Abstract:
BACKGROUND:The relationship between duration of cardiopulmonary resuscitation (CPR) and post-arrest outcomes based on severity stratification in out-of-hospital cardiac arrest (OHCA) patients without prehospital return of spontaneous circulation (ROSC) remains unclear. METHODS:We analysed 420,959 adult patients without prehospital ROSC in the All-Japan OHCA registry for 4 years. Prehospital CPR duration was defined as the time from CPR initiation by emergency medical service (EMS) providers to hospital arrival. The primary outcome was 1-month neurologically intact survival (cerebral performance category 1 or 2, CPC 1-2). RESULTS:The rate of overall 1-month CPC 1-2 was 0.45% (1899/420,959). Using recursive partitioning analysis to predict 1-month CPC 1-2, we stratified patients into 4 groups with 3 predictors: patients aged <75 years with initial shockable rhythm (1-month CPC 1-2 rate, 6.15%), those aged ≥75 years with initial shockable rhythm (1.32%), those with EMS-witnessed arrest and initial non-shockable rhythm (1.62%), and those with EMS-unwitnessed arrest and initial non-shockable rhythm (0.15%). Prehospital CPR duration was negatively associated with 1-month CPC 1-2 (adjusted odds ratio 0.94 per 1-min increment; 95% confidence interval 0.94-0.95). Prehospital CPR durations beyond which the dynamic probability of 1-month CPC 1-2 decreased to <1% were 26 min, 10 min, 7 min, and at all times in above-mentioned stratification, respectively. CONCLUSIONS:In OHCA patients without prehospital ROSC, those aged <75 years with initial shockable rhythm had acceptable 1-month CPC 1-2 rate. However, CPR efforts lasting 26 min or over before hospital arrival could be futile.
journal_name
Resuscitationjournal_title
Resuscitationauthors
Funada A,Goto Y,Tada H,Teramoto R,Shimojima M,Hayashi K,Kawashiri MA,Yamagishi Mdoi
10.1016/j.resuscitation.2018.01.008subject
Has Abstractpub_date
2018-03-01 00:00:00pages
69-75eissn
0300-9572issn
1873-1570pii
S0300-9572(18)30008-Xjournal_volume
124pub_type
杂志文章相关文献
RESUSCITATION文献大全abstract:PURPOSE:Airway management for successful ventilation by laypersons and inexperienced healthcare providers is difficult to achieve. Bag-valve mask (BVM) ventilation requires extensive training and is performed poorly. Supraglottic airway devices (SADs) have been successfully introduced to clinical resuscitation practice...
journal_title:Resuscitation
pub_type: 杂志文章,随机对照试验
doi:10.1016/j.resuscitation.2010.11.014
更新日期:2011-03-01 00:00:00
abstract:INTRODUCTION:Sudden cardiac death (SCD) survival decreases by 10% for each minute of delay in defibrillation, however, survival rates of 98% can be achieved when defibrillation is accomplished within 30s of collapse. Recently, a fully automated external cardioverter-defibrillator (AECD) was approved by the FDA for in-h...
journal_title:Resuscitation
pub_type: 杂志文章
doi:10.1016/j.resuscitation.2004.05.012
更新日期:2004-11-01 00:00:00
abstract::We compared plasma epinephrine levels after three different tracheal epinephrine application techniques and intravenous injection in male and female anesthetized and paralyzed domestic pigs. Epinephrine was administered intravenously (10 microg/kg) (group i.v.) or tracheally (100 microg/kg) either by direct injection ...
journal_title:Resuscitation
pub_type: 杂志文章
doi:10.1016/s0300-9572(98)00007-0
更新日期:1998-03-01 00:00:00
abstract:BACKGROUND:The electroencephalograph (EEG) pattern of burst suppression with identical bursts (BSIB), with or without myoclonus, occurs often after resuscitation from cardiac arrest. These patterns are associated with severe brain injury but their neuropathological basis is unknown. Using EEG source localization, we te...
journal_title:Resuscitation
pub_type: 杂志文章
doi:10.1016/j.resuscitation.2020.10.029
更新日期:2020-10-27 00:00:00
abstract::We evaluated the ability of a previously derived outcome predictor to discriminate between ECG segments corresponding to return of spontaneous circulation (ROSC) or not in validation data from 136 patients with cardiac arrest. The new data used for validation were totally independent from the predictor derivation data...
journal_title:Resuscitation
pub_type: 杂志文章
doi:10.1016/j.resuscitation.2005.05.006
更新日期:2005-10-01 00:00:00
abstract:AIM:The aim of this study was to calculate the incidence of out-of-hospital cardiac arrest (OHCA) in primary health care in Greece and assess general practitioners' (GPs) willingness towards the use of automatic external defibrillator (AED). METHODS:We conducted a survey in GPs working in both private and public secto...
journal_title:Resuscitation
pub_type: 杂志文章
doi:10.1016/j.resuscitation.2011.04.010
更新日期:2011-09-01 00:00:00
abstract:AIM:Early enteral nutrition (EN) is recommended for critically ill patients; however, few reports have examined early EN for patients who received targeted temperature management (TTM) after out-of-hospital cardiac arrest (OHCA). We investigated the effectiveness and safety of early EN for patients who received TTM aft...
journal_title:Resuscitation
pub_type: 杂志文章
doi:10.1016/j.resuscitation.2019.01.007
更新日期:2019-02-01 00:00:00
abstract::Cell-free DNA has been associated with outcome in several acute conditions including two reports concerning the outcomes after cardiac arrest that found association of circulating DNA quantities at admission with mortality. The origins of cell-free DNA are primarily necrosis and apoptosis, which in cardiac arrest occu...
journal_title:Resuscitation
pub_type: 杂志文章,多中心研究
doi:10.1016/j.resuscitation.2013.10.008
更新日期:2014-02-01 00:00:00
abstract:INTRODUCTION:The outcome after out of hospital cardiac arrest is dismal. Thrombolysis during CPR has been advocated. Our hypothesis was that early administration of bolus thrombolysis could lead to improved survival from out of hospital cardiac arrest. METHODS:A prospective, randomised, double blind placebo controlled...
journal_title:Resuscitation
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1016/j.resuscitation.2004.01.016
更新日期:2004-06-01 00:00:00
abstract:BACKGROUND:Out-of-hospital cardiac arrest (OHCA) initiates a chain of responses including emergency medical service mobilization and medical treatment, transfer and admission first to a hospital Emergency Department (ED) and then usually to an intensive care unit and ward. Costly pre- and in-hospital care may be follow...
journal_title:Resuscitation
pub_type: 杂志文章
doi:10.1016/j.resuscitation.2014.10.024
更新日期:2015-01-01 00:00:00
abstract:BACKGROUND:For out-of-hospital cardiac arrest (OHCA) to be predicted and prevented, it is imperative the healthcare system has access to those vulnerable before the event occurs. We aimed to determine the extent of contact to the healthcare system before OHCA. METHODS:All patients in Denmark with a registered OHCA Jun...
journal_title:Resuscitation
pub_type: 杂志文章,随机对照试验
doi:10.1016/j.resuscitation.2010.06.025
更新日期:2010-12-01 00:00:00
abstract:BACKGROUND:Demographic, social, economic and geographic factors are associated with increased short-term mortality after cardiac arrest. We sought to determine if these factors are additionally associated with long-term outcome differences using a detailed clinical database linked to state-wide administrative data. ME...
journal_title:Resuscitation
pub_type: 杂志文章,多中心研究
doi:10.1016/j.resuscitation.2018.04.032
更新日期:2018-07-01 00:00:00
abstract:AIM:Survival after out-of-hospital cardiac arrest (OOHCA) varies between regions, but the contribution of different factors to this variability is unknown. This study examined whether survival to hospital discharge was related to receiving hospital characteristics, including bed number, capability of performing cardiac...
journal_title:Resuscitation
pub_type: 杂志文章
doi:10.1016/j.resuscitation.2009.12.006
更新日期:2010-05-01 00:00:00
abstract::The quality of education, CPR guidelines and the chain of survival all contribute to patient outcome following cardiac arrest. Increasing concerns about patient safety have focused attention on the methods used to train and prepare doctors for clinical practice. Reductions in clinical exposure at both undergraduate an...
journal_title:Resuscitation
pub_type: 杂志文章,评审
doi:10.1016/j.resuscitation.2007.01.005
更新日期:2007-05-01 00:00:00
abstract:BACKGROUND:The epidemiology and outcome after out-of-hospital cardiac arrest (OHCA) varies across Europe. Following on from EuReCa ONE, the aim of this study was to further explore the incidence of and outcomes from OHCA in Europe and to improve understanding of the role of the bystander. METHODS:This prospective, mul...
journal_title:Resuscitation
pub_type: 杂志文章
doi:10.1016/j.resuscitation.2019.12.042
更新日期:2020-03-01 00:00:00
abstract:AIM:The whole body ischaemia-reperfusion after cardiac arrest (CA) induces a systemic inflammation-reperfusion response. The expression of urokinase plasminogen activator receptor (uPAR) is known to be induced after hypoxia and increased levels of soluble form suPAR have been measured after hypoxia and ischaemia. Our a...
journal_title:Resuscitation
pub_type: 杂志文章
doi:10.1016/j.resuscitation.2014.08.017
更新日期:2014-11-01 00:00:00
abstract:AIM:To date, no clinical test is able to predict cognitive and functional outcome of cardiac arrest survivors. Improvement of auditory discrimination in acute coma indicates survival with high specificity. Whether the degree of this improvement is indicative of recovery remains unknown. Here we investigated if progress...
journal_title:Resuscitation
pub_type: 杂志文章
doi:10.1016/j.resuscitation.2016.06.032
更新日期:2016-09-01 00:00:00
abstract:AIM OF THE STUDY:The 1-day immediate life support course (ILS) was started in the United Kingdom and adopted by the ERC to train healthcare professionals who attend cardiac arrests only occasionally. Currently, there are no reports about the ILS course from outside the UK. In this paper we describe our initial Italian ...
journal_title:Resuscitation
pub_type: 杂志文章
doi:10.1016/j.resuscitation.2006.07.024
更新日期:2007-03-01 00:00:00
abstract:AIM:In out of hospital cardiac arrest (OHCA) the start of Cardiopulmonary Resuscitation (CPR) by a single rescuer may be delayed considerably if the total time (TT) to connect the telephone call to the Emergency Medical Communication Centre (EMCC) is prolonged. EUROCALL investigated the TT-EMCC and its components using...
journal_title:Resuscitation
pub_type: 杂志文章,多中心研究,随机对照试验
doi:10.1016/j.resuscitation.2016.10.026
更新日期:2017-02-01 00:00:00
abstract:AIM OF STUDY:High-quality CPR is associated with improved outcomes from out-of-hospital cardiac arrest (OHCA). The purpose of this investigation was to compare the quality of CPR provided at the prehospital scene, during ambulance transport, and during the early minutes in the emergency department (ED). METHODS:A pros...
journal_title:Resuscitation
pub_type: 杂志文章
doi:10.1016/j.resuscitation.2012.07.042
更新日期:2013-05-01 00:00:00
abstract::Up to 90% of cardiac arrests are due to acute myocardial infarction or severe myocardial ischaemia. Thrombolysis is an effective treatment for ST-elevation myocardial infarction (STEMI), but there is no evidence or guideline to put forward a thrombolysis strategy during cardiopulmonary resuscitation (CPR). In two phys...
journal_title:Resuscitation
pub_type: 杂志文章,多中心研究
doi:10.1016/j.resuscitation.2007.07.012
更新日期:2008-02-01 00:00:00
abstract:OBJECTIVE:During normovolaemic haemodilution arterial O(2)-content decreases exponentially. Nevertheless, tissue oxygenation is first maintained initially by increased organ perfusion and O(2)-extraction. As soon as these compensatory mechanisms are exhausted, myocardial ischaemia and tissue hypoxia occur at an individ...
journal_title:Resuscitation
pub_type: 杂志文章
doi:10.1016/s0300-9572(02)00408-2
更新日期:2003-03-01 00:00:00
abstract:BACKGROUND:Early defibrillation clearly improves survival from malignant arrhythmia. However, in some cases the cause of death will only be altered from arrhythmic to nonarrhythmic. We evaluated the impact of left ventricular ejection fraction (LVEF) on trend and recovery profile of beat-to-beat cardiac output (CO) and...
journal_title:Resuscitation
pub_type: 杂志文章
doi:10.1016/j.resuscitation.2010.06.004
更新日期:2010-09-01 00:00:00
abstract:INTRODUCTION:The current guidelines of the European Resuscitation Council (ERC) stipulate that an intraosseous access should be placed if establishing a peripheral venous access for cardiopulmonary resuscitation (CPR) would involve delays. The aim of this study was therefore to compare a manual intraosseous infusion te...
journal_title:Resuscitation
pub_type: 杂志文章,随机对照试验
doi:10.1016/j.resuscitation.2008.04.004
更新日期:2008-09-01 00:00:00
abstract:INTRODUCTION:The CAREvent Public Access Resuscitator (PAR, O-Two Medical Technologies, Ontario, Canada) is a new oxygen-driven device alternating two ventilations with 15 prompts for chest compressions. The PAR is designed for use with a standard resuscitation face mask and is equipped with mask leakage and obstruction...
journal_title:Resuscitation
pub_type: 杂志文章
doi:10.1016/j.resuscitation.2005.04.012
更新日期:2005-10-01 00:00:00
abstract::Using the stable xenon-enhanced computed tomography (Xe-CT) method in dogs, we studied local, regional and global cerebral blood flow (LCBF, rCBF and gCBF) in two sham experiments and nine cardiac arrest experiments. Within the same experiments without arrest, gCBF and rCBF values were reproducible and stable. LCBF va...
journal_title:Resuscitation
pub_type: 杂志文章
doi:10.1016/0300-9572(92)90171-8
更新日期:1992-08-01 00:00:00
abstract:AIM:We examined the relationship between time from collapse to arrival of emergency medical services (EMS) and survival to hospital discharge for out-of-hospital ventricular fibrillation cardiac arrests in order to determine meaningful interpretations of this association. METHODS:We calculated survival rates in 1-min ...
journal_title:Resuscitation
pub_type: 杂志文章
doi:10.1016/j.resuscitation.2010.02.004
更新日期:2010-05-01 00:00:00
abstract:PURPOSE:Mechanical chest compression devices, such as the AutoPulse(®), have been developed to overcome problems associated with manual CPR (M-CPR). Animal and human studies have shown that AutoPulse CPR improves hemodynamic parameters over M-CPR. However, human studies conducted in the prehospital setting have conflic...
journal_title:Resuscitation
pub_type: 杂志文章,多中心研究,随机对照试验
doi:10.1016/j.resuscitation.2010.11.013
更新日期:2011-03-01 00:00:00
abstract:OBJECTIVE:Evaluate the prevalence of fever in the first 48 h after cardiac arrest and its effect on outcomes. METHODS:Review of patients treated between 1/1/2005 and 6/30/2010. Fever was defined as T ≥ 38.0°C. We classified categories of post-cardiac arrest illness severity as (I) awake, (II) coma+mild cardiopulmonary...
journal_title:Resuscitation
pub_type: 杂志文章
doi:10.1016/j.resuscitation.2013.03.038
更新日期:2013-08-01 00:00:00
abstract::The purpose of this study was to compare the rewarming effectiveness of a radio frequency coil (13.56 MHz) at a specific absorption rate (SAR) of 2.5 W/kg (RF) with warm water immersion (40 degrees C) (WW) and an insulated mummy-type insulating sack (IS) under simulated field conditions. Four male subjects, ages 24-35...
journal_title:Resuscitation
pub_type: 临床试验,杂志文章
doi:10.1016/0300-9572(94)00845-7
更新日期:1995-06-01 00:00:00