Outcomes of rescue cardiopulmonary support for periprocedural acute hemodynamic decompensation in patients undergoing catheter ablation of electrical storm.


BACKGROUND:In patients with ventricular tachycardia or ventricular fibrillation (VT/VF) electrical storm (ES) undergoing catheter ablation (CA), hypotension due to refractory VT/VF, use of anesthesia, and cardiac stunning due to repeated implantable cardioverter-defibrillator shocks might precipitate acute hemodynamic decompensation (AHD). OBJECTIVE:We evaluated the outcomes of emergent cardiopulmonary support with extracorporeal membrane oxygenation (ECMO) to rescue AHD in patients undergoing CA of ES. METHODS:Between January 1, 2010 and December 31, 2016, 21 patients with ES (VT in 11 and premature ventricular complex-triggered VF in 10) were referred for CA and had periprocedural AHD requiring emergent ECMO support. RESULTS:In 14 patients, AHD occurred a mean of 1.5 ± 1.7 days before the procedure. In the remaining 7 patients, AHD occurred during or shortly after the procedure. ECMO was started successfully in all patients. Ablation was performed in 18 patients (9 with VF and 9 with VT). In patients with VF, premature ventricular complex suppression was achieved in 8 of 9 (89%). In those with VT, noninducibility was achieved in 7 of 9 (78%). After a median follow-up of 10 days, 16 patients died (13 during the index admission). Death was due to refractory VT/VF in 4 patients, heart failure in 11, and noncardiac cause in 1 patient. Seven patients survived beyond 6 months postablation; 5 remained free of VT/VF and 3 ultimately received a destination therapy (heart transplantation in 2 and left ventricular [LV] assist device in 1). CONCLUSION:In patients with ES undergoing CA, the outcomes of ECMO support as rescue intervention for AHD are poor. The majority of these patients die of refractory heart failure in the short-term. Strategies to prevent AHD including preemptive use of hemodynamic support may improve survival.


Heart Rhythm


Heart rhythm


Enriquez A,Liang J,Gentile J,Schaller RD,Supple GE,Frankel DS,Garcia FC,Wald J,Birati EY,Rame JE,Bermudez C,Callans DJ,Marchlinski FE,Santangeli P




Has Abstract


2018-01-01 00:00:00














  • Bidirectional ventricular tachycardia: ping pong in the His-Purkinje system.

    abstract:BACKGROUND:Bidirectional ventricular tachycardia (BVT), which is characterized by an alternating beat-to-beat ECG QRS axis, is a rare but intriguing arrhythmia associated with digitalis toxicity, familial catecholaminergic polymorphic ventricular tachycardia (CPVT), and several other conditions that predispose cardiac ...

    journal_title:Heart rhythm

    pub_type: 杂志文章


    authors: Baher AA,Uy M,Xie F,Garfinkel A,Qu Z,Weiss JN

    更新日期:2011-04-01 00:00:00

  • Bodyweight fluctuation is associated with increased risk of incident atrial fibrillation.

    abstract:BACKGROUND:Obesity and weight gain are established risk factors for atrial fibrillation (AF). OBJECTIVE:The purpose of this study was to investigate whether bodyweight variability is also a risk factor for AF development. METHODS:A nationwide population-based cohort of 8,091,401 adults from the Korean National Health...

    journal_title:Heart rhythm

    pub_type: 杂志文章


    authors: Lee HJ,Choi EK,Han KD,Lee E,Moon I,Lee SR,Cha MJ,Oh S,Lip GYH

    更新日期:2020-03-01 00:00:00

  • Effect of spatial resolution and filtering on mapping cardiac fibrillation.

    abstract:BACKGROUND:Endocardial mapping tools use variable interelectrode resolution, whereas body surface mapping tools use narrow bandpass filtering (BPF) to map fibrillatory mechanisms established by high-resolution optical imaging. OBJECTIVE:The purpose of this study was to study the effect of resolution and BPF on the und...

    journal_title:Heart rhythm

    pub_type: 杂志文章


    authors: King B,Porta-Sánchez A,Massé S,Zamiri N,Balasundaram K,Kusha M,Jackson N,Haldar S,Umapathy K,Nanthakumar K

    更新日期:2017-04-01 00:00:00

  • Minimally invasive transtracheal cardiac plexus block for sympathetic neuromodulation.

    abstract:BACKGROUND:Bilateral thoracoscopic stellectomy has antiarrhythmic effects, but the procedure is invasive with associated morbidity. Sympathetic nerves from both stellate ganglia form the deep cardiac plexus (CP) in the aortopulmonary window, anterior to the trachea. OBJECTIVE:The purpose of this study was to demonstra...

    journal_title:Heart rhythm

    pub_type: 杂志文章


    authors: Assis FR,Yu DH,Zhou X,Sidhu S,Bapna A,Engelman ZJ,Misra S,Okada DR,Chrispin J,Berger R,Mandal K,Lee H,Tandri H

    更新日期:2019-01-01 00:00:00

  • Classifying fractionated electrograms in human atrial fibrillation using monophasic action potentials and activation mapping: evidence for localized drivers, rate acceleration, and nonlocal signal etiologies.

    abstract:BACKGROUND:Complex fractionated electrograms (CFAEs) detected during substrate mapping for atrial fibrillation (AF) reflect etiologies that are difficult to separate. Without knowledge of local refractoriness and activation sequence, CFAEs may represent rapid localized activity, disorganized wave collisions, or far-fie...

    journal_title:Heart rhythm

    pub_type: 杂志文章


    authors: Narayan SM,Wright M,Derval N,Jadidi A,Forclaz A,Nault I,Miyazaki S,Sacher F,Bordachar P,Clémenty J,Jaïs P,Haïssaguerre M,Hocini M

    更新日期:2011-02-01 00:00:00

  • Acute biventricular hemodynamic effects of cardiac resynchronization therapy in right bundle branch block.

    abstract:BACKGROUND:Controversy remains regarding the use of cardiac resynchronization therapy (CRT) in patients with heart failure with right bundle branch block (RBBB) and reduced left ventricular (LV) ejection fraction. Moreover, little is known about acute hemodynamic changes with CRT in this subgroup as compared with patie...

    journal_title:Heart rhythm

    pub_type: 杂志文章,多中心研究


    authors: Houston BA,Sturdivant JL,Yu Y,Gold MR

    更新日期:2018-10-01 00:00:00

  • High-density epicardial mapping of the pulmonary vein-left atrial junction in humans: insights into mechanisms of pulmonary vein arrhythmogenesis.

    abstract:BACKGROUND:The pulmonary veins (PVs) and the PV-LA (left atrium) junction are established sources of triggers initiating atrial fibrillation. In addition, they have been implicated in the maintenance of arrhythmia. OBJECTIVE:To undertake high-density electrophysiological characterization of the right superior PV-LA ju...

    journal_title:Heart rhythm

    pub_type: 杂志文章


    authors: Lee G,Spence S,Teh A,Goldblatt J,Larobina M,Atkinson V,Brown R,Morton JB,Sanders P,Kistler PM,Kalman JM

    更新日期:2012-02-01 00:00:00

  • Improving long QT syndrome diagnosis by a polynomial-based T-wave morphology characterization.

    abstract:BACKGROUND:Diagnosing long QT syndrome (LQTS) remains challenging because of a considerable overlap in QT interval between patients with LQTS and healthy subjects. Characterizing T-wave morphology might improve LQTS diagnosis. OBJECTIVE:The purpose of this study was to improve LQTS diagnosis by combining new polynomia...

    journal_title:Heart rhythm

    pub_type: 杂志文章


    authors: Hermans BJM,Bennis FC,Vink AS,Koopsen T,Lyon A,Wilde AAM,Nuyens D,Robyns T,Pison L,Postema PG,Delhaas T

    更新日期:2020-05-01 00:00:00

  • Temporary autonomic modulation with botulinum toxin type A to reduce atrial fibrillation after cardiac surgery.

    abstract:BACKGROUND:Postoperative atrial fibrillation (POAF) frequently complicates cardiac surgery and is associated with worse outcomes. The cardiac autonomic nervous system is implicated in the pathogenesis of POAF. OBJECTIVE:The purpose of this study was to determine the efficacy and safety of selective cardiac autonomic m...

    journal_title:Heart rhythm

    pub_type: 杂志文章,多中心研究,随机对照试验


    authors: Waldron NH,Cooter M,Haney JC,Schroder JN,Gaca JG,Lin SS,Sigurdsson MI,Fudim M,Podgoreanu MV,Stafford-Smith M,Milano CA,Piccini JP,Mathew JP

    更新日期:2019-02-01 00:00:00

  • Prolonged atrial refractoriness predicts the onset of atrial fibrillation: A 12-year follow-up study.

    abstract:BACKGROUND:Tissue refractoriness to conduction is a crucial electrophysiological factor in determining susceptibility to fibrillation. The relationship between atrial refractoriness and future onset of atrial fibrillation (AF) has not been well studied. OBJECTIVES:We investigated whether atrial effective refractory pe...

    journal_title:Heart rhythm

    pub_type: 杂志文章


    authors: Lee JM,Lee H,Janardhan AH,Park J,Joung B,Pak HN,Lee MH,Kim SS,Hwang HJ

    更新日期:2016-08-01 00:00:00

  • Predicted longevity of contemporary cardiac implantable electronic devices: A call for industry-wide "standardized" reporting.

    abstract:BACKGROUND:Battery longevity is an important factor that may influence the selection of cardiac implantable electronic devices (CIEDs). However, there remains a lack of industry-wide standardized reporting of predicted CIED longevity to facilitate informed decision-making for implanting physicians and payers. OBJECTIV...

    journal_title:Heart rhythm

    pub_type: 杂志文章


    authors: Munawar DA,Mahajan R,Linz D,Wong GR,Khokhar KB,Thiyagarajah A,Kadhim K,Emami M,Mishima R,Elliott AD,Middeldorp ME,Roberts-Thompson KC,Young GD,Sanders P,Lau DH

    更新日期:2018-12-01 00:00:00

  • A common missense variant in the neuregulin 1 gene is associated with both schizophrenia and sudden cardiac death.

    abstract:BACKGROUND:Both schizophrenia and epilepsy have been linked to increased risk of sudden cardiac death (SCD). We hypothesized that DNA variants within genes previously associated with schizophrenia and epilepsy may contribute to an increased risk of SCD. OBJECTIVE:To investigate the contribution to SCD susceptibility o...

    journal_title:Heart rhythm

    pub_type: 杂志文章,多中心研究


    authors: Huertas-Vazquez A,Teodorescu C,Reinier K,Uy-Evanado A,Chugh H,Jerger K,Ayala J,Gunson K,Jui J,Newton-Cheh C,Albert CM,Chugh SS

    更新日期:2013-07-01 00:00:00

  • Comparative spatial resolution of 12-lead electrocardiography and an automated algorithm.

    abstract:BACKGROUND:The spatial resolution of pacemapping using 12-lead electrocardiography (ECG) or PaSo software is unknown. OBJECTIVE:The purpose of this study was to determine the spatial resolution of traditional ECG pacemapping and pacemapping using the PaSo coefficients. METHODS:Seventeen patients undergoing ablation o...

    journal_title:Heart rhythm

    pub_type: 杂志文章


    authors: Dharmaprani D,Lahiri A,Ganesan AN,Kyriacou N,McGavigan AD

    更新日期:2020-02-01 00:00:00

  • Validation of a defibrillation lead ventricular volume measurement compared to three-dimensional echocardiography.

    abstract:BACKGROUND:There is increasing evidence that using frequent invasive measures of pressure in patients with heart failure results in improved outcomes compared to traditional measures. Admittance, a measure of volume derived from preexisting defibrillation leads, is proposed as a new technique to monitor cardiac hemodyn...

    journal_title:Heart rhythm

    pub_type: 临床试验,杂志文章


    authors: Haines DE,Wong W,Canby R,Jewell C,Houmsse M,Pederson D,Sugeng L,Porterfield J,Kottam A,Pearce J,Valvano J,Michalek J,Trevino A,Sagar S,Feldman MD

    更新日期:2017-10-01 00:00:00

  • Outcomes of His-bundle pacing upgrade after long-term right ventricular pacing and/or pacing-induced cardiomyopathy: Insights into disease progression.

    abstract:BACKGROUND:His-bundle pacing (HBP) is a physiological alternative to right ventricular pacing (RVP). The outcomes of HBP in patients with longstanding atrioventricular block (AVB) and RVP are unknown OBJECTIVE: The purpose of this study was to retrospectively assess the feasibility of HBP in patients with chronic RVP a...

    journal_title:Heart rhythm

    pub_type: 杂志文章,多中心研究


    authors: Vijayaraman P,Herweg B,Dandamudi G,Mittal S,Bhatt AG,Marcantoni L,Naperkowski A,Sharma PS,Zanon F

    更新日期:2019-10-01 00:00:00

  • Probability and magnitude of response to cardiac resynchronization therapy according to QRS duration and gender in nonischemic cardiomyopathy and LBBB.

    abstract:BACKGROUND:QRS morphology and QRS duration (QRSd) determine cardiac resynchronization therapy (CRT) candidate selection but criteria require refinement. OBJECTIVE:To assess CRT effect according to QRSd, treated by dichotomization vs a continuous function, and modulation by gender. METHODS:Patients selected were those...

    journal_title:Heart rhythm

    pub_type: 杂志文章


    authors: Varma N,Manne M,Nguyen D,He J,Niebauer M,Tchou P

    更新日期:2014-07-01 00:00:00

  • Vagal activity modulates spontaneous augmentation of J-wave elevation in patients with idiopathic ventricular fibrillation.

    abstract:BACKGROUND:Although J-wave elevation in the inferolateral leads could be related to idiopathic ventricular fibrillation (IVF), little is known about the pathophysiologic characteristics of J-wave elevation in patients with IVF. OBJECTIVE:This study aimed to determine the relationship between augmentation of J-wave ele...

    journal_title:Heart rhythm

    pub_type: 杂志文章


    authors: Mizumaki K,Nishida K,Iwamoto J,Nakatani Y,Yamaguchi Y,Sakamoto T,Tsuneda T,Kataoka N,Inoue H

    更新日期:2012-02-01 00:00:00

  • Does the number of simultaneously activated electrodes during phased RF multielectrode ablation of atrial fibrillation influence the incidence of silent cerebral microembolism?

    abstract:BACKGROUND:Asymptomatic cerebral embolus (ACE) detected by diffusion-weighted magnetic resonance imaging (DW-MRI) following atrial fibrillation (AF) ablation has been reported at varying rates with different ablation techniques. OBJECTIVE:To evaluate the incidence of ACE after phased radiofrequency ablation for AF wit...

    journal_title:Heart rhythm

    pub_type: 杂志文章,随机对照试验


    authors: Wieczorek M,Hoeltgen R,Brueck M

    更新日期:2013-07-01 00:00:00

  • Electrolyte disturbances differentially regulate sinoatrial node and pulmonary vein electrical activity: A contribution to hypokalemia- or hyponatremia-induced atrial fibrillation.

    abstract:BACKGROUND:Hypokalemia and hyponatremia increase the occurrence of atrial fibrillation. Sinoatrial nodes (SANs) and pulmonary veins (PVs) play a critical role in the pathophysiology of atrial fibrillation. OBJECTIVE:The purpose of this study was to evaluate whether electrolyte disturbances with low concentrations of p...

    journal_title:Heart rhythm

    pub_type: 杂志文章


    authors: Lu YY,Cheng CC,Chen YC,Lin YK,Chen SA,Chen YJ

    更新日期:2016-03-01 00:00:00

  • Relationship between the electrocardiographic atrial fibrillation cycle length and left atrial remodeling: a detailed electroanatomic mapping study.

    abstract:BACKGROUND/OBJECTIVE:The purpose of this study was to characterize the association between the extent of left atrial electroanatomic remodeling in atrial fibrillation and the atrial fibrillation cycle length derived from lead V₁ of the surface ECG (V1AFCL). METHODS:Twenty-three patients in atrial fibrillation (AF) who...

    journal_title:Heart rhythm

    pub_type: 杂志文章


    authors: Walters TE,Teh AW,Spence S,Kistler PM,Morton JB,Kalman JM

    更新日期:2014-04-01 00:00:00

  • Automated analysis of atrial late gadolinium enhancement imaging that correlates with endocardial voltage and clinical outcomes: a 2-center study.

    abstract:BACKGROUND:For late gadolinium enhancement (LGE) cardiovascular magnetic resonance (CMR) assessment of atrial scar to guide management and targeting of ablation in atrial fibrillation (AF), an objective, reproducible method of identifying atrial scar is required. OBJECTIVE:To describe an automated method for operator-...

    journal_title:Heart rhythm

    pub_type: 杂志文章,多中心研究


    authors: Malcolme-Lawes LC,Juli C,Karim R,Bai W,Quest R,Lim PB,Jamil-Copley S,Kojodjojo P,Ariff B,Davies DW,Rueckert D,Francis DP,Hunter R,Jones D,Boubertakh R,Petersen SE,Schilling R,Kanagaratnam P,Peters NS

    更新日期:2013-08-01 00:00:00

  • Identification of "substrate fibrillators" and "trigger fibrillators" by pacemaker diagnostics.

    abstract:BACKGROUND:The population of patients likely to respond to selected pacing algorithms for maintenance of sinus rhythm is unknown. OBJECTIVES:The purpose of this study was to identify patients with specific onset patterns of paroxysmal atrial fibrillation (AF). METHODS:Dual-chamber pacemakers with advanced diagnostic ...

    journal_title:Heart rhythm

    pub_type: 杂志文章


    authors: Yang A,Ruiter J,Pfeiffer D,Esmailzadeh B,Welz A,Hochhäusler M,Nickenig G,Lüderitz B,Lewalter T

    更新日期:2006-06-01 00:00:00

  • Long-term omega-3 polyunsaturated fatty acid supplementation reduces the recurrence of persistent atrial fibrillation after electrical cardioversion.

    abstract:BACKGROUND:Persistent atrial fibrillation (AF) is associated with a high risk of recurrence after electrical cardioversion. OBJECTIVE:We examined if long-term supplementation with omega-3 polyunsaturated fatty acids in fish oils commenced >1 month prior to electrical cardioversion and continued thereafter reduces recu...

    journal_title:Heart rhythm

    pub_type: 杂志文章,随机对照试验


    authors: Kumar S,Sutherland F,Morton JB,Lee G,Morgan J,Wong J,Eccleston DE,Voukelatos J,Garg ML,Sparks PB

    更新日期:2012-04-01 00:00:00

  • Outcomes of patients admitted with ventricular arrhythmias and sudden cardiac death in the United States.

    abstract:BACKGROUND:Mortality caused by ventricular arrhythmias (VAs) remains a problem of epidemic proportions. Understanding current trends on admission of VA, patient characteristics, morbidity, mortality, and health care utilization could help us improve allocation of health care resources and risk prediction. OBJECTIVE:Th...

    journal_title:Heart rhythm

    pub_type: 杂志文章


    authors: Viles-Gonzalez JF,Arora S,Deshmukh A,Atti V,Agnihotri K,Patel N,Dave M,Anter E,Garcia F,Santangeli P,Goldberger JJ,Dukkipati S,d'Avila A,Natale A,Di Biase L

    更新日期:2019-03-01 00:00:00

  • Combined epicardial and endocardial ablation for atrial fibrillation: Best practices and guide to hybrid convergent procedures.

    abstract::The absence of strategies to consistently and effectively address nonparoxysmal atrial fibrillation by nonpharmacological interventions has represented a long-standing treatment gap. A combined epicardial/endocardial ablation strategy, the hybrid Convergent procedure, was developed in response to this clinical need. A...

    journal_title:Heart rhythm

    pub_type: 杂志文章


    authors: Makati KJ,Sood N,Lee LS,Yang F,Shults CC,DeLurgio DB,Melichercik J,Gill JS,Kaba RA,Ahsan S,Weerasooriya R,Joshi P,Lellouche N,Blaauw Y,Zannis K,Sebag FA,Gauri A,Zembala MO,Tondo C,Steinberg JS

    更新日期:2020-10-09 00:00:00

  • Atrial Fibrillation is an Independent Predictor for In-hospital Mortality in Patients Admitted with SARS-CoV-2 Infection.

    abstract:BACKGROUND:Atrial fibrillation (AF) is the most encountered arrhythmia and has been associated with worse in-hospital outcomes. OBJECTIVE:To determine the incidence of AF among patients hospitalized with COVID-19 as well as its impact on in-hospital mortality. METHODS:Patients hospitalized with a positive COVID-19 po...

    journal_title:Heart rhythm

    pub_type: 杂志文章


    authors: Mountantonakis SE,Saleh M,Fishbein J,Gandomi A,Lesser M,Chelico J,Gabriels J,Qiu M,Epstein LM,Northwell COVID-19 Research Consortium.

    更新日期:2021-01-22 00:00:00

  • Ablation for longstanding permanent atrial fibrillation: results from a randomized study comparing three different strategies.

    abstract:BACKGROUND:This prospective multicenter randomized study aimed to compare the efficacy of 3 common ablation methods used for longstanding permanent atrial fibrillation (AF). METHODS:A total of 144 patients with longstanding permanent AF (median duration 28 months) were randomly assigned to circumferential pulmonary ve...

    journal_title:Heart rhythm

    pub_type: 杂志文章,多中心研究,随机对照试验


    authors: Elayi CS,Verma A,Di Biase L,Ching CK,Patel D,Barrett C,Martin D,Rong B,Fahmy TS,Khaykin Y,Hongo R,Hao S,Pelargonio G,Dello Russo A,Casella M,Santarelli P,Potenza D,Fanelli R,Massaro R,Arruda M,Schweikert RA,Nata

    更新日期:2008-12-01 00:00:00

  • Pediatric survivors of out-of-hospital ventricular fibrillation: Etiologies and outcomes.

    abstract:BACKGROUND:In general, the prognosis is poor for pediatric patients who experience out-of-hospital (OOH) cardiac arrest, with survival rates of 12% to 29%. OBJECTIVE:The purpose of this study was to describe the causes and outcomes of pediatric patients with documented ventricular fibrillation (VF) at resuscitation fr...

    journal_title:Heart rhythm

    pub_type: 杂志文章


    authors: Silka MJ,Kobayashi RL,Hill AC,Bar-Cohen Y

    更新日期:2018-01-01 00:00:00

  • Characteristics of ectopic triggers associated with paroxysmal and persistent atrial fibrillation: evidence for a changing role.

    abstract:BACKGROUND:Atrial premature contractions (APCs) are well described to precede the initiation of paroxysmal atrial fibrillation (pAF). However, whether APC characteristics alter with progression of the arrhythmia is unknown. OBJECTIVE:To determine the APC characteristics in terms of burden and relative coupling interva...

    journal_title:Heart rhythm

    pub_type: 杂志文章


    authors: Brooks AG,Rangnekar G,Ganesan AN,Salna I,Middeldorp ME,Kuklik P,Baumert M,Roberts-Thomson KC,Sanders P

    更新日期:2012-09-01 00:00:00

  • Insulin-like growth factor-binding protein 7 and risk of congestive heart failure hospitalization in patients with atrial fibrillation.

    abstract:BACKGROUND:The occurrence of congestive heart failure (CHF) hospitalization among patients with atrial fibrillation (AF) is a poor prognostic marker. OBJECTIVE:The purpose of this study was to assess whether insulin-like growth factor-binding protein 7 (IGFBP-7), a marker of myocardial damage, identifies AF patients a...

    journal_title:Heart rhythm

    pub_type: 杂志文章


    authors: Blum S,Aeschbacher S,Meyre P,Kühne M,Rodondi N,Beer JH,Ammann P,Moschovitis G,Bonati LH,Blum MR,Kastner P,Baguley F,Sticherling C,Osswald S,Conen D,BEAT-AF and Swiss-AF Investigators.

    更新日期:2020-12-03 00:00:00