Childhood trauma, PTSD, and psychosis: Findings from a highly traumatized, minority sample.

Abstract:

:Trauma, especially early life trauma, is a risk factor for the development of both posttraumatic stress disorder and psychosis. The goal of the present study was to determine specific associations between exposure to childhood abuse, PTSD symptoms, and current psychotic disorder. Subjects were recruited from a public, urban hospital (N=328, >90% African American). Psychotic disorders were measured using the MINI International Neuropsychiatric Interview, PTSD was measured using the Clinician Administered PTSD Scale, child abuse was measured with the Childhood Trauma Questionnaire, and lifetime trauma exposure was measured with the Traumatic Events Inventory. Logistic regression analyses showed that both child abuse and current PTSD were statistically significant predictors of psychotic disorder beyond the effects of lifetime trauma load. When PTSD symptom clusters were examined, avoidance and numbing symptoms showed unique association with psychotic disorder independent of demographic variables and trauma exposure. Using bootstrapping techniques, we found a full indirect effect of PTSD on the association between child abuse and, suggesting a particularly important role of PTSD symptoms in relation to psychotic disorder in the presence of early life trauma. Because this is a cross-sectional study, continued research is needed to determine causality of such models. Identifying co-occurring psychosis and PTSD, particularly in populations with high levels of trauma exposure, is critical and will likely aid in more successful treatment interventions.

journal_name

Child Abuse Negl

journal_title

Child abuse & neglect

authors

Powers A,Fani N,Cross D,Ressler KJ,Bradley B

doi

10.1016/j.chiabu.2016.06.015

subject

Has Abstract

pub_date

2016-08-01 00:00:00

pages

111-8

eissn

0145-2134

issn

1873-7757

pii

S0145-2134(16)30112-0

journal_volume

58

pub_type

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