The relationship between risk factors and medication adherence among breast cancer survivors: What explanatory role might depression play?

Abstract:

OBJECTIVE:Despite the efficacy of clinical treatments (eg, adjuvant hormonal therapy) for breast cancer survivors (BCS), nonadherence rates remain high, increasing the risk of recurrence and mortality. The current study tested a theoretical model of medical nonadherence that proposes depression to be the most proximal predictor of medical nonadherence among BCS. METHODS:Breast cancer survivors were recruited from radiation clinics in Missouri. Survey data were collected 12 months after the end of primary treatment. The sample size included 133 BCS. RESULTS:Findings show substantial support for the model, demonstrating that depression mediated the relation between physical symptoms, cognitive symptoms, social support, and adherence to medication. This finding was replicated with a measure of mood disturbance. CONCLUSIONS:These findings support the prediction that medication nonadherence among BCS multiply determined process and have compelling implications for healthcare providers and interventions designed to increase medication adherence among BCS.

journal_name

Psychooncology

journal_title

Psycho-oncology

authors

Markovitz LC,Drysdale NJ,Bettencourt BA

doi

10.1002/pon.4362

subject

Has Abstract

pub_date

2017-12-01 00:00:00

pages

2294-2299

issue

12

eissn

1057-9249

issn

1099-1611

journal_volume

26

pub_type

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