Abstract：
BACKGROUND/OBJECTIVES:Surgical extirpation for hepatocellular carcinoma (HCC) with background fibrosis remains a challenge. This study evaluated impact of fibrosis score on long term outcomes of patients undergoing surgical resection for HCC. METHODS:Using the Surveillance, Epidemiology and End Results (SEER) database (2004-2013), complete data on 1433 patients undergoing surgical resection for non-metastatic HCC were identified. Overall survival (OS) was estimated using the Kaplan-Meier method. Cox proportional hazards model were used to produce adjusted hazard ratios (HR). RESULTS:In this study, 54% (650/1433) patients had F5-6 fibrosis at the time for surgical resection of HCC. In adjusted models, F5/6 fibrosis significantly reduces overall survival (HR: 1.62, 95% CI: 1.34-1.94; p < 0.001). Median survival was significantly longer for patients with F0-4 fibrosis for T1a, T1b and T2 tumours as compared to F5-6 fibrosis, not for T3 and T4 tumours, even when stratified by extent of hepatectomy. There were no significant differences in 90-day post-operative mortality between fibrosis groups when stratified by T-classifications. CONCLUSION:Liver resection in patients with advanced fibrosis has significantly lower survival as compared to patients with F0-4 fibrosis in early stage (T1 and T2), not advanced tumours (T3 and T4). Improvement in patient selection and perioperative care for liver resection may offer consistent and clinically meaningful long-term survival in HCC.
journal_name
Asian J Surgjournal_title
Asian journal of surgeryauthors
Kamarajah SKdoi
10.1016/j.asjsur.2018.01.001subject
Has Abstractpub_date
2018-11-01 00:00:00pages
551-561issue
6eissn
1015-9584issn
0219-3108pii
S1015-9584(17)30487-6journal_volume
41pub_type
杂志文章abstract：:Massive defects of the upper aerodigestive tract present a reconstructive challenge. We report a case in which a large defect of the naso-oropharyngeal and oesophagus was reconstructed with a combination of a gastric pull-up and a pectoralis major muscle flap. Postoperative function was good and survival was in excess...
journal_title：Asian journal of surgery
pub_type： 杂志文章
doi：10.1016/S1015-9584(09)60203-7
更新日期：2002-10-01 00:00:00
abstract：:Magnetic resonance cholangiography (MRC) is a non-invasive imaging modality that has become widely available. In the short time since its introduction, MRC has been shown to possess excellent accuracy for the diagnosis of various biliary pathologies, including choledocholithiasis. Investigations of the clinical applic...
journal_title：Asian journal of surgery
pub_type： 杂志文章,评审
doi：10.1016/S1015-9584(09)60321-3
更新日期：2004-04-01 00:00:00
abstract：INTRODUCTION:The traditionally taught technique for conventional open thyroidectomy is via a midline splitting of the strap muscles following a skin crease neck incision - midline approach (MA). The lateral "backdoor" approach (LA) uses the same central neck incision but approaches the thyroid gland between the anterio...
journal_title：Asian journal of surgery
pub_type： 杂志文章
doi：10.1016/j.asjsur.2017.05.003
更新日期：2018-07-01 00:00:00
abstract：BACKGROUND:Hemorrhoidectomy is commonly associated with postoperative pain. Calcium channel blockers are known to cause relaxation of gastrointestinal smooth muscle and oral diltiazem has also been shown to reduce the resting anal pressure. OBJECTIVE:We attempted to analyze efficacy and side effects of topical diltiaz...
journal_title：Asian journal of surgery
pub_type： 杂志文章,meta分析
doi：10.1016/j.asjsur.2017.06.002
更新日期：2018-09-01 00:00:00
abstract：:Lymphangiomas are congenital malformations of the lymphatic system, and 90% have manifested by the end of the second year of life. While 75% of these are located in the cervical region, only 2% to 3% are associated with an intrathoracic extension. An isolated mediastinal lymphangioma without a cervical component is an...
journal_title：Asian journal of surgery
pub_type： 杂志文章
doi：10.1016/S1015-9584(09)60042-7
更新日期：2004-07-01 00:00:00
abstract：OBJECTIVE:This study investigated the effectiveness of unilateral nephrectomy in the treatment of renal hypertension in adults with an atrophic kidney, and set out to establish whether this is an appropriate mode of treatment for renal hypertension not otherwise controlled by antihypertensive drugs or other surgical pr...
journal_title：Asian journal of surgery
pub_type： 杂志文章
doi：10.1016/S1015-9584(08)60083-4
更新日期：2008-10-01 00:00:00
abstract：BACKGROUND:We report the short-term clinical outcomes of a delta-shaped (DS) anastomosis in laparoscopic distal gastrectomy (LDG), comparing Endo GIA™ Reinforced Reload (Reinforced GIA) with Endo GIA™ (GIA) staplers. METHODS:This was a retrospective analysis of 40 patients who underwent totally LDG with DS anastomosis...
journal_title：Asian journal of surgery
pub_type： 杂志文章
doi：10.1016/j.asjsur.2017.04.002
更新日期：2018-09-01 00:00:00
abstract：BACKGROUND:We report initial surgical results and learning process of single-port video-assisted thoracoscopic surgery (VATS) subsegmentectomy in comparison with segmentectomy in our institution as the presentative of minimal invasiveness and precise resection for early stage lung cancer. METHODS:All patients undergoi...
journal_title：Asian journal of surgery
pub_type： 杂志文章
doi：10.1016/j.asjsur.2019.09.009
更新日期：2020-05-01 00:00:00
abstract：BACKGROUND:Routine therapy of metabolic bone disorder (MBD) after gastrectomy for gastric cancer has not been established yet. We have reported that administering an active vitamin D3 agent to patients who had undergone gastrectomy for gastric cancer improved MBD. Recently, the usefulness of alendronate, an osteoclast ...
journal_title：Asian journal of surgery
pub_type： 杂志文章
doi：10.1016/j.asjsur.2016.07.003
更新日期：2017-11-01 00:00:00
abstract：BACKGROUND:5-Aminolevulinic Acid (5-ALA) induced fluorescence is useful in guiding glioma resection. The extent of 5-ALA accumulation is beyond gadolinium contrast enhancement.1,2 Supratotal resection may be achieved, potentially granting patients with better survival. We present our experience on 5-ALA guided glioma r...
journal_title：Asian journal of surgery
pub_type： 杂志文章
doi：10.1016/j.asjsur.2017.06.004
更新日期：2018-09-01 00:00:00
abstract：BACKGROUND/OBJECTIVES:To investigate the oncological and functional outcomes after partial nephrectomy for clinical stage T1 (cT1) renal cell carcinoma (RCC), and assess the association between excisional volume loss (EVL) and postoperative renal function. METHODS:We retrospectively reviewed 150 patients with cT1 RCC ...
journal_title：Asian journal of surgery
pub_type： 杂志文章
doi：10.1016/j.asjsur.2019.05.015
更新日期：2020-01-01 00:00:00
abstract：BACKGROUND:To elucidate the clinicopathological features of multiply recurrent retroperitoneal liposarcoma referred to a tertiary center. METHODS:We retrospectively analyzed the clinical data of 40 patients with pathologically proven primary retroperitoneal liposarcoma treated between January 2015 and June 2019. RESU...
journal_title：Asian journal of surgery
pub_type： 杂志文章
doi：10.1016/j.asjsur.2020.10.015
更新日期：2021-01-01 00:00:00
abstract：OBJECTIVE:Vesicovaginal fistula is mostly iatrogenic in origin and causes devastating medical, social, psychogenic and hygienic consequences. The aetiology has changed since the nineteenth century, becoming more associated with hysterectomy rather than other obstetric procedures, which were common in the past. We studi...
journal_title：Asian journal of surgery
pub_type： 杂志文章
doi：10.1016/S1015-9584(08)60037-8
更新日期：2007-10-01 00:00:00
abstract：:Intravesical Bacillus Calmette-Guérin (BCG) has been a proven and effective immunotherapy treatment for superficial transitional cell carcinoma (TCC) of the bladder, especially for high-grade tumors and carcinoma in situ. Nevertheless, significant side effects are associated with BCG instillations, including fever, my...
journal_title：Asian journal of surgery
pub_type： 杂志文章
doi：10.1016/j.asjsur.2014.01.016
更新日期：2017-04-01 00:00:00
abstract：:We report two cases of prenatally diagnosed cystic neuroblastoma (PDCN). In the first case, prenatal ultrasonography (US) at 33 weeks' gestation showed a 30 x 20 mm cyst at the upper pole of the right kidney. The size and content of the mass demonstrated no change during pregnancy. Postnatal US showed no change in the...
journal_title：Asian journal of surgery
pub_type： 杂志文章
doi：10.1016/s1015-9584(09)60309-2
更新日期：2003-10-01 00:00:00
abstract：:Chylous ascites specifically after anterior resection for rectal cancer has not been documented in the literature thus far. All previously reported postoperative chylous ascites developed in other types of malignancies and were diagnosed within a few days of surgery. However, the patient we report had symptoms 2 years...
journal_title：Asian journal of surgery
pub_type： 杂志文章
doi：10.1016/S1015-9584(09)60295-5
更新日期：2006-01-01 00:00:00
abstract：:We report a patient with familial hypocalciuric hypercalcemia (FHH) associated with primary hyperparathyroidism (PHPT) and incidental papillary thyroid carcinoma. The patient showed hypercalcemia, high parathyroid hormone (PTH) levels and low urinary calcium excretion. A computed tomography (CT) scan revealed an enlar...
journal_title：Asian journal of surgery
pub_type： 杂志文章
doi：10.1016/S1015-9584(09)60022-1
更新日期：2009-04-01 00:00:00
abstract：BACKGROUND:Papillary thyroid carcinoma (PTC) is the main type of the well-differentiated thyroid carcinomas. Multifocality is regarded as a poor prognostic factor for PTC. METHODS:Documents of 777 patients who underwent thyroidectomy were reviewed retrospectively. A total of 305 PTC patients were included. Patients wi...
journal_title：Asian journal of surgery
pub_type： 杂志文章
doi：10.1016/j.asjsur.2018.05.004
更新日期：2019-01-01 00:00:00
abstract：:Sarcopenia refers to the progressive and generalised loss of skeletal muscle mass and strength with a risk of adverse outcomes such as physical disability, poor quality of life and mortality. The present review explored the impact, diagnosis, prevention and management of sarcopenia in surgical and trauma patients. Rec...
journal_title：Asian journal of surgery
pub_type： 杂志文章,评审
doi：10.1016/j.asjsur.2019.10.010
更新日期：2020-06-01 00:00:00
abstract：BACKGROUND/OBJECTIVE:Patients on hemodialysis (HD) who undergo abdominal surgery for gastrointestinal disease are at increased risk of postoperative complications. In this study, we retrospectively investigated the predictors of postoperative complications among such patients. METHODS:The study group comprised 36 HD p...
journal_title：Asian journal of surgery
pub_type： 杂志文章
doi：10.1016/j.asjsur.2015.03.013
更新日期：2016-10-01 00:00:00
abstract：:Surgical smoke is the gaseous by-product formed during surgical procedures. Most surgeons, operating theatre staff and administrators are unaware of its potential health risks. Surgical smoke is produced by various surgical instruments including those used in electrocautery, lasers, ultrasonic scalpels, high speed dri...
journal_title：Asian journal of surgery
pub_type： 杂志文章
doi：10.1016/S1015-9584(09)60403-6
更新日期：2009-10-01 00:00:00
abstract：BACKGROUND:The ipsilateral nipple has been used as a directional guide for needle advance during internal jugular vein (IJV) catheterization. We attempted to validate the utility of the ipsilateral nipple during IJV catheterization. METHODS:One hundred and two patients scheduled for elective surgery were enrolled. In ...
journal_title：Asian journal of surgery
pub_type： 杂志文章
doi：10.1016/j.asjsur.2018.04.003
更新日期：2019-01-01 00:00:00
abstract：BACKGROUND:An effective regimen to treat patients suffering from acute necrotizing fasciitis requires surgical removal of devitalized tissues, systemic administration of broad antimicrobials and ameliorating underlying systemic disease processes. The task of managing wounds consequential to surgical debridement, on the...
journal_title：Asian journal of surgery
pub_type： 杂志文章,随机对照试验
doi：10.1016/S1015-9584(09)60072-5
更新日期：2006-07-01 00:00:00
abstract：BACKGROUND/OBJECTIVE:One thousand liver transplantations have been performed at the only liver transplant center in Hong Kong over a period of 22 years, which covered the formative period of living donor liver transplantation. These 1000 transplantations, which marked the journey of liver transplantation from developme...
journal_title：Asian journal of surgery
pub_type： 杂志文章
doi：10.1016/j.asjsur.2015.03.018
更新日期：2016-10-01 00:00:00
abstract：OBJECTIVE:To report our experience in treating endophytic renal tumor by robot-assisted partial nephrectomy (RPN) with a standard laparoscopic ultrasound probe and our original approach for separating renal mass. METHODS:All patients with endophytic renal tumor who underwent RPN in our department from January 2015 to ...
journal_title：Asian journal of surgery
pub_type： 杂志文章
doi：10.1016/j.asjsur.2019.07.005
更新日期：2020-02-01 00:00:00
abstract：BACKGROUND:Little is known about the preoperative predictive factors that could identify subsets of favorable patients who can be possibly cured with robot-assisted radical prostatectomy (RARP) alone in locally advanced prostate cancer (LAPCa). Our study was designed to identify clinical predictors of pathologic organ-...
journal_title：Asian journal of surgery
pub_type： 杂志文章
doi：10.1016/j.asjsur.2017.10.005
更新日期：2019-01-01 00:00:00
abstract：OBJECTIVE:This study investigated the effects of posture and also intermittent foot and calf compression on peak systolic flow of the popliteal artery in a normal population. METHODS:This was a prospective study carried out in normal subjects at the Vascular Laboratory, Department of Surgery, Hospital Kuala Lumpur, fr...
journal_title：Asian journal of surgery
pub_type： 杂志文章
doi：10.1016/s1015-9584(08)60072-x
更新日期：2008-07-01 00:00:00
abstract：OBJECTIVE:We tracked various proficiency indicators for the learning curve as a single Taiwanese surgeon became familiar with robotic-assisted laparoscopic radical prostatectomy surgeries by performing 60 initial procedures. METHODS:Between December 2005 and December 2007, 60 consecutive patients were classified into ...
journal_title：Asian journal of surgery
pub_type： 杂志文章
doi：10.1016/S1015-9584(11)60023-7
更新日期：2011-04-01 00:00:00
abstract：OBJECTIVE:To determine the 5-year survival rate and prognostic factors for survival in patients with colorectal cancer treated at the Surgical Unit, Hospital Universiti Sains Malaysia (HUSM), Kelantan, Malaysia. METHODS:We retrospectively reviewed the records of 115 patients treated in HUSM from 1996 to 2005. Data of ...
journal_title：Asian journal of surgery
pub_type： 杂志文章
doi：10.1016/S1015-9584(10)60022-X
更新日期：2010-07-01 00:00:00
abstract：:This meta-analysis aimed to explore the effect of infrahepatic vena cava (IVC) clamping on bleeding during hepatic resection. PubMed and Embase databases were searched systematically to identify randomized controlled trials (RCTs) comparing infrahepatic IVC clamping to IVC nonclamping during hepatic resection. A rando...
journal_title：Asian journal of surgery
pub_type： 杂志文章,meta分析,评审
doi：10.1016/j.asjsur.2017.11.003
更新日期：2018-11-01 00:00:00
