Abstract：
BACKGROUND:changes may occur in tumor phenotype and receptor status during the progression of breast cancer. Discordance between primary and metastases has implications for further treatment and prognosis. METHODS:185 patients confirmed breast cancer metastasis were retrospectively analyzed during 1999-2019. All the pathological assessments of receptors and phenotypes of both primaries and metastases were recorded. RESULTS:rates of receptor discordance were 18.65%, 30.57%, and 16.06% for ER, PR, and HER2, respectively and 31.62% for phenotype change. Patients with ER discordance experienced a worse OS and PMS, and those with ER loss had worse PMS compared with ER positive concordance. Patients with PR discordance experienced poorer OS and loss of PR positivity also had decreased OS and PMS when comparing with PR positive concordance. There was also significantly poorer PMS of hormon receptor (HR) discordance than HR positive concordance. In phenotype change, the luminal A type concordance group showed better PMS result. CONCLUSIONS:this study demonstrated that discordance in subtype and receptor status between primary and metastatic lesions ultimately affects the survival and has a potential impact on treatment options.
journal_name
Asian J Surgjournal_title
Asian journal of surgeryauthors
Kao JY,Tsai JH,Wu TY,Wang CK,Kuo YLdoi
10.1016/j.asjsur.2020.05.032subject
Has Abstractpub_date
2021-01-01 00:00:00pages
192-198issue
1eissn
1015-9584issn
0219-3108pii
S1015-9584(20)30181-0journal_volume
44pub_type
杂志文章abstract：OBJECTIVE:To determine the 5-year survival rate and prognostic factors for survival in patients with colorectal cancer treated at the Surgical Unit, Hospital Universiti Sains Malaysia (HUSM), Kelantan, Malaysia. METHODS:We retrospectively reviewed the records of 115 patients treated in HUSM from 1996 to 2005. Data of ...
journal_title：Asian journal of surgery
pub_type： 杂志文章
doi：10.1016/S1015-9584(10)60022-X
更新日期：2010-07-01 00:00:00
abstract：:Necrotizing fasciitis is a potentially life threatening, rapidly spreading polymicrobial infection rarely seen in the head and neck region. We present our experience of managing five patients with necrotizing fasciitis of head and neck at the Aga Khan University Hospital, Karachi, Pakistan. One patient had necrotizing...
journal_title：Asian journal of surgery
pub_type： 杂志文章
doi：
更新日期：2002-01-01 00:00:00
abstract：BACKGROUND:Many surgical techniques have been developed to treat inguinal hernia. In recent years, the laparoscopic transabdominal preperitoneal (TAPP) approach has been widely performed to repair inguinal hernia. Giant inguinal hernia (GIH) is an extremely rare disease that is a challenge for general surgeons. GIH app...
journal_title：Asian journal of surgery
pub_type： 杂志文章
doi：10.1016/j.asjsur.2017.12.004
更新日期：2019-01-01 00:00:00
abstract：:We report a patient with familial hypocalciuric hypercalcemia (FHH) associated with primary hyperparathyroidism (PHPT) and incidental papillary thyroid carcinoma. The patient showed hypercalcemia, high parathyroid hormone (PTH) levels and low urinary calcium excretion. A computed tomography (CT) scan revealed an enlar...
journal_title：Asian journal of surgery
pub_type： 杂志文章
doi：10.1016/S1015-9584(09)60022-1
更新日期：2009-04-01 00:00:00
abstract：BACKGROUND:To elucidate the clinicopathological features of multiply recurrent retroperitoneal liposarcoma referred to a tertiary center. METHODS:We retrospectively analyzed the clinical data of 40 patients with pathologically proven primary retroperitoneal liposarcoma treated between January 2015 and June 2019. RESU...
journal_title：Asian journal of surgery
pub_type： 杂志文章
doi：10.1016/j.asjsur.2020.10.015
更新日期：2021-01-01 00:00:00
abstract：OBJECTIVE:To evaluate the efficacy of three-dimensional (3D) laparoscopy in urological procedures in a cohort study compared to two-dimensional (2D) laparoscopy. METHODS:From October 2016 to August 2017, 100 patients underwent various urological procedures with 3D laparoscopy performed by a single experienced surgeon ...
journal_title：Asian journal of surgery
pub_type： 杂志文章
doi：10.1016/j.asjsur.2018.04.012
更新日期：2019-01-01 00:00:00
abstract：BACKGROUND:Preservation of the external branch of the superior laryngeal nerve (EBSLN) during thyroidectomy is important because its injury may lead to frequent occurrence of vocal fatigue and the inability to perform superenergetic phonation. Most studies on the anatomy of EBSLN have been performed in Western countrie...
journal_title：Asian journal of surgery
pub_type： 杂志文章
doi：10.1016/j.asjsur.2012.08.003
更新日期：2013-01-01 00:00:00
abstract：BACKGROUND:This study investigated the optimal timing of analgesic transversus abdominis plane (TAP) block in the operating room for better recovery quality using the Korean version of the Quality of Recovery-40 (QoR-40K) questionnaire in patients who had undergone open inguinal herniorrhaphy. METHODS:This single-cent...
journal_title：Asian journal of surgery
pub_type： 杂志文章
doi：10.1016/j.asjsur.2020.06.001
更新日期：2021-01-01 00:00:00
abstract：OBJECTIVE:Eighty to ninety percent of Hirschsprung's disease (HD) patients present in newborns. However, the diagnosis of HD in the neonatal period remains difficult. Our present study aims to propose a diagnostic scoring system and hope this will increase early diagnosis of HD and avoid unnecessary rectal biopsy. MET...
journal_title：Asian journal of surgery
pub_type： 杂志文章
doi：10.1016/S1015-9584(09)60082-8
更新日期：2006-07-01 00:00:00
abstract：:Magnetic resonance cholangiography (MRC) is a non-invasive imaging modality that has become widely available. In the short time since its introduction, MRC has been shown to possess excellent accuracy for the diagnosis of various biliary pathologies, including choledocholithiasis. Investigations of the clinical applic...
journal_title：Asian journal of surgery
pub_type： 杂志文章,评审
doi：10.1016/S1015-9584(09)60321-3
更新日期：2004-04-01 00:00:00
abstract：:Retroperitoneal cysts are rare, usually asymptomatic, lesions. We present the case of a 42-year-old woman with an asymptomatic abdominal mass. The mass excised at our district hospital was found in the retroperitoneum. Histologically, the cyst was lined with benign Mullerian-type epithelium. The classification, aetiol...
journal_title：Asian journal of surgery
pub_type： 杂志文章
doi：10.1016/S1015-9584(09)60062-2
更新日期：2004-10-01 00:00:00
abstract：:Meckel diverticulum is the most common congenital anomaly of the small intestine, occurring in about 2%-4% of the population. Meckel diverticulum results from incomplete closure of the omphalomesenteric duct. The presentation of symptomatic Meckel diverticulum includes gastrointestinal hemorrhage, intestinal obstructi...
journal_title：Asian journal of surgery
pub_type： 杂志文章
doi：10.1016/j.asjsur.2012.04.018
更新日期：2012-10-01 00:00:00
abstract：BACKGROUND:Massive hemorrhage and the need for blood transfusion carry a high rate of morbidity and mortality after hepatectomy. The aim of this study was to evaluate the safety and potential benefit of infrahepatic inferior vena cava (IVC) clamping in hepatectomy for tumors involving hepatocaval confluence. METHODS:W...
journal_title：Asian journal of surgery
pub_type： 杂志文章
doi：10.1016/j.asjsur.2013.01.002
更新日期：2013-07-01 00:00:00
abstract：BACKGROUND/OBJECTIVE:The neutrophil-to-lymphocyte ratio (NLR) is a simple index that represents systemic inflammatory change. The number of platelets is also known to reflect both post-transplant graft regeneration and dysfunction. Thus, we aimed to investigate the usefulness of NLR and platelet number in predicting th...
journal_title：Asian journal of surgery
pub_type： 杂志文章
doi：10.1016/j.asjsur.2017.02.004
更新日期：2018-07-01 00:00:00
abstract：:Greater experience and improved outcomes in liver transplantation have necessarily led to longer waiting lists against a constantly limited donor pool. Split liver transplantation has been conceived as a means to increase the supply of liver grafts. The bipartition of a whole liver provides grafts for two recipients i...
journal_title：Asian journal of surgery
pub_type： 杂志文章
doi：10.1016/S1015-9584(09)60193-7
更新日期：2002-10-01 00:00:00
abstract：OBJECTIVE:The frequent complications of thyroid surgery are mostly related to the anatomy of the region. This stimulated us to look for a starting point that makes exploration of the region easier and consequently reduces complications. We aimed to explore and define the anatomy of the cricothyroid [CT] region from cad...
journal_title：Asian journal of surgery
pub_type： 临床试验,杂志文章
doi：10.1016/S1015-9584(09)60180-9
更新日期：2002-07-01 00:00:00
abstract：BACKGROUND/OBJECTIVE:Patients on hemodialysis (HD) who undergo abdominal surgery for gastrointestinal disease are at increased risk of postoperative complications. In this study, we retrospectively investigated the predictors of postoperative complications among such patients. METHODS:The study group comprised 36 HD p...
journal_title：Asian journal of surgery
pub_type： 杂志文章
doi：10.1016/j.asjsur.2015.03.013
更新日期：2016-10-01 00:00:00
abstract：OBJECTIVE:To assess ultrasonographically (US) guided needle aspiration of breast abscesses as an alternative to surgical incision and drainage. METHODS:In our prospective study, 30 patients with 31 breast abscesses (one patient had bilateral breast abscess) underwent percutaneous breast abscess drainage under US guida...
journal_title：Asian journal of surgery
pub_type： 杂志文章
doi：10.1016/S1015-9584(09)60126-3
更新日期：2007-01-01 00:00:00
abstract：:Spontaneous intramural duodenal haematoma (IDH) is an uncommon pathology and it is usually related to anticoagulant therapy. Other causes include various pancreatic diseases, connective tissue disease, peptic ulcer disease and pancreaticoduodenal aneurysm. IDH of pancreatic origin has been infrequently reported. The d...
journal_title：Asian journal of surgery
pub_type： 杂志文章,评审
doi：10.1016/S1015-9584(08)60063-9
更新日期：2008-04-01 00:00:00
abstract：BACKGROUND:5-Aminolevulinic Acid (5-ALA) induced fluorescence is useful in guiding glioma resection. The extent of 5-ALA accumulation is beyond gadolinium contrast enhancement.1,2 Supratotal resection may be achieved, potentially granting patients with better survival. We present our experience on 5-ALA guided glioma r...
journal_title：Asian journal of surgery
pub_type： 杂志文章
doi：10.1016/j.asjsur.2017.06.004
更新日期：2018-09-01 00:00:00
abstract：BACKGROUND:Hemorrhoidectomy is commonly associated with postoperative pain. Calcium channel blockers are known to cause relaxation of gastrointestinal smooth muscle and oral diltiazem has also been shown to reduce the resting anal pressure. OBJECTIVE:We attempted to analyze efficacy and side effects of topical diltiaz...
journal_title：Asian journal of surgery
pub_type： 杂志文章,meta分析
doi：10.1016/j.asjsur.2017.06.002
更新日期：2018-09-01 00:00:00
abstract：OBJECTIVE:Vesicovaginal fistula is mostly iatrogenic in origin and causes devastating medical, social, psychogenic and hygienic consequences. The aetiology has changed since the nineteenth century, becoming more associated with hysterectomy rather than other obstetric procedures, which were common in the past. We studi...
journal_title：Asian journal of surgery
pub_type： 杂志文章
doi：10.1016/S1015-9584(08)60037-8
更新日期：2007-10-01 00:00:00
abstract：:Bilateral cortisol-secreting adenomas are a rare cause of Cushing's syndrome. We report a case of a 35-year-old woman who presented with ACTH-independent Cushing's syndrome and bilateral adrenal adenomas. Adrenal venous sampling confirmed both adenomas to be hyper-secreting cortisol. She underwent bilateral laparoscop...
journal_title：Asian journal of surgery
pub_type： 杂志文章
doi：10.1016/S1015-9584(09)60152-4
更新日期：2007-04-01 00:00:00
abstract：BACKGROUND:We previously reported our initial experience with laparoendoscopic single-site (LESS) retroperitoneal partial adrenalectomy using a custom-made single-port device and conventional straight laparoscopic instruments. METHODS:Between December 2010 and February 2012, LESS retroperitoneal partial adrenalectomie...
journal_title：Asian journal of surgery
pub_type： 杂志文章
doi：10.1016/j.asjsur.2014.01.014
更新日期：2015-01-01 00:00:00
abstract：BACKGROUND:To review currently available evidence on the use of adjuvant therapy to reduce the formation of postoperative intra-abdominal adhesions. METHODS:A search on Pubmed and the Cochrane library was undertaken using the keywords "abdominal", "adhesion", "postoperative", "prevention" and "reduction". Only randomi...
journal_title：Asian journal of surgery
pub_type： 杂志文章,评审
doi：10.1016/S1015-9584(09)60392-4
更新日期：2009-07-01 00:00:00
abstract：:We present the case of a 32-year-old woman who, 10 months after abdominoperineal resection and total mesorectal excision for a locally advanced mucinous adenocarcinoma of the rectum, presented with local recurrence and metastases to the breast, spine, the left eye and orbit. Following surgery, due to the patient's per...
journal_title：Asian journal of surgery
pub_type： 杂志文章
doi：10.1016/S1015-9584(09)60115-9
更新日期：2006-04-01 00:00:00
abstract：:Surgical smoke is the gaseous by-product formed during surgical procedures. Most surgeons, operating theatre staff and administrators are unaware of its potential health risks. Surgical smoke is produced by various surgical instruments including those used in electrocautery, lasers, ultrasonic scalpels, high speed dri...
journal_title：Asian journal of surgery
pub_type： 杂志文章
doi：10.1016/S1015-9584(09)60403-6
更新日期：2009-10-01 00:00:00
abstract：BACKGROUND:Esophageal foreign bodies (EFBs) are a relatively common clinical problem in pediatric patients. The majority of EFBs pass harmlessly through the gastrointestinal tract; however, some EFBs can cause significant morbidities. This study was conducted to review our experience in managing esophageal foreign bodi...
journal_title：Asian journal of surgery
pub_type： 杂志文章
doi：10.1016/j.asjsur.2015.12.008
更新日期：2017-09-01 00:00:00
abstract：:This study retrospectively evaluated bronchoscopic and surgical treatments for patients with central airway stenosis due to tracheal tumours. Seven patients treated by resection and reconstruction of the trachea for tracheal tumours between 1994 and 2008 were retrospectively reviewed. The most common histological find...
journal_title：Asian journal of surgery
pub_type： 杂志文章
doi：10.1016/S1015-9584(11)60010-9
更新日期：2010-10-01 00:00:00
abstract：:We report two cases of prenatally diagnosed cystic neuroblastoma (PDCN). In the first case, prenatal ultrasonography (US) at 33 weeks' gestation showed a 30 x 20 mm cyst at the upper pole of the right kidney. The size and content of the mass demonstrated no change during pregnancy. Postnatal US showed no change in the...
journal_title：Asian journal of surgery
pub_type： 杂志文章
doi：10.1016/s1015-9584(09)60309-2
更新日期：2003-10-01 00:00:00
