Neuropsychological impairment with schizophrenia vs. acute and chronic cerebral lesions.

Abstract:

:Performed detailed neuropsychological evaluations with 25 recently hospitalized schizophrenics in whom systematic neurologic workups had failed to reveal CNS disease. Efforts were made to minimize possible effects of drug-induced extrapyramidal symptoms on test performance. Although the schizophrenics showed some neuropsychological impairment relative to 25 normals, their deficits were not as severe as those of patients known to have either acute or chronic brain disorders (N = 25). The diagnostic accuracy achieved by the tests supports their use in short-term treatment facilities when the differential diagnosis includes schizophrenia and brain disorder, especially acute brain disorder. Schizophrenics' neuropsychological impairment was more correlated with degree of EEG abnormality than with degree of psychosis, which suggests a possible organic basis for the deficits that they showed on testing.

journal_name

J Clin Psychol

authors

Heaton RK,Vogt AT,Hoehn MM,Lewis JA,Crowley TJ,Stallings MA

doi

10.1002/1097-4679(197901)35:1<46::aid-jclp22703501

subject

Has Abstract

pub_date

1979-01-01 00:00:00

pages

46-53

issue

1

eissn

0021-9762

issn

1097-4679

journal_volume

35

pub_type

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