The myogenic electric organ of Sternopygus macrurus: a non-contractile tissue with a skeletal muscle transcriptome.

Abstract:

:In most electric fish species, the electric organ (EO) derives from striated muscle cells that suppress many muscle properties. In the gymnotiform Sternopygus macrurus, mature electrocytes, the current-producing cells of the EO, do not contain sarcomeres, yet they continue to make some cytoskeletal and sarcomeric proteins and the muscle transcription factors (MTFs) that induce their expression. In order to more comprehensively examine the transcriptional regulation of genes associated with the formation and maintenance of the contractile sarcomere complex, results from expression analysis using qRT-PCR were informed by deep RNA sequencing of transcriptomes and miRNA compositions of muscle and EO tissues from adult S. macrurus. Our data show that: (1) components associated with the homeostasis of the sarcomere and sarcomere-sarcolemma linkage were transcribed in EO at levels similar to those in muscle; (2) MTF families associated with activation of the skeletal muscle program were not differentially expressed between these tissues; and (3) a set of microRNAs that are implicated in regulation of the muscle phenotype are enriched in EO. These data support the development of a unique and highly specialized non-contractile electrogenic cell that emerges from a striated phenotype and further differentiates with little modification in its transcript composition. This comprehensive analysis of parallel mRNA and miRNA profiles is not only a foundation for functional studies aimed at identifying mechanisms underlying the transcription-independent myogenic program in S. macrurus EO, but also has important implications to many vertebrate cell types that independently activate or suppress specific features of the skeletal muscle program.

journal_name

PeerJ

journal_title

PeerJ

authors

Pinch M,Güth R,Samanta MP,Chaidez A,Unguez GA

doi

10.7717/peerj.1828

subject

Has Abstract

pub_date

2016-04-14 00:00:00

pages

e1828

issn

2167-8359

pii

1828

journal_volume

4

pub_type

杂志文章

相关文献

PeerJ文献大全
  • Climatic niche comparison across a cryptic species complex.

    abstract::According to current molecular evidence, the Chionaspis pinifoliae heterophyllae species complex has been recognized as 10 cryptic species. In this study, we construct potential distribution maps for seven cryptic species based on climatic variables. This was done to assess the main environmental factors that have con...

    journal_title:PeerJ

    pub_type: 杂志文章

    doi:10.7717/peerj.7042

    authors: Zhao Q,Zhang H,Wei J

    更新日期:2019-05-31 00:00:00

  • Blood markers of endothelial dysfunction and their correlation to cerebrovascular reactivity in patients with chronic hepatitis C infection.

    abstract::Although liver cirrhosis and hepatocellular carcinoma are major consequences of hepatitis C (HCV), there has been an increasing number of studies examining extrahepatic manifestations, especially those caused by systemic chronic inflammation and metabolic complications that might predispose HCV patients to atheroscler...

    journal_title:PeerJ

    pub_type: 杂志文章

    doi:10.7717/peerj.10723

    authors: Pavicic Ivelja M,Dolic K,Tandara L,Perkovic N,Mestrovic A,Ivic I

    更新日期:2021-01-14 00:00:00

  • Evidence for low prevalence of ranaviruses in Ontario, Canada's freshwater turtle population.

    abstract:Background:Ontario, Canada is home to eight native species of turtles; all eight are federally listed as Species At Risk, due to anthropogenic threats. However, until recently, reports of infectious disease have been lacking. Ranavirus is seen as an emerging threat for ectotherms globally, with mass die-offs most often...

    journal_title:PeerJ

    pub_type: 杂志文章

    doi:10.7717/peerj.6987

    authors: Carstairs SJ

    更新日期:2019-05-20 00:00:00

  • Exploring perceptions of meaningfulness in visual representations of bivariate relationships.

    abstract::Researchers often need to consider the practical significance of a relationship. For example, interpreting the magnitude of an effect size or establishing bounds in equivalence testing requires knowledge of the meaningfulness of a relationship. However, there has been little research exploring the degree of relationsh...

    journal_title:PeerJ

    pub_type: 杂志文章

    doi:10.7717/peerj.6853

    authors: Beribisky N,Davidson H,Cribbie RA

    更新日期:2019-05-14 00:00:00

  • Comments and corrections on 3D modeling studies of locomotor muscle moment arms in archosaurs.

    abstract::In a number of recent studies we used computer modeling to investigate the evolution of muscle leverage (moment arms) and function in extant and extinct archosaur lineages (crocodilians, dinosaurs including birds and pterosaurs). These studies sought to quantify the level of disparity and convergence in muscle moment ...

    journal_title:PeerJ

    pub_type: 杂志文章

    doi:10.7717/peerj.1272

    authors: Bates K,Maidment SC,Schachner ER,Barrett PM

    更新日期:2015-10-08 00:00:00

  • Numerical ability and improvement through interindividual cooperation varied between two cyprinid fish species, qingbo and crucian carp.

    abstract::We used qingbo (Spinibarbus sinensis) and Chinese crucian carp (Carassius auratus) to test whether numerical discrimination could be improved by the coexistence and possible cooperation of conspecies or heterospecies. We conducted a spontaneous shoal choice test of singletons, conspecific dyads and heterospecific dyad...

    journal_title:PeerJ

    pub_type: 杂志文章

    doi:10.7717/peerj.6619

    authors: Xiong W,Yi LC,Tang ZH,Fu SJ

    更新日期:2019-03-11 00:00:00

  • The sensitivity of biological finite element models to the resolution of surface geometry: a case study of crocodilian crania.

    abstract::The reliability of finite element analysis (FEA) in biomechanical investigations depends upon understanding the influence of model assumptions. In producing finite element models, surface mesh resolution is influenced by the resolution of input geometry, and influences the resolution of the ensuing solid mesh used for...

    journal_title:PeerJ

    pub_type: 杂志文章

    doi:10.7717/peerj.988

    authors: McCurry MR,Evans AR,McHenry CR

    更新日期:2015-06-02 00:00:00

  • Avian community structure and habitat use of Polylepis forests along an elevation gradient.

    abstract:BACKGROUND:As one of the highest forest ecosystems in the world, Polylepis forests are recognized both as center of endemism and diversity along the Andes and as an ecosystem under serious threat from habitat loss, fragmentation, and climate change due to human activities. Effective conservation efforts are limited, in...

    journal_title:PeerJ

    pub_type: 杂志文章

    doi:10.7717/peerj.3220

    authors: Sevillano-Ríos CS,Rodewald AD

    更新日期:2017-04-27 00:00:00

  • Patterns of triclosan resistance in Vibrionaceae.

    abstract::The antimicrobial additive triclosan has been used in personal care products widely across the globe for decades. Triclosan resistance has been noted among Vibrio spp., but reports have been anecdotal and the extent of phenotypic triclosan resistance across the Vibrionaceae family has not been established. Here, tricl...

    journal_title:PeerJ

    pub_type: 杂志文章

    doi:10.7717/peerj.5170

    authors: Lydon KA,Robertson MJ,Lipp EK

    更新日期:2018-07-12 00:00:00

  • Physical activity and pre-diabetes-an unacknowledged mid-life crisis: findings from NHANES 2003-2006.

    abstract::The prevalence of pre-diabetes (PD) among US adults has increased substantially over the past two decades. By current estimates, over 34% of US adults fall in the PD category, 84% of whom meet the American Diabetes Association's criteria for impaired fasting glucose (IFG). Low physical activity (PA) and/or sedentary b...

    journal_title:PeerJ

    pub_type: 杂志文章

    doi:10.7717/peerj.499

    authors: Farni K,Shoham DA,Cao G,Luke AH,Layden J,Cooper RS,Dugas LR

    更新日期:2014-08-19 00:00:00

  • A near-infrared spectroscopy routine for unambiguous identification of cryptic ant species.

    abstract::Species identification-of importance for most biological disciplines-is not always straightforward as cryptic species hamper traditional identification. Fibre-optic near-infrared spectroscopy (NIRS) is a rapid and inexpensive method of use in various applications, including the identification of species. Despite its e...

    journal_title:PeerJ

    pub_type: 杂志文章

    doi:10.7717/peerj.991

    authors: Kinzner MC,Wagner HC,Peskoller A,Moder K,Dowell FE,Arthofer W,Schlick-Steiner BC,Steiner FM

    更新日期:2015-09-15 00:00:00

  • Characterization of retinal regeneration in adult zebrafish following multiple rounds of phototoxic lesion.

    abstract::Müller glia in the zebrafish retina respond to retinal damage by re-entering the cell cycle, which generates large numbers of retinal progenitors that ultimately replace the lost neurons. In this study we compared the regenerative outcomes of adult zebrafish exposed to one round of phototoxic treatment with adult zebr...

    journal_title:PeerJ

    pub_type: 杂志文章

    doi:10.7717/peerj.5646

    authors: Ranski AH,Kramer AC,Morgan GW,Perez JL,Thummel R

    更新日期:2018-09-20 00:00:00

  • Aberrant expression of two miRNAs promotes proliferation, hepatitis B virus amplification, migration and invasion of hepatocellular carcinoma cells: evidence from bioinformatic analysis and experimental validation.

    abstract:Background:As key negative regulators of gene expression, microRNAs (miRNAs) play an important role in the onset and progression of hepatocellular carcinoma (HCC). This study aimed to identify the miRNAs involved in HCC carcinogenesis and their regulated genes. Methods:The Gene Expression Omnibus (GEO) dataset (GSE108...

    journal_title:PeerJ

    pub_type: 杂志文章

    doi:10.7717/peerj.9100

    authors: Liu Y,Cao Y,Cai W,Wu L,Zhao P,Liu XG

    更新日期:2020-04-29 00:00:00

  • Evaluation of the estimate bias magnitude of the Rao's quadratic diversity index.

    abstract::Rao's quadratic diversity index is one of the most widely applied diversity indices in functional and phylogenetic ecology. The standard way of computing Rao's quadratic diversity index for an ecological assemblage with a group of species with varying abundances is to sum the functional or phylogenetic distances betwe...

    journal_title:PeerJ

    pub_type: 杂志文章

    doi:10.7717/peerj.5211

    authors: Chen Y,Wu Y,Shen TJ

    更新日期:2018-07-06 00:00:00

  • The R2R3-MYB transcription factor family in Taxus chinensis: identification, characterization, expression profiling and posttranscriptional regulation analysis.

    abstract::The MYB transcription factor family is one of the largest gene families playing regulatory roles in plant growth and development. The MYB family has been studied in a variety of plant species but has not been reported in Taxus chinensis. Here we identified 72 putative R2R3-MYB genes in T. chinensis using a comprehensi...

    journal_title:PeerJ

    pub_type: 杂志文章

    doi:10.7717/peerj.8473

    authors: Hu X,Zhang L,Wilson I,Shao F,Qiu D

    更新日期:2020-02-17 00:00:00

  • Morphological traits: predictable responses to macrohabitats across a 300 km scale.

    abstract::Species traits may provide a short-cut to predicting generalities in species turnover in response to environmental change, particularly for poorly known taxa. We ask if morphological traits of assemblages respond predictably to macrohabitats across a large scale. Ant assemblages were collected at nine paired pasture a...

    journal_title:PeerJ

    pub_type: 杂志文章

    doi:10.7717/peerj.271

    authors: Yates ML,Andrew NR,Binns M,Gibb H

    更新日期:2014-03-04 00:00:00

  • A "modified Obel" method for the severity scoring of (endocrinopathic) equine laminitis.

    abstract:Background:Laminitis is a common equine disease characterized by foot pain, and is commonly diagnosed using a five-grade Obel system developed in 1948 using sepsis-related cases. However, endocrinopathic laminitis is now the most common form of the disease and clinical signs may be mild, or spread across two Obel grade...

    journal_title:PeerJ

    pub_type: 杂志文章

    doi:10.7717/peerj.7084

    authors: Meier A,de Laat M,Pollitt C,Walsh D,McGree J,Reiche DB,von Salis-Soglio M,Wells-Smith L,Mengeler U,Mesa Salas D,Droegemueller S,Sillence MN

    更新日期:2019-06-07 00:00:00

  • Effects of graded concentrations of supplemental lead on lead concentrations in tissues of pigs and prediction equations for estimating dietary lead intake.

    abstract::The objectives of this experiment were to determine the effects of graded dietary lead (Pb) concentrations on body weight and Pb concentrations in blood, hair, soft tissues, and urine from pigs and to generate equations for estimating daily Pb intake. Sixteen barrows with initial body weight 36.3 kg (standard deviatio...

    journal_title:PeerJ

    pub_type: 杂志文章

    doi:10.7717/peerj.3936

    authors: Reddy KE,Park KR,Lee SD,Yoo JH,Son AR,Lee HJ

    更新日期:2017-11-01 00:00:00

  • Element concentrations in pelagic Sargassum along the Mexican Caribbean coast in 2018-2019.

    abstract::The massive influx of pelagic Sargassum spp. (sargasso) into the Mexican Caribbean Sea has caused major deterioration of the coastal environment and has affected the tourism industry as well as livelihoods since 2015. Species of Sargassum have high capacity to absorb metals; thus, leachates of sargasso may contribute ...

    journal_title:PeerJ

    pub_type: 杂志文章

    doi:10.7717/peerj.8667

    authors: Rodríguez-Martínez RE,Roy PD,Torrescano-Valle N,Cabanillas-Terán N,Carrillo-Domínguez S,Collado-Vides L,García-Sánchez M,van Tussenbroek BI

    更新日期:2020-02-26 00:00:00

  • Impact of intercropping on the coupling between soil microbial community structure, activity, and nutrient-use efficiencies.

    abstract::Sugarcane-soybean intercropping has been widely used to control disease and improve nutrition in the field. However, the response of the soil microbial community diversity and structure to intercropping is not well understood. Since microbial diversity corresponds to soil quality and plant health, a pot experiment was...

    journal_title:PeerJ

    pub_type: 杂志文章

    doi:10.7717/peerj.6412

    authors: Lian T,Mu Y,Jin J,Ma Q,Cheng Y,Cai Z,Nian H

    更新日期:2019-02-08 00:00:00

  • Development of guidelines for tertiary education institutions to assist them in supporting students with a mental illness: a Delphi consensus study with Australian professionals and consumers.

    abstract::Background. The age at which most young people are in tertiary education is also the age of peak onset for mental illness. Because mental health problems can have adverse effects on students' academic performance and welfare, institutions require guidance how they can best provide support. However, the scientific evid...

    journal_title:PeerJ

    pub_type: 杂志文章

    doi:10.7717/peerj.43

    authors: Reavley NJ,Ross AM,Killackey E,Jorm AF

    更新日期:2013-02-26 00:00:00

  • Hypothyroidism and diabetes mellitus - a risky dual gestational endocrinopathy.

    abstract::Objectives. Diabetes mellitus (DM) and hypothyroidism are each associated with increased rate of pregnancy complications. However, their combined morbidity during gestation is poorly studied. Therefore, the aims of this study were to determine the prevalence of the combined morbidity of DM & hypothyroidism and whether...

    journal_title:PeerJ

    pub_type: 杂志文章

    doi:10.7717/peerj.52

    authors: Tirosh D,Benshalom-Tirosh N,Novack L,Press F,Beer-Weisel R,Wiznitzer A,Mazor M,Erez O

    更新日期:2013-03-19 00:00:00

  • Bibliographic revision of Mesacanthion Filipjev, 1927 (Nematoda: Thoracostomopsidae) with description of a new species from Jeju Island, South Korea.

    abstract::A new species of the genus Mesacanthion Filipjev, 1927 was discovered during a survey of natural beaches of Jeju Island in South Korea. The new species Mesacanthion jejuensissp. nov. shares general morphology of the genus such as the outer labial and cephalic setae being situated at the middle of cephalic capsule, wel...

    journal_title:PeerJ

    pub_type: 杂志文章

    doi:10.7717/peerj.8023

    authors: Jeong R,Tchesunov AV,Lee W

    更新日期:2019-11-18 00:00:00

  • Sponge exhalent seawater contains a unique chemical profile of dissolved organic matter.

    abstract::Sponges are efficient filter feeders, removing significant portions of particulate and dissolved organic matter (POM, DOM) from the water column. While the assimilation and respiration of POM and DOM by sponges and their abundant microbial symbiont communities have received much attention, there is virtually no inform...

    journal_title:PeerJ

    pub_type: 杂志文章

    doi:10.7717/peerj.2870

    authors: Fiore CL,Freeman CJ,Kujawinski EB

    更新日期:2017-01-11 00:00:00

  • A late surviving Pliocene seal from high latitudes of the North Atlantic realm: the latest monachine seal on the southern margin of the North Sea.

    abstract:Background:The family of true seals, the Phocidae, is subdivided into two subfamilies: the southern Monachinae, and the northern Phocinae, following the subfamilies' current distribution: extant Monachinae are largely restricted to the (sub-)Antarctic and the eastern Pacific, with historical distributions of the monk s...

    journal_title:PeerJ

    pub_type: 杂志文章

    doi:10.7717/peerj.5734

    authors: Dewaele L,Lambert O,Louwye S

    更新日期:2018-10-09 00:00:00

  • Associations of ADL and IADL disability with physical and mental dimensions of quality of life in people aged 75 years and older.

    abstract:Background:Quality of life is an important health outcome for older persons. It predicts the adverse outcomes of institutionalization and premature death. The aim of this cross-sectional study was to determine the influence of both disability in activities of daily living (ADL) and instrumental activities of daily livi...

    journal_title:PeerJ

    pub_type: 杂志文章

    doi:10.7717/peerj.5425

    authors: Gobbens RJ

    更新日期:2018-08-09 00:00:00

  • Tensiomyographical responsiveness to peripheral fatigue in quadriceps femoris.

    abstract:Background:Fatigue influences athletic performance and can also increase the risk of injury in sports, and most of the methods to evaluate it require an additional voluntary effort. Tensiomyography (TMG), which uses electrical stimulation and a displacement sensor to evaluate muscle contraction properties of one or mor...

    journal_title:PeerJ

    pub_type: 杂志文章

    doi:10.7717/peerj.8674

    authors: Martín-San Agustín R,Medina-Mirapeix F,Casaña-Granell J,García-Vidal JA,Lillo-Navarro C,Benítez-Martínez JC

    更新日期:2020-02-28 00:00:00

  • Nuclear microsatellites reveal population genetic structuring and fine-scale pattern of hybridization in the Japanese mantis shrimp Oratosquilla oratoria.

    abstract::The interplay between historical and contemporary processes can produce complex patterns of genetic differentiation in the marine realm. Recent mitochondrial and nuclear sequence analyses revealed cryptic speciation in the Japanese mantis shrimp Oratosquilla oratoria. Herein, we applied nuclear microsatellite markers ...

    journal_title:PeerJ

    pub_type: 杂志文章

    doi:10.7717/peerj.10270

    authors: Cheng J,Zhang N,Sha Z

    更新日期:2020-11-05 00:00:00

  • Arbutin increases Caenorhabditis elegans longevity and stress resistance.

    abstract::Arbutin (p-hydroxyphenyl-β-D-glucopyranoside), a well-known tyrosinase inhibitor, has been widely used as a cosmetic whitening agent. Although its natural role is to scavenge free radicals within cells, it has also exhibited useful activities for the treatment of diuresis, bacterial infections and cancer, as well as a...

    journal_title:PeerJ

    pub_type: 杂志文章

    doi:10.7717/peerj.4170

    authors: Zhou L,Fu X,Jiang L,Wang L,Bai S,Jiao Y,Xing S,Li W,Ma J

    更新日期:2017-12-20 00:00:00

  • Distribution, habitat suitability, conservation state and natural history of endangered salamander Bolitoglossa pandi.

    abstract:Background:Pandi's mushroom-tongue salamander (Bolitoglossa pandi) is one of the threatened amphibians in South America, as well as a flagship species for the Colombian conservation agenda. This species is endemic to the Andean cloud forests of the western slope of the Cordillera Oriental of Colombia, occurring only in...

    journal_title:PeerJ

    pub_type: 杂志文章

    doi:10.7717/peerj.9901

    authors: Angarita-Sierra T,Bonilla-Gómez MA,Sánchez DA,Acosta-Galvis AR,Medina-Ovalle H,Solano-Moreno A,Ulloa-Rengifo S,Guevara-Guevara D,Torres-Ramirez JJ,Curaca-Fierro S,Cabrera-Amaya DM,Infante-Betancour JA,Londoño-Montaño LF,Albarán

    更新日期:2020-09-24 00:00:00