Abstract：
BACKGROUND:To formulate clinical pathways for identifying clinically significant prostate cancer (csPC) and avoiding insignificant prostate cancer (isPC) in those without suspicious regions of interest on multi-parametric magnetic resonance imaging (mpMRI) of the prostate. METHODS:A retrospective review identified patients with negative mpMRI who underwent subsequent transperineal prostate biopsy across two centres. Patient characteristics and association with biopsy results were evaluated using univariate and multivariate regression analyses. RESULTS:A total of 144 patients were identified as having negative mpMRI and undergoing subsequent transperineal prostate biopsy; 18% (25/144) of the cohort were found to have csPC. Logistic regression analysis failed to identify statistically significant predictive factors. In this cohort, if all patients with prostate-specific antigen > 3.0 were biopsied the least amount of csPC is missed, at 20% (5/25) however all isPC would be diagnosed. The least amount of isPC is diagnosed with a biopsy threshold of >15% from the European Randomized Study of Screening for Prostate Cancer calculator with 20% (5/25) of isPC diagnoses made however only 10.5% (2/19) csPC would be diagnosed. A biopsy threshold of >5% risk reduces the number of csPC missed to 37% (7/19) however increases isPC diagnoses to 54% (13/24) of the population. CONCLUSION:False-negative rates of prostate MRI for csPC are significant within our cohort at 18%. The decision to biopsy should be made in conjunction with a risk profile acceptable by the patient and clinician. The current study demonstrates that there is a need to balance the risk of missing csPC and harm of diagnosing isPC.
journal_name
ANZ J Surgjournal_title
ANZ journal of surgeryauthors
Doan P,Lahoud J,Kim L,Patel MIdoi
10.1111/ans.16583subject
Has Abstractpub_date
2021-01-21 00:00:00eissn
1445-1433issn
1445-2197pub_type
杂志文章abstract：BACKGROUND:Atrial fibrillation (AF) after coronary artery bypass graft surgery constitutes the most common sustained arrhythmia and results in many complications. The purpose of this study was to assess the effects of prophylactic use of beta-blockers against atrial fibrillation in off-pump surgery patients in the earl...
journal_title：ANZ journal of surgery
pub_type： 临床试验,杂志文章
doi：10.1111/j.1445-2197.2007.04088.x
更新日期：2007-06-01 00:00:00
abstract：:Abraham Colles had the good fortune to describe the most common fracture about the wrist but, because its description was published in a provincial journal, it received little attention and was almost never referred to in his lifetime. The same can be said of Claude Pouteau who described the same fracture in another l...
journal_title：ANZ journal of surgery
pub_type： 历史文章,杂志文章
doi：10.1111/j.1445-2197.2005.03414.x
更新日期：2005-05-01 00:00:00
abstract：BACKGROUND:Trauma teams have been associated with improved survival probability of paediatric trauma patients. The present study seeks to estimate the use of trauma teams in Australian paediatric tertiary referral centres and describe their medical composition, leadership and criteria for activation. METHODS:Australia...
journal_title：ANZ journal of surgery
pub_type： 杂志文章
doi：10.1111/j.1445-1433.2004.03213.x
更新日期：2004-11-01 00:00:00
abstract：BACKGROUND:The purpose of this study was to clarify the post-operative prognosis of pancreatic head cancer with pathologic portal vein (PV) or superior mesenteric vein (SMV) invasion. METHODS:From May 1995 to December 2009, preoperative, intra-operative and post-operative data from 276 patients who underwent pancreati...
journal_title：ANZ journal of surgery
pub_type： 杂志文章
doi：10.1111/ans.12502
更新日期：2015-04-01 00:00:00
abstract：BACKGROUND:The education and training of tomorrow’s surgeons are predicated upon the involvement of a broad spectrum of surgical educators. Identification of the factors that influence their ongoing participation is crucial for its continuity. METHODS:A study was performed on 695 surgeons identified as having major in...
journal_title：ANZ journal of surgery
pub_type： 杂志文章
doi：10.1111/j.1445-2197.2011.05777.x
更新日期：2011-06-01 00:00:00
abstract：:Abdominal wound dehiscence is a surgical catastrophe that can be attributed to patients or technical factors. The technical properties of the monofilament sutures and knots that are commonly used in abdominal closure are poorly understood. The aim of this study was to compare the tensile strength of monofilament sutur...
journal_title：ANZ journal of surgery
pub_type： 杂志文章
doi：10.1111/j.1445-2197.2007.04394.x
更新日期：2008-03-01 00:00:00
abstract：BACKGROUND:We aimed to document the anatomical variations of pulmonary fissures found during routine forensic autopsies. METHODS:A total of 256 pairs of lungs were investigated. Presence of any variant and accessory fissures was noted. RESULTS:Seventy-seven percent of the lungs had anatomical variations. In about 2/3...
journal_title：ANZ journal of surgery
pub_type： 杂志文章
doi：10.1111/ans.15553
更新日期：2020-04-01 00:00:00
abstract：BACKGROUND:This study was a retrospective analysis of patients who underwent minor or major duct surgery for pathological nipple discharge. The results of clinical examination, mammography, ultrasonography and cytodiagnosis of the nipple discharge were studied in order to predict those patients at risk of underlying or...
journal_title：ANZ journal of surgery
pub_type： 杂志文章
doi：10.1111/j.1445-2197.2010.05270.x
更新日期：2010-09-01 00:00:00
abstract：BACKGROUND:The purpose of the present paper is to introduce a new surgical procedure using the external oblique aponeurosis (EOA) for repair of spontaneous renal allograft rupture. METHODS:Thirty-eight cases with spontaneous renal allograft rupture were encountered in 1000 consecutive kidney transplants between April ...
journal_title：ANZ journal of surgery
pub_type： 杂志文章
doi：10.1046/j.1445-2197.2003.t01-1-02650.x
更新日期：2003-06-01 00:00:00
abstract：BACKGROUND:Risk factors for bile leakage after hemihepatectomy are unknown. METHODS:A prospectively maintained database review identified patients undergoing hemihepatectomy between 1 January 2009 and 30 September 2014. Patients were divided into B/C and non-B/C bile leakage groups. Risk factors for bile leakage were ...
journal_title：ANZ journal of surgery
pub_type： 杂志文章
doi：10.1111/ans.13073
更新日期：2017-07-01 00:00:00
abstract：BACKGROUND:An audit performed in the use of non-irradiated femoral head bone graft at the Geelong Hospital over a 10-year period. While it is thought the non-irradiated bone graft provides a better structural construct there is theoretical increased risk of infection transmission. METHODS:We performed a retrospective ...
journal_title：ANZ journal of surgery
pub_type： 杂志文章
doi：10.1111/j.1445-2197.2008.04800.x
更新日期：2009-01-01 00:00:00
abstract：:Clinically, solitary thyroid nodules are common, being present in up to 50% of the elderly population. The majority are benign with thyroid cancer representing an uncommon clinical problem. Investigation should include careful history and examination and thyroid function tests. Toxic or autonomous nodules are rarely m...
journal_title：ANZ journal of surgery
pub_type： 杂志文章,评审
doi：10.1111/j.1445-2197.2006.03727.x
更新日期：2006-05-01 00:00:00
abstract：:Technical improvements, equipment to minimize bleeding and standardizing setup positions have allowed shoulder arthroscopy to become more user friendly in diagnosis and treatment of disorders of this joint complex. ...
journal_title：ANZ journal of surgery
pub_type： 杂志文章
doi：10.1111/j.1445-2197.2008.04758.x
更新日期：2008-12-01 00:00:00
abstract：BACKGROUND:In 1987, a report from this unit described the changing indications for open adrenalectomy over a 15-year period. The indications for adrenalectomy had switched from it being the principal therapeutic procedure used in advanced breast cancer in the early 1970s, to being predominately performed for Cushing's ...
journal_title：ANZ journal of surgery
pub_type： 杂志文章
doi：10.1046/j.1445-2197.2002.02454.x
更新日期：2002-07-01 00:00:00
abstract：BACKGROUND:Currently no consensus exists regarding what pre-reversal investigations are required to assess integrity of the rectal anastomosis. The objective of this study was to compare pre-reversal assessments of anastomotic integrity and to evaluate trends that might have influenced timings for reversal. METHODS:Fr...
journal_title：ANZ journal of surgery
pub_type： 杂志文章
doi：10.1111/ans.16483
更新日期：2020-12-09 00:00:00
abstract：:In the early years of the introduction of Christianity into China, one American medical missionary distinguished himself by his kindness and generosity towards the Chinese people, and also by his surgical prowess. Peter Parker (1804-1888) was a graduate from the Yale University Medical School and was also an ordained ...
journal_title：ANZ journal of surgery
pub_type： 传,历史文章,杂志文章
doi：10.1111/ans.12402
更新日期：2013-12-01 00:00:00
abstract：BACKGROUND:This study aimed to investigate incidence of surgical site infection (SSI) following the surgery of intra-articular fractures of distal femur. METHODS:Between July 2014 and December 2017, inpatient medical records of consecutive patients who had intra-articular fractures of distal femur treated by open redu...
journal_title：ANZ journal of surgery
pub_type： 杂志文章
doi：10.1111/ans.15263
更新日期：2019-06-01 00:00:00
abstract：:The article is a summary of some of the pertinent literature on professionalism, highlighting the difference between how physicians understand professionalism and how other groups e.g. politicians, nurses and hospital managers might view the professionalism of doctors. It partly explains why surgeons have become incre...
journal_title：ANZ journal of surgery
pub_type： 杂志文章
doi：10.1111/j.1445-2197.2008.04822.x
更新日期：2009-03-01 00:00:00
abstract：BACKGROUND:The work hours of junior doctors have been in the spotlight since the mid-1980s. Rostering and the structure of surgical units aim to balance quality and continuity of patient care with reasonable working hours. METHODS:Actual hours worked during two 12-week surgical registrar rosters were compared. Complia...
journal_title：ANZ journal of surgery
pub_type： 杂志文章
doi：10.1111/j.1445-2197.2010.05374.x
更新日期：2010-07-01 00:00:00
abstract：BACKGROUND:Although several growth factors are known to be essential for liver regeneration, the role of gastrin remains controversial. METHODS:Liver regeneration was examined in wild-type (WT) and gastrin-deficient (gastrin KO) mice at days 2 and 10 after partial (40%) hepatectomy by measurement of liver weight. Hepa...
journal_title：ANZ journal of surgery
pub_type： 杂志文章
doi：10.1111/j.1445-2197.2007.04360.x
更新日期：2008-01-01 00:00:00
abstract：BACKGROUND:Open cholecystectomy is still a fairly frequently performed operation worldwide, and is used where laparoscopic surgery has failed or is contraindicated, and where some surgeons do not operate laparoscopically for technical reasons. In developing countries laparoscopic cholecystectomy is costly and is availa...
journal_title：ANZ journal of surgery
pub_type： 杂志文章
doi：10.1046/j.1440-1622.2001.02046.x
更新日期：2001-02-01 00:00:00
abstract：BACKGROUND:Rural and regional Australia presents a unique challenge in the delivery of surgical services by virtue of its geographical vastness and low population density. While up to 33% of Australians live in rural or regional areas, only 14.8% of surgeons work in a rural or regional area. Data regarding the caseload...
journal_title：ANZ journal of surgery
pub_type： 杂志文章
doi：10.1111/ans.14680
更新日期：2019-06-01 00:00:00
abstract：BACKGROUND:Fournier's disease is a potentially fatal, acute, gangrenous infection of the scrotum, penis or perineum associated with a synergistic bacterial infection of the subcutaneous fat and superficial fascia. METHODS:The clinical records of 70 patients treated for Fournier's gangrene were evaluated retrospectivel...
journal_title：ANZ journal of surgery
pub_type： 杂志文章
doi：10.1111/j.1445-2197.2006.03975.x
更新日期：2007-01-01 00:00:00
abstract：BACKGROUND:We assessed the accuracy of three different methods measuring the angle between two fixed Kirschner wires for the potential purpose of determining correction during rotational osteotomy of long bones. METHODS:Thirty-one orthopaedic consultants and registrars were prospectively asked to measure the angle bet...
journal_title：ANZ journal of surgery
pub_type： 杂志文章
doi：10.1111/ans.12371
更新日期：2013-12-01 00:00:00
abstract：BACKGROUND:There are well-described benefits to separating emergency and elective surgery. Geelong Hospital lacked the resources to implement a separate acute surgical unit, but instituted daily dedicated emergency general surgery operating sessions, managed by an on-site consultant. This study aims to assess the impac...
journal_title：ANZ journal of surgery
pub_type： 杂志文章
doi：10.1111/ans.12001
更新日期：2013-07-01 00:00:00
abstract：:With the widespread use of abdominal imaging, the detection and therefore incidence of adrenal tumours is increasing. The laparoscopic approach to primary surgical resection of adrenal tumours has now become the standard of care. There is scarce published literature regarding the management and outcomes of recurrent a...
journal_title：ANZ journal of surgery
pub_type： 杂志文章
doi：10.1111/j.1445-2197.2009.04892.x
更新日期：2009-05-01 00:00:00
abstract：BACKGROUND:While recent studies have shown patients with developmental dysplasia of the hip (DDH) undergoing total hip arthroplasty (THA) to achieve comparable post-operative outcomes to patients with primary osteoarthritis (OA), it is unclear whether DDH patients display better or worse preoperative function than the ...
journal_title：ANZ journal of surgery
pub_type： 杂志文章
doi：10.1111/j.1445-2197.2012.06198.x
更新日期：2013-07-01 00:00:00
abstract：BACKGROUND:The aim of this study was to investigate pancreatic injury after 45 min of thoracoabdominal aortic occlusion in a porcine model. METHODS:Twenty-four pigs were used. Six pigs underwent sham operation and 18 intravascular balloon thoracoabdominal aortic occlusions for 45 min. The animals were randomly killed ...
journal_title：ANZ journal of surgery
pub_type： 杂志文章
doi：10.1111/j.1445-2197.2007.04098.x
更新日期：2007-06-01 00:00:00
abstract：BACKGROUND:The aim of this study was to identify factors associated with rupture in elderly patients with acute appendicitis. METHODS:The medical records of 601 consecutive patients >60 years of age with acute appendicitis between 1995 and 2005 were retrospectively reviewed. Historical, clinical and laboratory factors...
journal_title：ANZ journal of surgery
pub_type： 杂志文章
doi：10.1111/j.1445-2197.2007.04182.x
更新日期：2007-08-01 00:00:00
abstract：BACKGROUND:Perioperative hypothermia occurs frequently and can have serious health-related and financial consequences. Despite multiple warming methods available, perioperative hypothermia remains prevalent. To be effective, preventative measures must be timely and target patients most at risk. The aim of this retrospe...
journal_title：ANZ journal of surgery
pub_type： 杂志文章
doi：10.1111/ans.12369
更新日期：2014-07-01 00:00:00
