Abstract：
:Examination of the rectum by pathologists is instrumental in the management of patients affected by rectal carcinoma. That role includes evaluation of multiple gross and microscopic features that convey prognostic implications. The analysis is based on the authors' experience handling rectal specimens along with review of the pertinent literature in these areas: margins of excision, quality of the mesorectum, diligence and techniques to sample lymph nodes, tumor budding, grading of residual amount of carcinoma after preoperative therapy, vascular/perineural invasion, and staging the tumor. Pathologists must communicate the findings in a clear manner. Evaluation of margins and completeness of mesorectum are markers of the quality of surgical excision. The number of lymph nodes obtained and examined is dependent in great part on the diligence of the pathologist finding them in the mesenteric adipose tissue. There are grades for budding and response to prior chemoradiation therapy. The location of vascular invasion (extramural vs. intramural) may predict aggressive behavior. Pathologists proactively are to choose sections of tumor for molecular testing. Meticulous macro- and microscopic evaluation of specimens for rectal carcinoma by pathologist is needed to determine an accurate assessment of staging and other prognostic factors. The modern pathologists play a pivotal part in the care and management of patients suffering from rectal adenocarcinoma. That role goes from the initial histological diagnosis to the gross and microscopic examination of the excised specimens. Based on that examination pathologists issue statements that not only evaluate the quality of the surgical procedure, but also through the application of molecular tests they give light on prognostic factors and information for therapeutic purposes.
journal_name
Minerva Chirjournal_title
Minerva chirurgicaauthors
Berho M,Bejarano PAdoi
10.23736/S0026-4733.18.07739-8subject
Has Abstractpub_date
2018-12-01 00:00:00pages
534-547issue
6eissn
0026-4733issn
1827-1626pii
S0026-4733.18.07739-8journal_volume
73pub_type
杂志文章,评审abstract：AIMS AND BACKGROUND:Helicobacter pylori is known to be the pathogenic agent of atrophic gastritis and above all ulcer disease. It is also thought to play a role, together with other factors, in the development of stomach cancer and is currently the focus of numerous studies. In industrialised countries, infection is re...
journal_title：Minerva chirurgica
pub_type： 杂志文章
doi：
更新日期：1999-06-01 00:00:00
abstract：:This report describes 51 vascular patients with peripheral vascular disease treated intraoperatively by means of the autotransfusion apparatus with a minimum of 750 cc of reinfused blood. An early decrease of Hct, Hb, RBC, fibrinogen and Plt count was observed without any significant coagulation disorder. ...
journal_title：Minerva chirurgica
pub_type： 杂志文章
doi：
更新日期：1990-11-01 00:00:00
abstract：:Echotomography was used in the diagnosis of abdominal disease in children. The results obtained were compared with those given by conventional methods. The soundness of echotomography in the location and indication of the size and structure of lesions was demonstrated in a series of 20 cases. ...
journal_title：Minerva chirurgica
pub_type： 杂志文章
doi：
更新日期：1978-05-15 00:00:00
abstract：:On the basis of the anatomophysiological assumption that the abdominal oesophagus is kept in its seat by the meso-oesophagus and that the complex functional role of the gastro-oesophageal junction is conditioned essentially by the inferior oesophageal sphincter under the influence of intra-abdominal and endogastric pr...
journal_title：Minerva chirurgica
pub_type： 杂志文章
doi：
更新日期：1979-05-15 00:00:00
abstract：:The authors make a wide-ranging review of the literature, examine the epidemiological aspect of fail chest and underline the importance of its correct anatomopathological classification for a more qualified physiopathologist, diagnostic and therapeutic approach. They make a historical excursion on volet's treatment an...
journal_title：Minerva chirurgica
pub_type： 杂志文章,评审
doi：
更新日期：1994-03-01 00:00:00
abstract：:Personal experience of a fairly rare disease is reported and it is stressed that the decisive factor in opting for surgery is the diameter of the colon, particularly the cecum, on the basis of direct X-ray of the abdomen. It is considered that cecostomy is not only the simplest operation but is also the one that offer...
journal_title：Minerva chirurgica
pub_type： 杂志文章
doi：
更新日期：1989-04-15 00:00:00
abstract：BACKGROUND:Spontaneous rupture is a life-threatening complication of HCC, occurring in 4.8-26% of cases. Liver failure is the main cause of death. Debates still remain on the most appropriate treatment in such patients because of the high operative mortality of emergency surgery and the high risk of rebleeding and less...
journal_title：Minerva chirurgica
pub_type： 杂志文章
doi：
更新日期：2002-06-01 00:00:00
abstract：:The relationship between hyperthyroidism due to Graves' disease or toxic nodular goiters and carcinoma of the thyroid remains uncertain. The incidence of thyroid carcinoma varies considerably from as low as 0.3% to as high as 16.6% with a higher rate in toxic nodular goiters than in diffuse goiters and in endemic goit...
journal_title：Minerva chirurgica
pub_type： 临床试验,杂志文章
doi：
更新日期：1994-06-01 00:00:00
abstract：BACKGROUND:This study is to evaluate the efficacy and adverse reaction of a combination therapy of chemotherapy and laser thermal ablation (LTA) on liver metastases from colorectal cancer. METHODS:Eighty-five cases colorectal cancer liver metastases were assigned to the treatment group (43 cases) and to the control gr...
journal_title：Minerva chirurgica
pub_type： 杂志文章
doi：10.23736/S0026-4733.16.07204-7
更新日期：2017-02-01 00:00:00
abstract：BACKGROUND:Soft tissue defects are mostly managed surgically by free microvascular flaps. The progressive development of techniques and the availability and reliability of new different and free flaps encouraged this surgical approach. Thus, there is a constant need of free flap models to reproduce in laboratory. The e...
journal_title：Minerva chirurgica
pub_type： 杂志文章
doi：
更新日期：2002-08-01 00:00:00
abstract：:Deep venous thrombosis is a quite frequent pathology with a high degree of morbidity and death-rate. Two are the main problems of this disease: the risk of pulmonary embolism and outcome of a post-thrombotic syndrome, leading patients to infirmity. The patients max exposed to the risk of deep venous thrombosis are the...
journal_title：Minerva chirurgica
pub_type： 杂志文章
doi：
更新日期：1995-01-01 00:00:00
abstract：:The authors discuss the question of the reappearance of esophageal peristalsis following surgical or dilating treatment in patients with a diagnosis of cardiospasm. On the basis of their experience and an extensive review of the literature, the authors affirm that the reappearance of motor activity should not be attri...
journal_title：Minerva chirurgica
pub_type： 杂志文章,评审
doi：
更新日期：1993-10-31 00:00:00
abstract：BACKGROUND:Numerous hypotheses are called to explain the beneficial effect on glucose metabolism after bariatric surgery. Some authors advocate for the secretion and release of various substances with endocrine functions for the explanation on this event. One of the substances most marked as effector, with contrasting ...
journal_title：Minerva chirurgica
pub_type： 杂志文章
doi：10.23736/S0026-4733.18.07681-2
更新日期：2019-02-01 00:00:00
abstract：:The authors report a case of granular cell tumor of the breast arising in a 38-year old man. Preoperative diagnosis was of breast carcinoma. However, frozen sections showed the benign nature of the tumour. It is important to identify this lesion as, in spite of a clinical and mammographic similarity with carcinoma, it...
journal_title：Minerva chirurgica
pub_type： 杂志文章,评审
doi：
更新日期：1995-07-01 00:00:00
abstract：AIM:Systematic surveys with advanced non-invasive imaging techniques have revealed that hepatic cysts are quite common in the general population. Therefore, we retrospectively examined our case series and compared it with the literature. METHODS:Between January 1990 and December 2000, 228 patients with non-parasitic l...
journal_title：Minerva chirurgica
pub_type： 杂志文章
doi：
更新日期：2004-08-01 00:00:00
abstract：:The efficacy of defibrotide in the treatment of acute thrombophlebitis of the legs has been investigated in 140 patients, randomized into two groups. All patients received defibrotide either alone or as an addition to conventional therapies. Two different schemes of administration were selected and carried out in each...
journal_title：Minerva chirurgica
pub_type： 临床试验,杂志文章,随机对照试验
doi：
更新日期：1989-05-15 00:00:00
abstract：:Postoperative infections are the most frequent complications in surgery and are the commonest cause of the lengthening of hospital stay. The purpose of this study is to prospectively evaluate the incidence and predisposing factors of postoperative infections in 1396 surgical patients admitted to our Institute from 198...
journal_title：Minerva chirurgica
pub_type： 杂志文章
doi：
更新日期：1992-07-01 00:00:00
abstract：AIM:Postoperative air leaks and in particular persistent air leaks (>5 days) after pulmonary resection still represent a common complication and the first cause of hospital stay delay. Aim of this experimental trial was to investigate the efficacy of the use of bovine pericardium strips (in terms of reduction of postop...
journal_title：Minerva chirurgica
pub_type： 临床试验,杂志文章
doi：
更新日期：2012-02-01 00:00:00
abstract：:An uncommon complication of the sigmoid diverticulitis personally observed is described. A woman, 59 years old, presented a septic shock caused by perforated sigmoid diverticulum into the space of Retzius. The diagnosis was carried out by an X-ray of the abdomen that suspected the presence of air in the retroperitoneu...
journal_title：Minerva chirurgica
pub_type： 杂志文章
doi：
更新日期：2000-06-01 00:00:00
abstract：:In a previous study, we have shown that caerulein relieves biliary colic pain in gallstone patients. This study was initiated to determine gallbladder and sphincter of Oddi behaviour during biliary colic and their response to caerulein. In 10 gallstone patients gallbladder volume was measured by real-time ultrasonogra...
journal_title：Minerva chirurgica
pub_type： 杂志文章
doi：
更新日期：1996-12-01 00:00:00
abstract：:Insulinoma is the most common endocrine tumor of the pancreas. It arises from the beta-islet cells of Langerhans. Insulinomas synthesize and secrete insulin autonomously in the presence of low blood glucose levels, causing spontaneous hypoglycemia and characteristic clinical symptoms. The authors examined data the fro...
journal_title：Minerva chirurgica
pub_type： 杂志文章
doi：
更新日期：1997-03-01 00:00:00
abstract：:Thirty-four patients who underwent carotid-subclavian bypass (64.7%), aorto-carotid bypass (17.6%), endarterectomy of subclavian artery (5.8%) or endarterectomy of innominate artery for "subclavian" or "innominate steal" syndromes, had a follow-up studies 3-8 years since surgery. All patients demonstrated originally a...
journal_title：Minerva chirurgica
pub_type： 杂志文章
doi：
更新日期：1980-08-15 00:00:00
abstract：BACKGROUND:High resolution magnetic resonance cholangiopancreatography (MRCP) is a non invasive imaging modality for depicting the pancreatobiliary tree. It can demonstrate dilation, stenosis and intraductal filling defects of both the biliary and the pancreatic duct. The imaging quality of high resolution MRCP is exce...
journal_title：Minerva chirurgica
pub_type： 杂志文章
doi：
更新日期：2000-09-01 00:00:00
abstract：:Of 220 patients operated for gastric cancer, 74 with subtotal gastrectomy and 145 with total gastrectomy (60 with lymphadenectomy), the results and indications for total gastrectomy extended with lymphadenectomy are analysed. The importance of lymph node emptying in relation to the possibility of breakdown of the lymp...
journal_title：Minerva chirurgica
pub_type： 杂志文章
doi：
更新日期：1990-05-15 00:00:00
abstract：:The Authors examine retrospectively all the cases of obstruction of the small bowel operated at the surgical department of the Verbania Hospital in the last twenty years. The records of 341 cases, 1.4% of the total amount of the surgical operations carried out in the same space of time, were retrospectively reviewed. ...
journal_title：Minerva chirurgica
pub_type： 杂志文章
doi：
更新日期：1992-12-01 00:00:00
abstract：:A group of 20 patients underwent plastic surgery for inguinal hernia. In 10 cases the incision was sutured using a traditional technique, whereas in 10 cases the wound was joined using Fasterzip. The cosmetic appearance of the wound in the two groups was compared at 8, 30, 60 and 90 days after surgery. It was found th...
journal_title：Minerva chirurgica
pub_type： 临床试验,杂志文章
doi：
更新日期：1998-05-01 00:00:00
abstract：BACKGROUND:Meconium ileus (MI) is a form of neonatal intestinal obstruction due to an abnormal thickened meconium within the terminal ileum. The aim of this retrospective paper is to review our experience with neonates affected from MI treated at our institute over a twenty year period. METHODS:This report deals with ...
journal_title：Minerva chirurgica
pub_type： 杂志文章
doi：
更新日期：1999-12-01 00:00:00
abstract：:Authors describe a rare case of malignant schwannoma of the omentum. The diagnosis of schwannomas is often late because of the absence of early clinical signs. Clinical, diagnostic and histopathological considerations of these neoplasias are described in this work. ...
journal_title：Minerva chirurgica
pub_type： 杂志文章
doi：
更新日期：1993-01-01 00:00:00
abstract：:The authors present the diagnostic and therapeutic evolution of a case of duodenal duplication complicated by acute recurring pancreatitis in a eight-year-old boy. Abdominal pain and vomiting represented important clinical signs associated with a previous history of inexplicable episodes of acute pancreatitis. Abdomin...
journal_title：Minerva chirurgica
pub_type： 杂志文章
doi：
更新日期：2001-06-01 00:00:00
abstract：:The diaphragmatic hernia described by Morgagni in 1761 and by Larrey in 1829 is a rare diaphragmatic anomaly that may be considered nearly always congenital. It is called in so many ways, but the authors think that "anterior diaphragmatic hernia of Morgagni-Larrey" is the most correct name. Usually asymptomatic in the...
journal_title：Minerva chirurgica
pub_type： 杂志文章
doi：
更新日期：1994-11-01 00:00:00
