transcranial Doppler ultrasonography-determined middle cerebral artery mean flow velocity, near-infrared spectroscopy-assessed cerebral oxygen saturation and systemic haemodynamic variables. The middl...

journal_title：Anaesthesia and intensive care

authors： Liu G,Burcev I,Pott F,Ide K,Horn A,Secher NH

更新日期：1999-04-01 00:00:00

abstract：:A study was undertaken to determine the time constants of elimination and effect compartment equilibration of suxamethonium and for the slope exponent of the Hill equation. Twelve patients were anaesthetized with thiopentone, fentanyl, and isoflurane in nitrous oxide and oxygen. After allowing conditions to become sta...

journal_title：Anaesthesia and intensive care

authors： Torda TA,Graham GG,Warwick NR,Donohue P

更新日期：1997-06-01 00:00:00

abstract：:Purpura fulminans is a rare but devastating haemorrhagic condition often associated with sepsis. Many different organisms have been implicated in the aetiology of purpura fulminans, most commonly Neisseria meningitidis and Streptococcus pneumoniae. We report a case of purpura fulminans associated with Lactobacillus pa...

journal_title：Anaesthesia and intensive care

authors： Burns D,Hurst JR,Hopkins S,Patch D,Burroughs AK,Agarwal B

更新日期：2007-02-01 00:00:00

abstract：:The effects of halothane (0.5-2%) and enflurane (1-4%) on two Transoxode transcutaneous oxygen (TcPO2) electrodes (Hellige Servomed Oxymonitor SM.361 system) were serially tested in atmospheres of nitrogen, air and 50% nitrous oxide in oxygen. Both TcPO2 electrodes reduced and "read" halothane but no enflurane. Calibr...

journal_title：Anaesthesia and intensive care

authors： Downing JW,Mankowitz M,Brock-Utne JG,Holloway AM

更新日期：1981-05-01 00:00:00

abstract：:Acute lung injury/acute respiratory distress syndrome (ALI / ARDS) is the most serious pulmonary complication after lung resection. This study investigated the incidence and outcome of patients with ALI / ARDS who required mechanical ventilation within one week of undergoing pneumonectomy for primary lung cancer and a...

journal_title：Anaesthesia and intensive care

authors： Jeon K,Yoon JW,Suh GY,Kim J,Kim K,Yang M,Kim H,Kwon OJ,Shim YM

更新日期：2009-01-01 00:00:00

abstract：:The cerebral and systemic kinetics of intravenous thiopentone (250 mg over 2 minutes, n=5) and propofol (100 mg over 2 minutes, n=6) were determined in sheep anaesthetized with halothane (2.0%) and mechanically ventilated to an end-expired carbon dioxide tension of 40 mmHg. The sheep were previously instrumented with ...

journal_title：Anaesthesia and intensive care

authors： Upton RN,Ludbrook GL,Grant C

更新日期：2001-04-01 00:00:00

abstract：:Myasthenia gravis, a rare disease in children, occurs in a variety of forms. The aetiology and clinical presentations are reviewed. Eight patients who were studied with electromyography are presented. The results show that, in general, patients with the usual pattern of disease are resistant to suxamethonium (ED95 3-4...

journal_title：Anaesthesia and intensive care

authors： Brown TC,Gebert R,Meretoja OA,Shield LK

更新日期：1990-11-01 00:00:00

abstract：:A technique of subclavian vein catheterization is described, tailored to the individual patient, to reduce the risk of right atrial placement with central venous catheter (CVC) insertion. Using data gathered retrospectively for Quality Improvement purposes, CVC tip location was assessed. The standard technique used in...

journal_title：Anaesthesia and intensive care

authors： Chalkiadis GA,Goucke CR

更新日期：1998-02-01 00:00:00

abstract：:Self-assessment and audit in anaesthesia require a systematic approach to postoperative data collection. The increasing prevalence of mobile internet technology offers a new data collection method for anaesthetists. In this paper, a system for mobile internet data collection is described and the preliminary experience...

journal_title：Anaesthesia and intensive care

authors： Belavy D

更新日期：2014-11-01 00:00:00

abstract：:Monoclonal antibodies (mAb) have revolutionised many areas of medicine, particularly research and diagnostics. Murine, human and humanized mAb have all been developed. The most important clinical applications to date have been in the fields of transplantation and oncology. Experimental and limited clinical trials sugg...

journal_title：Anaesthesia and intensive care

authors： Peake S

更新日期：1993-12-01 00:00:00

abstract：:Unselected preoperative coagulation testing is known to have low positive yield. However, no study has specifically evaluated neurosurgical patients. A retrospective study of 1211 patients having neurosurgery over a one-year period was therefore conducted. Preoperative test results (activated partial thromboplastin ti...

journal_title：Anaesthesia and intensive care

authors： Schramm B,Leslie K,Myles PS,Hogan CJ

更新日期：2001-08-01 00:00:00

abstract：:There have been several reports of propofol becoming extrinsically contaminated with bacteria. These reports have usually related to infusions or delays in administration after the ampoule has been opened. This observational study was performed to examine bacterial contamination of propofol during usual practice in th...

journal_title：Anaesthesia and intensive care

authors： Soong WA

更新日期：1999-10-01 00:00:00

abstract：:This study confirms that distance to the epidural space from the skin at the L3-4 interspace is only moderately correlated with body mass index in obstetric patients. A similar moderate linear correlation was found in the non-obstetric patients. However, in obese patients (BMI > 25), distance to epidural space from th...

journal_title：Anaesthesia and intensive care

authors： Watts RW

更新日期：1993-06-01 00:00:00

abstract：:The aim of this study was to determine the extent of unnecessary investigation performed as part of the preoperative preparation of elective surgical patients in a teaching hospital and to audit the effect of guidelines and education designed to reduce unnecessary investigation. Guidelines were developed for preoperat...

journal_title：Anaesthesia and intensive care

authors： Greer AE,Irwin MG

更新日期：2002-06-01 00:00:00

abstract：:The potential transmission of disease by anaesthetic and ventilator breathing circuits has resulted in the widespread use of filters. Convincing scientific evidence of their complete efficacy is lacking particularly in regard to viruses. In the past, practical difficulties precluded the use of new or autoclavable equi...

journal_title：Anaesthesia and intensive care

authors： Komesaroff D

更新日期：1996-04-01 00:00:00

abstract：:The ultrasound software package Enhanced Needle Visualization (ENV) has been reported to provide improved ultrasound imaging of needles even at steep insertion angles. ENV has three settings: shallow, medium and steep. However, the angles are unknown. We examined the advantages and indications of ENV in an in vitro st...

journal_title：Anaesthesia and intensive care

authors： Takatani J,Takeshima N,Okuda K,Uchino T,Hagiwara S,Noguchi T

更新日期：2012-09-01 00:00:00

abstract：:We report three cases of anaphylaxis during anaesthesia confirmed on intradermal testing to be related to patent blue V dye (Guerbet - Chemical Abstract Service 3536-49-0). All three cases were associated with moderate to severe hypotension. Two cases had delayed onset, and two were associated with a rash. None of the...

journal_title：Anaesthesia and intensive care

authors： Howard JD,Moo V,Sivalingam P

更新日期：2011-03-01 00:00:00

abstract：:The ability of cricoid pressure to prevent inflation of the stomach during mask ventilation of a patient was studied. Fifty patients were randomly allocated to either have or not have cricoid pressure applied during a three-minute period of standardised mask ventilation. Patients who had had cricoid pressure applied h...

journal_title：Anaesthesia and intensive care

authors： Petito SP,Russell WJ

更新日期：1988-05-01 00:00:00

abstract：:A computer-based data storage and analysis system has been used to examine data obtained from 1257 patients admitted to an intensive care unit. The system readily provides administrative and clinical information which can be used to assess the workload, therapeutic efficiency and cost-effectiveness of such a unit. As ...

journal_title：Anaesthesia and intensive care

authors： Pybus DA,Gatt S,Torda TA

更新日期：1982-08-01 00:00:00

abstract：:The concept of a Medical Emergency Team was developed in order to rapidly identify and manage seriously ill patients at risk of cardiopulmonary arrest and other high-risk conditions. The aim of this study was to describe the utilization and outcome of Medical Emergency Team interventions over a one-year period at a te...

journal_title：Anaesthesia and intensive care

authors： Lee A,Bishop G,Hillman KM,Daffurn K

更新日期：1995-04-01 00:00:00

abstract：:Breathing through an endotracheal tube, connector, and ventilator demand valve imposes an added load on the respiratory muscles. As respiratory muscle fatigue is thought to be a frequent cause of ventilator dependence, we sought to examine the efficacy of five different ventilators in reducing this imposed work throug...

journal_title：Anaesthesia and intensive care

authors： Bersten AD,Rutten AJ,Vedig AE

更新日期：1993-02-01 00:00:00

abstract：:Unilateral or bilateral raised hemidiaphragms were observed on chest X-ray in three patients with severe tetanus. Diaphragmatic movement was absent on ultrasonography and fluoroscopy. Nerve conduction study confirmed phrenic nerve palsy. Bilateral involvement caused delayed weaning from the ventilator, whereas unilate...

journal_title：Anaesthesia and intensive care

authors： Panda NB,Yaddanapudi S,Bharadwaj N,Das C,Chari P

更新日期：2004-04-01 00:00:00

abstract：:Optimising perioperative haemodynamic status may reduce postoperative complications. In this prospective prevalence study, we investigated the associations between standard haemodynamic parameters and a low central venous oxygen saturation (ScvO2) in patients after major surgery. A total of 201 patients requiring cont...

journal_title：Anaesthesia and intensive care

authors： Litton E,Silbert B,Ho KM

更新日期：2015-01-01 00:00:00