Abstract:
INTRODUCTION:Single- and multiple-fraction external beam radiotherapy (SFX-EBRT and MFX-EBRT) are palliative treatment options for localized metastatic bone pain. MFX is the preferred choice in many developed countries. Evidence shows little difference in how effectively SFX and MFX reduce pain. However, SFX is associated with higher retreatment and (in one meta-analysis) pathological fracture rates. MFX is, however, more time-consuming and expensive. We estimated the cost-effectiveness of SFX versus MFX for metastatic bone pain in breast, prostate and lung cancer in New Zealand. METHODS:We constructed a Markov microsimulation model to estimate health gain (in quality-adjusted life-years or QALYs), health system costs (in real 2011 NZ dollars) and cost-effectiveness. The model was populated using effect estimates from randomized controlled trials and other studies, and New Zealand cancer and cost data. Disability weights from the 2010 Global Burden of Disease study were used in estimating QALYs. RESULTS:Across all three cancers, QALY gains were similar for SFX compared to MFX, and per patient costs were less for SFX than MFX, with a difference of NZ$1469 (95% uncertainty interval $1112 to $1886) for lung cancer, $1316 ($810 to $1854) for prostate cancer and $1344 ($855 to $1846) for breast cancer. Accordingly, from a cost-effectiveness perspective, SFX was the preferable treatment option. Various sensitivity analyses did not overturn the clear preference for SFX. CONCLUSION:For all three cancers, SFX was clearly more cost-effective than MFX. This adds to the case for desisting from offering MFX to patients with metastatic bone pain, from a cost-effectiveness angle.
journal_name
J Med Imaging Radiat Oncoljournal_title
Journal of medical imaging and radiation oncologyauthors
Collinson L,Kvizhinadze G,Nair N,McLeod M,Blakely Tdoi
10.1111/1754-9485.12467subject
Has Abstractpub_date
2016-10-01 00:00:00pages
650-660issue
5eissn
1754-9477issn
1754-9485journal_volume
60pub_type
杂志文章abstract:INTRODUCTION:The aim of this study was to assess the association between intrasinus gas and dural venous sinus thrombosis (DVST) in patients with blunt head trauma. METHODS:One hundred and two consecutive patients with blunt head trauma imaged with non-enhanced CT and CT head venography at our institution between 1 Ju...
journal_title:Journal of medical imaging and radiation oncology
pub_type: 杂志文章
doi:10.1111/1754-9485.12865
更新日期:2019-06-01 00:00:00
abstract:INTRODUCTION:Tumour response in lung cancer treatment is monitored by measuring lesion size in computed tomography (CT). Spectral CT (SCT) offers additional information on tumour tissue besides morphology. We evaluated SCT iodine content (IC) and performed spectral slope analysis to assess the response of non-small-cel...
journal_title:Journal of medical imaging and radiation oncology
pub_type: 杂志文章
doi:10.1111/1754-9485.12926
更新日期:2019-10-01 00:00:00
abstract:INTRODUCTION:We investigated the endorectal balloon (ERB) as a method to improve post-prostatectomy clinical target volume (CTV) stability. METHODS:Seventy cone-beam CT (CBCT) obtained during radiotherapy treatment from seven patients treated with an ERB and 68 CBCT from seven patients treated without an ERB were cont...
journal_title:Journal of medical imaging and radiation oncology
pub_type: 杂志文章
doi:10.1111/1754-9485.12300
更新日期:2015-08-01 00:00:00
abstract:INTRODUCTION:Computed tomography colonography (CTC) for the detection of colorectal disease is gaining popularity as an alternative to colonoscopy. This has been associated with an increase in incidental extra-colonic findings such as abdominal aortic aneurysms. However, due to the patient selection process of obtainin...
journal_title:Journal of medical imaging and radiation oncology
pub_type: 杂志文章
doi:10.1111/1754-9485.12535
更新日期:2017-04-01 00:00:00
abstract::Summary The aim of this study was to assess the impact of F-18 fluorodeoxyglucose-positron emission tomography (FDG-PET) CT on radiotherapy planning parameters for patients treated curatively with radiotherapy for non-small-cell lung cancer (NSCLC). Five patients with stages I-III NSCLC underwent a diagnostic FDG-PET ...
journal_title:Journal of medical imaging and radiation oncology
pub_type: 杂志文章
doi:10.1111/j.1754-9485.2010.02155.x
更新日期:2010-04-01 00:00:00
abstract::Giant cerebral aneurysms are associated with a poor prognosis, with 2-year survival rates reported as low as 20% (Sundt et al.; Syman et al.). Morbidity is largely associated with haemorrhage, local compressive effects and thrombosis. While endovascular coiling has been acknowledged as a safe treatment in small to med...
journal_title:Journal of medical imaging and radiation oncology
pub_type: 杂志文章
doi:10.1111/1754-9485.12267
更新日期:2015-02-01 00:00:00
abstract::Congenital extrahepatic portocaval shunt is a rare condition that is described mostly in female patients. We report an unusual case of a young adult male patient with type 1 congenital extrahepatic portocaval shunt with associated development of a focal nodular hyperplasia on a background of regenerative nodules. With...
journal_title:Journal of medical imaging and radiation oncology
pub_type: 杂志文章
doi:10.1111/j.1754-9485.2011.02303.x
更新日期:2011-10-01 00:00:00
abstract::We present the results of a pilot study designed to investigate methods that may be applied to develop a patient position correction protocol for the post-prostatectomy patient receiving radiotherapy. Imaging was carried out with cone beam CT (CBCT) to investigate its suitability for detecting changes in rectal and bl...
journal_title:Journal of medical imaging and radiation oncology
pub_type: 杂志文章
doi:10.1111/j.1754-9485.2009.02057.x
更新日期:2009-04-01 00:00:00
abstract:INTRODUCTION:Clinical data supporting the use of hypofractionated whole breast radiotherapy (HF-WBRT) in early-stage breast cancer patients have accumulated over the last decade. Despite the availability of the published evidence, the adoption rate of HF-WBRT has been slower-than-expected. We sought to assess the tempo...
journal_title:Journal of medical imaging and radiation oncology
pub_type: 杂志文章
doi:10.1111/1754-9485.12897
更新日期:2019-08-01 00:00:00
abstract:INTRODUCTION:Marker clips are commonly deployed at the site of a percutaneous breast biopsy. Studies have shown that displacement of the clip from the site of deployment is not uncommon. The objective of this study was to determine how much 'migration' could be seen with fixed structures within the breast tissue across...
journal_title:Journal of medical imaging and radiation oncology
pub_type: 杂志文章
doi:10.1111/1754-9485.12327
更新日期:2015-10-01 00:00:00
abstract::The aims of this study were to investigate whether intrafraction prostate motion can affect the accuracy of online prostate positioning using implanted fiducial markers and to determine the effect of prostate rotations on the accuracy of the software-predicted set-up correction shifts. Eleven patients were treated wit...
journal_title:Journal of medical imaging and radiation oncology
pub_type: 杂志文章
doi:10.1111/j.1440-1673.2008.02006.x
更新日期:2008-10-01 00:00:00
abstract:INTRODUCTION:The aim of this study is to compare the results of positron emission tomography (PET)/CT with bremsstrahlung imaging following Y-90 radiation synovectomy. METHODS:All patients referred to our institution for Y-90 radiation synovectomy between July 2011 and February 2012 underwent both PET/CT and bremsstra...
journal_title:Journal of medical imaging and radiation oncology
pub_type: 杂志文章
doi:10.1111/1754-9485.12049
更新日期:2013-10-01 00:00:00
abstract::To describe the chest CT features reported in children with confirmed COVID-19 infection, published in English literature. A systematic review was completed on PubMed, Embase and Scopus databases on the 1st of June 2020 using the PICO strategy. The NIH Quality Assessment Tool was used to assess the quality of the sele...
journal_title:Journal of medical imaging and radiation oncology
pub_type: 杂志文章
doi:10.1111/1754-9485.13098
更新日期:2020-10-01 00:00:00
abstract::The retroperitoneal space is made up of multiple communicating compartments. Here we detail an unusual case of ectopic gas almost exclusively isolated to the properitoneal space, a space in communication with the retroperitoneum. This case is a reminder that when extraperitoneal gas is identified, the retroperitoneal ...
journal_title:Journal of medical imaging and radiation oncology
pub_type: 杂志文章
doi:10.1111/1754-9485.12820
更新日期:2019-02-01 00:00:00
abstract::This case report details a clinical trial's first recruited liver cancer patient who underwent a course of stereotactic body radiation therapy treatment utilising audiovisual biofeedback breathing guidance. Breathing motion results for both abdominal wall motion and tumour motion are included. Patient 1 demonstrated i...
journal_title:Journal of medical imaging and radiation oncology
pub_type: 临床试验,杂志文章
doi:10.1111/1754-9485.12343
更新日期:2015-10-01 00:00:00
abstract::Erectile dysfunction (ED) commonly affects the quality of life of men after treatment of prostate cancer. We conducted a placebo-controlled, crossover randomised trial to assess the efficacy and tolerability of sildenafil citrate in the treatment of ED developing after external beam radiation treatment (EBRT) of local...
journal_title:Journal of medical imaging and radiation oncology
pub_type: 杂志文章,随机对照试验
doi:10.1111/j.1754-9485.2010.02168.x
更新日期:2010-06-01 00:00:00
abstract:INTRODUCTION:Paragangliomas are commonly treated with surgery, while radiotherapy is reserved for those that are inoperable or have relapsed. However, this retrospective study aims to determine whether radiotherapy is a viable initial treatment for paragangliomas. METHODS:Of 73 tumours researched, 44 were diagnosed an...
journal_title:Journal of medical imaging and radiation oncology
pub_type: 临床试验,杂志文章
doi:10.1111/1754-9485.12226
更新日期:2015-04-01 00:00:00
abstract::The use of Positron emission tomography/computerised tomography (PET/CT) is well established in the staging and assessment of treatment response of lymphoma. Recent studies have suggested that whole body diffusion-weighted imaging -magnetic resonance imaging (WB-DW-MRI) may be an alternative to PET/CT in both staging ...
journal_title:Journal of medical imaging and radiation oncology
pub_type: 杂志文章,评审
doi:10.1111/1754-9485.12723
更新日期:2018-03-25 00:00:00
abstract:INTRODUCTION:The goal of this initial clinical study was to test a new positron emission/tomography imager and biopsy system (PEM/PET) in a small group of selected subjects to assess its clinical imaging capabilities. Specifically, the main task of this study is to determine whether the new system can successfully be u...
journal_title:Journal of medical imaging and radiation oncology
pub_type: 杂志文章
doi:10.1111/j.1754-9485.2010.02230.x
更新日期:2011-02-01 00:00:00
abstract:INTRODUCTION:To investigate anatomical response-related changes in the head and neck region during a course of radical radiotherapy and their impact on the planned dosimetry. METHODS:The study consisted of 10 patients with primary mucosal carcinoma. Patients' nutritional requirements were managed as per departmental p...
journal_title:Journal of medical imaging and radiation oncology
pub_type: 杂志文章
doi:10.1111/j.1754-9485.2010.02209.x
更新日期:2010-10-01 00:00:00
abstract:INTRODUCTION:The aims of this study were to determine the diagnostic value of MR urography and to compare the T2- and T1-weighted MR urography techniques in patients with urinary diversion. METHODS:We retrospectively reviewed 19 MR urograms in 14 patients (13 male and one female, 8-77 years old, mean age: 54.2) with u...
journal_title:Journal of medical imaging and radiation oncology
pub_type: 杂志文章
doi:10.1111/j.1754-9485.2011.02318.x
更新日期:2011-12-01 00:00:00
abstract::Advances in interventional radiology have seen the adaptation of urological endoscopic laser techniques to treat biliary tract calculi. Percutaneous transhepatic biliary laser lithotripsy provides an effective alternative procedure for the management of intrahepatic or conventionally refractory choledocholithiasis whi...
journal_title:Journal of medical imaging and radiation oncology
pub_type: 杂志文章
doi:10.1111/1754-9485.12952
更新日期:2019-12-01 00:00:00
abstract::The aim of this study was to evaluate the prognostic value of metabolic tumour volume (MTV) and total lesion glycolysis (TLG) for small cell lung cancer (SCLC). MEDLINE, EMBASE and Cochrane Library databases were systematically searched. The pooled hazard ratio (HR) was used to measure the influence of MTV and TLG on ...
journal_title:Journal of medical imaging and radiation oncology
pub_type: 杂志文章,meta分析
doi:10.1111/1754-9485.12805
更新日期:2019-02-01 00:00:00
abstract:INTRODUCTION:Pulmonary embolism (PE) is the third most common cause of death from cardiovascular disease. Computed-tomographic pulmonary angiography (CTPA) is an accurate and safe test for diagnosing PE. The aim of this retrospective analysis was to evaluate the effects on image quality (IQ) of electrocardiogram (ECG) ...
journal_title:Journal of medical imaging and radiation oncology
pub_type: 杂志文章,随机对照试验
doi:10.1111/1754-9485.12147
更新日期:2014-01-01 00:00:00
abstract:INTRODUCTION:A unified and logical system of descriptors for diagnostic imaging examinations and procedures is a desirable resource for radiology in Australia and New Zealand and is needed to support core activities of RANZCR. Existing descriptor systems available in Australia and New Zealand (including the Medicare DI...
journal_title:Journal of medical imaging and radiation oncology
pub_type: 杂志文章
doi:10.1111/1754-9485.12191
更新日期:2014-08-01 00:00:00
abstract:BACKGROUND:Respiratory-gated radiotherapy (RGRT) is used in several centres around the world. However, there is continuing controversy regarding the benefit of this technique. The aims of this study are to quantify the dosimetric benefits and the potential predictive factors. METHODS:Thirty-four consecutive patients w...
journal_title:Journal of medical imaging and radiation oncology
pub_type: 临床试验,杂志文章
doi:10.1111/1754-9485.12088
更新日期:2013-12-01 00:00:00
abstract::Deep Inspiration Breath-Hold (DIBH) techniques for breast cancer radiation therapy (RT) have reduced cardiac dose compared to Free Breathing (FB). Recently, a voluntary deep inspiration breath-hold (vDIBH) technique was established using in-room lasers and skin tattoos to monitor breath-hold. An in-house quality asses...
journal_title:Journal of medical imaging and radiation oncology
pub_type: 杂志文章
doi:10.1111/1754-9485.12616
更新日期:2017-10-01 00:00:00
abstract:INTRODUCTION:We aimed to investigate the impact of radiation treatment in early-stage triple negative breast cancer (TNBC). METHODS:Patients with early stage (T1-3, N0-2, M0) TNBC were identified using the New Zealand breast cancer register. The outcomes of local recurrence (LRFR), local recurrence free survival (LRFS...
journal_title:Journal of medical imaging and radiation oncology
pub_type: 杂志文章
doi:10.1111/1754-9485.12933
更新日期:2019-10-01 00:00:00
abstract::The aim of this study was to evaluate our experience with the retrievable Cook Celect inferior vena cava (IVC) filter (William Cook, Europe) with regard to insertion, efficiency, ease of retrieval, and any associated complications. A retrospective review was performed of 115 patients (41 female, 74 male, mean age 47.9...
journal_title:Journal of medical imaging and radiation oncology
pub_type: 杂志文章
doi:10.1111/j.1754-9485.2009.02039.x
更新日期:2009-02-01 00:00:00
abstract:INTRODUCTION:Since its onset in the spring of 2009, the H1N1 pandemic has kept health-care professionals busy worldwide. Even though it often causes respiratory tract illness, reports describing the radiological manifestations in infected children are few. The purpose of this study was twofold: to review the chest radi...
journal_title:Journal of medical imaging and radiation oncology
pub_type: 杂志文章
doi:10.1111/j.1754-9485.2011.02264.x
更新日期:2011-06-01 00:00:00