Abstract:
OBJECTIVE:Despite the efficacy of clinical treatments (eg, adjuvant hormonal therapy) for breast cancer survivors (BCS), nonadherence rates remain high, increasing the risk of recurrence and mortality. The current study tested a theoretical model of medical nonadherence that proposes depression to be the most proximal predictor of medical nonadherence among BCS. METHODS:Breast cancer survivors were recruited from radiation clinics in Missouri. Survey data were collected 12 months after the end of primary treatment. The sample size included 133 BCS. RESULTS:Findings show substantial support for the model, demonstrating that depression mediated the relation between physical symptoms, cognitive symptoms, social support, and adherence to medication. This finding was replicated with a measure of mood disturbance. CONCLUSIONS:These findings support the prediction that medication nonadherence among BCS multiply determined process and have compelling implications for healthcare providers and interventions designed to increase medication adherence among BCS.
journal_name
Psychooncologyjournal_title
Psycho-oncologyauthors
Markovitz LC,Drysdale NJ,Bettencourt BAdoi
10.1002/pon.4362subject
Has Abstractpub_date
2017-12-01 00:00:00pages
2294-2299issue
12eissn
1057-9249issn
1099-1611journal_volume
26pub_type
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