Abstract：
:In the present work receptors for polymerized rat serum albumin (P-RSA) were studied by incubation of radiolabelled polymers with rat hepatocytes isolated with mechanical techniques. Isolated rat hepatocytes showed a receptor activity for polymerized albumin and such a membrane receptor seems to be controlled by the cellular cytoskeleton. During rat total body scintigraphy receptor expression was detected exclusively in the liver. These observations support the hypothesis of a selective receptor activity of the liver cells for polymerized albumin. To confirm our results, further studies were performed on rat bile, after 125I-P-RSA infusion in vivo.
journal_name
Minerva Medjournal_title
Minerva medicaauthors
Trevisan A,Cavigli R,Stenico D,Casara D,Pasquali C,Capri Csubject
Has Abstractpub_date
1988-02-01 00:00:00pages
81-90issue
2eissn
0026-4806issn
1827-1669journal_volume
79pub_type
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