当前位置： SCI文献检索 > JOURNAL OF CARDIAC FAILURE期刊下所有文献 > Time Course of Electrical Remodeling of Native Conduction After Cardiac Resynchronization Therapy and Its Impact on Clinical Outcome.

Time Course of Electrical Remodeling of Native Conduction After Cardiac Resynchronization Therapy and Its Impact on Clinical Outcome.

Abstract：

BACKGROUND:Cardiac resynchronization therapy (CRT) induces structural and electrical remodeling (ER) in heart failure (HF) patients. Our aim was to assess time course of ER of native conduction and mechanical remodeling after CRT and impact of CRT-induced ER on clinical outcome. METHODS AND RESULTS:We prospectively included 62 patients (aged 66 ± 10 years). Echocardiographic and ECG parameters were measured at baseline and 1, 3, 6, 9, and 12 months after implantation. Biventricular pacing was temporary inhibited during each follow-up to record intrinsic ECG. ER was defined as a decrease in native pre-implantation QRS duration ≥10 ms. During follow-up HF hospitalizations, cardiovascular death and transplantation (combined end point) were recorded. There were significant changes in intrinsic ECG parameters during follow-up; the narrowing of QRS duration was already observed after 1 month (median 185 ms [interquartile range (IQR) 175-194] vs 180 ms [170-194]; P < .001). Left ventricular (LV) volumes decreased only after 3 months of CRT (median end-systolic volume 167 mL [137-206] vs 140 mL [112-196]; P < .001). Only patients with ER (n = 24) exhibited significant mechanical remodeling and showed superior survival free from the combined end point compared with patients without ER (log-rank P = .028). CONCLUSIONS:Electrical remodeling of native conduction precedes detectable left ventricular structural changes after CRT. ER of native conduction is associated with better clinical outcome following CRT.

journal_name

J Card Fail

journal_title

Journal of cardiac failure

authors

Cvijić M,Žižek D,Antolič B,Zupan I

doi

10.1016/j.cardfail.2016.10.014

subject

Has Abstract

pub_date

2017-03-01 00:00:00

pages

257-261

issue

3

eissn

1071-9164

issn

1532-8414

pii

S1071-9164(16)31206-4

journal_volume

23

pub_type

杂志文章

相关文献

JOURNAL OF CARDIAC FAILURE文献大全
  • Patient-reported economic burden and the health status of heart failure patients.

    abstract：BACKGROUND:Heart failure (HF) guidelines recommend treatment with multiple medications to improve survival, functioning, and quality of life. Yet, HF treatments can be costly, resulting in significant economic burden for some patients. To date, there are few data on the impact of patients' perceived difficulties in aff...

    journal_title：Journal of cardiac failure

    pub_type： 杂志文章

    doi：10.1016/j.cardfail.2006.03.004

    authors： Conard MW,Heidenreich P,Rumsfeld JS,Weintraub WS,Spertus J,Cardiovascular Outcomes Research Consortium.

    更新日期：2006-06-01 00:00:00

  • The impact of heart failure on the classification of COPD severity.

    abstract：BACKGROUND:Pulmonary restriction-a reduction of lung volumes-is common in heart failure (HF), rendering severity grading of chronic obstructive pulmonary disease (COPD) potentially problematic in subjects with both diseases. We compared pulmonary function in patients with either HF or COPD, or the combination to assess...

    journal_title：Journal of cardiac failure

    pub_type： 杂志文章

    doi：10.1016/j.cardfail.2012.05.008

    authors： Güder G,Rutten FH,Brenner S,Angermann CE,Berliner D,Ertl G,Jany B,Lammers JW,Hoes AW,Störk S

    更新日期：2012-08-01 00:00:00

  • Tissue kallikrein and kinin infusion rescues failing myocardium after myocardial infarction.

    abstract：BACKGROUND:Tissue kallikrein is a serine proteinase that generates the vasoactive kinin peptide, which produces vasodilatory, angiogenic, and antiapoptotic effects. In this study, we investigated the effect of a stable supply of kallikrein and kinin on ventricular remodeling and blood vessel growth in rats after myocar...

    journal_title：Journal of cardiac failure

    pub_type： 杂志文章

    doi：10.1016/j.cardfail.2007.04.009

    authors： Yao YY,Yin H,Shen B,Chao L,Chao J

    更新日期：2007-09-01 00:00:00

  • Validation of a risk score for dying within 1 year of an admission for heart failure.

    abstract：BACKGROUND:Development of heart failure greatly reduces life expectancy. Accurate estimates of the risk of dying are needed in clinical practice and for risk adjustment in observational studies. A relatively simple risk score has been developed to determine the risk of dying within 1-year of an admission for heart fail...

    journal_title：Journal of cardiac failure

    pub_type： 杂志文章

    doi：10.1016/j.cardfail.2006.02.004

    authors： Rector TS,Ringwala SN,Ringwala SN,Anand IS

    更新日期：2006-05-01 00:00:00

  • Simultaneous right atrioventricular pacing: a novel model to study atrial remodeling and fibrillation in the setting of heart failure.

    abstract：BACKGROUND:Atrial fibrillation (AF) is a common arrhythmia which contributes to morbidity and mortality in patients with heart failure (HF). Atrial remodeling is a key substrate for the development of AF in HF. However, experimental models that study AF in the setting of HF have important limitations. We evaluated a ne...

    journal_title：Journal of cardiac failure

    pub_type： 杂志文章

    doi：10.1016/j.cardfail.2007.10.021

    authors： Laurent G,Moe GW,Hu X,Pui-Sze So P,Ramadeen A,Leong-Poi H,Doumanovskaia L,Konig A,Trogadis J,Courtman D,Strauss BH,Dorian P

    更新日期：2008-04-01 00:00:00

  • Carvedilol improves left atrial and left ventricular function and reserve in dilated cardiomyopathy after 1 year of treatment.

    abstract：BACKGROUND:The aim of this study was to evaluate the effects of carvedilol therapy on left atrial (LA) function in patients with heart failure from nonischemic dilated cardiomyopathy. METHODS AND RESULTS:Thirty-five patients (42.4 +/- 13.5 years) in New York Heart Association functional Class II-III have been studied....

    journal_title：Journal of cardiac failure

    pub_type： 杂志文章

    doi：10.1016/j.cardfail.2006.10.011

    authors： Paraskevaidis I,Farmakis D,Parissis JT,Dodouras T,Filippatos G,Tsiapras D,Kremastinos DT

    更新日期：2007-03-01 00:00:00

  • Fibrosis and Fibrotic Gene Expression in Pediatric and Adult Patients With Idiopathic Dilated Cardiomyopathy.

    abstract：BACKGROUND:Although fibrosis seems to be prognostic for adverse outcomes in adults with idiopathic dilated cardiomyopathy (IDC), little is known about the prevalence and development of fibrosis in pediatric IDC hearts. We hypothesized that there is less activation of fibrosis at a molecular level in pediatric IDC heart...

    journal_title：Journal of cardiac failure

    pub_type： 杂志文章

    doi：10.1016/j.cardfail.2016.11.006

    authors： Woulfe KC,Siomos AK,Nguyen H,SooHoo M,Galambos C,Stauffer BL,Sucharov C,Miyamoto S

    更新日期：2017-04-01 00:00:00

  • Racial differences in treatment-seeking delays among heart failure patients.

    abstract：BACKGROUND:Treatment-seeking delays for heart failure (HF) symptoms are significantly high. However, earlier studies did not closely examine race as a characteristic that could potentially influence delay times. The purpose of this study was (1) to describe racial differences in treatment-seeking delays for HF symptoms...

    journal_title：Journal of cardiac failure

    pub_type： 杂志文章

    doi：10.1054/jcaf.2002.129234

    authors： Evangelista LS,Dracup K,Doering LV

    更新日期：2002-12-01 00:00:00

  • Peripheral Intravenous Volume Analysis (PIVA) for Quantitating Volume Overload in Patients Hospitalized With Acute Decompensated Heart Failure-A Pilot Study.

    abstract：BACKGROUND:To determine the feasibility of peripheral intravenous volume analysis (PIVA) of venous waveforms for assessing volume overload in patients admitted to the hospital with acute decompensated heart failure (ADHF). METHODS:Venous waveforms were captured from a peripheral intravenous catheter in subjects admitt...

    journal_title：Journal of cardiac failure

    pub_type： 杂志文章

    doi：10.1016/j.cardfail.2018.05.003

    authors： Miles M,Alvis BD,Hocking K,Baudenbacher F,Guth C,Lindenfeld J,Brophy C,Eagle S

    更新日期：2018-08-01 00:00:00

  • Sensitivity and Specificity of a Five-Minute Cognitive Screening Test in Patients With Heart Failure.

    abstract：BACKGROUND:Cognitive impairment occurs in up to 80% of patients with heart failure (HF). The National Institute for Neurological Disorders and Stroke (NINDS) and the Canadian Stroke Network (CSN) recommend a 5-minute cognitive screening protocol that has yet to be psychometrically evaluated in HF populations. The aim o...

    journal_title：Journal of cardiac failure

    pub_type： 杂志文章

    doi：10.1016/j.cardfail.2015.08.343

    authors： Cameron JD,Gallagher R,Pressler SJ,McLennan SN,Ski CF,Tofler G,Thompson DR

    更新日期：2016-02-01 00:00:00

  • Metoprolol in dilated cardiomyopathy: is it possible to identify factors predictive of improvement? The Heart Muscle Disease Study Group.

    abstract：BACKGROUND:Some controlled clinical trials showed a beneficial effect of beta-blockers on symptoms, exercise tolerance, and left ventricular function in dilated cardiomyopathy. The purpose of this study was to investigate if there are clinical variables at baseline that could predict a favorable response to long-term m...

    journal_title：Journal of cardiac failure

    pub_type： 杂志文章

    doi：10.1016/s1071-9164(96)80027-3

    authors： DiLenarda A,Gregori D,Sinagra G,Lardieri G,Perkan A,Pinamonti B,Salvatore L,Secoli G,Zecchin M,Camerini F

    更新日期：1996-06-01 00:00:00

  • Prolonged electrical muscle stimulation exercise improves strength, peak VO2, and exercise capacity in patients with stable chronic heart failure.

    abstract：BACKGROUND:Exercise training can help patients with chronic heart failure but may be limited in its applicability due to age and other comorbidities. This investigation evaluated training responses to prolonged electrical muscle stimulation (EMS) in patients with stable chronic heart failure. METHODS AND RESULTS:In a ...

    journal_title：Journal of cardiac failure

    pub_type： 杂志文章,随机对照试验

    doi：10.1016/j.cardfail.2008.11.005

    authors： Banerjee P,Caulfield B,Crowe L,Clark AL

    更新日期：2009-05-01 00:00:00

  • Cardiac myocyte remodeling in hypertrophy and progression to failure.

    abstract：:Contracting myocytes are highly variable in size and generally resemble elliptical cylinders in shape. Although their arrangement within the ventricular wall is rather complex, their length runs in a tangential manner, and their transverse axis runs transmurally. Consequently, it was proposed many years ago that chang...

    journal_title：Journal of cardiac failure

    pub_type： 杂志文章

    doi：10.1054/jcaf.2002.129280

    authors： Gerdes AM

    更新日期：2002-12-01 00:00:00

  • Selective microembolization of the circumflex coronary artery in an ovine model: Dilated, ischemic cardiomyopathy and left ventricular dysfunction.

    abstract：BACKGROUND:Ventricular remodeling often occurs after myocardial infarction, yet the natural history remains unpredictable because of the chronicity of the process and therapeutic interventions involved. We induced cardiac dysfunction in an ovine model via selective microembolization of the circumflex coronary artery (L...

    journal_title：Journal of cardiac failure

    pub_type： 杂志文章

    doi：10.1016/j.cardfail.2003.08.013

    authors： Monreal G,Gerhardt MA,Kambara A,Abrishamchian AR,Bauer JA,Goldstein AH

    更新日期：2004-04-01 00:00:00

  • Identification of Heart Failure Events in Medicare Claims: The Atherosclerosis Risk in Communities (ARIC) Study.

    abstract：BACKGROUND:We examined the accuracy of Medicare heart failure (HF) diagnostic codes in the identification of acute decompensated (ADHF and chronic stable (CSHF) HF. METHODS AND RESULTS:Hospitalizations were identified from medical discharge records for Atherosclerosis Risk in Communities (ARIC) study participants with...

    journal_title：Journal of cardiac failure

    pub_type： 杂志文章

    doi：10.1016/j.cardfail.2015.07.013

    authors： Kucharska-Newton AM,Heiss G,Ni H,Stearns SC,Puccinelli-Ortega N,Wruck LM,Chambless L

    更新日期：2016-01-01 00:00:00

  • Influence of Risk on Reduction of Readmission and Death by Disease Management Programs in Heart Failure.

    abstract：OBJECTIVE:Disease management programs (DMPs) may reduce short-term readmission or death after heart failure (HF) hospitalization. We sought to determine if targeting of DMP to the highest-risk patients could improve efficiency. METHODS AND RESULTS:Patients (n = 412) admitted with HF were randomized to usual care or an...

    journal_title：Journal of cardiac failure

    pub_type： 杂志文章,多中心研究,随机对照试验

    doi：10.1016/j.cardfail.2019.01.015

    authors： Huynh QL,Whitmore K,Negishi K,Marwick TH,ETHELRED Investigators.

    更新日期：2019-05-01 00:00:00

  • Biomarker-guided therapies in heart failure: a forum for unified strategies.

    abstract：:The complexity of standard medical treatment for heart failure is growing, and such therapy typically involves 5 or more different medications. Given these pressures, there is increasing interest in harnessing cardiovascular biomarkers for clinical application to more effectively guide diagnosis, risk stratification, ...

    journal_title：Journal of cardiac failure

    pub_type：

    doi：10.1016/j.cardfail.2013.05.012

    authors： Fiuzat M,O'Connor CM,Gueyffier F,Mascette AM,Geller NL,Mebazaa A,Voors AA,Adams KF,Piña IL,Neyses L,Muntendam P,Felker GM,Pitt B,Zannad F,Bristow MR

    更新日期：2013-08-01 00:00:00

  • Variability in the clinical status of patients with advanced heart failure.

    abstract：BACKGROUND:The importance of repeated clinical assessments of patients with heart failure is widely accepted. The frequency of such follow-up is not established and is likely to depend on the natural history and variability of patients' health status and the availability and use of appropriate treatments. METHODS AND ...

    journal_title：Journal of cardiac failure

    pub_type： 杂志文章,多中心研究

    doi：10.1016/j.cardfail.2003.12.008

    authors： Hauptman PJ,Masoudi FA,Weintraub WS,Pina I,Jones PG,Spertus JA,Cardiovascular Outcomes Research Consortium.

    更新日期：2004-10-01 00:00:00

  • Implementation of a Multidisciplinary Inpatient Cardiology Service to Improve Heart Failure Outcomes in Guyana.

    abstract：BACKGROUND:Guyana is a small developing country with a high burden of cardiovascular disease and extensive barriers to optimal care delivery. We investigated the effectiveness of a newly established multidisciplinary inpatient cardiology service in this setting. METHODS:We performed an interrupted time-series cohort s...

    journal_title：Journal of cardiac failure

    pub_type： 杂志文章

    doi：10.1016/j.cardfail.2018.07.002

    authors： Klassen SL,Miller RJH,Hao R,Warnica JW,Fine NM,Carpen M,Isaac DL

    更新日期：2018-12-01 00:00:00

  • Design of an acute dP/dt hemodynamic measurement protocol to isolate cardiac effect of pacing.

    abstract：BACKGROUND:Invasively measured maximum increase in left ventricular pressure (LV dP/dtmax) has been used to assess biventricular (BiV) pacing. We quantified extracardiac factors contributing to its variability, and developed a protocol to minimize these effects in an acute pacing experiment. METHODS AND RESULTS:Contin...

    journal_title：Journal of cardiac failure

    pub_type： 杂志文章

    doi：10.1016/j.cardfail.2014.01.020

    authors： Thibault B,Dubuc M,Karst E,Andrade J,Dyrda K,Guerra PG,Macle L,Rivard L,Roy D,Talajic M,Ryu K,Farazi TG,Varma N,Khairy P

    更新日期：2014-05-01 00:00:00

  • Negative clinical outcomes associated with drug-related problems in heart failure (HF) outpatients: impact of a pharmacist in a multidisciplinary HF clinic.

    abstract：BACKGROUND:Drug-related negative outcomes (DNOs) are health problems that patients experience due to drug use or nonuse. Heart failure (HF) patients are at high risk of experiencing DNOs owing to polypharmacy, comorbidities, and age. METHODS AND RESULTS:Ninety-seven consecutive HF patients were enrolled and followed f...

    journal_title：Journal of cardiac failure

    pub_type： 杂志文章

    doi：10.1016/j.cardfail.2010.10.009

    authors： Gastelurrutia P,Benrimoj SI,Espejo J,Tuneu L,Mangues MA,Bayes-Genis A

    更新日期：2011-03-01 00:00:00

  • Cardiorenal interactions in acute decompensated heart failure: contemporary concepts facing emerging controversies.

    abstract：:Simultaneous dysfunction of the heart and the kidney represents a distinct spectrum of disease states composed of complex clinical scenarios with adverse outcomes. Worsening renal function (WRF) in the setting of acute decompensated heart failure (ADHF) is one such clinical setup for which the underlying mechanisms ar...

    journal_title：Journal of cardiac failure

    pub_type： 杂志文章,评审

    doi：10.1016/j.cardfail.2014.09.005

    authors： Kazory A,Elkayam U

    更新日期：2014-12-01 00:00:00

  • Quality assurance and cardiopulmonary exercise testing in clinical trials.

    abstract：BACKGROUND:Peak oxygen uptake (VO2) measured during cardiopulmonary exercise testing (CPX) is often used as an outcome measure in clinical trials. The purposes of this study are (a) to report the outcomes of a quality assurance (QA) procedure instituted in multisite clinical trials by a CPX data core laboratory and (b)...

    journal_title：Journal of cardiac failure

    pub_type： 杂志文章

    doi：10.1016/j.cardfail.2008.01.001

    authors： Brawner CA,Ehrman JK,Aldred H,Schairer JR,Keteyian SJ

    更新日期：2008-05-01 00:00:00

  • Risk Prediction Models for Incident Heart Failure: A Systematic Review of Methodology and Model Performance.

    abstract：BACKGROUND:Numerous models predicting the risk of incident heart failure (HF) have been developed; however, evidence of their methodological rigor and reporting remains unclear. This study critically appraises the methods underpinning incident HF risk prediction models. METHODS AND RESULTS:EMBASE and PubMed were searc...

    journal_title：Journal of cardiac failure

    pub_type： 杂志文章,评审

    doi：10.1016/j.cardfail.2017.03.005

    authors： Sahle BW,Owen AJ,Chin KL,Reid CM

    更新日期：2017-09-01 00:00:00

  • Assessment of left ventricular systolic function by the chest x-ray: comparison with radionuclide ventriculography.

    abstract：BACKGROUND:The value of the plain chest roentgenogram in predicting cardiac status remains controversial. METHODS AND RESULTS:A total of 111 randomly selected survivors of acute myocardial infarction (age 38 to 83 years) were studied prospectively. X-ray and radionuclide examinations were performed on a morning in the...

    journal_title：Journal of cardiac failure

    pub_type： 杂志文章

    doi：10.1016/j.cardfail.2004.10.004

    authors： Høilund-Carlsen PF,Gadsbøll N,Hein E,Stage P,Badsberg JH,Jensen BH

    更新日期：2005-05-01 00:00:00

  • Relevance of water gymnastics in rehabilitation programs in patients with chronic heart failure or coronary artery disease with normal left ventricular function.

    abstract：BACKGROUND:Exercise training is included in cardiac rehabilitation programs to enhance physical capacity and cardiovascular function. Among the existing rehabilitation programs, exercises in water are increasingly prescribed. However, it has been questioned whether exercises in water are safe and relevant in patients w...

    journal_title：Journal of cardiac failure

    pub_type： 杂志文章,随机对照试验

    doi：10.1016/j.cardfail.2011.04.008

    authors： Teffaha D,Mourot L,Vernochet P,Ounissi F,Regnard J,Monpère C,Dugué B

    更新日期：2011-08-01 00:00:00

  • Characteristics of patients who die with heart failure and a low ejection fraction in the new millennium.

    abstract：BACKGROUND:Therapies for heart failure (HF) with a low ejection fraction (EF) have delayed disease progression and prolonged survival, but the implications of these therapies on the end stages of HF have not been examined. METHODS AND RESULTS:Patients seen by the Brigham and Women's cardiomyopathy service with an EF <...

    journal_title：Journal of cardiac failure

    pub_type： 杂志文章

    doi：10.1016/j.cardfail.2005.08.001

    authors： Teuteberg JJ,Lewis EF,Nohria A,Tsang SW,Fang JC,Givertz MM,Jarcho JA,Mudge GH,Baughman KL,Stevenson LW

    更新日期：2006-02-01 00:00:00

  • Prognostic impact of combined late gadolinium enhancement on cardiovascular magnetic resonance and peak oxygen consumption in ambulatory patients with nonischemic dilated cardiomyopathy.

    abstract：BACKGROUND:Peak oxygen consumption (peak VO₂) and late gadolinium enhancement (LGE) on cardiovascular magnetic resonance (CMR) are prognostic in heart failure. We investigated whether LGE-CMR and peak VO₂combined had additive value in risk stratifying patients with nonischemic dilated cardiomyopathy (DCM). METHODS AND...

    journal_title：Journal of cardiac failure

    pub_type： 杂志文章

    doi：10.1016/j.cardfail.2014.08.005

    authors： Yamada T,Hirashiki A,Okumura T,Adachi S,Shimazu S,Shimizu S,Morimoto R,Takeshita K,Naganawa S,Kondo T,Murohara T

    更新日期：2014-11-01 00:00:00

  • Incident Heart Failure and Cognitive Decline: The Atherosclerosis Risk in Communities Study.

    abstract：BACKGROUND:Cognitive impairment is found in a significant proportion of patients with heart failure (HF). Although cognitive impairment may be a consequence of HF, early signs of cognitive impairment may also indicate subclinical vascular disease, and thus a risk factor for future cardiovascular events. METHODS AND RE...

    journal_title：Journal of cardiac failure

    pub_type： 杂志文章,多中心研究

    doi：10.1016/j.cardfail.2016.11.002

    authors： Bressler J,Knopman DS,Sharrett AR,Gottesman RF,Penman A,Chang PP,Rosamond WD,Boerwinkle E,Mosley TH

    更新日期：2017-01-01 00:00:00

  • Impact of 6 months of therapy with carvedilol on muscle sympathetic nerve activity in heart failure patients.

    abstract：BACKGROUND:The long-term effects of carvedilol on muscle sympathetic nerve activity (MSNA) and muscle blood flow at rest and exercise in patients with chronic heart failure (CHF) remain unknown. METHODS AND RESULTS:Twenty-six patients (New York Heart Association class II-III) were randomized to carvedilol or placebo. ...

    journal_title：Journal of cardiac failure

    pub_type： 临床试验,杂志文章,随机对照试验

    doi：10.1016/j.cardfail.2004.03.006

    authors： De Matos LD,Gardenghi G,Rondon MU,Soufen HN,Tirone AP,Barretto AC,Brum PC,Middlekauff HR,Negrão CE

    更新日期：2004-12-01 00:00:00