Abstract：
:The short-term (30 days) effects of lithium carbonate on ADH secretion, urinary enzyme secretion (specific markers of tubular damage), fractional excretion of sodium, calcaemia, calciuria and fractional reabsorption of phosphate, plasma and urinary Ca, urea and creatinine clearance were assessed in 15 female patients with emotional disorders. An immediate increase in diuresis was noted. At least in the acute initial phase, this phenomenon appears to be caused by inhibited ADH incretion. No significant variation were noted in calciuria or the fraction of sodium secretion but there was a significant increase of enzymuria, confirming the potential nephrotoxicity of lithium treatment.
journal_name
Minerva Medjournal_title
Minerva medicaauthors
Palla R,Galigani P,Marchitiello M,Tuoni M,Lenzi A,Placidi GFsubject
Has Abstractpub_date
1986-02-28 00:00:00pages
205-8issue
7-8eissn
0026-4806issn
1827-1669journal_volume
77pub_type
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