The effect of no drainage in patients who underwent thyroidectomy with neck dissection: A systematic review and meta-analysis.

Abstract:

BACKGROUND:To evaluate the effect of no drainage in patients who underwent thyroidectomy and neck lymph node dissection. METHODS:We followed the methodological standard expected by Cochrane. We searched the following databases by March 23, 2017: PubMed, The Cochrane Library, EMBASE via Ovid SP, and Medline via Ovid SP. Two reviewers screened the studies and extracted the data. Randomized controlled trials (RCTs) or nonrandomized interventional studies assessing the effect of no drainage following thyroidectomy with lymph node dissection were included. RESULTS:Three studies with 387 participants were included. There was no statistical difference between groups for the overall perioperative complications (2 RCTs, n = 234, RR 1.56, 95% CI 0.53-4.64), or specific complications such as seroma (2 RCTs, n = 234, RR 1.81, 95% CI 0.46-7.07), hematoma (2 RCTs, n = 234, RR 0.72, 95% CI 0.11-4.83) or hemorrhage (1 RCT, n = 69, RR 0.29, 95% CI 0.01-6.87). One case required reoperation due to hemorrhage in the drainage group was reported in 1 study (n = 32). No mortality was reported. Two studies (n = 234) stated a longer hospital stay in the drainage group than that in the group without drainage. There was moderate or serious bias for the risk of bias of included studies. CONCLUSION:The effect of no-drainage in patients with thyroid cancer who received thyroidectomy with neck dissections remains uncertain, since there are very few studies that addressed the question. Drainage may lead to longer hospital stay than nondrainage. More randomized or nonrandmized studies are required to address this issue.

journal_name

Medicine (Baltimore)

journal_title

Medicine

authors

Li L,Chen H,Tao H,Liu W,Li W,Leng Z,Zhao E,Huang T

doi

10.1097/MD.0000000000009052

subject

Has Abstract

pub_date

2017-12-01 00:00:00

pages

e9052

issue

50

eissn

0025-7974

issn

1536-5964

pii

00005792-201712150-00050

journal_volume

96

pub_type

杂志文章,meta分析,评审

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