Abstract:
BACKGROUND:Despite many advances in surgery and technology, colonic anastomosis remains a challenge after colonic resection. The purpose of this study is to compare the safety of using diclofenac sodium and paracetamol for analgesia in colonic anastomosis on rats. METHODS:Wistar-Hannover rats were randomly allocated to four groups: Group 1, sham-operated group; Group 2, control group; Group 3, diclofenac sodium group; Group 4, paracetamol group. After laparotomy, the left colon was transected and a single-layer anastomosis was made with 5/0 vicryl in Groups 2, 3, and 4. Only laparotomy was performed in Group 1. After anastomosis, we administered saline to Group 2, diclofenac sodium to Group 3, and paracetamol to Group 4 for 7 days. Then, all animals were decapitated. The anastomotic region was resected, and bursting pressure was measured. Then, the specimen was sent to the laboratory for histological examination and hydroxyproline analysis. RESULTS:Bursting pressure and hydroxyproline level were significantly higher in the paracetamol group (p<0.05). When we looked at the fibrosis levels of these groups, it was also higher in paracetamol group. CONCLUSION:Bursting pressure, hydroxyproline levels, and fibrosis levels indicate that the perioperative use of paracetamol for analgesia when undergoing colonic anastomosis is safer than diclofenac sodium.
journal_name
Asian J Surgjournal_title
Asian journal of surgeryauthors
Gulcicek OB,Solmaz A,Yigitbas H,Ercetin C,Yavuz E,Ozdogan K,Biricik A,Akkalp AK,Uzun H,Kutnu M,Celebi F,Celik Adoi
10.1016/j.asjsur.2017.01.002subject
Has Abstractpub_date
2018-05-01 00:00:00pages
264-269issue
3eissn
1015-9584issn
0219-3108pii
S1015-9584(16)30403-1journal_volume
41pub_type
杂志文章abstract:BACKGROUND:Although the incidence of complications of otitis media that require surgical interventions has decreased substantially over the past few years, it is a prevailing condition for which clinicians should remain vigilant. METHODS:We conducted a 3-year review [June 1998 to June 2001] in our hospital of surgical...
journal_title:Asian journal of surgery
pub_type: 杂志文章
doi:10.1016/S1015-9584(09)60168-8
更新日期:2002-04-01 00:00:00
abstract:BACKGROUND:Massive hemorrhage and the need for blood transfusion carry a high rate of morbidity and mortality after hepatectomy. The aim of this study was to evaluate the safety and potential benefit of infrahepatic inferior vena cava (IVC) clamping in hepatectomy for tumors involving hepatocaval confluence. METHODS:W...
journal_title:Asian journal of surgery
pub_type: 杂志文章
doi:10.1016/j.asjsur.2013.01.002
更新日期:2013-07-01 00:00:00
abstract:OBJECTIVE:Vesicovaginal fistula is mostly iatrogenic in origin and causes devastating medical, social, psychogenic and hygienic consequences. The aetiology has changed since the nineteenth century, becoming more associated with hysterectomy rather than other obstetric procedures, which were common in the past. We studi...
journal_title:Asian journal of surgery
pub_type: 杂志文章
doi:10.1016/S1015-9584(08)60037-8
更新日期:2007-10-01 00:00:00
abstract:OBJECTIVE:To report our experience of intracardiac surgery with an inverted J-shaped partial sternotomy (IJPS) and describe the technical details of this approach. METHODS:From January to December 2002, 31 patients underwent intracardiac operations using the IJPS instead of a standard conventional full-length median s...
journal_title:Asian journal of surgery
pub_type: 杂志文章
doi:10.1016/S1015-9584(09)60347-X
更新日期:2005-07-01 00:00:00
abstract:OBJECTIVE:Bladder catheterisation is a routine part of major abdominal surgery. Transurethral catheterisation is the most common method of bladder drainage but is also notorious for its discomfort and increased risk of urinary tract infection. The present study aimed to establish patient satisfaction with transurethral...
journal_title:Asian journal of surgery
pub_type: 杂志文章
doi:10.1016/S1015-9584(10)60006-1
更新日期:2010-01-01 00:00:00
abstract:OBJECTIVE:This study investigated the effectiveness of unilateral nephrectomy in the treatment of renal hypertension in adults with an atrophic kidney, and set out to establish whether this is an appropriate mode of treatment for renal hypertension not otherwise controlled by antihypertensive drugs or other surgical pr...
journal_title:Asian journal of surgery
pub_type: 杂志文章
doi:10.1016/S1015-9584(08)60083-4
更新日期:2008-10-01 00:00:00
abstract:OBJECTIVE:To determine the efficacy of intracorpus spongiosum anaesthesia during minor procedures on the glans and anterior urethra in the outpatient clinic. METHODS:Sixty-nine consecutive male patients underwent various procedures on the glans penis or anterior urethra under intracorpus spongiosum anaesthesia, which ...
journal_title:Asian journal of surgery
pub_type: 杂志文章
doi:10.1016/s1015-9584(09)60361-4
更新日期:2005-10-01 00:00:00
abstract:OBJECTIVE:To determine whether or not multimodality monitoring technique would result in a better outcome score than single modality monitoring in severely head injured patients. METHODS:This was a prospective randomized study that included all adults with traumatic severe head injury who had a Glasgow Coma Score < 9 ...
journal_title:Asian journal of surgery
pub_type: 杂志文章,随机对照试验
doi:10.1016/S1015-9584(08)60023-8
更新日期:2007-07-01 00:00:00
abstract:BACKGROUND:changes may occur in tumor phenotype and receptor status during the progression of breast cancer. Discordance between primary and metastases has implications for further treatment and prognosis. METHODS:185 patients confirmed breast cancer metastasis were retrospectively analyzed during 1999-2019. All the p...
journal_title:Asian journal of surgery
pub_type: 杂志文章
doi:10.1016/j.asjsur.2020.05.032
更新日期:2021-01-01 00:00:00
abstract:OBJECTIVE:To evaluate the efficacy of three-dimensional (3D) laparoscopy in urological procedures in a cohort study compared to two-dimensional (2D) laparoscopy. METHODS:From October 2016 to August 2017, 100 patients underwent various urological procedures with 3D laparoscopy performed by a single experienced surgeon ...
journal_title:Asian journal of surgery
pub_type: 杂志文章
doi:10.1016/j.asjsur.2018.04.012
更新日期:2019-01-01 00:00:00
abstract:BACKGROUND/OBJECTIVE:The concept of salvage pulmonary resection after definitive chemoradiotherapy (dCRT) is not yet commonly accepted in lung cancer treatment. We report our experience of eight patients in whom we performed salvage pulmonary resection for residual disease or isolated locoregional recurrence detected a...
journal_title:Asian journal of surgery
pub_type: 杂志文章
doi:10.1016/j.asjsur.2015.05.006
更新日期:2017-04-01 00:00:00
abstract:OBJECTIVE:To review retrospectively our clinical experience with surgical treatment and follow-up of pituitary adrenocorticotropic hormone (ACTH) microadenomas at Rui Jin Hospital of Shanghai Second Medical University. METHODS:Eighty-seven patients with ACTH microadenomas underwent surgery via the transsphenoidal appr...
journal_title:Asian journal of surgery
pub_type: 杂志文章
doi:10.1016/S1015-9584(09)60210-4
更新日期:2003-01-01 00:00:00
abstract::Fulminant hepatic failure can only be treated successfully by liver transplantation, which, however, is not always available. To "bridge" the patient with fulminant hepatic failure until a liver graft is available, various forms of liver support devices had been designed but they were not uniformly successful. To prov...
journal_title:Asian journal of surgery
pub_type: 杂志文章
doi:
更新日期:2002-01-01 00:00:00
abstract:BACKGROUND:Hemorrhoidectomy is commonly associated with postoperative pain. Calcium channel blockers are known to cause relaxation of gastrointestinal smooth muscle and oral diltiazem has also been shown to reduce the resting anal pressure. OBJECTIVE:We attempted to analyze efficacy and side effects of topical diltiaz...
journal_title:Asian journal of surgery
pub_type: 杂志文章,meta分析
doi:10.1016/j.asjsur.2017.06.002
更新日期:2018-09-01 00:00:00
abstract::Surgical smoke is the gaseous by-product formed during surgical procedures. Most surgeons, operating theatre staff and administrators are unaware of its potential health risks. Surgical smoke is produced by various surgical instruments including those used in electrocautery, lasers, ultrasonic scalpels, high speed dri...
journal_title:Asian journal of surgery
pub_type: 杂志文章
doi:10.1016/S1015-9584(09)60403-6
更新日期:2009-10-01 00:00:00
abstract:BACKGROUND:Preoperative differentiation of follicular thyroid carcinoma (FTC) from follicular adenoma (FA) remains an unsolved puzzle. Patients sometimes undergo unnecessary lobectomy for histology confirmation inevitably. OBJECTIVE:In this retrospective study, we propose new gray-scale ultrasonographic (US) features ...
journal_title:Asian journal of surgery
pub_type: 杂志文章
doi:10.1016/j.asjsur.2019.04.016
更新日期:2020-01-01 00:00:00
abstract::Over the last three decades, a series of clinical trials have led to the use of adjuvant pelvic radiotherapy and chemotherapy in high-risk (T3-4 or N1) rectal cancer. There is a need to improve patient selection in order to identify the group most at risk for recurrent disease. The toxicity of adjuvant therapy should ...
journal_title:Asian journal of surgery
pub_type: 杂志文章,评审
doi:10.1016/S1015-9584(09)60331-6
更新日期:2004-04-01 00:00:00
abstract:BACKGROUND:Little is known about the preoperative predictive factors that could identify subsets of favorable patients who can be possibly cured with robot-assisted radical prostatectomy (RARP) alone in locally advanced prostate cancer (LAPCa). Our study was designed to identify clinical predictors of pathologic organ-...
journal_title:Asian journal of surgery
pub_type: 杂志文章
doi:10.1016/j.asjsur.2017.10.005
更新日期:2019-01-01 00:00:00
abstract:PURPOSE:To evaluate the rate of surgical complications during the change from subtotal resection to hemithyroidectomy or thyroidectomy over a period of 17 years. METHODS:All operations for benign goiter at our hospital were analyzed for the periods 1996-2002 (Group 1) and 2003-2012 (Group 2). The groups were compared ...
journal_title:Asian journal of surgery
pub_type: 杂志文章
doi:10.1016/j.asjsur.2016.07.015
更新日期:2018-01-01 00:00:00
abstract:BACKGROUND:We previously reported our initial experience with laparoendoscopic single-site (LESS) retroperitoneal partial adrenalectomy using a custom-made single-port device and conventional straight laparoscopic instruments. METHODS:Between December 2010 and February 2012, LESS retroperitoneal partial adrenalectomie...
journal_title:Asian journal of surgery
pub_type: 杂志文章
doi:10.1016/j.asjsur.2014.01.014
更新日期:2015-01-01 00:00:00
abstract::Massive defects of the upper aerodigestive tract present a reconstructive challenge. We report a case in which a large defect of the naso-oropharyngeal and oesophagus was reconstructed with a combination of a gastric pull-up and a pectoralis major muscle flap. Postoperative function was good and survival was in excess...
journal_title:Asian journal of surgery
pub_type: 杂志文章
doi:10.1016/S1015-9584(09)60203-7
更新日期:2002-10-01 00:00:00
abstract::Necrotizing fasciitis is a potentially life threatening, rapidly spreading polymicrobial infection rarely seen in the head and neck region. We present our experience of managing five patients with necrotizing fasciitis of head and neck at the Aga Khan University Hospital, Karachi, Pakistan. One patient had necrotizing...
journal_title:Asian journal of surgery
pub_type: 杂志文章
doi:
更新日期:2002-01-01 00:00:00
abstract:OBJECTIVE:We tracked various proficiency indicators for the learning curve as a single Taiwanese surgeon became familiar with robotic-assisted laparoscopic radical prostatectomy surgeries by performing 60 initial procedures. METHODS:Between December 2005 and December 2007, 60 consecutive patients were classified into ...
journal_title:Asian journal of surgery
pub_type: 杂志文章
doi:10.1016/S1015-9584(11)60023-7
更新日期:2011-04-01 00:00:00
abstract:OBJECTIVE:Considerable controversy exists regarding the surgical indications for a concealed penis. We herein describe a modified technique for correction of a concealed penis. The superfluous inner plate is resected to accelerate the disappearance of the postoperative lymphedema, and the skin between the penis and scr...
journal_title:Asian journal of surgery
pub_type: 杂志文章
doi:10.1016/j.asjsur.2018.06.007
更新日期:2019-01-01 00:00:00
abstract:BACKGROUND/OBJECTIVE:The neutrophil-to-lymphocyte ratio (NLR) is a simple index that represents systemic inflammatory change. The number of platelets is also known to reflect both post-transplant graft regeneration and dysfunction. Thus, we aimed to investigate the usefulness of NLR and platelet number in predicting th...
journal_title:Asian journal of surgery
pub_type: 杂志文章
doi:10.1016/j.asjsur.2017.02.004
更新日期:2018-07-01 00:00:00
abstract:BACKGROUND/OBJECTIVE:A preoperative reliable classification system between clinical and computed tomography (CT) findings to better plan surgery in acute complicated diverticulitis (ACD) is lacking. We studied the inter-observer agreement of CT scan data and their concordance with the preoperative clinical findings and...
journal_title:Asian journal of surgery
pub_type: 杂志文章
doi:10.1016/j.asjsur.2019.07.016
更新日期:2020-03-01 00:00:00
abstract::Meckel diverticulum is the most common congenital anomaly of the small intestine, occurring in about 2%-4% of the population. Meckel diverticulum results from incomplete closure of the omphalomesenteric duct. The presentation of symptomatic Meckel diverticulum includes gastrointestinal hemorrhage, intestinal obstructi...
journal_title:Asian journal of surgery
pub_type: 杂志文章
doi:10.1016/j.asjsur.2012.04.018
更新日期:2012-10-01 00:00:00
abstract:BACKGROUND:Preoperative hypoalbuminemia is a well-known risk factor for anastomotic leakage after colorectal surgery, but the association between perioperative albumin level and anastomotic leakage has not been fully investigated in curative colorectal cancer (CRC) patients. METHODS:In total, 200 CRC patients (Stage I...
journal_title:Asian journal of surgery
pub_type: 杂志文章
doi:10.1016/j.asjsur.2016.07.009
更新日期:2018-01-01 00:00:00
abstract:OBJECTIVE:In this study, the perioperative outcomes of video-assisted thoracoscopic surgery (VATS) and robot-assisted thoracoscopic surgery (RATS) were compared in patients with clinical stage I and stage II thymoma. METHODS:The outcomes of 24 patients (10 males and 14 females; mean age: 42.5 years; range: 18-65 years...
journal_title:Asian journal of surgery
pub_type: 杂志文章
doi:10.1016/j.asjsur.2019.04.005
更新日期:2020-01-01 00:00:00
abstract:BACKGROUND:Preservation of the external branch of the superior laryngeal nerve (EBSLN) during thyroidectomy is important because its injury may lead to frequent occurrence of vocal fatigue and the inability to perform superenergetic phonation. Most studies on the anatomy of EBSLN have been performed in Western countrie...
journal_title:Asian journal of surgery
pub_type: 杂志文章
doi:10.1016/j.asjsur.2012.08.003
更新日期:2013-01-01 00:00:00