Factors affecting mortality of Fournier's gangrene: review of 70 patients.

Abstract:

BACKGROUND:Fournier's disease is a potentially fatal, acute, gangrenous infection of the scrotum, penis or perineum associated with a synergistic bacterial infection of the subcutaneous fat and superficial fascia. METHODS:The clinical records of 70 patients treated for Fournier's gangrene were evaluated retrospectively to determine prognostic indices and to stress Fournier's Severity Index (FSI), influencing outcome. RESULTS:The mortality rate in this study was 22.8%. Length of the hospitalization time and FSI were detected as effective factors on mortality of Fournier's gangrene (P < 0.05) by Binary Logistic Regression analysis and the area under the receiver operating characteristic curve of these variables was also found to be significant (P < 0.001). The average FSI was determined as 4.66 +/- 2.31 in survivors and 11.56 +/- 2.68 in non-survivors and 5.11 +/- 2.83 in patients with primary genito-urinary infection but 7.56 +/- 4.35 in primary anorectal infection. The FSI was also found predictive of hospitalization time and number of debridements among survivors. CONCLUSION:Fournier's Severity Index is a simplified way of comparing patients with this disease and may also have some significance in predicting outcome. The FSI is a more significant and predictive tool that should be popularized to predict the prognosis in Fournier's gangrene.

journal_name

ANZ J Surg

journal_title

ANZ journal of surgery

authors

Ersay A,Yilmaz G,Akgun Y,Celik Y

doi

10.1111/j.1445-2197.2006.03975.x

subject

Has Abstract

pub_date

2007-01-01 00:00:00

pages

43-8

issue

1-2

eissn

1445-1433

issn

1445-2197

pii

ANS3975

journal_volume

77

pub_type

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