Effectiveness of moxibustion therapy in the treatment of urticaria: A protocol for a systematic review and meta-analysis.

Abstract:

BACKGROUND:Urticaria is a common skin disease in clinic. The main clinical symptoms are sudden attack, various forms, different sizes of wind, and erythema, accompanied by varying degrees of itching. At present, antihistamines, non-specific antiallergic agents, or glucocorticoids are the main treatment, with some side effects and adverse reactions. Moxibustion therapy has shown strong advantages in the treatment of urticaria, and the curative effect is accurate. Therefore, this paper will carry out a systematic evaluation and meta-analysis of the efficacy and safety of moxibustion in the treatment of urticaria. METHODS:Eight electronic databases will be searched, including PubMed, Excerpta Medica Database, Web of Science, Cochrane Library, the China National Knowledge Infrastructure (CNKI), Chinese Science and Technology Periodical Database (VIP), Wanfang Database (WF), and Chinese Biomedical Literature Database (CBM). We will search above electronic databases from the beginning to October 2020, without any language restriction, but involving only the human subjects. Clinical efficacy, including total effective rate or cure rate, and recurrence rate will be accepted as the primary outcomes. The itch level, number of clusters, size of clusters, and laboratory test results will be used as secondary outcomes. The Cochrane Handbook of Systematic Review (5.3.0) RCT risk assessment tool will be used to evaluate the risk of bias by 2 independent researchers. RESULTS:After the completion of this study, the results will be reported, so it is not possible to give accurate results at present. CONCLUSIONS:The results of this study will provide reliable evidence for the efficacy and safety of moxibustion in the treatment of urticaria. INPLASY REGISTRATION NUMBER:INPLASY2020100040.

journal_name

Medicine (Baltimore)

journal_title

Medicine

authors

Deng G,Ye W,Wan Q,Wang J

doi

10.1097/MD.0000000000023481

subject

Has Abstract

pub_date

2020-12-04 00:00:00

pages

e23481

issue

49

eissn

0025-7974

issn

1536-5964

pii

00005792-202012040-00087

journal_volume

99

pub_type

杂志文章

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