Abstract:
:We describe an interactive computer program (ANALYSEQ) that is used from a simple graphics terminal. The main purpose of the program is to determine the function of nucleic acid sequences but it also offers the simpler listing, searching and counting options. It contains methods to locate genes by looking for the effects that coding for a protein has on the coding sequence, to locate tRNA genes by looking for secondary structure and conserved bases, and methods to locate signals such as promoters. Techniques to identify unusual regions of sequence and to search for potential Z DNA-forming regions are also included. Most of the routines produce graphical output which gives ease of interpretation and allows superposition of several independent forms of analysis.
journal_name
Nucleic Acids Resjournal_title
Nucleic acids researchauthors
Staden Rdoi
10.1093/nar/12.1part2.521subject
Has Abstractpub_date
1984-01-11 00:00:00pages
521-38issue
1 Pt 2eissn
0305-1048issn
1362-4962journal_volume
12pub_type
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journal_title:Nucleic acids research
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更新日期:2018-09-06 00:00:00
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journal_title:Nucleic acids research
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journal_title:Nucleic acids research
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journal_title:Nucleic acids research
pub_type: 杂志文章
doi:10.1093/nar/gkm149
更新日期:2007-01-01 00:00:00
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journal_title:Nucleic acids research
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journal_title:Nucleic acids research
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更新日期:2021-01-06 00:00:00
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journal_title:Nucleic acids research
pub_type: 杂志文章
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更新日期:2018-04-20 00:00:00
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journal_title:Nucleic acids research
pub_type: 杂志文章
doi:10.1093/nar/17.15.6087
更新日期:1989-08-11 00:00:00
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journal_title:Nucleic acids research
pub_type: 杂志文章
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更新日期:1982-11-25 00:00:00
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journal_title:Nucleic acids research
pub_type: 杂志文章
doi:10.1093/nar/gkl689
更新日期:2006-01-01 00:00:00
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journal_title:Nucleic acids research
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journal_title:Nucleic acids research
pub_type: 杂志文章
doi:10.1093/nar/gkg374
更新日期:2003-05-15 00:00:00
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journal_title:Nucleic acids research
pub_type: 杂志文章
doi:10.1093/nar/gkf647
更新日期:2002-12-01 00:00:00
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journal_title:Nucleic acids research
pub_type: 杂志文章
doi:10.1093/nar/10.9.2951
更新日期:1982-05-11 00:00:00
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journal_title:Nucleic acids research
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journal_title:Nucleic acids research
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journal_title:Nucleic acids research
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更新日期:2020-10-09 00:00:00
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journal_title:Nucleic acids research
pub_type: 杂志文章
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更新日期:2003-03-15 00:00:00
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journal_title:Nucleic acids research
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更新日期:2010-09-01 00:00:00
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journal_title:Nucleic acids research
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abstract::KRAS is one of the most mutated genes in human cancer. It is controlled by a G4 motif located upstream of the transcription start site. In this paper, we demonstrate that 8-oxoguanine (8-oxoG), being more abundant in G4 than in non-G4 regions, is a new player in the regulation of this oncogene. We designed oligonucleo...
journal_title:Nucleic acids research
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更新日期:2018-01-25 00:00:00
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journal_title:Nucleic acids research
pub_type: 杂志文章
doi:10.1093/nar/gkf423
更新日期:2002-07-15 00:00:00
abstract::In this study, we present the DNA-Binding Site Identifier (DBSI), a new structure-based method for predicting protein interaction sites for DNA binding. DBSI was trained and validated on a data set of 263 proteins (TRAIN-263), tested on an independent set of protein-DNA complexes (TEST-206) and data sets of 29 unbound...
journal_title:Nucleic acids research
pub_type: 杂志文章
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更新日期:2013-09-01 00:00:00