Liquid/solid extraction on diatomaceous earth for drug analysis in postmortem blood.

Abstract:

:Absorption extraction on diatomaceous earth was examined and found to be compatible with typical postmortem blood specimens encountered in forensic toxicology. The effects of solvent, solvent volume, eluate flow rate, and pH on drug recovery and extract quality were investigated. It was concluded that the best method was not necessarily that with the highest recoveries, but that considerations of extract quality were also required. The optimized method was compared with a single-step liquid/liquid extraction method and found to be superior in terms of ease of operation, extract quality, and absolute recovery. The results indicated also that although useful for screening, quantitative methods using liquid/solid extraction may be prone to error.

journal_name

J Forensic Sci

authors

Logan BK,Stafford DT

subject

Has Abstract

pub_date

1989-05-01 00:00:00

pages

553-64

issue

3

eissn

0022-1198

issn

1556-4029

journal_volume

34

pub_type

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