Abstract:
AIM:The bone implant contact (BIC) has traditionally been evaluated with histological methods. Thereupon, strong correlations of two-dimensional (2D) BIC have been detected between μCT and destructive histology. However, due to the high intra-sample variability in BIC values, one histological slice is not sufficient to represent 3D BIC. Therefore, our aim has been to correlate the averaged values of 3-4 histological sections to 3D μCT. MATERIAL AND METHODS:Fifty-four implants inserted into the maxilla of 14 minipigs were evaluated. Two different time points were selected to assess the 3D BIC (distance to implant: 2-5 voxels), an inner ring (6-30 voxels) and an outer ring (55-100 voxels) using μCT (voxel size: 10 μm) and to correlate the values to histomorphometry. RESULTS:Strong correlations (p < 0.0001; 28 days, 56 days, total) were seen between μCT and histomorphometry concerning BIC (r = 0.84, r = 0.85, r = 0.83), the inner ring (r = 0.87, r = 0.87, r = 0.88) and the outer ring (r = 0.85, r = 0.85, r = 0.88). Closer to the implant, μCT values were higher compared with histomorphometry. CONCLUSION:Although 3-4 histological slices per implant seem to predict the 3D BIC, μCT might be advantageous because of its non-destructive 3D character. The healing time may not impact on the comparability.
journal_name
J Clin Periodontoljournal_title
Journal of clinical periodontologyauthors
Bissinger O,Probst FA,Wolff KD,Jeschke A,Weitz J,Deppe H,Kolk Adoi
10.1111/jcpe.12693subject
Has Abstractpub_date
2017-04-01 00:00:00pages
418-427issue
4eissn
0303-6979issn
1600-051Xjournal_volume
44pub_type
杂志文章abstract:OBJECTIVE:The aim of this study was to evaluate long-term (24 weeks) alveolar bone maturation following surgical application of recombinant human growth/differentiation factor-5 (rhGDF-5) in an injectable poly-lactide-co-glycolide-acid (PLGA) composite carrier using an established periodontal defect model. METHODS:Rou...
journal_title:Journal of clinical periodontology
pub_type: 杂志文章
doi:10.1111/j.1600-051X.2012.01868.x
更新日期:2012-06-01 00:00:00
abstract::This investigation compares the Periotron 6000, Periotron 600, and ninhydrin area systems for quantifying gingival fluid. All systems have highly significant (p less than 0.001) linear relationships between measurements and fluid volumes. Additional curvilinear components have virtually no clinically significant impli...
journal_title:Journal of clinical periodontology
pub_type: 杂志文章
doi:10.1111/j.1600-051x.1984.tb01313.x
更新日期:1984-11-01 00:00:00
abstract:OBJECTIVES:Safety and efficacy of glycine powder air-polishing (GPAP) in removing subgingival biofilm have been previously demonstrated. The hypothesis that GPAP results in less gingival erosion than sodium bicarbonate air-polishing (SBAP) or hand-instrumentation was assessed. MATERIAL AND METHODS:In each of 10 patien...
journal_title:Journal of clinical periodontology
pub_type: 杂志文章,随机对照试验
doi:10.1111/j.1600-051X.2007.01195.x
更新日期:2008-04-01 00:00:00
abstract:AIM:For periodontitis patients, regular supportive periodontal therapy (SPT) decreases risks of tooth loss, with savings for tooth replacement possibly compensating SPT-costs. We aimed to assess the cost-effectiveness of regular versus irregular SPT, and to compare both strategies with immediate tooth removal. METHODS...
journal_title:Journal of clinical periodontology
pub_type: 杂志文章
doi:10.1111/jcpe.12595
更新日期:2016-11-01 00:00:00
abstract:AIM:To compare immediate surgery to scaling and root planing (SRP) in the treatment of advanced periodontitis focusing on the prevalence of residual pockets after treatment and cost-effectiveness (1); to elucidate the adjunctive effects of azithromycin in a second-treatment phase (2) up to 36 months. MATERIALS AND MET...
journal_title:Journal of clinical periodontology
pub_type: 杂志文章
doi:10.1111/jcpe.12434
更新日期:2015-08-01 00:00:00
abstract:AIM:The aim of this study was to establish the prevalence of dentine hypersensitivity in a cross-sectional study of patients visiting general dental practitioners in the South West region of the UK over a period of 1 calendar month. METHOD:Twelve dental practitioners examined 3593 patients over a period of 1 calendar ...
journal_title:Journal of clinical periodontology
pub_type: 杂志文章
doi:10.1034/j.1600-051x.2000.027011860.x
更新日期:2000-11-01 00:00:00
abstract::The purpose of the study was to examine the association between alignment conditions of anterior teeth and dental health in 15-year-old adolescents. The study group consisted of 74 females and 70 males with 6 anterior teeth in both jaws. The following parameters were assessed: plaque index (P1I), gingival index (GI), ...
journal_title:Journal of clinical periodontology
pub_type: 杂志文章
doi:10.1111/j.1600-051x.1985.tb02297.x
更新日期:1985-04-01 00:00:00
abstract::There has been a vigorous search for many years for chemical agents that could supplement or even supplant patient-dependent mechanical plaque control and thus reduce or prevent oral disease. 5 categories of agents or approaches have been considered: (1) broad spectrum antiseptics, (2) antibiotics aimed at specific ba...
journal_title:Journal of clinical periodontology
pub_type: 杂志文章,评审
doi:10.1111/j.1600-051x.1988.tb01020.x
更新日期:1988-09-01 00:00:00
abstract::The purpose of this clinical trial was to compare the effectiveness and safety of a new dental flossing device (Quik Floss) to finger flossing in plaque removal, reduction of gingival inflammation and patient preference. 30 healthy, non-flossing adults with 20 natural teeth, a plaque index (PI) of at least 1.8 and a g...
journal_title:Journal of clinical periodontology
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1111/j.1600-051x.1996.tb00626.x
更新日期:1996-09-01 00:00:00
abstract:BACKGROUND:Subantimicrobial dose doxycycline (SDD--20 mg doxycycline twice daily) is indicated as an adjunctive treatment for periodontitis. Doxycycline downregulates the activity of matrix metalloproteinases (MMPs), key destructive enzymes in periodontal disease. Current understanding of periodontal pathogenesis sugge...
journal_title:Journal of clinical periodontology
pub_type: 杂志文章,评审
doi:10.1111/j.1600-051X.2004.00558.x
更新日期:2004-09-01 00:00:00
abstract::A trial was conducted to compare the effectiveness of povidone iodine and chlorhexidine gluconate with buffered peroxyborate in the treatment of acute ulcerative gingivitis. After 20 patients had entered the trial and 11 had required additional therapy with metronidazole to control their symptoms, the study was termin...
journal_title:Journal of clinical periodontology
pub_type: 临床试验,杂志文章
doi:10.1111/j.1600-051x.1978.tb01919.x
更新日期:1978-11-01 00:00:00
abstract:AIM:The primary aim of the study was to systematically map registration records on periodontal medicine in clinical trial registers. The secondary aim was to assess the evolution of periodontal medicine in clinical periodontal research as a whole. MATERIAL AND METHODS:We searched all registration records related to pe...
journal_title:Journal of clinical periodontology
pub_type: 杂志文章,评审
doi:10.1111/jcpe.12534
更新日期:2016-05-01 00:00:00
abstract:OBJECTIVES:The primary aetiologic factor of periodontal disease is the bacterial biofilm. Gram-positive and gram-negative bacteria possess a plethora of structural or secreted components that may cause direct destruction to periodontal tissues or stimulate host cells to activate a wide range of inflammatory responses. ...
journal_title:Journal of clinical periodontology
pub_type: 杂志文章,评审
doi:10.1111/j.1600-051X.2005.00821.x
更新日期:2005-01-01 00:00:00
abstract::The aim of the present study was to compare linear measurements of interproximal bone loss on digitized radiographic images after application of different filters to the gold standard of intrasurgical measurements. Immediately before surgery, 50 radiographs of 50 periodontally-diseased teeth exhibiting interproximal b...
journal_title:Journal of clinical periodontology
pub_type: 杂志文章
doi:10.1034/j.1600-051x.1999.260506.x
更新日期:1999-05-01 00:00:00
abstract:AIMS:The goal of this review is to identify the antimicrobial proteins in the oral fluids, saliva and gingival crevicular fluid and identify functional families and candidates for antibacterial treatment. RESULTS:Periodontal biofilms initiate a cascade of inflammatory and immune processes that lead to the destruction ...
journal_title:Journal of clinical periodontology
pub_type: 杂志文章,评审
doi:10.1111/j.1600-051X.2010.01664.x
更新日期:2011-03-01 00:00:00
abstract:OBJECTIVES:A relationship between poor oral health and coronary heart disease (CHD) and systemic inflammatory and haemostatic factors has been recently documented in an Italian population. The present study was performed to assess whether intensive dental care may produce a periodontal improvement along with a change i...
journal_title:Journal of clinical periodontology
pub_type: 杂志文章
doi:10.1111/j.1600-051X.2005.00641.x
更新日期:2005-02-01 00:00:00
abstract::Clinical healing following guided tissue regeneration (GTR) in deep intrabony pockets was compared to healing following gingival flap surgery alone (GFS). 15 patients received the GTR treatment including an expanded polytetrafluoroethylene membrane. 13 other patients received the control treatment GFS. A postsurgery p...
journal_title:Journal of clinical periodontology
pub_type: 临床试验,杂志文章
doi:10.1111/j.1600-051x.1996.tb01806.x
更新日期:1996-12-01 00:00:00
abstract::This Supplement provides clear evidence that essential oil (EO) mouthwashes can be a beneficial, safe component of daily oral health routines. However, despite the wealth of supporting evidence, several issues are worthy of discussion. Patient compliance is a clear issue with oral home-care routines, and the emphasis ...
journal_title:Journal of clinical periodontology
pub_type: 杂志文章
doi:10.1034/j.1600-051x.30.s5.8.x
更新日期:2003-01-01 00:00:00
abstract:AIM:The pathophysiology of periodontal diseases involves aspects of immunity and bone remodelling. Considering the role of the kinin B1 receptor (Bdkrb1) in inflammation and healing, the purpose of this study was to evaluate the contribution of Bdkrb1 to the pathogenesis of periodontitis. MATERIAL AND METHODS:We used ...
journal_title:Journal of clinical periodontology
pub_type: 杂志文章
doi:10.1111/jcpe.12097
更新日期:2013-07-01 00:00:00
abstract::An experimental study was designed to compare the claimed antibacterial effect of Betadine and Blend-a-med Fluid with the known plaque growth inhibiting effect of a 0.2% aqueous solution of chlorhexidine digluconate (Hibitane). Before the test perios for 5 days. During the following week they cleaned their teeth mecha...
journal_title:Journal of clinical periodontology
pub_type: 杂志文章
doi:10.1111/j.1600-051x.1976.tb00038.x
更新日期:1976-11-01 00:00:00
abstract:OBJECTIVES:The purpose of this investigation is to describe histologically the undisturbed healing of fresh extraction sockets when compared to immediate implant placement. METHODS:In eight beagle dogs, after extraction of the 3P3 and 4P4, implants were inserted into the distal sockets of the premolars, while the mesi...
journal_title:Journal of clinical periodontology
pub_type: 杂志文章
doi:10.1111/j.1600-051X.2011.01803.x
更新日期:2012-01-01 00:00:00
abstract:AIM:The aim of this report was to assess the strength and influence of periodontitis as a possible risk factor for pre-term birth (PTB) in a cohort of 81 primiparous Croatian mothers aged 18-39 years. METHODS:PTB cases (n = 17; mean age 25 +/- 2.9 years; age range 20-33 years) were defined as spontaneous delivery afte...
journal_title:Journal of clinical periodontology
pub_type: 杂志文章
doi:10.1111/j.1600-051X.2006.00977.x
更新日期:2006-10-01 00:00:00
abstract:OBJECTIVE:To determine the concentration of cathepsin K secreted into the crevicular fluid around dental implants and its correlation with clinical parameters of healthy implants and implants showing clinical signs of peri-implantitis. MATERIAL AND METHODS:Nineteen patients with 40 implants with and without peri-impla...
journal_title:Journal of clinical periodontology
pub_type: 杂志文章
doi:10.1111/j.1600-051X.2006.00904.x
更新日期:2006-04-01 00:00:00
abstract::In the present study, radiographs of a model simulating several degrees of alveolar bone height were taken at different vertical projection angles. Bone height was measured by three examiners utilizing a projection technique similar to that originally employed by Björn et al. (1966, 1969). Correlation coefficients of ...
journal_title:Journal of clinical periodontology
pub_type: 杂志文章
doi:10.1111/j.1600-051x.1981.tb00896.x
更新日期:1981-12-01 00:00:00
abstract:OBJECTIVES:The aim of the present study was to evaluate the impact of guided bone regeneration and defect dimension on wound healing at chemically modified titanium implant surfaces (modSLA). MATERIALS AND METHODS:ModSLA implants were placed at chronic-type lateral ridge defects of different heights (H1-H4: 2, 4, 6 an...
journal_title:Journal of clinical periodontology
pub_type: 杂志文章
doi:10.1111/j.1600-051X.2010.01551.x
更新日期:2010-05-01 00:00:00
abstract:OBJECTIVES:The aim of this multicenter trial was to compare the clinical and radiographical outcome of a ready-to-use Emdogain-gel (test) with the marketed Emdogain (control). METHODS:Subjects with bilateral infrabony defects > or =4 mm deep and > or =2 mm wide according to radiographs were selected. 88 subjects with ...
journal_title:Journal of clinical periodontology
pub_type: 临床试验,杂志文章,多中心研究,随机对照试验
doi:10.1034/j.1600-051x.2001.028010923.x
更新日期:2001-10-01 00:00:00
abstract:AIM:To analyse the evidence pertaining to post-extraction dimensional changes in the alveolar ridge after unassisted socket healing. MATERIALS AND METHODS:The protocol of this PRISMA-compliant systematic review (SRs) was registered in PROSPERO (CRD42020178857). A literature search to identify studies that fulfilled th...
journal_title:Journal of clinical periodontology
pub_type: 杂志文章,评审
doi:10.1111/jcpe.13390
更新日期:2021-01-01 00:00:00
abstract::Periodontitis is generally considered to be a consequence of an unfavourable host-parasite interaction in which bacteria are the determinants of disease. An intense search continues for the bacteria, specific or non-specific, that are responsible for periodontitis and various forms of the periodontal diseases have bee...
journal_title:Journal of clinical periodontology
pub_type: 杂志文章,评审
doi:10.1111/j.1600-051x.1995.tb00125.x
更新日期:1995-02-01 00:00:00
abstract::The purpose of this study was to see if the root surface topography of teeth, stored in saline and subsequently treated with citric acid, differred from the root surface topography of teeth that were treated immediately upon extraction, 12 freshly extracted adult human permanent teeth, with proximal surfaces free of c...
journal_title:Journal of clinical periodontology
pub_type: 杂志文章
doi:10.1111/j.1600-051x.1997.tb01841.x
更新日期:1997-04-01 00:00:00
abstract::The purpose of this investigation was to compare the levels of serum IgG2, the frequency of detection of Gm(23)-negative allotype and frequency of detection of FcgammaRIIa and FcgammaRIIIb receptor haplotypes in 32 refractory, 54 successfully treated and 27 periodontally healthy individuals. Refractory subjects showed...
journal_title:Journal of clinical periodontology
pub_type: 杂志文章
doi:10.1111/j.1600-051x.1998.tb02475.x
更新日期:1998-06-01 00:00:00