Abstract:
:Abhay Sharma brings two arguments in favor of transgenerational epigenetic inheritance (TGEI) in mammals when criticizing our work. He uses probability calculations and finds that the probability of obtaining the number of common changes in the in utero-exposed prospermatogonia and the same cells in the next generation is significant in our study. He also compares our results to other published datasets and concludes that the probability for the observed overlap between independent studies is significant. We disagree with both arguments of Sharma and show here that his meta-analysis and statistical calculations are not correct.
journal_name
Genome Bioljournal_title
Genome biologyauthors
Szabó PEdoi
10.1186/s13059-016-0978-0subject
Has Abstractpub_date
2016-05-16 00:00:00pages
105eissn
1474-7596issn
1474-760Xpii
10.1186/s13059-016-0978-0journal_volume
17pub_type
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