Severe haematologic toxicity is rare in high risk HIV-exposed infants receiving combination neonatal prophylaxis.

abstract：OBJECTIVES:Antiretroviral therapy has dramatically improved the survival of HIV-infected children. Nevertheless, side effects comparable to those found in adults have been encountered, such as facial lipoatrophy, which can have a negative impact on the self-esteem of otherwise healthy adolescents. Cosmetic surgical pro...

journal_title：HIV medicine

authors： Dollfus C,Blanche S,Trocme N,Funck-Brentano I,Bonnet F,Levan P

更新日期：2009-05-01 00:00:00

abstract：BACKGROUND:In the debate about legalization of euthanasia very little attention has so far been given to the opinion of the patient. OBJECTIVE:To assess the opinion of persons with HIV infection in Europe. METHODS:A cross-sectional survey of persons with HIV infection attending HIV/AIDS treatment centres or HIV suppo...

journal_title：HIV medicine

authors： Andraghetti R,Foran S,Colebunders R,Tomlinson D,Vyras P,Borleffs CJ,Fleerackers Y,Schrooten W,Borchert M

更新日期：2001-01-01 00:00:00

abstract：BACKGROUND:Highly active antiretroviral therapy (HAART) has increased longevity. Currently, women comprise >50% of HIV-infected individuals worldwide. It is not known if there are differences between the sexes in the immunological and virological responses to HAART across the age strata. METHODS:Immunological reconsti...

journal_title：HIV medicine

authors： Patterson K,Napravnik S,Eron J,Keruly J,Moore R

更新日期：2007-09-01 00:00:00

abstract：:HIV infection has become a chronic condition rather than an acute life-threatening disease in developed countries, thanks to consistent innovation and evolution of effective interventions. This has altered HIV management and created new challenges. People living with HIV (PLWHIV) are living longer and so encounter com...

journal_title：HIV medicine

authors： Antela A,Aguiar C,Compston J,Hendry BM,Boffito M,Mallon P,Pourcher-Martinez V,Di Perri G

更新日期：2016-05-01 00:00:00

abstract：OBJECTIVES:Although cognitive outcomes among perinatally infected youth have improved with highly active antiretroviral therapy (HAART), the impact of the age of initiation of treatment and the central nervous system (CNS) penetration effectiveness (CPE) of the regimen on cognitive outcomes is unknown. We aimed to desc...

journal_title：HIV medicine

authors： Lazarus JR,Rutstein RM,Lowenthal ED

更新日期：2015-07-01 00:00:00

abstract：OBJECTIVES:Adipose dysregulation, dyslipidemia, and insulin resistance are hallmarks of HIV-related lipodystrophy. The precise mechanisms behind these disturbances are unknown. In HIV-infected patients, we previously demonstrated a strong relationship between lipodystrophy and levels of adiponectin, an adipose peptide ...

journal_title：HIV medicine

authors： Sankalé JL,Tong Q,Hadigan CM,Tan G,Grinspoon SK,Kanki PJ,Hotamisligil GS

更新日期：2006-05-01 00:00:00

abstract：OBJECTIVE:The aim of the study was to compare the incidence of anaemia in patients treated with zidovudine (ZDV) with that in patients treated with highly active antiretroviral therapy (HAART) not including ZDV. METHODS:Using HIV Insight, a database of abstracted US HIV care centre medical charts, ZDV-naïve patients s...

journal_title：HIV medicine

authors： Curkendall SM,Richardson JT,Emons MF,Fisher AE,Everhard F

更新日期：2007-11-01 00:00:00

abstract：OBJECTIVES:Human leukocyte antigen (HLA)-B(*)5701 is strongly associated with developing a hypersensitivity reaction to abacavir (ABC) in White and Hispanic subjects. Across the UK, limited data exist on HLA-B(*)5701 prevalence in HIV-1-infected subjects. We determined HLA-B(*)5701 prevalence in the general HIV-1-infec...

journal_title：HIV medicine

authors： Orkin C,Sadiq ST,Rice L,Jackson F,UK EPI team.

更新日期：2010-03-01 00:00:00

abstract：OBJECTIVE:A prospective study was carried out to assess HIV-1 and HIV-2 mother-to-child transmission (MTCT) rates in Portugal between 1999 and 2005 by analysing the proportion of diagnosed infected children born to HIV-positive mothers. MATERIALS AND METHODS:Serial blood samples were collected from 1315 children at ri...

journal_title：HIV medicine

authors： Pádua E,Almeida C,Nunes B,Cortes Martins H,Castela J,Neves C,Paixão MT

更新日期：2009-03-01 00:00:00

abstract：OBJECTIVE:The aim of the study was to describe Veterans Healthcare Administration (VHA) system-wide uptake of three HIV protease inhibitors: atazanavir, darunavir and tipranavir. METHODS:This retrospective cohort study evaluated VHA uptake of three target antiretrovirals and lopinavir/ritonavir in each complete 90-day...

journal_title：HIV medicine

authors： Belperio PS,Mole LA,Boothroyd DB,Backus LI

更新日期：2010-03-01 00:00:00

abstract：OBJECTIVES:The aim of this national audit was to assess adherence of services providing HIV care in the UK to national standards and guidelines regarding psychological support and the assessment of alcohol and recreational drug use (including chemsex drugs) in people living with HIV (PLWH). METHODS:Participating sites...

journal_title：HIV medicine

authors： Parry S,Curtis H,Chadwick D,British HIV Association Audit and Standards Sub-Committee.

更新日期：2019-07-01 00:00:00

abstract：OBJECTIVES:Despite the benefits of HAART, initiation of antiretroviral therapy in HIV-HCV co-infected patients is often delayed as a consequence of patient and physician concern pertaining to liver toxicity. It is unclear whether this is justified. METHODS:We retrospectively evaluated treatment duration and outcome in...

journal_title：HIV medicine

authors： Cooper CL,Breau C,Laroche A,Lee C,Garber G

更新日期：2006-01-01 00:00:00

abstract：OBJECTIVES:In recent years, new technologies and new approaches to scale up HIV testing have emerged. The objective of this paper was to synthesize the body of recent evidence on strategies aimed at increasing the uptake and coverage of HIV testing outside of health care settings in the European Union (EU)/European Eco...

journal_title：HIV medicine

authors： Croxford S,Tavoschi L,Sullivan AK,Combs L,Raben D,Delpech V,Jakobsen SF,Amato-Gauci AJ,Desai S

更新日期：2020-03-01 00:00:00

abstract：OBJECTIVES:To audit clinical and surrogate marker outcome data following the introduction of combination antiretroviral therapy to HIV-infected children in South London. METHODS:We performed a retrospective cohort study of 110 HIV-infected children under the care of the Paediatric HIV in South London Network (PHILS-NE...

journal_title：HIV medicine

authors： Doerholt K,Sharland M,Ball C,DuMont G

更新日期：2002-01-01 00:00:00

abstract：OBJECTIVES:An article by the Swiss AIDS Commission states that patients with stably suppressed viraemia [i.e. several successive HIV-1 RNA plasma concentrations (viral loads, VL) below the limits of detection during 6 months or more of highly active antiretroviral therapy (HAART)] are unlikely to be infectious. Questio...

journal_title：HIV medicine

authors： Combescure C,Vallier N,Ledergerber B,Cavassini M,Furrer H,Rauch A,Battegay M,Bernasconi E,Vernazza P,Hirschel B,Swiss HIV Cohort Study.

更新日期：2009-09-01 00:00:00

abstract：OBJECTIVE:More and more highly treatment-experienced patients are achieving viral suppression. However, the durability of suppression remains unclear. METHODS:Patients from Royal Free Hospital (London, UK) and JW Goethe University Hospital (Frankfurt, Germany) who had failed > or = 1 antiretroviral (ARV) regimen in al...

journal_title：HIV medicine

authors： Smith CJ,Phillips AN,Dauer B,Johnson MA,Lampe FC,Youle MS,Tyrer M,Staszewski S

更新日期：2009-01-01 00:00:00

abstract：OBJECTIVES:Direct-acting antiviral agents (DAAs) have become the standard of care for the treatment of chronic hepatitis C virus (HCV) infection. We aimed to assess treatment uptake and efficacy in routine clinical settings among HIV/HCV coinfected patients after the introduction of the first generation DAAs. METHODS:...

journal_title：HIV medicine

authors： Schaerer V,Haubitz S,Kovari H,Ledergerber B,Ambrosioni J,Cavassini M,Stoeckle M,Schmid P,Decosterd L,Aouri M,Böni J,Günthard HF,Furrer H,Metzner KJ,Fehr J,Rauch A,Swiss HIV Cohort Study.

更新日期：2015-11-01 00:00:00

abstract：OBJECTIVES:The aim of the study was to investigate the prevalence of and risk factors for hepatitis C or B virus (HCV or HBV) coinfection among HIV-infected pregnant women, and to investigate their immunological and virological characteristics and antiretroviral therapy use. METHODS:Information on HBV surface antigen ...

journal_title：HIV medicine

authors： Landes M,Newell ML,Barlow P,Fiore S,Malyuta R,Martinelli P,Posokhova S,Savasi V,Semenenko I,Stelmah A,Tibaldi C,Thorne C

更新日期：2008-08-01 00:00:00

abstract：OBJECTIVES:The aim of the study was to investigate HIV testing practice among female sex workers (FSWs) and men who have sex with men (MSM) in Tbilisi, Georgia and to identify determinants of never testing behaviour among MSM. METHODS:Data obtained in two rounds of bio-behavioural surveys among FSWs (2006 and 2009) an...

journal_title：HIV medicine

authors： Tsereteli N,Chikovani I,Chkhaidze N,Goguadze K,Shengelia N,Rukhadze N

更新日期：2013-10-01 00:00:00

abstract：OBJECTIVES:We assessed whether changes at week 12 in markers of bone turnover, inflammation, and immune activation were associated with clinically important (≥ 5%) bone mineral density (BMD) loss from baseline to week 48 at the proximal femur (hip) and lumbar spine in the SECOND-LINE study. METHODS:We measured concent...

journal_title：HIV medicine

authors： Mwasakifwa GE,Amin J,White CP,Center JR,Kelleher A,Boyd MA

更新日期：2020-09-01 00:00:00

abstract：OBJECTIVES:Despite the huge success of antiretroviral therapy (ART), there is an ongoing HIV epidemic among men who have sex with men (MSM) in resource-rich countries. Understanding the driving factors underlying this process is important for curbing the epidemic. METHODS:We simulated the HIV epidemic in MSM in Switze...

journal_title：HIV medicine

authors： Kusejko K,Marzel A,Hampel B,Bachmann N,Nguyen H,Fehr J,Braun DL,Battegay M,Bernasconi E,Calmy A,Cavassini M,Hoffmann M,Böni J,Yerly S,Klimkait T,Perreau M,Rauch A,Günthard HF,Kouyos RD,Swiss HIV Cohort Study.

更新日期：2018-11-01 00:00:00

abstract：OBJECTIVE:Study 903 was a 144-week, randomized, double-blind, active-controlled study of tenofovir disoproxil fumarate (TDF) therapy in treatment-naive HIV-1-infected patients. Patients received either TDF (n = 299) or stavudine (d4T) (n = 301) with lamivudine (3TC) and efavirenz (EFV). Resistance analyses were perform...

journal_title：HIV medicine

authors： Margot NA,Lu B,Cheng A,Miller MD,Study 903 Team.

更新日期：2006-10-01 00:00:00

abstract：:The advent of potent highly active antiretroviral therapy (HAART) for persons infected with HIV-1 has led to a "new" chronic disease with complications including cardiovascular disease (CVD). CVD is a significant cause of morbidity and mortality in persons with HIV infection. In addition to traditional risk factors su...

journal_title：HIV medicine

authors： Lambert CT,Sandesara PB,Hirsh B,Shaw LJ,Lewis W,Quyyumi AA,Schinazi RF,Post WS,Sperling L

更新日期：2016-06-01 00:00:00

abstract：OBJECTIVES:The aims of the present study were to estimate the prevalence of renal impairment (RI) among HIV-infected adult patients and to investigate the associated factors. METHODS:A cross-sectional survey was conducted in a French hospital-based cohort. Clearance of creatinine (CC) was calculated using the Cockcrof...

journal_title：HIV medicine

authors： Déti EK,Thiébaut R,Bonnet F,Lawson-Ayayi S,Dupon M,Neau D,Pellegrin JL,Malvy D,Tchamgoué S,Dabis F,Morlat P,Groupe d'Epidémiologie Clinique du SIDA en Aquitaine.

更新日期：2010-05-01 00:00:00

abstract：OBJECTIVES:Dyslipidaemia has become a common problem in HIV disease, especially in patients on current antiretroviral therapy. However, the pathogenic mechanisms involved are not well understood or documented using conventional lipid measurements. METHODS:Using a cross-sectional design, the prevalence of abnormal stan...

journal_title：HIV medicine

authors： Rimland D,Guest JL,Hernández I,Del Rio C,Le NA,Brown WV

更新日期：2005-09-01 00:00:00

abstract：OBJECTIVES:In most lung screening programmes, only subjects ≥ 55 years old and smoking ≥ 30 pack-years are eligible to undergo chest low-dose computed tomography. Whether the same criteria should apply to people living with HIV (PLHIV) is uncertain, given the increased lung cancer risks associated with immunodeficiency...

journal_title：HIV medicine

authors： Makinson A,Tron L,Grabar S,Milleron B,Reynes J,Le Moing V,Morquin D,Lert F,Costagliola D,Guiguet M

更新日期：2020-03-01 00:00:00

abstract：OBJECTIVES:Three-drug nonoccupational post-exposure prophylaxis (NPEP) typically includes co-formulated emtricitabine-tenofovir (FTC-TDF) and a protease inhibitor. However, protease inhibitors can cause significant toxicities, can interact with prescribed and illicit drugs, and work late in the viral cycle. Agents that...

journal_title：HIV medicine

authors： McAllister J,Read P,McNulty A,Tong WW,Ingersoll A,Carr A

更新日期：2014-01-01 00:00:00

abstract：OBJECTIVES:To compare the safety and efficacy of amprenavir [APV/j Agenerase trade mark; GlaxoSmithKline, [Ware, UK; 600 mg twice a day (bid)] boosted with low-dose ritonavir (RTV, 100 mg bid) with those of other protease inhibitors (PIs) in PI-experienced HIV-infected patients. STUDY DESIGN:Parallel-group, randomized...

journal_title：HIV medicine

authors： Pulido F,Katlama C,Marquez M,Thomas R,Clumeck N,Pedro Rde J,Cattelan AM,Zhu C,Tymkewycz P

更新日期：2004-07-01 00:00:00

abstract：OBJECTIVE:To compare virological and immunological responses to nevirapine (NVP)-based and efavirenz (EFV)-based highly active antiretroviral therapy (HAART) regimens in antiretroviral-naïve patients with advanced HIV infection. METHODS:A retrospective observational cohort study was conducted on antiretroviral-naïve H...

journal_title：HIV medicine

authors： Manosuthi W,Sungkanuparph S,Vibhagool A,Rattanasiri S,Thakkinstian A

更新日期：2004-03-01 00:00:00

abstract：:Despite advances in the treatment of HIV disease, the incidence and mortality of invasive cryptococcal disease remain significant. A matched, case-control study was performed to examine the impact of highly active antiretroviral therapy (HAART) and azole use on the incidence of invasive cryptococcal disease in HIV-inf...

journal_title：HIV medicine

authors： Cantey PT,Stephens DS,Rimland D

更新日期：2005-07-01 00:00:00