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Oral absorption of cephalosporin antibiotics. 3. Synthesis and biological properties of 7 alpha-methoxy-7 beta-(arylacetamido)-3-chloro-3-cephem-4- carboxylic acids.

Abstract：

:A series of 7 alpha-methoxy-7 beta-amido-3-chloro-3-cephem-4-carboxylic acids was prepared and evaluated for biological activity. When compared with the parent 7-non-methoxy analogues, these new 7 alpha-methoxy-3-chloro cephalosporins displayed diminished antimicrobial activity.

journal_name

J Med Chem

journal_title

Journal of medicinal chemistry

authors

Pfeil-Doyle J,Kukolja S

doi

10.1021/jm00118a024

subject

Has Abstract

pub_date

1988-10-01 00:00:00

pages

1997-2000

issue

10

eissn

0022-2623

issn

1520-4804

journal_volume

31

pub_type

杂志文章

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