Abstract:
:We present a case of cutaneous mucormycosis in a patient with several important risk factors precipitating disease, namely underlying acute myeloid leukaemia and poorly controlled secondary diabetes. Inoculation was most likely caused by repeated minor trauma (insulin injection) at the site of infection. Treatment consisted of surgical debridement and liposomal Amphotericin B (LAmB) during 71 days. Posaconazole had already been initiated prior to infection as primary antifungal prophylaxis but was discontinued during follow-up as susceptibility testing later revealed resistance to posaconazole. Additional treatment with caspofungin and G-CSF was associated because of poor initial result to treatment. Caspofungin was later continued as monotherapy when LAmB had to be interrupted because of renal toxicity. Treatment was completed after closure of the surgical site. The patient was successfully treated and remains infection free for one year after initial diagnosis.
journal_name
Acta Clin Belgjournal_title
Acta clinica Belgicaauthors
Delie A,Vlummens P,Creytens D,Steel Edoi
10.1080/17843286.2016.1266802subject
Has Abstractpub_date
2017-10-01 00:00:00pages
352-356issue
5eissn
1784-3286issn
2295-3337journal_volume
72pub_type
杂志文章,评审abstract::Over the past few years there have been enormous changes in the management of stroke patients. General practitioners, ambulance personnel/paramedics and the general public need to be well informed that stroke is a medical emergency. Prevention of secondary brain damage by normalising vital parameters and combating fev...
journal_title:Acta clinica Belgica
pub_type: 杂志文章,评审
doi:10.1080/17843286.1999.11754250
更新日期:1999-10-01 00:00:00
abstract::Background Trichinellosis is a parasitic infection caused by nematodes of the genus Trichinella, and its principal mode of transmission is the consumption of raw or undercooked contaminated meat. Cardiac involvement in trichinellosis is unusual, yet it represents the most frequent cause of death. Here, we report a cas...
journal_title:Acta clinica Belgica
pub_type: 杂志文章
doi:10.1080/17843286.2020.1790867
更新日期:2020-07-04 00:00:00
abstract::A multidisciplinary pulmonary rehabilitation program has become an important part of the treatment of chronic obstructive pulmonary disease. It can improve both exercise tolerance and health related quality of life in these patients. Exercise training has to be included for the program to be successful. The intensity ...
journal_title:Acta clinica Belgica
pub_type: 杂志文章,评审
doi:10.1179/acb.2010.071
更新日期:2010-09-01 00:00:00
abstract::Background/aim: To determine insulin sensitivity before chemotherapy and during febrile neutropenia in patients with acute leukemia and to assess its effect on the number of documented infections, the severity of infection and the outcome of the first hospitalization. To compare insulin sensitivity in the study group ...
journal_title:Acta clinica Belgica
pub_type: 杂志文章
doi:10.1080/17843286.2018.1534577
更新日期:2019-12-01 00:00:00
abstract:BACKGROUND:Multicentric Castleman's disease (MCD) is a rare, non-clonal lymphoproliferative disorder characterized by constitutional symptoms, anaemia and generalised lymphadenopathy. Its incidence among the HIV-positive population seems to have increased during the past decades. AIM:The present study intends to compa...
journal_title:Acta clinica Belgica
pub_type: 杂志文章,评审
doi:10.2143/ACB.66.1.2062510
更新日期:2011-01-01 00:00:00
abstract::Since the era of highly active antiretroviral therapy (HAART), HIV is considered a chronic disease. Adherence to HAART is crucial for effectiveness. Non-adherence negatively impacts patient outcome and the larger economy. However, data on adherence among the Belgian HIV cohort are scarce. Therefore, the purpose of thi...
journal_title:Acta clinica Belgica
pub_type: 杂志文章
doi:10.1179/0001551214Z.00000000035
更新日期:2014-04-01 00:00:00
abstract::We present a patient with therapy resistant multicentric reticulohistiocytosis (MRH). MRH is a rare granulomatous, multisystem disease characterised most frequently by disfiguring papulonodular skin lesions and sometimes a destructive polyarthritis, though any organ can be involved. Abnormal histiocytic reactions to a...
journal_title:Acta clinica Belgica
pub_type: 杂志文章
doi:10.2143/ACB.66.1.2062520
更新日期:2011-01-01 00:00:00
abstract::We report the case of a 60-year-old man who presented with sudden visual loss, a history of postprandial abdominal pain, malabsorption, and skin lesions typical of systemic Degos' disease. Despite anti-aggregants and prednisone the patient's status did not improve. On the basis of the hypothetical dysimmune origin of ...
journal_title:Acta clinica Belgica
pub_type: 杂志文章
doi:10.1179/acb.2008.63.2.007
更新日期:2008-03-01 00:00:00
abstract:CASE:A 45-year-old man presented at the emergency department (ED) with stomach pain since eight days. The patient was not worried about his symptoms and requested only pain relief. The emergency physician requested a consult of the gastroenterologist. Clinical examination was unremarkable. However, 12-lead ECG and isch...
journal_title:Acta clinica Belgica
pub_type: 杂志文章
doi:10.1080/17843286.2018.1460019
更新日期:2018-12-01 00:00:00
abstract::We have studied the clinical characteristics of 126 insulin-treated diabetic patients, mainly type I subjects, who regularly performed during 18 months home glucose monitoring. The numbers of strips used each month was of 60 +/- 33 (mean +/- lSD). During the study period, HbA1C levels decreased from 8.6 +/- 2.1 to 7.0...
journal_title:Acta clinica Belgica
pub_type: 杂志文章
doi:10.1080/17843286.1993.11718324
更新日期:1993-01-01 00:00:00
abstract::Sepsis is characterized by disturbances in liver perfusion and alterations in intrahepatic cellular functions and interactions. This provokes structural and functional liver damage as well as hepatocellular activation that is believed to perpetuate the immuno-inflammatory response. Changes in hepatic perfusion during ...
journal_title:Acta clinica Belgica
pub_type: 杂志文章,评审
doi:
更新日期:1999-08-01 00:00:00
abstract:INTRODUCTION:In many health care systems, strategies are currently deployed to engage patients and other stakeholders in decisions affecting hospital services. In this paper, a model for stakeholder involvement is presented and evaluated in three Flemish hospitals. In the model, a stakeholder committee advises the hosp...
journal_title:Acta clinica Belgica
pub_type: 杂志文章
doi:10.1080/17843286.2016.1246681
更新日期:2017-02-01 00:00:00
abstract:OBJECTIVE:This cross-sectional study registered the prevalence of sedative drug use and withdrawal strategies in geriatric in-patients from 30 centres in nine European countries. METHODS:We conducted a survey among young geriatricians using a standardised questionnaire on sedative drug use for more than three weeks. T...
journal_title:Acta clinica Belgica
pub_type: 杂志文章,多中心研究
doi:10.1179/acb.2006.019
更新日期:2006-05-01 00:00:00
abstract::Diabetes is currently one of the leading causes of end-stage renal failure requiring renal replacement therapy in the Western World. About 15% to 20% of type 1 diabetic patients and 30% to 40% of type 2 diabetic patients will eventually develop end-stage renal failure. To prevent the development or progression of diab...
journal_title:Acta clinica Belgica
pub_type: 杂志文章,评审
doi:10.1179/acb.2007.043
更新日期:2007-09-01 00:00:00
abstract::The patient in this report was diagnosed simultaneously with primary biliary cirrhosis (PBC), spondyloarthritis, and generalized morphea and was started on infliximab therapy. In addition to an improvement in clinical symptoms with this therapy, an improvement was also observed in laboratory parameters such as cholest...
journal_title:Acta clinica Belgica
pub_type: 杂志文章
doi:10.1080/17843286.2017.1290567
更新日期:2017-10-01 00:00:00
abstract::A case of double neutrophilic population in a more or less symptomless patient is described. The diagnosis is made on one hand by the presence of 2 distinct neutrophil clusters on the PEROX display of the H* 1 hematological automate, on the other hand by cytochemical peroxidase staining which clearly confirms the exis...
journal_title:Acta clinica Belgica
pub_type: 杂志文章
doi:10.1080/17843286.1993.11718337
更新日期:1993-01-01 00:00:00
abstract::A patient with severe rheumatoid arthritis received d-penicillamine treatment for 16 months. She developed mild pruritus 6 months after d-penicillamine initiation, and severe pemphigus 10 months after d-penicillamine was changed to azathioprine. Subsequent methylprednisolone pulse therapy resulted in a transient clini...
journal_title:Acta clinica Belgica
pub_type: 杂志文章,评审
doi:10.1080/17843286.1990.11718059
更新日期:1990-01-01 00:00:00
abstract::Pancreatic nodules are frequently found incidentally and often pose a diagnostic and therapeutic challenge when surgery is considered. We present the case of a 66-year-old cirrhotic patient with a pancreatic nodule with signal intensity and contrast enhancement pattern suggestive for a non-functional neuroendocrine le...
journal_title:Acta clinica Belgica
pub_type: 杂志文章
doi:10.1080/17843286.2020.1762351
更新日期:2020-05-12 00:00:00
abstract::The diagnosis of infective endocarditis remains difficult. The complication rate is very high. Serious complications may occur and the overall mortality is still 20-25%. The sooner the treatment is started, the better the final result. Antibiotic therapy is essential but cardiac surgery is frequently necessary. Early ...
journal_title:Acta clinica Belgica
pub_type: 杂志文章,评审
doi:10.1179/acb.2008.085
更新日期:2008-11-01 00:00:00
abstract::Background Evidence of diagnostic accuracy for proposed definitions of nocturnal polyuria is currently unclear. Purpose Systematic review to determine population-based evidence of the diagnostic accuracy of proposed definitions of nocturnal polyuria based on data from frequency-volume charts. Methods Seventeen pre-spe...
journal_title:Acta clinica Belgica
pub_type: 杂志文章
doi:10.1080/17843286.2018.1427821
更新日期:2018-08-01 00:00:00
abstract:BACKGROUND:The number of adult patients with surgical repaired congenital heart defects increases continuously. We were interested to compare late outcome after partial and complete atrioventricular defect repair (pAVSD and cAVSD, respectively) and to determine the most important reason for re-intervention. METHODS:Al...
journal_title:Acta clinica Belgica
pub_type: 杂志文章
doi:
更新日期:2005-09-01 00:00:00
abstract::We describe a case of acquired hepatocerebral degeneration (AHD) presenting with confusion and worsening memory problems since her discharge from the gastroenterology units. Cases of AHD are rare and are frequently confused with hepatic encephalopathy and Wilson's disease. There are no proven pharmacological therapies...
journal_title:Acta clinica Belgica
pub_type: 杂志文章
doi:10.1179/2295333715Y.0000000027
更新日期:2015-10-01 00:00:00
abstract::Gestational diabetes (GDM) is a frequent medical condition during pregnancy. GDM is associated with an increased risk of complications for both the mother and the baby during pregnancy and birth. Women with GDM also have an increased risk of developing type 2 diabetes later in life. Two large randomised intervention t...
journal_title:Acta clinica Belgica
pub_type: 杂志文章,评审
doi:10.2143/ACB.67.4.2062669
更新日期:2012-07-01 00:00:00
abstract::Lipoprotein(a) has many similarities to low density lipoproteins but possesses a unique protein moiety called apolipoprotein(a). The plasma concentration of lipoprotein(a) is mainly under genetic control and most of diets and hypolipidemic drugs do not change its level. Only nicotinic acid and neomycin are able to red...
journal_title:Acta clinica Belgica
pub_type: 杂志文章,评审
doi:10.1080/17843286.1991.11718193
更新日期:1991-01-01 00:00:00
abstract::Coronary artery disease is frequently associated with disturbed blood lipids and with a deficient blood fibrinolytic capacity. In order to investigate a possible link between hypercholesterolemia and hypofibrinolysis, we have investigated the effect of simvastatin, a HMG-CoA reductase inhibitor, on blood lipids and fi...
journal_title:Acta clinica Belgica
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1080/17843286.1992.11718214
更新日期:1992-01-01 00:00:00
abstract::We performed a systematic survey of original papers published in The Lancet throughout the years 1945, 1946, 1970 and 1995. The Lancet was chosen due to a conservative layout through these years, and the year 1946 added to the analysis to ponder for any war-induced bias. The general layout and structure of the journal...
journal_title:Acta clinica Belgica
pub_type: 历史文章,杂志文章
doi:10.1179/acb.2004.011
更新日期:2004-03-01 00:00:00
abstract::Diabetes registries have documented that the lifetime risk of diabetes amounts to at least 10% in the western world. Moreover the prevalence of type 2 diabetes is increasing worldwide especially in developing countries. Furthermore there is a secular trend toward earlier clinical manifestation of both type 1 and type ...
journal_title:Acta clinica Belgica
pub_type: 杂志文章,评审
doi:10.1179/acb.2004.001
更新日期:2004-01-01 00:00:00
abstract:BACKGROUND:Turner syndrome (TS) is characterized by dysmorphism and body disproportion. TS women are also susceptible to a range of chronic disorders including arterial hypertension (AHT), osteoporosis, sensorineural hearing loss (SNHL), type 2 diabetes mellitus (DM2) and thyroid disease. The association between dysmor...
journal_title:Acta clinica Belgica
pub_type: 杂志文章
doi:10.1080/17843286.2019.1606761
更新日期:2020-08-01 00:00:00
abstract:OBJECTIVE:We previously validated uHear™ to screen for hearing loss in older patients with cancer without a known hearing loss, as part of a comprehensive geriatric assessment (CGA). In view of low specificity, we tested a new modified uHear™ scoring system as described by Handzel. METHODS:Patients, aged ≥70 years, we...
journal_title:Acta clinica Belgica
pub_type: 杂志文章
doi:10.1080/17843286.2017.1392070
更新日期:2018-04-01 00:00:00
abstract::The National Institute for Insurance of Disease and Disablement (RIZIV/INAMI) in Belgium reimburses the costs of long term oxygen therapy (LTOT) by concentrators since 1984 and by liquid oxygen since 1988 for specific categories of patients supervised by approved medical centers. Since then we prescribed these therapi...
journal_title:Acta clinica Belgica
pub_type: 杂志文章
doi:10.1080/17843286.1995.11718439
更新日期:1995-01-01 00:00:00