Abstract:
BACKGROUND:Irradiation therapy limits the utilization of silicone implants for breast reconstruction due to a significant risk for capsular contracture. The injection of the collagenase of the bacterium Clostridium histolyticum (CCH) might trivialize this risk by providing a minimal-invasive treatment option by capsular contracture degradation. However, efficacy in degrading breast implant capsules induced by fractionated irradiation remains unclear. METHODS:Twenty-four rats in three groups received miniature silicone implants in a submuscular pocket. After 3D dose calculation and treatment field definition, rats of two groups underwent fractionated radiotherapy (6 × 8 Gy) using a linear accelerator. A third group served as control. On day 120, one irradiated group received injections of 0.3 mg/ml collagenase. Administration of plain solvent solution served as control in the two other groups. Outcome parameters included CT-imaging, histology, vessel wall analysis, immunohistochemistry, chemical collagen quantification and gene expression analysis. RESULTS:Fractioned irradiation leads to a significant increase in collagen deposition around silicone implants with higher capsule thickness and collagen density when comparing all groups. Additionally, significant alterations of collagen fiber deposition were evident. Vessel wall thickness was significantly increased after radiotherapy. The injection of collagenase led to a significant reduction of capsule thickness, collagen density and content. However, the collagenase application induced a significant overexpression of TGFβ1. No side effects were monitored. CONCLUSIONS:The CCH proved to be a safe and effective approach to degrade capsule tissue induced by fractionated irradiation in an animal model. This may pave its way for clinical application in implant-based breast reconstruction patients. LEVEL OF EVIDENCE:This journal requires that authors assign a level of evidence to each submission to which Evidence-Based Medicine rankings are applicable. This excludes Review Articles, Book Reviews, and manuscripts that concern Basic Science, Animal Studies, Cadaver Studies, and Experimental Studies. For a full description of these Evidence-Based Medicine ratings, please refer to the Table of Contents or the online Instructions to Authors www.springer.com/00266 .
journal_name
Aesthetic Plast Surgjournal_title
Aesthetic plastic surgeryauthors
Diehm YF,Jost Y,Kotsougiani-Fischer D,Haug V,Splinter M,Häring P,Berger MR,Debus J,Kneser U,Fischer Sdoi
10.1007/s00266-020-01970-1subject
Has Abstractpub_date
2020-09-23 00:00:00eissn
0364-216Xissn
1432-5241pii
10.1007/s00266-020-01970-1pub_type
杂志文章abstract::The APTOS threading procedure is a relatively new method in antifacial ptosis surgery. The reported cases present a small percentage of minor complications. A 57-year-old woman experienced scarring after APTOS threading. Scar biopsy showed an epidermoid inclusion cyst. Epidermoid inclusion cysts are a potential compli...
journal_title:Aesthetic plastic surgery
pub_type: 杂志文章
doi:10.1007/s00266-007-9016-7
更新日期:2008-01-01 00:00:00
abstract::In this paper we present our procedure for the treatment, histopathological diagnosis, and resection of skin cancer in the nasal pyramid and its subsequent reconstruction. Because we are dealing with the most important anatomical feature of the face our goal is an aesthetic reconstruction [2,4] according to the anatom...
journal_title:Aesthetic plastic surgery
pub_type: 杂志文章
doi:10.1007/s002660010135
更新日期:2001-07-01 00:00:00
abstract:BACKGROUND:Macromastia necessitating breast reduction with free nipple grafts often results in a breast shape that lacks upper pole projection. This study aimed to describe and review the experience with use of the Graf/Biggs flap to improve upper pole fullness in patients requiring breast reductions with free nipple g...
journal_title:Aesthetic plastic surgery
pub_type: 杂志文章
doi:10.1007/s00266-010-9509-7
更新日期:2010-12-01 00:00:00
abstract:BACKGROUND:Over the past few years, treatment of burn scars with lipofilling has shown encouraging clinical results in terms of texture, color, softness, and quality of skin patterns. This clinical application has been widened to include treatment for scars resulting from surgical correction of cicatricial ectropion. I...
journal_title:Aesthetic plastic surgery
pub_type: 杂志文章
doi:10.1007/s00266-008-9117-y
更新日期:2008-05-01 00:00:00
abstract:BACKGROUND:Pseudoptosis (bottoming out) is a well-observed phenomenon occurring after all types of breast reduction surgery. The authors' team previously reported the use of three-dimensional (3D) imaging to demonstrate that significant morphologic changes occur in the breast during the first year after short-scar medi...
journal_title:Aesthetic plastic surgery
pub_type: 杂志文章
doi:10.1007/s00266-010-9615-6
更新日期:2011-06-01 00:00:00
abstract::Is aesthetic surgery a business guided by market structures aimed primarily at material gain and profit or a surgical intervention intended to benefit patients and an integral part of the health-care system? Is it a frivolous subspecialty or does it provide a real and much needed service to a wide range of patients? A...
journal_title:Aesthetic plastic surgery
pub_type: 杂志文章,评审
doi:10.1007/s00266-020-01821-z
更新日期:2020-08-01 00:00:00
abstract::Three disadvantages are frequent after parotidectomy: a scar affecting the neck, a deep hollow between the sternocleidomastoid muscle and the mandible (the larger the resection is, the deeper is the hollow), and a sweat secretion. These disadvantages can be prevented or reduced by using four simple procedures: (1) usi...
journal_title:Aesthetic plastic surgery
pub_type: 杂志文章
doi:10.1007/s002669900234
更新日期:1999-01-01 00:00:00
abstract::An examination of the naso-frontal angle shows that a cranial or caudal shift in position affects the dorsum length. The fundamental aspect characterizing the naso-frontal angle is its width: it may be normal, too wide, or too narrow. It's easier to modify a too-narrow angle than a too-wide one. We show surgical techn...
journal_title:Aesthetic plastic surgery
pub_type: 杂志文章
doi:10.1007/s002660010085
更新日期:2001-01-01 00:00:00
abstract::A case of herpes zoster neuritis (shingles) is reported, closely following a face lift with adjunctive dermabrasion and chemical peel. The etiologic relationships are unclear. However, the mental nerve distribution suggests mechanical irritation of the nerve as a possible factor. Management of this complication is con...
journal_title:Aesthetic plastic surgery
pub_type: 杂志文章
doi:10.1007/BF01570380
更新日期:1988-02-01 00:00:00
abstract:BACKGROUND:A percutaneous electrocauterization technique for the treatment of deep hemangiomas is introduced as an alternative and minimally invasive treatment mode. METHODS:Percutaneous electrothrombosis was applied through a needle-catheter that is a small silicone catheter with a needle guide in it. Thus, it is pos...
journal_title:Aesthetic plastic surgery
pub_type: 杂志文章
doi:10.1007/s00266-009-9425-x
更新日期:2010-04-01 00:00:00
abstract::Revision rhinoplasties and saddle nose deformities usually require grafting for reconstruction. Between January 1, 2000, and January 1, 2017, autologous rib grafts were used in 127 secondary and tertiary rhinoplasty patients [(57/127 females) and (70/127 males)]. Osseous-cartilaginous rib grafts (OCRGs) were divided i...
journal_title:Aesthetic plastic surgery
pub_type: 杂志文章
doi:10.1007/s00266-017-0916-x
更新日期:2017-10-01 00:00:00
abstract::The tumescent technique is very effective for subfascial breast implant surgery. A total amount volume of 330 cc (120/160 cc for each breast) ensures a clean and bloodless field, leading to less postoperative bruising and prolonged local anaesthesia effects. The surgical procedure can be performed with or without asso...
journal_title:Aesthetic plastic surgery
pub_type: 杂志文章
doi:10.1007/s00266-020-01723-0
更新日期:2020-10-01 00:00:00
abstract::The authors present their experience in two-team work in subcutaneous mastectomy, where the mastologists are responsible for the pathology of the breast and the plastic surgeon is responsible for the aesthetics and some of the complications arising from their aesthetical work. They make a minute study of existing oper...
journal_title:Aesthetic plastic surgery
pub_type: 杂志文章
doi:10.1007/BF01577956
更新日期:1978-12-01 00:00:00
abstract:BACKGROUND:Aquafilling filler is used for breast and buttock augmentation, which are the most commonly performed cosmetic surgery procedures. However, complications after using Aquafilling filler for breast augmentation have been reported, and there are concerns regarding its use in large areas, such as the buttocks. W...
journal_title:Aesthetic plastic surgery
pub_type: 杂志文章
doi:10.1007/s00266-020-01889-7
更新日期:2020-12-01 00:00:00
abstract::The purpose of this study was to evaluate the histologic changes that occur after dermabrasion and chemical peel in an animal model that has been pretreated with topical Retin-A. Since human skin and guinea pig skin are very similar in architecture, pretreatment of the latter with Retin-A may reflect what would occur ...
journal_title:Aesthetic plastic surgery
pub_type: 杂志文章
doi:10.1007/BF00451097
更新日期:1995-05-01 00:00:00
abstract:BACKGROUND:Lipoabdominoplasty is nearly a daily aesthetic procedure. Despite the emergence of laser-assisted liposuction, to date, it has not been clearly evaluated combined with abdominoplasty. This prospective study aimed to evaluate the effectiveness and safety of laser-assisted liposuction relative to traditional l...
journal_title:Aesthetic plastic surgery
pub_type: 杂志文章,随机对照试验
doi:10.1007/s00266-013-0242-x
更新日期:2014-02-01 00:00:00
abstract::As more people seek body contour surgery spurred on by the media's great interest in suction lipectomy and the seemingly increasing numbers of satisfied patients, we should re-examine an area where results of body contour surgery have been less satisfying, the inner thigh. In those patients whose problem remains skin ...
journal_title:Aesthetic plastic surgery
pub_type: 杂志文章
doi:10.1007/BF01571478
更新日期:1989-04-01 00:00:00
abstract::There has been a great deal of controversy regarding the safety of silicone breast implants. Silicone gel prostheses older than 10 years have the risk of either leakage or outright rupture. The role of silicone gel in relation to connective tissue disease or amyloidosis has not been proved by current serologic, immuno...
journal_title:Aesthetic plastic surgery
pub_type: 杂志文章
doi:10.1007/s00266-002-2022-x
更新日期:2002-09-01 00:00:00
abstract:BACKGROUND:Capsular contracture can be an ongoing problem in breast augmentation even with good surgical technique. In the author's practice, a higher incidence of capsular contracture was observed with the use of a periareolar incision than with an inframammary incision. METHODS:A review of breast augmentations perfo...
journal_title:Aesthetic plastic surgery
pub_type: 杂志文章
doi:10.1007/s00266-007-9061-2
更新日期:2008-03-01 00:00:00
abstract:BACKGROUND:Nipple reconstruction is usually performed as a separate procedure, several months after the primary breast reconstruction. This study compared the outcomes of immediate and delayed nipple reconstructions during implant-based breast reconstructions. METHODS:A retrospective review was conducted of patients w...
journal_title:Aesthetic plastic surgery
pub_type: 杂志文章
doi:10.1007/s00266-017-0804-4
更新日期:2017-08-01 00:00:00
abstract:BACKGROUND:The scroll area of the nose is important for breathing; thereby, its reconstruction can improve the nasal patency. OBJECTIVE:To evaluate the effect of scroll reconstruction on breathing in patients following open rhinoplasty. METHODS:Using the prospective controlled study design, we enrolled a cohort of pa...
journal_title:Aesthetic plastic surgery
pub_type: 杂志文章
doi:10.1007/s00266-020-02125-y
更新日期:2021-01-28 00:00:00
abstract::In plastic breast surgery, the interlocking areolar suture has gained wide popularity since its introduction in 2007 by Hammond and colleagues. The interlocking circumareolar suture plays its role in the setting of circumareolar excisions to achieve a durable areola shaping and to prevent scar widening/hypertrophy and...
journal_title:Aesthetic plastic surgery
pub_type: 信件
doi:10.1007/s00266-013-0186-1
更新日期:2013-10-01 00:00:00
abstract::There is a renewed interest in the anatomy of the subcutaneous fat. These studies have been stimulated by the recent clinical popularity of liposuction. Attention has been drawn to the superficial fascia system and to its role in wound healing and in skin contraction. What is the origin of this SFS? This article propo...
journal_title:Aesthetic plastic surgery
pub_type: 社论
doi:10.1007/BF00636259
更新日期:1993-07-01 00:00:00
abstract::Body-contouring aesthetic surgery focused on the gluteal region has been increasingly in demand. This article aims to describe the surgical technique, the results, and the complications for 28 women who underwent endoscopically assisted gluteoplasty using high-profile, high-cohesion round silicone implants between 199...
journal_title:Aesthetic plastic surgery
pub_type: 杂志文章
doi:10.1007/s00266-006-0256-8
更新日期:2007-11-01 00:00:00
abstract:BACKGROUND:The treatment of a tuberous breast deformity has changed over the years, with a large variety of procedures described. However, maintaining a long-lasting breast contour is an ongoing challenge. The aim of this study was to evaluate the long-term results of tuberous breast corrections, focusing on the incide...
journal_title:Aesthetic plastic surgery
pub_type: 杂志文章
doi:10.1007/s00266-017-0902-3
更新日期:2017-12-01 00:00:00
abstract::Poly-L-lactic acid (PLLA) (Sculptra, Dermik Laboratories, Bridgewater, NJ, a business of sanofi-aventis US, LLC) is a novel biocompatible and biodegradable injectable device currently under review by the Food and Drug Administration for a cosmetic indication. When implanted into soft tissues, PLLA is thought to elicit...
journal_title:Aesthetic plastic surgery
pub_type: 杂志文章
doi:10.1007/s00266-008-9112-3
更新日期:2008-05-01 00:00:00
abstract:UNLABELLED:Breast implants are frequently used for both cosmetic breast augmentation and breast reconstruction after mastectomy. Three companies currently offer FDA-approved breast implants (Allergan, Mentor, and Sientra), but their product offerings-including permanent breast implants, breast tissue expanders, sizers,...
journal_title:Aesthetic plastic surgery
pub_type: 杂志文章,评审
doi:10.1007/s00266-015-0537-1
更新日期:2015-10-01 00:00:00
abstract:BACKGROUND:Acute swelling of the parotid glands after general anesthesia has become known as anesthesia mumps. Its cause is unknown. Only one case of postsurgical parotitis without general anesthesia is reported. This report describes three cases in this setting after plastic surgery. CASE 1:A 37-year-old women underw...
journal_title:Aesthetic plastic surgery
pub_type: 杂志文章
doi:10.1007/s00266-013-0112-6
更新日期:2013-08-01 00:00:00
abstract:BACKGROUND:Fat-preserving lower blepharoplasty techniques and filling techniques using autologous or non-autologous materials are increasingly used to treat tear trough deformity. However, there has been no definitive comparison of the results of fat repositioning versus autologous fat grafting for this condition. The ...
journal_title:Aesthetic plastic surgery
pub_type: 杂志文章
doi:10.1007/s00266-016-0692-z
更新日期:2017-02-01 00:00:00
abstract:BACKGROUND:This study was conducted to compare the effect of photobiomodulation therapy (low-level laser therapy) on ecchymosis after rhinoplasty. SUBJECTS AND METHODS:Sixty rhinoplasty candidates were randomly divided into two groups. Photobiomodulation, including red light (660 nm), infrared light (840 nm), and infr...
journal_title:Aesthetic plastic surgery
pub_type: 杂志文章,随机对照试验
doi:10.1007/s00266-020-01760-9
更新日期:2020-10-01 00:00:00