How relevant are vascular endothelial growth factor and intercellular adhesion molecule in the systemic capillary leak syndrome of psoriasis?

Abstract:

:Psoriasis is a chronic disease, characterized by erythematous scaly lesions, presented in eight different forms: plaques, guttate, pustular, erythrodermic, inverse, nail and scalp psoriasis, and psoriatic arthritis. Its development depends on genetic factors, external stimulus and immune response alteration.1 Proinflammatory cytokines such as TNF-alpha, IL-12 and 23 may also be involved. In the worst cases, systemic complications linked to endothelial alterations may occur. A literature review was conducted for a better understanding of what roles VEGF (vascular endothelial growth factor) and ICAM-1 (intercellular adhesion molecule) have, among other cytokines, in systemic capillary leak syndrome, involved in erythrodermic and pustular psoriasis, the most unstable forms of the disease.

journal_name

An Bras Dermatol

authors

Bressan AL,Pereira D,Medeiros PM,Carneiro S,Azulay-Abulafia L

doi

10.1590/abd1806-4841.20175994

subject

Has Abstract

pub_date

2017-11-01 00:00:00

pages

826-829

issue

6

eissn

0365-0596

issn

1806-4841

pii

S0365-05962017000600826

journal_volume

92

pub_type

杂志文章,评审
  • Histogenetic categorization of atypical melanocytic tumor of uncertain biological malignant potential.

    abstract::Several reports have demonstrated difficulties and lack of agreement in the histopathological diagnosis of particular melanocytic lesions, with problems in their management. A histogenetic approach to the study of these lesions originated the following classification: 1. superficial atypical proliferation significance...

    journal_title:Anais brasileiros de dermatologia

    pub_type: 杂志文章

    doi:10.1590/abd1806-4841.20187608

    authors: Pusiol T

    更新日期:2018-07-01 00:00:00

  • Periungual basal cell carcinoma.

    abstract::Periungual basal cell carcinoma is rare and needs to be differentiated from other common diseases that affect this region. Several factors are associated with the development of this tumor, and sun damage seems to play an important role in its pathogenesis. Dermoscopy of clinically indolent lesions on the nail unit ca...

    journal_title:Anais brasileiros de dermatologia

    pub_type:

    doi:10.1590/abd1806-4841.20186515

    authors: Tavares LL,Costa JCMD,Delcourt NC,Rodrigues NCDS

    更新日期:2018-01-01 00:00:00

  • Immunological mapping in hereditary epidermolysis bullosa.

    abstract::Immunological mapping, an immunofluorescence technique, is currently the method most used to diagnose and differentiate the principal types of hereditary epidermolysis bullosa, since this technique is capable of determining the level of cleavage of this mechanobullous disease. ...

    journal_title:Anais brasileiros de dermatologia

    pub_type: 杂志文章,评审

    doi:10.1590/s0365-05962010000600012

    authors: Oliveira ZN,Périgo AM,Fukumori LM,Aoki V

    更新日期:2010-11-01 00:00:00

  • Cutaneous mosaicisms: concepts, patterns and classifications.

    abstract::A mosaic is an organism composed of two or more genetically distinct cell populations derived from a genetically homogeneous zygote. Cutaneous mosaicisms are the clinical expressions of these disorders. The main event which allows the existence of mosaicism is a genetic mutation, either structural or functional. Cutan...

    journal_title:Anais brasileiros de dermatologia

    pub_type: 杂志文章,评审

    doi:10.1590/abd1806-4841.20132015

    authors: Kouzak SS,Mendes MS,Costa IM

    更新日期:2013-07-01 00:00:00

  • Erythroplasia of Queyrat treated with topical 5-fluorouracil.

    abstract::We report a 33-year-old male patient diagnosed with erythroplasia of Queyrat. The patient had an erythematous and eroded lesion affecting more than 50% of the glans associated with bleeding and local pain. Despite previous indication of penectomy, he was successfully treated with topical 5-fluorouracil. ...

    journal_title:Anais brasileiros de dermatologia

    pub_type:

    doi:10.1590/abd1806-4841.20164595

    authors: Antônio JR,Antônio CR,Trídico LA,Alves FT,Rollemberg I

    更新日期:2016-09-01 00:00:00

  • Skin cancer incidence in rural workers at a reference hospital in western Paraná.

    abstract:BACKGROUND:Skin cancer is common in Brazil and is related to sun exposure, among other risk factors. There are no data on the incidence of malignant skin neoplasm in rural workers in western Paraná. OBJECTIVE:To analyze the incidence and profile of rural workers who were diagnosed with skin cancer at a reference servi...

    journal_title:Anais brasileiros de dermatologia

    pub_type: 杂志文章

    doi:10.1590/abd1806-4841.20197335

    authors: Miolo N,Rodrigues RF,Silva ERD,Piati PK,Campagnolo OA,Marques LF

    更新日期:2019-03-01 00:00:00

  • The use of oxybutynin for treating facial hyperhidrosis.

    abstract:BACKGROUND:Facial hyperhidrosis is a disease that may lead patients to serious emotional disturbances. Video-assisted thoracic sympathectomy provides excellent resolution of facial hyperhidrosis, but is associated with certain complications. The most frequent and important complication is compensatory hyperhidrosis. Es...

    journal_title:Anais brasileiros de dermatologia

    pub_type: 临床试验,杂志文章

    doi:10.1590/s0365-05962011000300005

    authors: Wolosker N,Campos JR,Kauffman P,Munia MA,Neves S,Jatene FB,Puech-Leão P

    更新日期:2011-05-01 00:00:00

  • Scanning electron microscopy of granuloma annulare.

    abstract::Light microscopy of granuloma annulare shows mucin deposition with lympho-histiocytic infiltrate. We describe the ultrastructural three-dimensional aspects of a typical case of granuloma with characteristic histopathological findings. At the ultrastructural level, affected collagen bundles and granular mucin depositio...

    journal_title:Anais brasileiros de dermatologia

    pub_type: 杂志文章

    doi:10.1590/abd1806-4841.20187409

    authors: de Almeida HL Jr,Barros Coelho Bicca E,Andrade MM,Rocha Andrade Neto PD

    更新日期:2018-01-01 00:00:00

  • Translation into Portuguese language (Brazil), transcultural adaptation and validation of the quality of life questionnaire in female pattern hair loss (WAA-QoL-BP).

    abstract:BACKGROUND:Female pattern hair loss (FPHL) is a common complaint in adult women and inflicts major impact in quality of life, however, there is no specific questionnaire available in Portuguese for such evaluation. OBJECTIVES:Translation into Brazilian Portuguese, cultural adaptation and validation of the WAA-QoL (Wom...

    journal_title:Anais brasileiros de dermatologia

    pub_type: 杂志文章

    doi:10.1590/abd1806-4841.20187452

    authors: Machado Shimizu G,Wedy G,Schaefer L,Ramos P,Miot H

    更新日期:2018-01-01 00:00:00

  • Albinism: epidemiology, genetics, cutaneous characterization, psychosocial factors.

    abstract::Oculocutaneous albinism is an autosomal recessive disease caused by the complete absence or decrease of melanin biosynthesis in melanocytes. Due to the reduction or absence of melanin, albinos are highly susceptible to the harmful effects of ultraviolet radiation and are at increased risk of actinic damage and skin ca...

    journal_title:Anais brasileiros de dermatologia

    pub_type: 杂志文章,评审

    doi:10.1016/j.abd.2019.09.023

    authors: Marçon CR,Maia M

    更新日期:2019-01-01 00:00:00

  • Basal cell carcinoma with compromised margins: retrospective study of management, evolution, and prognosis.

    abstract:BACKGROUND:Non-melanoma skin cancer is the most common type of malignancy in the Western world, and surgical excision is the preferred approach. The approach adopted in the face of incomplete excisions of basal cell carcinoma is still controversial. OBJECTIVES:To compare the number of tumor recurrences after treatment...

    journal_title:Anais brasileiros de dermatologia

    pub_type: 杂志文章

    doi:10.1016/j.abd.2020.11.001

    authors: Fidelis MC,Stelini RF,Staffa LP,Moraes AM,Magalhães RF

    更新日期:2021-01-01 00:00:00

  • Extra ocular sebaceous adenocarcinoma in HIV-positive patient--case report.

    abstract::Sebaceous adenocarcinoma is a rare adnexal tumor that can affect the skin and is divided into ocular, a more common form and extra ocular, of a rarer occurrence. We report the case of a patient diagnosed with Acquired Immune Deficiency Syndrome (AIDS) who developed an extra ocular, bulky and fast-growing sebaceous ade...

    journal_title:Anais brasileiros de dermatologia

    pub_type: 杂志文章

    doi:10.1590/abd1806-4841.20132476

    authors: Menezes CK,Gomes NM,Jalkh AP,Franco Edos S,Martins TG

    更新日期:2013-11-01 00:00:00

  • Chromoblastomycosis associated with a lethal squamous cell carcinoma.

    abstract::Chromoblastomycosis is a subcutaneous mycosis caused by the dermatophytic fungi Fonsecaea, Phialophora and Cladophialophora. Usual complications include secondary infection, lymphedema and elephantiasis. Associated malignancies have been found in chronic cases. This case report describes a 72 year-old male with a 30 y...

    journal_title:Anais brasileiros de dermatologia

    pub_type: 杂志文章

    doi:10.1590/s0365-05962010000200025

    authors: Torres E,Beristain JG,Lievanos Z,Arenas R

    更新日期:2010-03-01 00:00:00

  • Histoplasmosis and AIDS co-infection.

    abstract::This report concerns an AIDS patient presenting systemic and cutaneous manifestations of histoplasmosis. A histopathological and mycological examination of the skin lesion confirmed the diagnosis. In AIDS patients histoplasmosis arises mainly when the T-CD4+ cell count is less than 50 cells/mm3. In such cases, histopl...

    journal_title:Anais brasileiros de dermatologia

    pub_type: 杂志文章

    doi:10.1590/s0365-05962011000500028

    authors: Orsi AT,Nogueira L,Chrusciak-Talhari A,Santos M,Ferreira LC,Talhari S,Talhari C

    更新日期:2011-09-01 00:00:00

  • Clouston syndrome associated with eccrine syringofibroadenoma.

    abstract::Eccrine syringofibroadenoma is a rare benign neoplasia derived from acrosyryngium cells of the eccrine sudoriferous glands. It affects the extremities of elderly individuals as solitary tumors, or may also present as multiple lesions. There are controversies about the pathogenesis and differentiation of the tumor. Ecc...

    journal_title:Anais brasileiros de dermatologia

    pub_type: 杂志文章

    doi:

    authors: Andrade AC,Vieira DC,Harris OM,Pithon MM

    更新日期:2014-05-01 00:00:00

  • Primary cutaneous histoplasmosis developed in the penis of an immunocompetent patient.

    abstract::A 70-year-old male presenting a 3-month history of genital painless erythematous nodules in the balanopreputial sulcus was referred to our service. Histopathological exam presented a chronic dermatitis with epithelioid granulomas and Grocott staining revealed numerous fungal structures with a suggestive morphology of ...

    journal_title:Anais brasileiros de dermatologia

    pub_type: 杂志文章

    doi:10.1590/abd1806-4841.20153224

    authors: Paixão M,Miot HA,Avancini J,Belda Júnior W

    更新日期:2015-03-01 00:00:00

  • Photodynamic therapy: a review of the literature and image documentation.

    abstract::Photodynamic therapy (PDT) consists of a chemical reaction activated by light energy that is used to selectively destroy tissue. The reaction requires a photosensitizer in the target tissue, a light source and oxygen. The most extensively studied photosensitizing agents for PDT are 5-aminolevulinic acid for the treatm...

    journal_title:Anais brasileiros de dermatologia

    pub_type: 杂志文章,评审

    doi:10.1590/s0365-05962010000400011

    authors: Issa MC,Manela-Azulay M

    更新日期:2010-07-01 00:00:00

  • Do you know this syndrome? POEMS syndrome.

    abstract::POEMS syndrome is a unique clinical entity, the diagnosis of which is made when polyneuropathy and monoclonal gammopathy occur together, associated with other changes such as organomegaly, endocrinopathy, skin changes and papilledema. Cutaneous manifestations are heterogeneous, with diffuse cutaneous hyperpigmentation...

    journal_title:Anais brasileiros de dermatologia

    pub_type: 杂志文章

    doi:10.1590/abd1806-4841.20132266

    authors: Santos G,Lestre S,João A

    更新日期:2013-11-01 00:00:00

  • Sarcoidosis simulating syringomas.

    abstract::Sarcoidosis is a granulomatous disease of unknown etiology. The skin is commonly affected. Cutaneous manifestations can mimic other diseases and autoimmune disorders. The dermatologist plays a critical role in elucidating the clinical diagnosis and assisting other specialists in the investigation of a systemic disease...

    journal_title:Anais brasileiros de dermatologia

    pub_type: 杂志文章

    doi:10.1590/s0365-05962012000200020

    authors: Rocha DS,Presotto C,Bringel DM,Bomm L,Balassiano E,Alves Mde F

    更新日期:2012-03-01 00:00:00

  • Eosinophilic annular erythema in adults: report of two cases and review of the literature.

    abstract::We herein report two cases of eosinophilic annular erythema in adults, which is rare. In both patients, lesions developed rapidly in few days and were located mainly on the trunk, buttocks, and extremities. Diagnosis was histopathological, with typical features including acute dermal inflammatory infiltrate with abund...

    journal_title:Anais brasileiros de dermatologia

    pub_type: 杂志文章,评审

    doi:10.1590/abd1806-4841.20176373

    authors: Heras MO,Muñoz NP,Sancho MI,Millet PU

    更新日期:2017-01-01 00:00:00

  • Pityriasis versicolor circinata: isolation of Malassezia sympodialis - Case report.

    abstract::The authors report a case of pityriasis versicolor circinata whose isolated etiologic agent was Malassezia sympodialis in a 34-year-old woman. The isolation and identification of Malassezia sympodialis were accomplished with modified Dixon's agar, and the molecular method used to confirm the species was polymerase cha...

    journal_title:Anais brasileiros de dermatologia

    pub_type: 杂志文章

    doi:10.1590/s0365-05962010000200015

    authors: Framil VM,Melhem MS,Szeszs MW,Corneta EC,Zaitz C

    更新日期:2010-03-01 00:00:00

  • Do you know this syndrome? Noonan syndrome.

    abstract::Noonan Syndrome is one of the most common genetic syndromes and also an important differential diagnosis in children presenting with syndromic facies similar to Turner's syndrome phenotype. This syndrome is characterized by facial dysmorphism, congenital heart defects, short stature and also a wide phenotypic variatio...

    journal_title:Anais brasileiros de dermatologia

    pub_type: 杂志文章

    doi:10.1590/abd1806-4841.20131934

    authors: Kondo RN,Martins LM,Lopes VC,Bittar RA,Araújo FM

    更新日期:2013-07-01 00:00:00

  • Vegetative chronic genital herpes with satisfactory response to imiquimod.

    abstract::Vegetative chronic genital herpes is an atypical presentation of herpes simplex 2 that it is usually seen in patients coinfected with human immunodeficiency virus. Clinically, it is characterized by extensive ulcers that evolve to chronification and hypertrophic pseudotumor forms. Antiviral drugs are recommended for t...

    journal_title:Anais brasileiros de dermatologia

    pub_type:

    doi:10.1590/abd1806-4841.20198014

    authors: Siqueira SM,Gonçalves BB,Loss JB,Estrella RR

    更新日期:2019-01-01 00:00:00

  • Serology with ML Flow test in health professionals from three different states of Brazil.

    abstract:BACKGROUND:In highly endemic countries, transmission and sub-clinical infection of leprosy are likely and the disease manifests itself in individuals without any known close contact with a leprosy patient. Health workers are social contacts belonging to the same network (the Health System) and some of them share the sa...

    journal_title:Anais brasileiros de dermatologia

    pub_type: 杂志文章

    doi:10.1590/abd1806-4841.20132139

    authors: Calado KL,Magnanini MM,Moura RS,Gallo ME,Bührer-Sékula S,Oliveira ML

    更新日期:2013-11-01 00:00:00

  • Presence of Candida spp. and candidiasis in liver transplant patients.

    abstract:BACKGROUND:Candidiasis is the most common opportunistic fungal infection of the oral cavity caused by fungi of the genus Candida and usually associated with immunosuppressed individuals. OBJECTIVES:To evaluate the presence of oral candidiasis and identify the presence of Candida spp. in liver transplant recipients and...

    journal_title:Anais brasileiros de dermatologia

    pub_type: 杂志文章

    doi:10.1590/abd1806-4841.20186533

    authors: Santos SBD,Sabadin CES,Mario DN,Rigo L,Barbosa DA

    更新日期:2018-06-01 00:00:00

  • Dermatomyositis: analysis of 109 patients surveyed at the Hospital das Clínicas (HCFMUSP), São Paulo, Brazil.

    abstract:BACKGROUND:Dermatomyositis affects striated muscles, skin and other organs. OBJECTIVE:To characterize the disease from January 1992 to December 2002, assessing its classification, cutaneous and systemic manifestations, and also laboratory results, therapeutic and prognostic findings compared to those in the literature...

    journal_title:Anais brasileiros de dermatologia

    pub_type: 杂志文章

    doi:10.1590/abd1806-4841.20143422

    authors: Ortigosa LC,Reis VM

    更新日期:2014-09-01 00:00:00

  • Cutaneous histoplasmosis disclosing an HIV-infection.

    abstract::Histoplasmosis is a systemic mycosis endemic in extensive areas of the Americas. The authors report on an urban adult male patient with uncommon oral-cutaneous lesions proven to be histoplasmosis. Additional investigation revealed unnoticed HIV infection with CD4+ cell count of 7/mm3. The treatment was performed with ...

    journal_title:Anais brasileiros de dermatologia

    pub_type: 杂志文章

    doi:10.1590/abd1806-4841.20131812

    authors: Marques SA,Silvares MR,Camargo RM,Marques ME

    更新日期:2013-05-01 00:00:00

  • Histopathological analysis of the therapeutic response to cryotherapy with liquid nitrogen in patients with multiple actinic keratosis.

    abstract::Actinic keratoses are premalignant lesions of the skin caused by excessive sun exposure. Lesions may become mainly squamous cell carcinoma. Cryotherapy with liquid nitrogen is one of the main treatments. In order to evaluate the response of actinic keratosis to cryotherapy by histopathology, two lesions were selected ...

    journal_title:Anais brasileiros de dermatologia

    pub_type: 杂志文章

    doi:10.1590/abd1806-4841.20153302

    authors: Oliveira MC,Trevisan F,Pinto CA,Xavier CA,Pinto JC

    更新日期:2015-05-01 00:00:00

  • Case for diagnosis: (Ectodermal dysplasia: Christ-Siemens-Touraine syndrome).

    abstract::Christ-Siemens-Touraine syndrome (hypohidrotic ectodermal dysplasia) is a rare syndrome characterized by the triad of absent or reduced sweating, hypotrichosis, and defective dentition. The prominent forehead, saddle nose, thick lower lip and pointy chin produce a distinctive facies. The full syndrome only occurs in m...

    journal_title:Anais brasileiros de dermatologia

    pub_type: 杂志文章

    doi:10.1590/s0365-05962009000200015

    authors: Succi IB,Fontenelle E

    更新日期:2009-03-01 00:00:00

  • A unique case of hereditary bilateral segmental neurofibromatosis on the face.

    abstract::Segmental neurofibromatosis is a rare clinical finding generally with no family history and facial involvement. There are four subtypes of segmental neurofibromatosis: true segmental, localized cases with deep involvement, hereditary segmental and bilateral segmental neurofibromatosis. Here we report three patients fr...

    journal_title:Anais brasileiros de dermatologia

    pub_type: 杂志文章

    doi:10.1590/s0365-05962012000600012

    authors: Jankovic I,Kovacevic P,Visnjic M,Jankovic D,Velickovic M

    更新日期:2012-11-01 00:00:00