Abstract:
:A team of experts from the fields of gynaecology and obstetrics, diabetology, internal medicine, paediatrics and midwifery from Germany, Austria and Switzerland produced a new version of the existing S3 guideline on gestational diabetes. It replaces the recommendations of the German Association for Gynaecology and Obstetrics and the German Diabetes Association on the diagnosis and treatment of gestational diabetes from 2011 and is valid for the three German-speaking countries. The primary aim of the guideline is to improve and standardise the prevention, screening, diagnosis, treatment and follow-up of gestational diabetes through evidence-based recommendations for the outpatient and inpatient area. A large number of new studies and data published in the last few years required a comprehensive revision of the 2011 guideline. The new aspects include early screening of pregnant women with a high risk for diabetes or gestational diabetes, the validity of two-stage screening in the third trimester by means of the 50-g challenge test, as specified in the maternity guidelines, use of metformin instead of or in addition to insulin in gestational diabetes, and birth planning with GDM and/or macrosomia. The recommendations are based on the evidence from the literature, which was selected through a systematic external literature search. All recommendations had to pass through a consensus process. The present text corresponds to the practice guideline on gestational diabetes, which is an action-oriented short version of the evidence-based S3 guideline that can be viewed on the internet. :Ein Expertenteam aus dem Bereich der Gynäkologie und Geburtshilfe, Diabetologie, Innere Medizin, Kinderheilkunde und Hebammenwissenschaften aus Deutschland, Österreich und Schweiz erstellte eine neue Version der bestehenden S3-Leitlinie zum Gestationsdiabetes. Sie ersetzt die Empfehlungen der Deutschen Gesellschaft für Gynäkologie und Geburtshilfe und der Deutschen Diabetesgesellschaft zur Diagnostik und Therapie des Gestationsdiabetes aus dem Jahr 2011 und ist für die 3 deutschsprachigen Länder gültig. Primäres Ziel der Leitlinie ist die Verbesserung und Vereinheitlichung von Prävention, Screening, Diagnostik, Therapie und Nachsorge bei Gestationsdiabetes durch evidenzbasierte Empfehlungen für den ambulanten und stationären Bereich. Eine Vielzahl von Veröffentlichungen neuer Studien und Daten der letzten Jahre erforderte eine umfassende Überarbeitung der Leitlinie von 2011. Die neuen Aspekte betreffen u. a. das Frühscreening bei Schwangeren mit hohem Risiko für Diabetes oder Gestationsdiabetes, die Validität des 2-stufigen Screenings im 3. Trimenon mittels 50-g-Suchtest, wie es in den Mutterschaftsrichtlinien vorgeschrieben ist, die Gabe von Metformin statt oder in Ergänzung zu Insulin bei Gestationsdiabetes und die Geburtsplanung bei GDM und/oder Makrosomie. Die Empfehlungen basieren auf der Evidenz, die sich aus der Literatur ergibt, deren Auswahl über eine systematische, externe Literatursuche erfolgte. Alle Empfehlungen mussten einen Konsensus-Prozess durchlaufen. Der vorliegende Text entspricht der Praxisleitlinie zum Gestationsdiabetes, die eine handlungsorientierte Kurzfassung der im Internet einsehbaren evidenzbasierten S3-Leitlinie ist.
journal_name
Geburtshilfe Frauenheilkdjournal_title
Geburtshilfe und Frauenheilkundeauthors
Schäfer-Graf UM,Gembruch U,Kainer F,Groten T,Hummel S,Hösli I,Grieshop M,Kaltheuner M,Bührer C,Kautzky-Willer A,Laubner K,Bancher-Todesca Ddoi
10.1055/a-0659-2596subject
Has Abstractpub_date
2018-12-01 00:00:00pages
1219-1231issue
12eissn
0016-5751issn
1438-8804pii
6592596journal_volume
78pub_type
杂志文章abstract::In invasive carcinoma of the cervix stage 1B our investigations showed 19% lymph node metastases (n = 47) which were verified by operation and microscopic examination. In all of these patients no lympographic evidence of metastases was observed. The value of lymphography in stage 1B invasive carcinoma of the cervix is...
journal_title:Geburtshilfe und Frauenheilkunde
pub_type: 杂志文章
doi:
更新日期:1979-04-01 00:00:00
abstract::Twin delivery is often complicated by breech presentation of the second twin. To investigate the influence of breech presentation of the second twin, we reviewed all 259 twin deliveries from the 18,404 deliveries at our institution over 11 years between 1978 to 1989. The neonatal morbidity of the second twin in breech...
journal_title:Geburtshilfe und Frauenheilkunde
pub_type: 杂志文章
doi:10.1055/s-2008-1026381
更新日期:1990-11-01 00:00:00
abstract::Anosmia and primary amenorrhoea are guiding symptoms of Kallmann's syndrome (olfacto-genital syndrome) in which agenesis of the olfactory lobe is associated with congenital defects in the mediobasal region of the hypothalamus, thus preventing a sufficient GnRH synthesis. In three patients with Kallmann's syndrome, the...
journal_title:Geburtshilfe und Frauenheilkunde
pub_type: 杂志文章
doi:10.1055/s-2008-1036627
更新日期:1983-06-01 00:00:00
abstract::Contaminants exercise an influence on different levels of reproduction, resulting in disturbances of the cycle, abortion and diverse complications during pregnancy among women, whereas, in the case of men, alterations of the spermiogram have been observed. Numerous unfavourable influences on reproduction are known fro...
journal_title:Geburtshilfe und Frauenheilkunde
pub_type: 杂志文章,评审
doi:10.1055/s-2007-1023171
更新日期:1992-09-01 00:00:00
abstract::In a retrospective study the mode of delivery by 565 pregnant women who had previously undergone Caesarean section, was explored on the basis of their medical records. Particular attention was paid to the problem of PDA. Primary Caesarean section was performed in about 25% of the cases and secondary Caesarean section ...
journal_title:Geburtshilfe und Frauenheilkunde
pub_type: 杂志文章
doi:10.1055/s-2008-1036868
更新日期:1984-03-01 00:00:00
abstract::Three million out of 4.5 million foreigners in Germany are from countries, where sickle cell anaemia is found. Today, this disease occurs in Germany with sufficient frequency and this makes it imperative for every physician to be familiar with it. Most of the sickle cell patients today attain the reproductive age. Dur...
journal_title:Geburtshilfe und Frauenheilkunde
pub_type: 杂志文章,评审
doi:10.1055/s-2008-1026275
更新日期:1990-06-01 00:00:00
abstract::100 specimens of patients with primary node-negative breast cancer were examined by flow cytometry. 64 tumours were shown to be diploid and 36 tumours were aneuploid. The median was the cut-off level for tumours with low S-phase (< or = 10.9%) and high S-phase values (> 10.9%). Aneuploid tumours were associated with h...
journal_title:Geburtshilfe und Frauenheilkunde
pub_type: 杂志文章
doi:10.1055/s-2007-1022842
更新日期:1994-05-01 00:00:00
abstract::There is a well-known correlation between ascending infection and preterm labour. Nevertheless, up to now an exact method to identify patients which are at high risk for preterm labour does not exist. Fetal fibronectin is an extracellular matrix protein, which is produced by fetal membranes. High concentrations are pr...
journal_title:Geburtshilfe und Frauenheilkunde
pub_type: 临床试验,杂志文章
doi:10.1055/s-2007-1023624
更新日期:1994-12-01 00:00:00
abstract::In 49 carcinomas of the endometrium of varying clinical stages the estrogen and progesterone receptors were studied by charcoal absorption methods. The cases were studied between 1979 and 1981. 64% of the investigated cases were receptor positive, 35% were receptor negative. Estrogen receptors were detected in 61% and...
journal_title:Geburtshilfe und Frauenheilkunde
pub_type: 杂志文章
doi:10.1055/s-2008-1037179
更新日期:1982-12-01 00:00:00
abstract::65 microcarcinomas and 189 Ca. in situ-cases were diagnosed by cone biopsy in the Department of Gynaecology and Obstetrics of the University in Kiel in the periods 1973-1976 and 1977-1980. During the first period the haemostasis of the conization crater was obtained by the conventional techniques. In 38% (microcarcino...
journal_title:Geburtshilfe und Frauenheilkunde
pub_type: 杂志文章
doi:10.1055/s-2008-1036799
更新日期:1982-06-01 00:00:00
abstract::368 urodynamically investigated women of the University Hospital of Innsbruck (Austria) were separated into four groups depending on their incontinence status (either stress incontinence or not) and depending on previous incontinence surgery. In this collective of patients, we compared the urethral length, the absolut...
journal_title:Geburtshilfe und Frauenheilkunde
pub_type: 杂志文章
doi:10.1055/s-2008-1036102
更新日期:1989-10-01 00:00:00
abstract::Relevant correlations between the level of the IQ and the reactions to gynaecological interventions and changes in the female reproductive system were detected. These are important in medical practice. The findings are based on psychometric studies in 400 to 500 women. First: Puberty and menarche are experienced in co...
journal_title:Geburtshilfe und Frauenheilkunde
pub_type: 杂志文章
doi:
更新日期:1978-08-01 00:00:00
abstract::Various legal aspects of voluntary sterilization in West Germany are discussed. Legal precedents have established the right of any person over 25 to undergo voluntary sterilization; those under 25 may undergo sterilization only in the case of a medical, genetic, or criminological indication. The German Physicians' C...
journal_title:Geburtshilfe und Frauenheilkunde
pub_type: 杂志文章
doi:
更新日期:1978-08-01 00:00:00
abstract::The article reports on a clinically unusual case of a patient with carcinoma of the breast. The "initial sign" of the disease was relapsed hypermenorrhoic permanent bleeding with severe bleeding anaemia caused by a metastatic growth in the uterus. Surgery or cytostatic treatment did not seem possible at the outset, be...
journal_title:Geburtshilfe und Frauenheilkunde
pub_type: 杂志文章
doi:10.1055/s-2008-1036468
更新日期:1985-05-01 00:00:00
abstract::The information available about breast cancer risk factors has increased dramatically during the last 10 years. In particular, studies of low-penetrance genes and mammographic density have improved our understanding of breast cancer risk. In addition, initial steps have been taken in investigating interactions between...
journal_title:Geburtshilfe und Frauenheilkunde
pub_type: 杂志文章
doi:10.1055/s-0031-1280437
更新日期:2011-12-01 00:00:00
abstract::133 patients attending the colposcopy-laser outpatient consultations were examined simultaneously by cytology, colposcopy and punch biopsy. A cone biopsy was taken 25 patients and one patient was hysterectomised later. A comparison between cytology and histology revealed 17.1% false negative smear results. Cytology an...
journal_title:Geburtshilfe und Frauenheilkunde
pub_type: 杂志文章
doi:10.1055/s-2007-1022864
更新日期:1994-07-01 00:00:00
abstract::The introduction of percutaneous nephrostomy under xc-ray control or ultra-sonic control makes it possible to do the operation even in patients with a bad general condition. The decision for palliative urinary diversion in cases of cancer of the pelvis is therefore largely an ethical question. A group of patients with...
journal_title:Geburtshilfe und Frauenheilkunde
pub_type: 杂志文章
doi:10.1055/s-2008-1037150
更新日期:1982-10-01 00:00:00
abstract::Following differentiated endocrinologic-gynecologic diagnosis auricular acupuncture was used in 15 women with oligoamenorrhea and 12 women with luteal body insufficiency who had come for hormone consultation because of sterility. In both groups the subsequent incidence of pregnancy was comparable to that achieved by d...
journal_title:Geburtshilfe und Frauenheilkunde
pub_type: 杂志文章
doi:10.1055/s-2008-1035717
更新日期:1988-03-01 00:00:00
abstract::A report on the result of a representative survey of family planning behavior in the Federal Republic of Germany in 1985. Interviewers from the EMNID Institute questioned 1267 German women aged between 15 and 45. Of the women interviewed, 6.1% had been sterilized, while in 1.3% of cases, their partner had been sterili...
journal_title:Geburtshilfe und Frauenheilkunde
pub_type: 杂志文章
doi:10.1055/s-2008-1036340
更新日期:1986-12-01 00:00:00
abstract::Background During cancer therapy, many patients suffer from malnutrition or vitamin deficiency. Treatment for nutrition-related deficiencies should therefore include nutritional therapy and possibly oral or intravenous substitution of micronutrients. Little information exists on multinutrient infusion therapies. The a...
journal_title:Geburtshilfe und Frauenheilkunde
pub_type: 杂志文章
doi:10.1055/a-0754-2923
更新日期:2018-11-01 00:00:00
abstract::We investigated the clinical course in 35 healthy newborn with premature beats and studied the literature with regard to their frequency, pathogenesis, and therapy with the following results: Investigations with continuous monitoring or long-term ECG registration show a frequency of 7-25%. In literature, almost one-fo...
journal_title:Geburtshilfe und Frauenheilkunde
pub_type: 杂志文章
doi:10.1055/s-2008-1036652
更新日期:1985-11-01 00:00:00
abstract::This study investigates the possibilities to treat oligo-asthenozoospermia, a cause of sterility, by assisted conjugation. After completing acrosome reaction, normal motile spermatozoa are microinjected into mouse oocytes. After 2 hours of incubation time in medium with lactate and albumins, spermatozoa are put into d...
journal_title:Geburtshilfe und Frauenheilkunde
pub_type: 杂志文章
doi:10.1055/s-2008-1026552
更新日期:1988-09-01 00:00:00
abstract::Subcutaneous mastectomy was performed in 335 patients between 1974 and 1982. In 265 of these, original mammographies were available which were analysed retrospectively and compared with the final histological finding of the subcutaneous mastectomy preparation. The rate of newly discovered non-invasive carcinomas in th...
journal_title:Geburtshilfe und Frauenheilkunde
pub_type: 杂志文章
doi:10.1055/s-2008-1036377
更新日期:1985-09-01 00:00:00
abstract::Introduction PCOS is the most common endocrine syndrome in women of the reproductive age that has manifold effects on the life of affected women. Little scientific attention has been devoted to these women's sexual lives. Aim To investigate sexual quality of life in women with PCOS. Methods The sample size was n = 44....
journal_title:Geburtshilfe und Frauenheilkunde
pub_type: 杂志文章
doi:10.1055/a-0828-7901
更新日期:2019-05-01 00:00:00
abstract::The foetal outcome was examined in 24 pregnant females with EPH gestosis and a placental weight below the 20th percentile. The results show a high perinatal mortality in such cases. 11 newborns with a mean birth weight of 1092 g and a mean gestational age of 33.8 weeks died perinatally versus 13 newborns with a mean b...
journal_title:Geburtshilfe und Frauenheilkunde
pub_type: 杂志文章
doi:10.1055/s-2008-1035919
更新日期:1986-05-01 00:00:00
abstract::From 1977-1989, 298 ectopic pregnancies were treated pelviscopically at the Dept. of Gynaecology Hospital of the University of Kiel. 26 tubes were already ruptured. In 251 patients (84%), organ preserving treatment was possible, 205 treatment by longitudinal salpingotomy. 46 tubal abortions were extracted. In 47 patie...
journal_title:Geburtshilfe und Frauenheilkunde
pub_type: 杂志文章
doi:10.1055/s-2007-1026197
更新日期:1991-07-01 00:00:00
abstract::More than ten years ago, the German Consortium for Hereditary Breast and Ovarian Cancer (GC-HBOC) set up a panel of experts (VUS Task Force) which was tasked with reviewing the classifications of genetic variants reported by individual centres of the GC-HBOC to the central database in Leipzig and reclassifying them, w...
journal_title:Geburtshilfe und Frauenheilkunde
pub_type: 杂志文章
doi:10.1055/a-1110-0909
更新日期:2020-04-01 00:00:00
abstract::Malignant tumours can be differentiated from the benign ones by their vascular blood supply. We employed three methods to analyse the blood flow: the angiodynograph, the duplex system, and the continuous-wave Doppler method, and measured the blood flow in 151 patients on the preoperative day. Histology revealed a mali...
journal_title:Geburtshilfe und Frauenheilkunde
pub_type: 杂志文章
doi:10.1055/s-2007-1023775
更新日期:1992-07-01 00:00:00
abstract::In the near future, important translational questions of clinical relevance will be adressed by studies currently in progress. On the one hand, the role of PD-L1 expression must be further understood, after it was found to be relevant in the use of atezolizumab in first-line therapy of patients with metastatic triple-...
journal_title:Geburtshilfe und Frauenheilkunde
pub_type: 杂志文章
doi:10.1055/a-1039-4458
更新日期:2019-12-01 00:00:00
abstract::The group around Prof. D. I. Golowin (Leningrad) distinguishes between the solid epithelial hyperplasia belonging to fibroadenomatosis of the breast and the solid form of lobular carcinoma in situ. The morphological details permitting the differential diagnosis are stressed (see table). ...
journal_title:Geburtshilfe und Frauenheilkunde
pub_type: 杂志文章
doi:
更新日期:1975-06-01 00:00:00