当前位置： SCI文献检索 > NEUROIMAGE期刊下所有文献 > Mouse BOLD fMRI at ultrahigh field detects somatosensory networks including thalamic nuclei.

Mouse BOLD fMRI at ultrahigh field detects somatosensory networks including thalamic nuclei.

Abstract：

:Forepaw somatosensory stimulation induces neural activities in relay thalamic nuclei, the primary somatosensory cortex of forelimb (S1FL), and the secondary somatosensory cortex (S2). However, rodent fMRI studies of somatosensory stimulation have commonly reported BOLD changes only in S1FL, which may be due to side effects of anesthetics and/or the low sensitivity in the thalamus. Thus, we have obtained mouse BOLD fMRI under newly-adopted ketamine-xylazine anesthesia. High-resolution BOLD fMRI obtained with same imaging parameters at 9.4T versus 15.2T shows the improvement of functional detectability by ≥ 2 times at 15.2T due to higher signal intensity and larger BOLD response. The fMRI responses at 15.2T were robustly observed at well-known somatosensory networks including thalamus. Second, echo-time-dependent BOLD signals are dominant based on multi-echo fMRI data. A ratio of BOLD responses in S1FL to thalamus is ∼2, which is not related to different baseline T2∗ or different cerebral blood volume. Third, group-averaged 15.2T BOLD maps show activities in S1FL, S2, motor cortices, and thalamic nuclei, which agree well with neural tracing network data from the Allen Institute, demonstrating that fMRI detects entire somatosensory networks. Our data suggest that ultrahigh field fMRI provides a unique window into understanding functional networks in normal and transgenic mouse models noninvasively.

journal_name

Neuroimage

journal_title

NeuroImage

authors

Jung WB,Shim HJ,Kim SG

doi

10.1016/j.neuroimage.2019.03.063

subject

Has Abstract

pub_date

2019-07-15 00:00:00

pages

203-214

eissn

1053-8119

issn

1095-9572

pii

S1053-8119(19)30263-0

journal_volume

195

pub_type

杂志文章

相关文献

NEUROIMAGE文献大全
  • Fast structural brain imaging using an MDEFT sequence with a FLASH-EPI hybrid readout.

    abstract：:A sequence for the fast acquisition of T1 weighted structural brain images with whole brain coverage and isotropic resolution of 1mm is presented. It is based on MDEFT with a FLASH-EPI hybrid readout. Several techniques for artefact suppression are implemented, like echo time shifting, asymmetric k-space sampling, and...

    journal_title：NeuroImage

    pub_type： 杂志文章

    doi：10.1016/j.neuroimage.2006.08.005

    authors： Deichmann R

    更新日期：2006-12-01 00:00:00

  • Integration of iconic gestures and speech in left superior temporal areas boosts speech comprehension under adverse listening conditions.

    abstract：:Iconic gestures are spontaneous hand movements that illustrate certain contents of speech and, as such, are an important part of face-to-face communication. This experiment targets the brain bases of how iconic gestures and speech are integrated during comprehension. Areas of integration were identified on the basis o...

    journal_title：NeuroImage

    pub_type： 杂志文章

    doi：10.1016/j.neuroimage.2009.08.058

    authors： Holle H,Obleser J,Rueschemeyer SA,Gunter TC

    更新日期：2010-01-01 00:00:00

  • Functional magnetic resonance imaging characterization of CCK-4-induced panic attack and subsequent anticipatory anxiety.

    abstract：:The main objective of this work was to study the functional markers of the clinical response to cholecystokinin tetrapeptide (CCK-4). Twelve healthy male subjects were challenged with CCK-4 and simultaneously underwent functional magnetic resonance imaging (fMRI) recording. Since anticipatory anxiety (AA) is an intrin...

    journal_title：NeuroImage

    pub_type： 杂志文章

    doi：10.1016/j.neuroimage.2006.01.035

    authors： Schunck T,Erb G,Mathis A,Gilles C,Namer IJ,Hode Y,Demaziere A,Luthringer R,Macher JP

    更新日期：2006-07-01 00:00:00

  • Modulation of neuronal oscillatory activity in the beta- and gamma-band is associated with current individual anxiety levels.

    abstract：:Human faces are among the most salient visual stimuli and act both as socially and emotionally relevant signals. Faces and especially faces with emotional expression receive prioritized processing in the human brain and activate a distributed network of brain areas reflected, e.g., in enhanced oscillatory neuronal act...

    journal_title：NeuroImage

    pub_type： 杂志文章

    doi：10.1016/j.neuroimage.2018.05.059

    authors： Schneider TR,Hipp JF,Domnick C,Carl C,Büchel C,Engel AK

    更新日期：2018-09-01 00:00:00

  • Neural prediction of higher-order auditory sequence statistics.

    abstract：:During auditory perception, we are required to abstract information from complex temporal sequences such as those in music and speech. Here, we investigated how higher-order statistics modulate the neural responses to sound sequences, hypothesizing that these modulations are associated with higher levels of the peri-S...

    journal_title：NeuroImage

    pub_type： 杂志文章

    doi：10.1016/j.neuroimage.2010.10.038

    authors： Furl N,Kumar S,Alter K,Durrant S,Shawe-Taylor J,Griffiths TD

    更新日期：2011-02-01 00:00:00

  • Linking ordering in Broca's area to storage in left temporo-parietal regions: the case of sentence processing.

    abstract：:In sentence processing, storage and ordering of the verb and its arguments (subject and object) are core tasks. Their cortical representation is a matter of ongoing debate, and it is unclear whether prefrontal activations in neuroimaging studies on sentence processing reflect the storage of arguments or their ordering...

    journal_title：NeuroImage

    pub_type： 杂志文章

    doi：10.1016/j.neuroimage.2012.05.052

    authors： Meyer L,Obleser J,Anwander A,Friederici AD

    更新日期：2012-09-01 00:00:00

  • Meta-analytic clustering of the insular cortex: characterizing the meta-analytic connectivity of the insula when involved in active tasks.

    abstract：:The human insula has been parcellated on the basis of resting state functional connectivity and diffusion tensor imaging. Little is known about the organization of the insula when involved in active tasks. We explored this issue using a novel meta-analytic clustering approach. We queried the BrainMap database asking f...

    journal_title：NeuroImage

    pub_type： 杂志文章,meta分析

    doi：10.1016/j.neuroimage.2012.04.012

    authors： Cauda F,Costa T,Torta DM,Sacco K,D'Agata F,Duca S,Geminiani G,Fox PT,Vercelli A

    更新日期：2012-08-01 00:00:00

  • Multi-atlas segmentation of the whole hippocampus and subfields using multiple automatically generated templates.

    abstract：INTRODUCTION:Advances in image segmentation of magnetic resonance images (MRI) have demonstrated that multi-atlas approaches improve segmentation over regular atlas-based approaches. These approaches often rely on a large number of manually segmented atlases (e.g. 30-80) that take significant time and expertise to prod...

    journal_title：NeuroImage

    pub_type： 杂志文章

    doi：10.1016/j.neuroimage.2014.04.054

    authors： Pipitone J,Park MT,Winterburn J,Lett TA,Lerch JP,Pruessner JC,Lepage M,Voineskos AN,Chakravarty MM,Alzheimer's Disease Neuroimaging Initiative.

    更新日期：2014-11-01 00:00:00

  • Commonality of neural representations of words and pictures.

    abstract：:In this work we explore whether the patterns of brain activity associated with thinking about concrete objects are dependent on stimulus presentation format, whether an object is referred to by a written or pictorial form. Multi-voxel pattern analysis methods were applied to brain imaging (fMRI) data to identify the i...

    journal_title：NeuroImage

    pub_type： 杂志文章

    doi：10.1016/j.neuroimage.2010.10.042

    authors： Shinkareva SV,Malave VL,Mason RA,Mitchell TM,Just MA

    更新日期：2011-02-01 00:00:00

  • Functional brain network organisation of children between 2 and 5 years derived from reconstructed activity of cortical sources of high-density EEG recordings.

    abstract：:There is increasing interest in applying connectivity analysis to brain measures (Rubinov and Sporns, 2010), but most studies have relied on fMRI, which substantially limits the participant groups and numbers that can be studied. High-density EEG recordings offer a comparatively inexpensive easy-to-use alternative, bu...

    journal_title：NeuroImage

    pub_type： 杂志文章

    doi：10.1016/j.neuroimage.2013.06.003

    authors： Bathelt J,O'Reilly H,Clayden JD,Cross JH,de Haan M

    更新日期：2013-11-15 00:00:00

  • Probabilistic model-based functional parcellation reveals a robust, fine-grained subdivision of the striatum.

    abstract：:The striatum is involved in many different aspects of behaviour, reflected by the variety of cortical areas that provide input to this structure. This input is topographically organized and is likely to result in functionally specific signals. Such specificity can be examined using functional clustering approaches. He...

    journal_title：NeuroImage

    pub_type： 杂志文章

    doi：10.1016/j.neuroimage.2015.06.084

    authors： Janssen RJ,Jylänki P,Kessels RP,van Gerven MA

    更新日期：2015-10-01 00:00:00

  • Variational, geometric, and statistical methods for modeling brain anatomy and function.

    abstract：:We survey the recent activities of the Odyssée Laboratory in the area of the application of mathematics to the design of models for studying brain anatomy and function. We start with the problem of reconstructing sources in MEG and EEG, and discuss the variational approach we have developed for solving these inverse p...

    journal_title：NeuroImage

    pub_type： 杂志文章,评审

    doi：10.1016/j.neuroimage.2004.07.015

    authors： Faugeras O,Adde G,Charpiat G,Chefd'hotel C,Clerc M,Deneux T,Deriche R,Hermosillo G,Keriven R,Kornprobst P,Kybic J,Lenglet C,Lopez-Perez L,Papadopoulo T,Pons JP,Segonne F,Thirion B,Tschumperlé D,Viéville T,Wotawa N

    更新日期：2004-01-01 00:00:00

  • Prediction of Alzheimer's disease in subjects with mild cognitive impairment from the ADNI cohort using patterns of cortical thinning.

    abstract：:Predicting Alzheimer's disease (AD) in individuals with some symptoms of cognitive decline may have great influence on treatment choice and disease progression. Structural magnetic resonance imaging (MRI) has the potential of revealing early signs of neurodegeneration in the human brain and may thus aid in predicting ...

    journal_title：NeuroImage

    pub_type： 杂志文章

    doi：10.1016/j.neuroimage.2012.09.058

    authors： Eskildsen SF,Coupé P,García-Lorenzo D,Fonov V,Pruessner JC,Collins DL,Alzheimer's Disease Neuroimaging Initiative.

    更新日期：2013-01-15 00:00:00

  • Longitudinal multiple sclerosis lesion segmentation: Resource and challenge.

    abstract：:In conjunction with the ISBI 2015 conference, we organized a longitudinal lesion segmentation challenge providing training and test data to registered participants. The training data consisted of five subjects with a mean of 4.4 time-points, and test data of fourteen subjects with a mean of 4.4 time-points. All 82 dat...

    journal_title：NeuroImage

    pub_type： 杂志文章

    doi：10.1016/j.neuroimage.2016.12.064

    authors： Carass A,Roy S,Jog A,Cuzzocreo JL,Magrath E,Gherman A,Button J,Nguyen J,Prados F,Sudre CH,Jorge Cardoso M,Cawley N,Ciccarelli O,Wheeler-Kingshott CAM,Ourselin S,Catanese L,Deshpande H,Maurel P,Commowick O,Barillot C

    更新日期：2017-03-01 00:00:00

  • Co-activation patterns distinguish cortical modules, their connectivity and functional differentiation.

    abstract：:The organization of the cerebral cortex into distinct modules may be described along several dimensions, most importantly, structure, connectivity and function. Identification of cortical modules by differences in whole-brain connectivity profiles derived from diffusion tensor imaging or resting state correlations has...

    journal_title：NeuroImage

    pub_type： 杂志文章

    doi：10.1016/j.neuroimage.2011.05.021

    authors： Eickhoff SB,Bzdok D,Laird AR,Roski C,Caspers S,Zilles K,Fox PT

    更新日期：2011-08-01 00:00:00

  • Diffusion kurtosis as an in vivo imaging marker for reactive astrogliosis in traumatic brain injury.

    abstract：:Diffusion Kurtosis Imaging (DKI) provides quantifiable information on the non-Gaussian behavior of water diffusion in biological tissue. Changes in water diffusion tensor imaging (DTI) parameters and DKI parameters in several white and gray matter regions were investigated in a mild controlled cortical impact (CCI) in...

    journal_title：NeuroImage

    pub_type： 杂志文章

    doi：10.1016/j.neuroimage.2011.07.050

    authors： Zhuo J,Xu S,Proctor JL,Mullins RJ,Simon JZ,Fiskum G,Gullapalli RP

    更新日期：2012-01-02 00:00:00

  • Effects of attenuation correction and reconstruction method on PET activation studies.

    abstract：:The outcome of Statistical Parametric Mapping (SPM) analyses of PET activation studies depends among others, on the quality of reconstructed data. In general, filtered back-projection (FBP) is used for reconstruction in PET activation studies. There is, however, increasing interest in iterative reconstruction algorith...

    journal_title：NeuroImage

    pub_type： 临床试验,杂志文章

    doi：10.1016/S1053-8119(03)00379-3

    authors： Mesina CT,Boellaard R,van den Heuvel OA,Veltman DJ,Jongbloed G,van der Vaart AW,Lammertsma AA

    更新日期：2003-10-01 00:00:00

  • Searching for behavior relating to grey matter volume in a-priori defined right dorsal premotor regions: Lessons learned.

    abstract：:Recently, we showed that the functional heterogeneity of the right dorsal premotor (PMd) cortex could be better understood by dividing it into five subregions that showed different behavioral associations according to task-based activations studies. The present study investigated whether the revealed behavioral profil...

    journal_title：NeuroImage

    pub_type： 杂志文章

    doi：10.1016/j.neuroimage.2017.05.053

    authors： Genon S,Wensing T,Reid A,Hoffstaedter F,Caspers S,Grefkes C,Nickl-Jockschat T,Eickhoff SB

    更新日期：2017-08-15 00:00:00

  • Focal brain matter differences associated with lifetime alcohol intake and visual attention in male but not in female non-alcohol-dependent drinkers.

    abstract：:The purpose of this study was to investigate whether current or lifetime alcohol intake is related to focal gray and white matter in healthy non-alcohol-dependent drinkers, and, if so, whether these densities are related to functional brain activity associated with visual attention. Voxel-based morphometric analyses o...

    journal_title：NeuroImage

    pub_type： 杂志文章

    doi：10.1016/j.neuroimage.2005.01.036

    authors： de Bruin EA,Hulshoff Pol HE,Schnack HG,Janssen J,Bijl S,Evans AC,Kenemans JL,Kahn RS,Verbaten MN

    更新日期：2005-06-01 00:00:00

  • Space-time-frequency analysis of EEG data using within-subject statistical tests followed by sequential PCA.

    abstract：:A new method is developed for analyzing the time-varying spectral content of EEG data collected in cognitive tasks. The goal is to extract and summarize the most salient features of numerical results, which span space, time, frequency, task conditions, and multiple subjects. Direct generalization of an established app...

    journal_title：NeuroImage

    pub_type： 杂志文章

    doi：10.1016/j.neuroimage.2008.09.020

    authors： Ferree TC,Brier MR,Hart J Jr,Kraut MA

    更新日期：2009-03-01 00:00:00

  • CLADA: cortical longitudinal atrophy detection algorithm.

    abstract：:Measurement of changes in brain cortical thickness is useful for the assessment of regional gray matter atrophy in neurodegenerative conditions. A new longitudinal method, called CLADA (cortical longitudinal atrophy detection algorithm), has been developed for the measurement of changes in cortical thickness in magnet...

    journal_title：NeuroImage

    pub_type： 杂志文章

    doi：10.1016/j.neuroimage.2010.07.052

    authors： Nakamura K,Fox R,Fisher E

    更新日期：2011-01-01 00:00:00

  • Dynamic fMRI networks predict success in a behavioral weight loss program among older adults.

    abstract：:More than one-third of adults in the United States are obese, with a higher prevalence among older adults. Obesity among older adults is a major cause of physical dysfunction, hypertension, diabetes, and coronary heart diseases. Many people who engage in lifestyle weight loss interventions fail to reach targeted goals...

    journal_title：NeuroImage

    pub_type： 杂志文章,随机对照试验

    doi：10.1016/j.neuroimage.2018.02.025

    authors： Mokhtari F,Rejeski WJ,Zhu Y,Wu G,Simpson SL,Burdette JH,Laurienti PJ

    更新日期：2018-06-01 00:00:00

  • Reward expectation modulates feedback-related negativity and EEG spectra.

    abstract：:The ability to evaluate outcomes of previous decisions is critical to adaptive decision-making. The feedback-related negativity (FRN) is an event-related potential (ERP) modulation that distinguishes losses from wins, but little is known about the effects of outcome probability on these ERP responses. Further, little ...

    journal_title：NeuroImage

    pub_type： 杂志文章

    doi：10.1016/j.neuroimage.2006.11.056

    authors： Cohen MX,Elger CE,Ranganath C

    更新日期：2007-04-01 00:00:00

  • Triple visual hemifield maps in a case of optic chiasm hypoplasia.

    abstract：:In humans, each hemisphere comprises an overlay of two visuotopic maps of the contralateral visual field, one from each eye. Is the capacity of the visual cortex limited to these two maps or are plastic mechanisms available to host more maps? We determined the cortical organization of the visual field maps in a rare i...

    journal_title：NeuroImage

    pub_type： 杂志文章

    doi：10.1016/j.neuroimage.2020.116822

    authors： Ahmadi K,Fracasso A,Puzniak RJ,Gouws AD,Yakupov R,Speck O,Kaufmann J,Pestilli F,Dumoulin SO,Morland AB,Hoffmann MB

    更新日期：2020-07-15 00:00:00

  • White matter hyperintensities are associated with subthreshold amyloid accumulation.

    abstract：:The association between white matter hyperintensities (WMH) and amyloid accumulation over time in cognitively normal, amyloid-negative elderly people remains largely unexplored. In order to study whether baseline WMH were associated with longitudinal subthreshold amyloid accumulation, 159 cognitively normal participan...

    journal_title：NeuroImage

    pub_type： 杂志文章

    doi：10.1016/j.neuroimage.2020.116944

    authors： Moscoso A,Rey-Bretal D,Silva-Rodríguez J,Aldrey JM,Cortés J,Pías-Peleteiro J,Ruibal Á,Aguiar P,Alzheimer’s Disease Neuroimaging Initiative.

    更新日期：2020-09-01 00:00:00

  • LEAP: learning embeddings for atlas propagation.

    abstract：:We propose a novel framework for the automatic propagation of a set of manually labeled brain atlases to a diverse set of images of a population of subjects. A manifold is learned from a coordinate system embedding that allows the identification of neighborhoods which contain images that are similar based on a chosen ...

    journal_title：NeuroImage

    pub_type： 杂志文章

    doi：10.1016/j.neuroimage.2009.09.069

    authors： Wolz R,Aljabar P,Hajnal JV,Hammers A,Rueckert D,Alzheimer's Disease Neuroimaging Initiative.

    更新日期：2010-01-15 00:00:00

  • Imaging brain hemodynamic changes during rat forepaw electrical stimulation using functional photoacoustic microscopy.

    abstract：:The present study reported the development of a novel functional photoacoustic microscopy (fPAM) system for investigating hemodynamic changes in rat cortical vessels associated with electrical forepaw stimulation. Imaging of blood optical absorption by fPAM at multiple appropriately-selected and distinct wavelengths c...

    journal_title：NeuroImage

    pub_type： 杂志文章

    doi：10.1016/j.neuroimage.2010.03.065

    authors： Liao LD,Li ML,Lai HY,Shih YY,Lo YC,Tsang S,Chao PC,Lin CT,Jaw FS,Chen YY

    更新日期：2010-08-15 00:00:00

  • The relationship between the visual evoked potential and the gamma band investigated by blind and semi-blind methods.

    abstract：:Gamma Band Activity (GBA) is increasingly studied for its relation with attention, change detection, maintenance of working memory and the processing of sensory stimuli. Activity around the gamma range has also been linked with early visual processing, although the relationship between this activity and the low freque...

    journal_title：NeuroImage

    pub_type： 杂志文章

    doi：10.1016/j.neuroimage.2011.03.008

    authors： Porcaro C,Ostwald D,Hadjipapas A,Barnes GR,Bagshaw AP

    更新日期：2011-06-01 00:00:00

  • Improved statistical evaluation of group differences in connectomes by screening-filtering strategy with application to study maturation of brain connections between childhood and adolescence.

    abstract：:Detecting local differences between groups of connectomes is a great challenge in neuroimaging, because the large number of tests that have to be performed and the impact on multiplicity correction. Any available information should be exploited to increase the power of detecting true between-group effects. We present ...

    journal_title：NeuroImage

    pub_type： 杂志文章

    doi：10.1016/j.neuroimage.2014.11.059

    authors： Meskaldji DE,Vasung L,Romascano D,Thiran JP,Hagmann P,Morgenthaler S,Van De Ville D

    更新日期：2015-03-01 00:00:00

  • Multivariate analysis of neuronal interactions in the generalized partial least squares framework: simulations and empirical studies.

    abstract：:Identification of spatiotemporal interactions within/between neuron populations is critical for detection and characterization of large-scale neuronal interactions underlying perception, cognition, and behavior. Univariate analysis has been employed successfully in many neuroimaging studies. However, univariate analys...

    journal_title：NeuroImage

    pub_type： 杂志文章

    doi：10.1016/S1053-8119(03)00333-1

    authors： Lin FH,McIntosh AR,Agnew JA,Eden GF,Zeffiro TA,Belliveau JW

    更新日期：2003-10-01 00:00:00