Abstract:
:Estimating the depth of anaesthesia (DoA) in operations has always been a challenging issue due to the underlying complexity of the brain mechanisms. Electroencephalogram (EEG) signals are undoubtedly the most widely used signals for measuring DoA. In this paper, a novel EEG-based index is proposed to evaluate DoA for 24 patients receiving general anaesthesia with different levels of unconsciousness. Sample Entropy (SampEn) algorithm was utilised in order to acquire the chaotic features of the signals. After calculating the SampEn from the EEG signals, Random Forest was utilised for developing learning regression models with Bispectral index (BIS) as the target. Correlation coefficient, mean absolute error, and area under the curve (AUC) were used to verify the perioperative performance of the proposed method. Validation comparisons with typical nonstationary signal analysis methods (i.e., recurrence analysis and permutation entropy) and regression methods (i.e., neural network and support vector machine) were conducted. To further verify the accuracy and validity of the proposed methodology, the data is divided into four unconsciousness-level groups on the basis of BIS levels. Subsequently, analysis of variance (ANOVA) was applied to the corresponding index (i.e., regression output). Results indicate that the correlation coefficient improved to 0.72 ± 0.09 after filtering and to 0.90 ± 0.05 after regression from the initial values of 0.51 ± 0.17. Similarly, the final mean absolute error dramatically declined to 5.22 ± 2.12. In addition, the ultimate AUC increased to 0.98 ± 0.02, and the ANOVA analysis indicates that each of the four groups of different anaesthetic levels demonstrated significant difference from the nearest levels. Furthermore, the Random Forest output was extensively linear in relation to BIS, thus with better DoA prediction accuracy. In conclusion, the proposed method provides a concrete basis for monitoring patients' anaesthetic level during surgeries.
journal_name
PeerJjournal_title
PeerJauthors
Liu Q,Ma L,Fan SZ,Abbod MF,Shieh JSdoi
10.7717/peerj.4817subject
Has Abstractpub_date
2018-05-23 00:00:00pages
e4817issn
2167-8359pii
4817journal_volume
6pub_type
杂志文章相关文献
PeerJ文献大全abstract::Background. There has been a continual increase in injury rates in cricket, with hamstring strain injuries (HSIs) being the most prominent. Eccentric knee flexor weakness and bilateral asymmetries are major modifiable risk factors for future HSIs. However, there is a lack of data relating to eccentric hamstring streng...
journal_title:PeerJ
pub_type: 杂志文章
doi:10.7717/peerj.1594
更新日期:2016-02-18 00:00:00
abstract:Background:Among Buddhist or Taoist Taiwanese residents, burning incense is a common source of indoor particulate matter (PM), including PM10 and PM2.5, and can adversely affect the health status of patients with chronic obstructive pulmonary diseases (COPD). However, few studies have focused on the effects of intermit...
journal_title:PeerJ
pub_type: 杂志文章
doi:10.7717/peerj.9768
更新日期:2020-08-31 00:00:00
abstract::Non-invasive measurements of glucocorticoid (GC) concentrations, including cortisol and corticosterone, serve as reliable indicators of adrenocortical activities and physiological stress loads in a variety of species. As an alternative to invasive analyses based on plasma, GC concentrations in saliva still represent s...
journal_title:PeerJ
pub_type: 杂志文章
doi:10.7717/peerj.1590
更新日期:2016-01-18 00:00:00
abstract:Background:Saber-toothed mammals, now all extinct, were cats or "cat-like" forms with enlarged, blade-like upper canines, proposed as specialists in taking large prey. During the last 66 Ma, the saber-tooth ecomorph has evolved convergently at least in five different mammalian lineages across both marsupials and placen...
journal_title:PeerJ
pub_type: 杂志文章
doi:10.7717/peerj.9346
更新日期:2020-06-26 00:00:00
abstract::Automatic species classification of birds from their sound is a computational tool of increasing importance in ecology, conservation monitoring and vocal communication studies. To make classification useful in practice, it is crucial to improve its accuracy while ensuring that it can run at big data scales. Many appro...
journal_title:PeerJ
pub_type: 杂志文章
doi:10.7717/peerj.488
更新日期:2014-07-17 00:00:00
abstract:Background:A virus-like particle (VLP) is an excellent tool for a compound delivery system due to its simple composition, symmetrical structure and self-assembly. Its surface modification both chemically and genetically is established, leading to the target-specific delivery and improved encapsulation efficiency. Howev...
journal_title:PeerJ
pub_type: 杂志文章
doi:10.7717/peerj.6079
更新日期:2018-12-18 00:00:00
abstract:Background:Mangroves are important coastal ecosystems known for high photosynthetic productivity and the ability to support marine food chains through supply of dissolved carbon or particular organic matter. Most of the carbon found in mangroves is produced by its vegetation and is decomposed in root associated sedimen...
journal_title:PeerJ
pub_type: 杂志文章
doi:10.7717/peerj.5710
更新日期:2018-10-04 00:00:00
abstract::Ocean acidification (OA) is not an isolated threat, but acts in concert with other impacts on ecosystems and species. Coastal marine invertebrates will have to face the synergistic interactions of OA with other global and local stressors. One local factor, common in coastal environments, is trace element contamination...
journal_title:PeerJ
pub_type: 杂志文章
doi:10.7717/peerj.538
更新日期:2014-09-09 00:00:00
abstract::A prolonged preservation duration of blood specimens at 4 °C may occur due to the distance from collection points to storage facilities in many biobanks, especially for multicenter studies. This could lead to RNA degradation, affecting downstream analyses. However, effects of preservation durations at 4 °C on RNA qual...
journal_title:PeerJ
pub_type: 杂志文章
doi:10.7717/peerj.8940
更新日期:2020-04-10 00:00:00
abstract::[This corrects the article DOI: 10.7717/peerj.4029.]. ...
journal_title:PeerJ
pub_type: 杂志文章,已发布勘误
doi:10.7717/peerj.4029/correction-1
更新日期:2018-02-27 00:00:00
abstract:Background:Immunoglobulin superfamily member 10 (IGSF10) is a member of the immunoglobulin superfamily that is expressed at high levels in both the gallbladder and ovary. Currently, the role and possible mechanism of IGSF10 in breast cancer remain unclear. Method:By applying real-time quantitative polymerase chain rea...
journal_title:PeerJ
pub_type: 杂志文章
doi:10.7717/peerj.10128
更新日期:2020-10-21 00:00:00
abstract::Background. Low molecular weight heparin (LMWH) is an effective anti-coagulant for thrombotic events. However, due to its predominant renal clearance, there are concerns that it might be associated with increased bleeding in patients with renal disease. Objectives. We systematically evaluated the efficacy and safety o...
journal_title:PeerJ
pub_type: 杂志文章,评审
doi:10.7717/peerj.835
更新日期:2015-03-10 00:00:00
abstract:Background:"Quantile-dependent expressivity" occurs when the effect size of a genetic variant depends upon whether the phenotype (e.g. adiponectin) is high or low relative to its distribution. We have previously shown that the heritability (h2 ) of adiposity, lipoproteins, postprandial lipemia, pulmonary function, and ...
journal_title:PeerJ
pub_type: 杂志文章
doi:10.7717/peerj.10099
更新日期:2020-10-14 00:00:00
abstract:Background:The aim of the study was to evaluate the treatment outcomes of endoscopic prelacrimal recess approaches (EPLAs) in managing different sinus pathologies, analyzing associated adverse events and post-treatment quality-of-life. Methods:We enrolled 21 consecutive patients (22 lesions) who received endoscopic si...
journal_title:PeerJ
pub_type: 杂志文章
doi:10.7717/peerj.8331
更新日期:2020-01-03 00:00:00
abstract::Mechanisms generating and maintaining biodiversity at regional scales may be evaluated by quantifying β-diversity along environmental gradients. Differences in assemblages result in biotic complementarities and redundancies among sites, which may be quantified through multi-dimensional approaches incorporating taxonom...
journal_title:PeerJ
pub_type: 杂志文章
doi:10.7717/peerj.5628
更新日期:2018-09-24 00:00:00
abstract:BACKGROUND:Sturnira is one of the most species-rich genera in the Neotropics, and it is found from Mexico and the Lesser Antilles to Argentina. This genus forms a well-supported monophyletic clade with at least twenty-one recognized species, as well as several others under taxonomic review. Sturnira parvidens is a wide...
journal_title:PeerJ
pub_type: 杂志文章
doi:10.7717/peerj.3367
更新日期:2017-05-24 00:00:00
abstract::Chronostratigraphic correlation of terrestrial Early Cretaceous biotas in China is highly problematic due to the lack of marine deposits, few absolute dates, and limited number of index fossils. This often leaves vertebrate faunas as one of the few potential tools for a preliminary biostratigraphy. Taxonomic identity ...
journal_title:PeerJ
pub_type: 杂志文章
doi:10.7717/peerj.6229
更新日期:2019-01-15 00:00:00
abstract::Vitiligo is a chronic asymptomatic disorder affecting melanocytes from the basal layer of the epidermis which leads to a patchy loss of skin color. Even though it is one of the neglected disease conditions, people suffering from vitiligo are more prone to psychological disorders. As of now, various studies have been d...
journal_title:PeerJ
pub_type: 杂志文章
doi:10.7717/peerj.9119
更新日期:2020-05-21 00:00:00
abstract::A wide range of biotic stresses (BS) and abiotic stresses (AS) adversely affect plant growth and productivity worldwide. The study of individual genes cannot be considered as an effective approach for the understanding of tolerance mechanisms, since these stresses are frequent and often in combination with each other,...
journal_title:PeerJ
pub_type: 杂志文章
doi:10.7717/peerj.4631
更新日期:2018-07-17 00:00:00
abstract::[This corrects the article DOI: 10.7717/peerj.2869.]. ...
journal_title:PeerJ
pub_type: 杂志文章,已发布勘误
doi:10.7717/peerj.2869/correction-1
更新日期:2017-12-07 00:00:00
abstract:Background/Aims:Medical and behavioral needs are relevant in organizing and providing support strategies that improve the quality of life for children, along with their families. The present study aims to examine the impact of medical and behavioral needs on the need for support of children with disabilities. Methods:...
journal_title:PeerJ
pub_type: 杂志文章
doi:10.7717/peerj.9557
更新日期:2020-09-15 00:00:00
abstract::The Natural Mortality coefficient (M) is a key parameter for stock assessments. The need to establish age-specific natural mortality coefficients is widely recognized because M decreases rapidly over the early stages of the life cycle until it reaches a stable M value around the age-at-maturity. The aim of this study ...
journal_title:PeerJ
pub_type: 杂志文章
doi:10.7717/peerj.5235
更新日期:2018-07-18 00:00:00
abstract:Background:Due to intensive sluice construction and other human disturbances, lakeshore vegetation has been destroyed and ecosystems greatly changed. Rhizospheric microbiota constitute a key part of a functioning rhizosphere ecosystem. Maintaining rhizosphere microbial diversity is a central, critical issue for sustain...
journal_title:PeerJ
pub_type: 杂志文章
doi:10.7717/peerj.10078
更新日期:2020-09-29 00:00:00
abstract:Background:In idiopathic sudden sensorineural hearing loss (ISSNHL), the relationship between the administration duration of vitamin B12 (vit B12) with adenosine triphosphate (ATP) and their therapeutic effect is not fully understood. Objective:To investigate the therapeutic effect of long-term 16 (≥weeks) administrat...
journal_title:PeerJ
pub_type: 杂志文章
doi:10.7717/peerj.10406
更新日期:2020-12-16 00:00:00
abstract:BACKGROUND:Aspergillus niger, along with many other lignocellulolytic fungi, has been widely used as a commercial workhorse for cellulase production. A fungal cellulase system generally includes three major classes of enzymes i.e., β-glucosidases, endoglucanases and cellobiohydrolases. Cellobiohydrolases (CBH) are vita...
journal_title:PeerJ
pub_type: 杂志文章
doi:10.7717/peerj.3909
更新日期:2017-10-12 00:00:00
abstract::Because microorganisms are sensitive to temperature, ongoing global warming is predicted to influence microbial community structure and function. We used large-scale warming experiments established at two sites near the northern and southern boundaries of US eastern deciduous forests to explore how microbial communiti...
journal_title:PeerJ
pub_type: 杂志文章
doi:10.7717/peerj.358
更新日期:2014-04-24 00:00:00
abstract:Background:Sex ratio distorting agents (maternally inherited symbionts and meiotically-driving sex chromosomes) are common in insects. When these agents rise to high frequencies they create strong population sex ratio bias and selection then favours mutations that act to restore the rare sex. Despite this strong select...
journal_title:PeerJ
pub_type: 杂志文章
doi:10.7717/peerj.7677
更新日期:2019-10-01 00:00:00
abstract::The role of glial cells in pain modulation has recently gathered attention. The objective of this study was to determine healthy spinal microglia and astrocyte morphology and disposition in equine spinal cord dorsal horns using Iba-1 and GFAP/Cx-43 immunofluorescence labeling, respectively. Five adult horses without v...
journal_title:PeerJ
pub_type: 杂志文章
doi:10.7717/peerj.3965
更新日期:2017-10-27 00:00:00
abstract::A new Primulina species from Guangdong, China with an unusual inflorescence is described here. Primulina anisocymosa is vegetatively most similar to P. bobaiensis. It can be distinguished from all species within Primulina morphologically by its unique zigzag monochasial cyme and infructescence. To confirm the phylogen...
journal_title:PeerJ
pub_type: 杂志文章
doi:10.7717/peerj.6157
更新日期:2019-01-04 00:00:00
abstract:Background:G. boninense is a hemibiotrophic fungus that infects oil palms (Elaeis guineensis Jacq.) causing basal stem rot (BSR) disease and consequent massive economic losses to the oil palm industry. The pathogenicity of this white-rot fungus has been associated with cell wall degrading enzymes (CWDEs) released durin...
journal_title:PeerJ
pub_type: 杂志文章
doi:10.7717/peerj.8065
更新日期:2019-12-18 00:00:00