Presence of Candida spp. and candidiasis in liver transplant patients.

Abstract:

BACKGROUND:Candidiasis is the most common opportunistic fungal infection of the oral cavity caused by fungi of the genus Candida and usually associated with immunosuppressed individuals. OBJECTIVES:To evaluate the presence of oral candidiasis and identify the presence of Candida spp. in liver transplant recipients and assess the association between the presence of the fungus and sociodemographic variables, dietary habits and environmental exposure. METHODS:A cross-sectional study was performed with 49 patients who had undergone liver transplants at Hospital São Vicente de Paulo in Passo Fundo - RS. Patient information was collected to obtain sociodemographic data, eating habits and environmental exposure. Fungal infections were screened by oral clinical examination and the presence of Candida spp by the collection of oral samples with a sterile swab, seeded in Sabouraud Dextrose Agar, incubated at 25°C and observed at 48 hours. To identify Candida albicans, the germ tube test was performed. RESULTS:In 49 patient samples, 39% had the yeast of the genus Candida isolated and, of these patients, 12% had candidiasis, 66% of atrophic type and 34% pseudomembranous. Eleven yeast species were (58%) Candida non-albicans and eight (42%) Candida albicans. STUDY LIMITATIONS:The present study presents as a limitation the inclusion of patients in different stages of immunosuppression. CONCLUSION:The high incidence of Candida non-albicans in the oral cavity of transplant patients with a long period of transplantation is warning to a more effective control of the health of these individuals, especially those with older age.

journal_name

An Bras Dermatol

authors

Santos SBD,Sabadin CES,Mario DN,Rigo L,Barbosa DA

doi

10.1590/abd1806-4841.20186533

subject

Has Abstract

pub_date

2018-06-01 00:00:00

pages

356-361

issue

3

eissn

0365-0596

issn

1806-4841

pii

S0365-05962018000300356

journal_volume

93

pub_type

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