Abstract：
BACKGROUND:This study is to evaluate the efficacy and adverse reaction of a combination therapy of chemotherapy and laser thermal ablation (LTA) on liver metastases from colorectal cancer. METHODS:Eighty-five cases colorectal cancer liver metastases were assigned to the treatment group (43 cases) and to the control group (42 cases). The treatment group patients received LTA combined with FOLFIRI regimen chemotherapy, and the control group patients only received FOLFIRI regimen chemotherapy. The curative effects, the survival rate and adverse reaction of the two groups were observed and evaluated. RESULTS:Response rate was 53.4% in the treatment group and 38.1% in the control group (P>0.05); disease control rate in the treatment group was 79.1%, higher than 64.3% in control group with significant difference (P<0.01); median progression free survival was 11.8 months in treatment group and 6.8 months in control group (P<0.01); The median overall survival time was 19.1 months in treatment group and 14.9 months in control group (P<0.05). Among the 113 lesions receiving LTA, 104 lesions (92%) were completely destroyed. The main complications of LTA were fever and local pain. The adverse effects between both groups showed no difference. CONCLUSIONS:LTA in combination with chemotherapy of colorectal carcinoma liver metastases is effective and well-tolerated.
journal_name
Minerva Chirjournal_title
Minerva chirurgicaauthors
Lichun D,Dazhong Z,Wei Sheng S,Xiongwei L,Huaming S,Lei X,Jie Z,Xiangming Cdoi
10.23736/S0026-4733.16.07204-7subject
Has Abstractpub_date
2017-02-01 00:00:00pages
18-23issue
1eissn
0026-4733issn
1827-1626pii
R06Y9999N00A16102702journal_volume
72pub_type
杂志文章abstract：:Operations and follow-up examinations were conducted on 106 patients with ulcerative colitis, 33 with colitis Crohn, and 163 with diverticulitis, at the University Clinics of Cologne and Munich. Overall mortality rates were 24.5% (n = 26), 6.1% (n = 2) and 16% (n = 26), respectively. In the surgical treatment of ulcer...
journal_title：Minerva chirurgica
pub_type： 杂志文章
doi：
更新日期：1978-06-15 00:00:00
abstract：:Although the common bile duct is now accessed using a coelioscopic approach by an increasing number of surgical equipes, the problems related to the diagnostic iter of lithiasis of the common bile duct and the need to obtain a correct preoperative diagnosis, in order to select the most appropriate form of therapy, are...
journal_title：Minerva chirurgica
pub_type： 杂志文章,评审
doi：
更新日期：1995-03-01 00:00:00
abstract：:The efficacy of two methods of orthograde lavage preparation in elective colorectal surgery was tested in 133 consecutive patients: the results obtained with whole gut irrigation (50 patients, group A) were compared with the results of oral lavage solution (83 patients, group B). All patients received a parenteral ass...
journal_title：Minerva chirurgica
pub_type： 杂志文章
doi：
更新日期：1992-08-01 00:00:00
abstract：BACKGROUND AND AIM:Over the past decade the use of surgical staplers has resulted in a substantial change in both elective and emergency surgery for gastrointestinal pathologies. A large number of studies have now affirmed the safety, reliability, simplicity, rapidity and usefulness of these instruments. They offer man...
journal_title：Minerva chirurgica
pub_type： 杂志文章
doi：
更新日期：1999-05-01 00:00:00
abstract：:Small cell carcinoma of the esophagus is a rare tumor. It was described for the first time in 1952 by McKeown and 200 cases have been reported till now. Because of its similarity with small cell carcinoma of the lung, the treatment of this tumor is controversial. In our Institute we treated three patients with small c...
journal_title：Minerva chirurgica
pub_type： 杂志文章
doi：
更新日期：2003-08-01 00:00:00
abstract：:The ultrasonic scalpel has been used for some time in surgery in tissue with a predominantly cellular component since it can be used selectively on the parenchymatous component while respecting the vasculo-stromal component. On the basis of their earlier experience and using a versatile ultrasonic device currently uti...
journal_title：Minerva chirurgica
pub_type： 杂志文章
doi：
更新日期：1994-01-01 00:00:00
abstract：:Reference is made to a personal case in an examination of the more controversial aspects of segmentary necrosis of the main bile pathway. Attention is drawn to the leading features of the pathogenetic evolution of this lesion. Bearing in mind the almost insurmountable difficulty of formulating a preoperative diagnosis...
journal_title：Minerva chirurgica
pub_type： 杂志文章
doi：
更新日期：1979-05-31 00:00:00
abstract：:The Mirizzi syndrome is an unusual benign obstructive jaundice due to extrinsic mechanical compression of the common hepatic duct by gallstone impacted within the neck or cystic duct of the gallbladder. This syndrome is described either as an acute form due only to extrinsic compression of the common bile duct (type I...
journal_title：Minerva chirurgica
pub_type： 杂志文章
doi：
更新日期：1995-06-01 00:00:00
abstract：:The authors report a case in which a PTFE prosthesis, used to treat a voluminous hiatal sliding hernia, dislocated inside the cardial lumen. Within two months the prosthesis had become decubitant and penetrated the cardial lumen, causing dysphagia, inappetence and weight loss. The use of radiological and tomographic i...
journal_title：Minerva chirurgica
pub_type： 杂志文章
doi：
更新日期：2000-05-01 00:00:00
abstract：:Infected vascular grafts are associated with very high rates of limb loss and mortality. "Classic" treatment has invariably included graft excision. Recent reports have suggested that a more conservative approach may be indicated in selected cases, leaving the graft in place and using an aggressive local treatment ass...
journal_title：Minerva chirurgica
pub_type： 杂志文章,评审
doi：
更新日期：1994-05-01 00:00:00
abstract：:A series of cases of acute pancreatitis treated between 1-XI-1972 and 1-XI-1975 is presented. A division is made between cases acute ab initio and postoperative pancreatitis, the latter further subdivided into pancreatic necroses, oedemas, and slight affections. The question of diagnosis is examined and elements indic...
journal_title：Minerva chirurgica
pub_type： 杂志文章
doi：
更新日期：1976-10-31 00:00:00
abstract：:Videolaparoscopic cholecystectomy is considered the treatment of choice for simple cholelithiasis. Now many surgeons consider the laparscopic procedure usable also in the complicated biliary lithiasis like acute cholecystitis and choledocholithiasis. The authors report their recent experience of the laparoscopic treat...
journal_title：Minerva chirurgica
pub_type： 杂志文章
doi：
更新日期：1998-03-01 00:00:00
abstract：:A series of 234 patients who underwent Billroth I gastric resection for gastric and duodenal ulcerous lesions is reported. Special attention is paid to the immediate postoperative complications whose incidence was 5.5%. Particularly serious is the dehiscence of gastroduodenal anastomosis which requires emergency recon...
journal_title：Minerva chirurgica
pub_type： 杂志文章
doi：
更新日期：1979-02-15 00:00:00
abstract：:Of 220 patients operated for gastric cancer, 74 with subtotal gastrectomy and 145 with total gastrectomy (60 with lymphadenectomy), the results and indications for total gastrectomy extended with lymphadenectomy are analysed. The importance of lymph node emptying in relation to the possibility of breakdown of the lymp...
journal_title：Minerva chirurgica
pub_type： 杂志文章
doi：
更新日期：1990-05-15 00:00:00
abstract：:Reference is made to personal experience (421 lumbar sympathectomies in 1640 vascular operations carried out over the last ten years) and the results of an enquiry addressed to more than 200 Italian surgeons are cited for the proposition that the indications for this operation are still the subject of disagreement, wh...
journal_title：Minerva chirurgica
pub_type： 杂志文章,评审
doi：
更新日期：1981-09-30 00:00:00
abstract：:A case of intestinal occlusion is reported caused by volvulus of Meckel's diverticulum. The etiological and clinical aspects are discussed together with their implications in terms of suitable surgical therapy. ...
journal_title：Minerva chirurgica
pub_type： 杂志文章
doi：
更新日期：1990-06-30 00:00:00
abstract：:Following a discussion of the various methods of colorectal anastomosis in cancer surgery, the Authors describe a technical variant using a mechanical stapler in a high rectal location. The rapidity of anastomosis as well as the decreased risk of dehiscence, fistula and stenosis are underlined. ...
journal_title：Minerva chirurgica
pub_type： 杂志文章
doi：
更新日期：1992-09-30 00:00:00
abstract：BACKGROUND:External hemorrhoidal thrombosis is a common disease with an acute anal pain as the major symptom. It is astonishing the lack of studies which investigates the most effective treatment and there are not guidelines. Furthermore, nobody has ever evaluated this peculiar condition in an elderly population. METH...
journal_title：Minerva chirurgica
pub_type： 杂志文章
doi：10.23736/S0026-4733.18.07724-6
更新日期：2020-04-01 00:00:00
abstract：:Biliodigestive fistulas are the most frequent internal biliary fistulas and occur when a calculus or neoplasia perforates the wall of the biliary tract of intestine at any point. Symptoms vary given that completely asymptomatic cases have been reported in which the findings of a biliodigestive fistula was completely c...
journal_title：Minerva chirurgica
pub_type： 杂志文章,评审
doi：
更新日期：1997-04-01 00:00:00
abstract：:Successful closure of a iatrogenic tracheoesophageal fistula by means of bronchoscopic application of fibrin glue in a 77-year old patient is reported. The fistula was completely obliterated after a single application of the glue, with resolution of the clinical and radiological signs. The procedure may be suggested a...
journal_title：Minerva chirurgica
pub_type： 杂志文章
doi：
更新日期：1993-10-15 00:00:00
abstract：:A case of pseudocyst of an asymptomatic right suprarenal gland found by chance is reported. Some aetiopathogenetic, anatomopathological and clinico-radiological aspects of the condition are discussed and, after reviewing the possible complications that may arise out of a suprarenal cyst, the value of surgery is stress...
journal_title：Minerva chirurgica
pub_type： 杂志文章
doi：
更新日期：1980-02-29 00:00:00
abstract：:An increased risk of colorectal cancer has been reported in first-degree relatives of affected patients, and following cholecystectomy or partial gastrectomy for benign peptic ulcer disease. The aim of this study was to examine the incidence of these potential risk factors in 197 patients (127 males, 70 females, mean ...
journal_title：Minerva chirurgica
pub_type： 杂志文章
doi：
更新日期：1996-12-01 00:00:00
abstract：INTRODUCTION:We provide a comprehensive description of the physio-pathological theories behind oligometastatic prostate cancer (PCa) and analyze modern imaging techniques, presenting a systematic review of the available evidences regarding salvage lymph node dissection (sLND). EVIDENCE ACQUISITION:A systematic review ...
journal_title：Minerva chirurgica
pub_type： 杂志文章
doi：10.23736/S0026-4733.18.07796-9
更新日期：2019-02-01 00:00:00
abstract：:Advanced hepatocellular carcinoma remains an entity that is hard to approach therapeutically and has shown disappointing results in terms of survival. For many years, the only accepted option for this setting was the use of a multikinase inhibitor, sorafenib. Nevertheless, through the years, a deeper knowledge has ari...
journal_title：Minerva chirurgica
pub_type： 杂志文章,评审
doi：
更新日期：2015-04-01 00:00:00
abstract：AIM:This study was designed to investigate the risk factors of pelvic lymph node metastasis in early stage cervical cancer in order to establish a prediction model for this metastasis and to explore the feasibility of conservative surgery. METHODS:The records of 207 stage IB-IIA cervical cancer patients were retrospec...
journal_title：Minerva chirurgica
pub_type： 杂志文章
doi：
更新日期：2011-12-01 00:00:00
abstract：:Two cases of congenital diaphragmatic hernia affecting the central tendon are described. The anatomic, etiologic, pathogenic and clinic characteristics of this uncommon disease are then discussed. Finally some considerations about indications on how to operate on these congenital hernias and different repairing surgic...
journal_title：Minerva chirurgica
pub_type： 杂志文章
doi：
更新日期：1981-06-15 00:00:00
abstract：:The authors report a case of associated injuries (thoracoabdominal trauma with multiple rib and sternum fractures, perforation of the small intestine, abdominal cutaneous ecchymosis) caused by a seat belt, and describe the possible seat-belt mechanisms of lesion in road accidents. Some clinical aspects are discussed; ...
journal_title：Minerva chirurgica
pub_type： 杂志文章
doi：
更新日期：1993-05-15 00:00:00
abstract：:The pheochromocytoma is a catecholamine-secreting tumor, localized in the adrenal gland in 90% of the cases and in extra-adrenal site in the remaining 10%. It can be single or associated with other endocrine neoplasms. On the basis of the case presented, the several clinical manifestations, the treatment of the diseas...
journal_title：Minerva chirurgica
pub_type： 杂志文章,评审
doi：
更新日期：1999-04-01 00:00:00
abstract：:A case of giant hydatid cyst of the left lung submitted to conservative surgery is reported. The postoperative period was complicated by the appearance of a bronchopleural fistula and a residual cavity. The complication was treated with targeted double lumen drainage which enabled pleuroclysis with saline solution and...
journal_title：Minerva chirurgica
pub_type： 杂志文章
doi：
更新日期：2000-07-01 00:00:00
abstract：:Phlebology has made considerable efforts to free itself from empiricism in recent years. Careful scientific methods have enabled previously unhoped-for results to be obtained in very widespread and debilitating diseases. New and in some cases revolutionary concepts are described, whose application presupposes the exis...
journal_title：Minerva chirurgica
pub_type： 杂志文章
doi：
更新日期：1975-10-31 00:00:00
