Intercostal Nerve Block with Liposomal Bupivacaine vs Epidural Analgesia for the Treatment of Traumatic Rib Fracture.

Abstract:

BACKGROUND:Rib fractures are common among trauma patients and analgesia remains the cornerstone of treatment. Intercostal nerve blocks provide analgesia but are limited by the duration of the anesthetic. This study compares outcomes of epidural analgesia with intercostal nerve block using liposomal bupivacaine for the treatment of traumatic rib fractures. METHODS:A retrospective chart review was used to identify patients who received either epidural analgesia or intercostal nerve block with liposomal bupivacaine for the treatment of traumatic rib fractures. Patients were matched in a 1:1 ratio on age, Injury Severity Score, and number of rib fractures. Outcomes included intubations, mechanical ventilation days, ICU length of stay (LOS), hospital LOS, and mortality. RESULTS:After matching, 116 patients were included in the study. Patients receiving intercostal nerve blocks with liposomal bupivacaine were less likely to require intubation (3% vs 17%; p = 0.015), had shorter hospital LOS (mean ± SD 8 ± 6 days vs 11 ± 9 days; p = 0.020) and ICU LOS (mean ± SD 2 ± 5 days vs 5 ± 6 days; p = 0.007). There were no differences in ventilator days or mortality. Minor complications occurred in 26% of patients that received an epidural catheter for rib fractures. No complications occurred in the patients receiving intercostal nerve block. CONCLUSIONS:Patients who received intercostal nerve blocks with liposomal bupivacaine required intubation less frequently and had shorter ICU and hospital LOS compared with epidural analgesia patients. These results suggest that intercostal nerve blocks with liposomal bupivacaine might be equal or superior to epidural analgesia.

journal_name

J Am Coll Surg

authors

Sheets NW,Davis JW,Dirks RC,Pang AW,Kwok AM,Wolfe MM,Sue LP

doi

10.1016/j.jamcollsurg.2019.12.044

subject

Has Abstract

pub_date

2020-07-01 00:00:00

pages

150-154

issue

1

eissn

1072-7515

issn

1879-1190

pii

S1072-7515(20)30174-5

journal_volume

231

pub_type

杂志文章
  • What are the real rates of postoperative complications: elucidating inconsistencies between administrative and clinical data sources.

    abstract:BACKGROUND:Comparison of quality outcomes generated from administrative and clinical datasets have shown inconsistencies. Understanding this is important because data designed to drive performance improvement are used for public reporting of performance. We examined administrative and clinical data and 2 clinical data ...

    journal_title:Journal of the American College of Surgeons

    pub_type: 杂志文章

    doi:10.1016/j.jamcollsurg.2011.12.037

    authors: Koch CG,Li L,Hixson E,Tang A,Phillips S,Henderson JM

    更新日期:2012-05-01 00:00:00

  • One Thousand Pediatric Liver Transplants During Thirty Years: Lessons Learned.

    abstract:BACKGROUND:Pediatric liver transplantation (pLTx) has been the standard of care for children with liver failure since the 1980s. This study examined the world's largest single-center experience and aimed to identify unique preoperative predictors of early graft and patient survival for primary transplantation (1°-pLTx)...

    journal_title:Journal of the American College of Surgeons

    pub_type: 杂志文章

    doi:10.1016/j.jamcollsurg.2017.12.042

    authors: Venick RS,Farmer DG,Soto JR,Vargas J,Yersiz H,Kaldas FM,Agopian VG,Hiatt JR,McDiarmid SV,Busuttil RW

    更新日期:2018-04-01 00:00:00

  • Longterm followup assessment of a HER2/neu peptide (E75) vaccine for prevention of recurrence in high-risk prostate cancer patients.

    abstract:BACKGROUND:E75 is an immunogenic peptide from the HER2/neu protein that is expressed in prostate cancer. High-risk prostate cancer (HRPC) patients demonstrating varying levels of HER2/neu expression were vaccinated with E75 peptide plus granulocyte-macrophage colony-stimulating factor to prevent postprostatectomy PSA a...

    journal_title:Journal of the American College of Surgeons

    pub_type: 杂志文章

    doi:10.1016/j.jamcollsurg.2008.10.018

    authors: Gates JD,Carmichael MG,Benavides LC,Holmes JP,Hueman MT,Woll MM,Ioannides CG,Robson CH,McLeod DG,Ponniah S,Peoples GE

    更新日期:2009-02-01 00:00:00

  • Morbidity and mortality as a televideoconference: a randomized prospective evaluation of learning and perceptions.

    abstract:BACKGROUND:Central morbidity and mortality conferences ensure uniform content and more participants but consume work hours in commuting for programs with multiple teaching hospitals. Internet-based televideoconferencing (TVC) technology has the potential to eliminate commuting and expand participation and retain qualit...

    journal_title:Journal of the American College of Surgeons

    pub_type: 杂志文章,随机对照试验

    doi:10.1016/j.jamcollsurg.2010.12.002

    authors: Lewis CE,Relan A,Hines OJ,Tillou A,Hiatt JR

    更新日期:2011-03-01 00:00:00

  • Three years clinical experience with intestinal transplantation.

    abstract:BACKGROUND:After the successful evolution of hepatic transplantation during the last decade, small bowel and multivisceral transplantation remains the sole elusive achievement for the next era of transplant surgeons. Until recently, and for the last thirty years, the results of the sporadic attempts of intestinal trans...

    journal_title:Journal of the American College of Surgeons

    pub_type: 杂志文章

    doi:

    authors: Abu-Elmagd K,Todo S,Tzakis A,Reyes J,Nour B,Furukawa H,Fung JJ,Demetris A,Starzl TE

    更新日期:1994-10-01 00:00:00

  • The importance of the first complication: understanding failure to rescue after emergent surgery in the elderly.

    abstract:BACKGROUND:Perioperative mortality in the elderly is high after emergency surgery and varies considerably among hospitals-an observation partially explained by differences in failure to rescue. We hypothesize that failure to rescue after certain types of complications underlies the disproportionately poor outcomes obse...

    journal_title:Journal of the American College of Surgeons

    pub_type: 杂志文章

    doi:10.1016/j.jamcollsurg.2014.02.035

    authors: Sheetz KH,Krell RW,Englesbe MJ,Birkmeyer JD,Campbell DA Jr,Ghaferi AA

    更新日期:2014-09-01 00:00:00

  • Does the American College of Surgeons NSQIP-Pediatric Accurately Represent Overall Patient Outcomes?

    abstract:BACKGROUND:The National Surgical Quality Improvement Program-Pediatrics (NSQIP-P) collects data for institutional quality benchmarking of surgery performed on children using a sampling algorithm. The Pediatric and Infant Case Log and Outcomes (PICaLO) is a database of all general and thoracic pediatric surgery (GTPS) p...

    journal_title:Journal of the American College of Surgeons

    pub_type: 杂志文章

    doi:10.1016/j.jamcollsurg.2015.07.014

    authors: Gross ER,Christensen M,Schultz JA,Cassidy LD,Anderson Y,Arca MJ

    更新日期:2015-10-01 00:00:00

  • Esophageal perforation management using a multidisciplinary minimally invasive treatment algorithm.

    abstract:BACKGROUND:The surgical management of esophageal perforation (EP) often results in mortality and significant morbidity. Recent less invasive approaches to EP management include endoscopic luminal stenting and minimally invasive surgical therapies. We wished to establish therapeutic efficacy of minimally invasive therap...

    journal_title:Journal of the American College of Surgeons

    pub_type: 杂志文章

    doi:10.1016/j.jamcollsurg.2013.12.033

    authors: Ben-David K,Behrns K,Hochwald S,Rossidis G,Caban A,Crippen C,Caranasos T,Hughes S,Draganov P,Forsmark C,Chauhan S,Wagh MS,Sarosi G

    更新日期:2014-04-01 00:00:00

  • Fibulin-5 promotes wound healing in vivo.

    abstract:BACKGROUND:Fibulin-5 is a recently discovered multifunctional extracellular matrix protein that mediates endothelial cell adhesion through integrin ligation, regulates cell growth and motility in a context-specific manner, and prevents elastinopathy in vivo. Because fibulin-5 expression is induced dramatically in endot...

    journal_title:Journal of the American College of Surgeons

    pub_type: 杂志文章

    doi:10.1016/j.jamcollsurg.2004.04.021

    authors: Lee MJ,Roy NK,Mogford JE,Schiemann WP,Mustoe TA

    更新日期:2004-09-01 00:00:00

  • Optimal Timing to Surgery after Neoadjuvant Chemoradiotherapy for Locally Advanced Rectal Cancer.

    abstract:BACKGROUND:Neoadjuvant chemoradiotherapy (nCRT) has demonstrated proven benefit in tumor regression and improved long-term local control for patients with locally advanced rectal cancer. However, precise analysis of the optimal waiting time that maximizes oncologic benefits of nCRT has not been established. STUDY DESI...

    journal_title:Journal of the American College of Surgeons

    pub_type: 杂志文章

    doi:10.1016/j.jamcollsurg.2015.12.017

    authors: Sun Z,Adam MA,Kim J,Shenoi M,Migaly J,Mantyh CR

    更新日期:2016-04-01 00:00:00

  • Placental umbilical cord whole blood transfusion: a safe and genuine blood substitute for patients of the under-resourced world at emergency.

    abstract:BACKGROUND:Afterbirth or placenta is normally discarded. But placental cord blood, because of its rich mix of fetal and adult hemoglobin, plasma, and high platelet count has the potential to be a safe alternative to adult blood. STUDY DESIGN:We transfused 413 U (range 50 mL to 146 mL; mean 86 mL+/-7.6 mL SD; median 80...

    journal_title:Journal of the American College of Surgeons

    pub_type: 杂志文章

    doi:10.1016/j.jamcollsurg.2004.12.007

    authors: Bhattacharya N

    更新日期:2005-04-01 00:00:00

  • Interim Analysis of a Prospective Multi-Institutional Study of Surgery Resident Experience with Flexibility in Surgical Training.

    abstract:BACKGROUND:The Flexibility in Surgical Training (FIST) consortium project was designed to evaluate the feasibility and resident outcomes of optional subspecialty-focused training within general surgery residency training. STUDY DESIGN:After approval by the American Board of Surgery, R4 and R5 residents were permitted ...

    journal_title:Journal of the American College of Surgeons

    pub_type: 杂志文章,多中心研究

    doi:10.1016/j.jamcollsurg.2017.12.024

    authors: Cullinan DR,Wise PE,Delman KA,Potts JR,Awad MM,Eberlein TJ,Klingensmith ME

    更新日期:2018-04-01 00:00:00

  • Success of carotid endarterectomy in veterans: high medical risk does not equate with high surgical risk.

    abstract:BACKGROUND:The safety and efficacy of carotid endarterectomy (CEA) in stroke prevention has been well documented. But "high-risk" patients have traditionally been excluded from these studies and may be offered alternate therapies. We examined the safety of CEA in veterans, a medically high-risk group with multiple como...

    journal_title:Journal of the American College of Surgeons

    pub_type: 杂志文章

    doi:10.1016/j.jamcollsurg.2008.02.033

    authors: Fitzgerald TN,Popp C,Federman DG,Dardik A

    更新日期:2008-08-01 00:00:00

  • Outcomes of hepatectomy for hepatolithiasis based on 3-dimensional reconstruction technique.

    abstract:BACKGROUND:The aim of our study was to evaluate the perioperative and long-term outcomes of hepatectomy based on 3-dimensional reconstruction technique for hepatolithiasis by comparing it with traditional hepatectomy. STUDY DESIGN:From December 2005 to September 2012, 56 consecutive patients underwent hepatectomy base...

    journal_title:Journal of the American College of Surgeons

    pub_type: 杂志文章

    doi:10.1016/j.jamcollsurg.2013.03.017

    authors: Fang CH,Liu J,Fan YF,Yang J,Xiang N,Zeng N

    更新日期:2013-08-01 00:00:00

  • Hospital Variation in Geriatric Surgical Safety for Emergency Operation.

    abstract:BACKGROUND:The American College of Surgeons maintains that surgical care in the US has not reached optimal safety and quality. This can be driven partially by higher-risk, emergency operations in geriatric patients. We therefore sought to answer 2 questions: First, to what degree does standardized postoperative mortali...

    journal_title:Journal of the American College of Surgeons

    pub_type: 杂志文章

    doi:10.1016/j.jamcollsurg.2019.10.018

    authors: Becher RD,Sukumar N,DeWane MP,Stolar MJ,Gill TM,Schuster KM,Maung AA,Zogg CK,Davis KA

    更新日期:2020-06-01 00:00:00

  • Primary fascial closure with mesh reinforcement is superior to bridged mesh repair for abdominal wall reconstruction.

    abstract:BACKGROUND:Many surgeons believe that primary fascial closure with mesh reinforcement should be the goal of abdominal wall reconstruction (AWR), yet others have reported acceptable outcomes when mesh is used to bridge the fascial edges. It has not been clearly shown how the outcomes for these techniques differ. We hypo...

    journal_title:Journal of the American College of Surgeons

    pub_type: 杂志文章

    doi:10.1016/j.jamcollsurg.2013.08.015

    authors: Booth JH,Garvey PB,Baumann DP,Selber JC,Nguyen AT,Clemens MW,Liu J,Butler CE

    更新日期:2013-12-01 00:00:00

  • Are surgical trials with negative results being interpreted correctly?

    abstract:BACKGROUND:Many published accounts of clinical trials report no differences between the treatment arms, while being underpowered to find differences. This study determined how the authors of these reports interpreted their findings. STUDY DESIGN:We examined 54 reports of surgical trials chosen randomly from a database...

    journal_title:Journal of the American College of Surgeons

    pub_type: 杂志文章

    doi:10.1016/j.jamcollsurg.2012.09.015

    authors: Brody BA,Ashton CM,Liu D,Xiong Y,Yao X,Wray NP

    更新日期:2013-01-01 00:00:00

  • The longitudinal study of surgical residents, 1994 to 1996.

    abstract:BACKGROUND:The American College of Surgeons (ACS) has conducted a detailed annual survey of residents enrolled in surgical graduate medical education (GME) programs since 1982 and has regularly published the resulting data as the Longitudinal Study of Surgical Residents. This report documents surgical resident enrollme...

    journal_title:Journal of the American College of Surgeons

    pub_type: 杂志文章

    doi:10.1016/s1072-7515(99)00044-7

    authors: Kwakwa F,Jonasson O

    更新日期:1999-06-01 00:00:00

  • Characteristics and clinical outcome of proximal-third gastric cancer.

    abstract:BACKGROUND:It is generally accepted that the prognosis of patients with proximal gastric cancer (PGC) is worse than that of patients with more distal gastric cancer. STUDY DESIGN:The aim of this study was to compare the clinical features and outcomes of PGC with those of middle- and distal-third gastric cancers. A tot...

    journal_title:Journal of the American College of Surgeons

    pub_type: 杂志文章

    doi:10.1016/s1072-7515(98)00191-4

    authors: Sakaguchi T,Watanabe A,Sawada H,Yamada Y,Tatsumi M,Fujimoto H,Emoto K,Nakano H

    更新日期:1998-10-01 00:00:00

  • Thyroid and parathyroid operations in veterans affairs and selected university medical centers: results of the patient safety in surgery study.

    abstract:BACKGROUND:There is increasing interest in surgical outcomes. The Patient Safety in Surgery (PSS) Study database was examined about thyroid and parathyroid procedures to determine risk factors for adverse outcomes and outcomes rates. Relative outcomes performance for the Veterans Affairs (VA) and private-sector populat...

    journal_title:Journal of the American College of Surgeons

    pub_type: 杂志文章

    doi:10.1016/j.jamcollsurg.2007.02.073

    authors: Hall BL,Hirbe M,Yan Y,Khuri SF,Henderson WG,Hamilton BH

    更新日期:2007-06-01 00:00:00

  • Outcomes of endoscopic and percutaneous drainage of pancreatic fluid collections arising after pancreatic tail resection.

    abstract:BACKGROUND:Up to 15% to 30% of patients develop pancreatic fluid collections (PFCs) after pancreatic tail resection. Percutaneous and endoscopic methods have been used to drain these collections, though few data are available that compare outcomes of these modalities. STUDY DESIGN:From December 1998 to April 2011, we ...

    journal_title:Journal of the American College of Surgeons

    pub_type: 杂志文章

    doi:10.1016/j.jamcollsurg.2012.03.015

    authors: Azeem N,Baron TH,Topazian MD,Zhong N,Fleming CJ,Kendrick ML

    更新日期:2012-08-01 00:00:00

  • Laparoscopic distal pancreatectomy: trends and lessons learned through an 11-year experience.

    abstract:BACKGROUND:As compared with open distal pancreatectomy, laparoscopic distal pancreatectomy (LDP) is associated with lower morbidity and shorter hospital stays. Existing reports do not elucidate trends in patient selection, technique, and outcomes over time. We aimed to determine outcomes after LDP at a specialized cent...

    journal_title:Journal of the American College of Surgeons

    pub_type: 杂志文章

    doi:10.1016/j.jamcollsurg.2012.03.023

    authors: Kneuertz PJ,Patel SH,Chu CK,Fisher SB,Maithel SK,Sarmiento JM,Weber SM,Staley CA,Kooby DA

    更新日期:2012-08-01 00:00:00

  • A novel scoring system for predicting postoperative venous thromboembolic complications in patients after open aortic surgery.

    abstract:BACKGROUND:Although the overall incidence of venous thromboembolism (VTE) after open aortic surgery is low, it is not known whether specific factors can place patients at increased risk for this complication. The goal of our study was to identify patient and procedure characteristics that are associated with increased ...

    journal_title:Journal of the American College of Surgeons

    pub_type: 杂志文章

    doi:10.1016/j.jamcollsurg.2011.12.031

    authors: Scarborough JE,Cox MW,Mureebe L,Pappas TN,Shortell CK

    更新日期:2012-04-01 00:00:00

  • The first decade of a laparoscopic donor nephrectomy program: effect of surgeon and institution experience with 512 cases from 1996 to 2006.

    abstract:BACKGROUND:Although the procedure is generally safe, significant morbidity and even mortality have occurred after laparoscopic donor nephrectomy (LDN). The learning curves for both surgeons and institutions with LDN have not been well delineated, and longterm donor data are not well reported. STUDY DESIGN:A retrospect...

    journal_title:Journal of the American College of Surgeons

    pub_type: 杂志文章

    doi:10.1016/j.jamcollsurg.2009.02.060

    authors: Chin EH,Hazzan D,Edye M,Wisnivesky JP,Herron DM,Ames SA,Palese M,Pomp A,Gagner M,Bromberg JS

    更新日期:2009-07-01 00:00:00

  • Description and evaluation of the Surgeons as Educators course.

    abstract:BACKGROUND:Since 1993, the American College of Surgeons has sponsored an annual 6-day course entitled the Surgeons as Educators. The course was designed to provide academic surgeons with the knowledge and skills necessary to enhance the surgical education curriculum, teaching strategies, educational program administrat...

    journal_title:Journal of the American College of Surgeons

    pub_type: 杂志文章

    doi:

    authors: DaRosa DA,Folse JR,Reznick RK,Dunnington GL,Sachdeva AK

    更新日期:1996-11-01 00:00:00

  • Impact of the COVID-19 Pandemic on Lung Cancer Screening Program and Subsequent Lung Cancer.

    abstract:BACKGROUND:Low-dose CT (LDCT) screening reduces lung cancer mortality by at least 20%. The COVID-19 pandemic required an unprecedented shutdown in our institutional LDCT program. The purpose of this study was to examine the impact of COVID-19 on lung cancer screening and subsequent cancer diagnosis. STUDY DESIGN:We an...

    journal_title:Journal of the American College of Surgeons

    pub_type: 杂志文章

    doi:10.1016/j.jamcollsurg.2020.12.002

    authors: Van Haren RM,Delman AM,Turner KM,Waits B,Hemingway M,Shah SA,Starnes SL

    更新日期:2020-12-17 00:00:00

  • Improved extubation rates and earlier liberation from mechanical ventilation with implementation of a daily spontaneous-breathing trial protocol.

    abstract:BACKGROUND:Daily spontaneous-breathing trials (SBTs) are promulgated as the best method for assessing readiness for discontinuation of mechanical ventilation. SBT protocols have also been shown to improve outcomes as opposed to wild-type implementation of daily SBT recommendations. Here we determine whether implementat...

    journal_title:Journal of the American College of Surgeons

    pub_type: 杂志文章

    doi:10.1016/j.jamcollsurg.2007.08.022

    authors: Robertson TE,Sona C,Schallom L,Buckles M,Cracchiolo L,Schuerer D,Coopersmith CM,Song F,Buchman TG

    更新日期:2008-03-01 00:00:00

  • Predictors of comprehension during surgical informed consent.

    abstract:BACKGROUND:Patient comprehension during surgical informed consent remains problematic. Using data from our randomized trial of methods to improve informed consent comprehension, we performed an additional analysis to define independent factors associated with improved patient understanding. STUDY DESIGN:Patients sched...

    journal_title:Journal of the American College of Surgeons

    pub_type: 杂志文章,多中心研究,随机对照试验

    doi:10.1016/j.jamcollsurg.2010.02.049

    authors: Fink AS,Prochazka AV,Henderson WG,Bartenfeld D,Nyirenda C,Webb A,Berger DH,Itani K,Whitehill T,Edwards J,Wilson M,Karsonovich C,Parmelee P

    更新日期:2010-06-01 00:00:00

  • The nitric oxide donor molsidomine improves survival and reduces hepatocyte apoptosis in cholestasis and endotoxemia.

    abstract:BACKGROUND:Cholestasis and endotoxemia have been demonstrated to cause hepatocyte apoptosis through caspase-mediated pathways. In vitro nitric oxide (NO) donors reduce hepatocyte apoptosis and caspase activation in several models. The nitric oxide donor molsidomine improves survival in an in vivo model of endotoxemia. ...

    journal_title:Journal of the American College of Surgeons

    pub_type: 杂志文章

    doi:10.1016/S1072-7515(03)00386-7

    authors: Brown KM,Brems JJ,Moazzam FN,Hartman GG,Gamelli RL,Ding JW

    更新日期:2003-08-01 00:00:00

  • The Surgeon as the Second Victim? Results of the Boston Intraoperative Adverse Events Surgeons' Attitude (BISA) Study.

    abstract:BACKGROUND:An intraoperative adverse event (iAE) is often directly attributable to the surgeon's technical error and/or suboptimal intraoperative judgment. We aimed to examine the psychological impact of iAEs on surgeons as well as the surgeons' attitude about iAE reporting. STUDY DESIGN:We conducted a web-based cross...

    journal_title:Journal of the American College of Surgeons

    pub_type: 杂志文章,多中心研究

    doi:10.1016/j.jamcollsurg.2016.12.039

    authors: Han K,Bohnen JD,Peponis T,Martinez M,Nandan A,Yeh DD,Lee J,Demoya M,Velmahos G,Kaafarani HMA

    更新日期:2017-06-01 00:00:00