Abstract：
:Both ethylene and propylene glycol alkyl ethers (EGAEs and PGAEs, respectively) are widely used, mainly as solvents, in industrial and household products. Some EGAEs demonstrate gonadotoxic, embriotoxic, fetotoxic and teratogenic effects in both humans and experimental animals. Due to the noxious impact of these ethers on reproduction and development of organisms EGAEs are replaced for considerably less toxic PGAEs. The data on the mechanisms of testicular, embriotoxic, fetotoxic and teratogenic effects of EGAEs are presented in this paper. Our particular attention was focused on the metabolism of some EGAEs and their organ-specific toxicities, apoptosis of spermatocytes associated with changes in the expression of various genes that code for oxidative stress factors, protein kinases and nuclear hormone receptors. :Etery alkilowe glikolu etylenowego (ethylene glycol alkyl ethers – EGAE) i propylenowego (propylene glycol alkyl ethers – PGAE) są szeroko stosowane w przemyśle i gospodarstwie domowym, głównie jako rozpuszczalniki. Niektóre EGAE wykazują działanie gonadotoksyczne, embriotoksyczne, fetotoksyczne i teratogenne zarówno u ludzi, jak i zwierząt doświadczalnych. Ze względu na szkodliwe działanie tych eterów na rozrodczość i rozwój organizmu EGAE są zastępowane znacznie mniej toksycznymi PGAE. W niniejszej pracy przedstawiono dane na temat mechanizmów toksycznego działania EGAE na komórki rozrodcze, zarodek i płód. Szczególną uwagę zwrócono na metabolizm niektórych EGAEs i ich toksyczność narządową, a także na apoptozę spermatocytów związaną ze zmianami ekspresji genów, które kodują czynniki stresu oksydacyjnego, kinazy białkowe i jądrowe receptory hormonów. Med. Pr. 2015;66(5):725–737.
journal_name
Med Prjournal_title
Medycyna pracyauthors
Starek-Świechowicz B,Starek Adoi
10.13075/mp.5893.00219subject
Has Abstractpub_date
2015-01-01 00:00:00pages
725-37issue
5eissn
0465-5893issn
2353-1339pii
59135journal_volume
66pub_type
杂志文章,评审相关文献
MEDYCYNA PRACY文献大全abstract：:Work performed in a sitting position, despite the fact that it does not require a lot of physical effort, can be the cause of many musculoskeletal disorders (MSD), especially when performed for a long time and in the wrong position. Musculoskeletal disorders are currently a common problem in the working population. Th...
journal_title：Medycyna pracy
pub_type： 杂志文章,评审
doi：10.13075/mp.5893.00810
更新日期：2019-07-16 00:00:00
abstract：:The study aimed at detecting psychological effects of chronic occupational exposure to the mixtures of solvents used in furniture varnishing. 36 exposed workers and 34 controls selected so as to account for age, education level and the nature work were examined. The following tests were used in the examinations: the N...
journal_title：Medycyna pracy
pub_type： 杂志文章
doi：
更新日期：1992-01-01 00:00:00
abstract：:Oral glucose test and serum insulin determination was performed in 192 workers of a large metallurgical factory. The subjects were divided into four groups: 1. exposed to isolated noise, 2. exposed to local vibration, 3. exposed to the whole body vibration, and 4. control group. In the group exposed to the whole body ...
journal_title：Medycyna pracy
pub_type： 杂志文章
doi：
更新日期：1993-01-01 00:00:00
abstract：BACKGROUND:Toxicity of organophosphate insecticides is mainly due to the inhibition of acetylcholinesterase (AChE). However organophosphate insecticides in acute as well as in chronic and subchronic intoxication may lead to oxidative stress causing enhancement of lipid peroxidation and changing the activities of antiox...
journal_title：Medycyna pracy
pub_type： 杂志文章
doi：
更新日期：2011-01-01 00:00:00
abstract：:A gas chromatographic method for determination of extraction naphtha and benzene has been developed. The best parameters of chromatographic separation were found. Under those conditions it is possible to estimate the total concentration of all ingredients of extraction naphtha as one peak clearly separated from benzen...
journal_title：Medycyna pracy
pub_type： 杂志文章
doi：
更新日期：1980-01-01 00:00:00
abstract：:Mixtures of organic solvents are used extensively in industry. The aim of this study was to develop a method for the determination of components of commercial multi-component solvent mixtures, and to perform qualitative and quantitative analyses of the mixtures. Farbasol, Solvesso and Shellsol mixtures were analysed b...
journal_title：Medycyna pracy
pub_type： 杂志文章
doi：
更新日期：1995-01-01 00:00:00
abstract：:Noise is one of the most common physical risks in the workplace. Long term exposure to its high levels (above 80-85 dB) can pose a significant threat to health of workers, including hearing loss. Noise can also be a burdensome factor hampering work, causing stress and various health problems. In the European Union abo...
journal_title：Medycyna pracy
pub_type： 杂志文章
doi：
更新日期：2012-01-01 00:00:00
abstract：BACKGROUND:Carpal tunnel syndrome (CTS) is a musculoskeletal condition that often impairs the fitness to work. Our aim is to retrospectively evaluate the association between physical exposures in meat processing industry in Northern Italy and the CTS, taking into account non-occupational factors. MATERIAL AND METHODS:...
journal_title：Medycyna pracy
pub_type： 杂志文章
doi：10.13075/mp.5893.00605
更新日期：2017-03-24 00:00:00
abstract：BACKGROUND:This study is aimed at evaluating the awareness among hunters and foresters concerning the activities undertaken for the prevention of Borrelia burgdorferi infections. MATERIAL AND METHODS:The study group included 236 hunters from Poland and 339 foresters from Ukraine. The study was based on an origi...
journal_title：Medycyna pracy
pub_type： 杂志文章
doi：10.13075/mp.5893.00841
更新日期：2020-01-20 00:00:00
abstract：:Work in a fire-brigade is very often associated with exposure to traumatic events. Some firefighters manifest post-traumatic stress disorder (PTSD) symptoms. In spite of PTSD development, firefighters have to perform various tasks according to their responsibilities. The paper addresses the problem of the relationship...
journal_title：Medycyna pracy
pub_type： 杂志文章
doi：
更新日期：2001-01-01 00:00:00
abstract：BACKGROUND:This paper presents the prevalence of health promotion in workplaces in Poland. It characterises the undertaken ac tions, their rationale and perceived obstacles. It analyses the diversity of these phenomena in the companies of different financial soundness and level of employment. MATERIAL AND METHODS:The ...
journal_title：Medycyna pracy
pub_type： 杂志文章,随机对照试验
doi：10.13075/mp.5893.2013.0076
更新日期：2013-01-01 00:00:00
abstract：BACKGROUND:The aims of the survey was to analyze the musculoskeletal system load during work performed by nurse anesthetists and to identify activities involving poor work postures along with their causes. MATERIAL AND METHODS:The observation process and the Ovako Working Posture Analysing System (OWAS) method were us...
journal_title：Medycyna pracy
pub_type： 杂志文章
doi：
更新日期：2008-01-01 00:00:00
abstract：BACKGROUND:The work of nurses in hospitals is connected with shift and night work. Numerous publications suggest that shift work is responsible for some gastrointestinal disturbances (heartburn, dyspepsia, loss of appetite, stomach pain). It is not yet conclusive whether shift and night work is responsible for more fre...
journal_title：Medycyna pracy
pub_type： 杂志文章
doi：
更新日期：2006-01-01 00:00:00
abstract：:This paper discusses occupational exposure to chemical carcinogens in Poland in 2001 based on data obtained from the Central Register of Carcinogen Agents (CRCA). The data on 3017 enterprises, in which employees were exposed to chemical carcinogens (chemicals, mixtures and technological processes involving carcinogeni...
journal_title：Medycyna pracy
pub_type： 杂志文章
doi：
更新日期：2004-01-01 00:00:00
abstract：:The paper is aimed at analysing the correlation between zinc protoporphyrin and hemoglobin concentrations and lead level in blood and the correlation between hemoglobin concentration and zinc protoporphyrin content in erythrocytes. The studies covered 73 men aged 19-58, exposed for 1-15 years. The control group was co...
journal_title：Medycyna pracy
pub_type： 杂志文章
doi：
更新日期：1982-01-01 00:00:00
abstract：:Environmental tobacco smoke (ETS) exposure induces serious negative health consequences, of which the increased risk of cardiovascular diseases, cancer, respiratory symptoms and poor pregnancy outcomes appear to be most important. Taking into account those health consequences of ETS exposure most countries have introd...
journal_title：Medycyna pracy
pub_type： 杂志文章,评审
doi：
更新日期：2011-01-01 00:00:00
abstract：BACKGROUND:Studies conducted to assess aluminum (Al)-induced toxicity to humans and environment. It has been implicated that Al is involved in the etiology of Alzheimer's disease and other neurodegenerative disorders, though this is controversial. The aim of the present study was to assess Al effects on the nervous sys...
journal_title：Medycyna pracy
pub_type： 杂志文章
doi：
更新日期：2005-01-01 00:00:00
abstract：:700 persons i.e. 98.6% of the workers of the textile plant "Biruna" in Białystok, breathing in such synthetic fibres as acrylic yarn, anilane etc. were examined. The prevalence of chronic nonspecific bronchopulmonary diseases was found to be highly enhanced by smoking, whether in those exposed to dust or in those unex...
journal_title：Medycyna pracy
pub_type： 杂志文章
doi：
更新日期：1981-01-01 00:00:00
abstract：BACKGROUND:Excessive spinal load caused by a schoolbag has a major impact on the child's body posture. The National Sanitary Inspector recommends the limit of schoolbag weight as corresponding to 10-15% of the student's weight. The aim of the study was to assess the spinal load of children aged 6-9 years, caused by sch...
journal_title：Medycyna pracy
pub_type： 杂志文章
doi：10.13075/mp.5893.00998
更新日期：2020-12-03 00:00:00
abstract：:Long-term investigations of noise in coal mines enhanced the need to take measurements at work stations posing high risk of methane explosion. To facilitate evaluation of noise hazard at the workplace in coal mines, attempts have been made to apply TTS measurements. Measurements of TTS taken within 3 to 5 minutes afte...
journal_title：Medycyna pracy
pub_type： 杂志文章
doi：
更新日期：1983-01-01 00:00:00
abstract：:Perchloroethylene is used mainly as a solvent in dry cleaning, cleaning of electrical equipment, and degreasing of metal parts. The authors report a case of acute poisoning with perchloroethylene contracted by a maintenance worker when cleaning an electric transformer. Since perchloroethylene may cause severe poisonin...
journal_title：Medycyna pracy
pub_type： 杂志文章
doi：10.13075/mp.5893.00778
更新日期：2019-06-14 00:00:00
abstract：:The objective of the study was to determine the occurrence of a low-back-pain syndrome in coalminers. The pilot study also aimed at the evaluation of the study design and methods, prior to planned full-scale epidemiological assessment of the syndrome in this workforce. In two groups of subjects (204 persons employed i...
journal_title：Medycyna pracy
pub_type： 杂志文章
doi：
更新日期：1996-01-01 00:00:00
abstract：:The work addresses technical aspects of the assessment of exposure to electromagnetic fields (EMF) in the environment based on cellular telephony systems. In this paper, EMF parameters, important to the biosphere exposure, are discussed, and the methods for the EMF assessment: theoretical analysis of EMF intensity in ...
journal_title：Medycyna pracy
pub_type： 杂志文章,评审
doi：
更新日期：2010-01-01 00:00:00
abstract：:In order to spread in occupational medicine the simple screening test allowing to detect the alpha-1-antitrypsin deficiency, the conformability of four procedures with the method of radial immunodiffusion has been analysed. From the received data it results that for the preliminary diagnostics of deficiency in mass ex...
journal_title：Medycyna pracy
pub_type： 杂志文章
doi：
更新日期：1977-01-01 00:00:00
abstract：:The authors present the results of the study carried out in South Moravia, Czech Republic, in a group of 140 patients (76 women and 64 men) with occupational carpal tunnel syndrome (CTS). The time-lag between the occupational disease certification and the investigation ranged from 2 to 14 years. The mean age of person...
journal_title：Medycyna pracy
pub_type： 杂志文章
doi：
更新日期：2003-01-01 00:00:00
abstract：:The prevalence of diabetes and a significant proportion of unawareness of its risk among the patients indicate the need to include into general prophylactic examinations the standards of medical certification, which would prevent discrimination and ensure public safety. In certifying medical predispositions to work in...
journal_title：Medycyna pracy
pub_type： 杂志文章
doi：10.13075/mp.5893.2014.009
更新日期：2014-01-01 00:00:00
abstract：:Changes in the system of research planning and co-ordination in Poland promoted the development of centrally supervised programs with preferences in financial terms. Of 100 centrally supervised programs, four are related to medical sciences, in this one--to occupational health. The research program, accepted after a p...
journal_title：Medycyna pracy
pub_type： 杂志文章
doi：
更新日期：1987-01-01 00:00:00
abstract：BACKGROUND:The engagement of children in work is common in agricultural families. Work of children brings about cific benefits to both the family and the children; however, at the same time, it creates many hazards, including health risk. MATERIALS AND METHOD:The aim of the study was to determine current and delayed h...
journal_title：Medycyna pracy
pub_type： 杂志文章
doi：
更新日期：2013-01-01 00:00:00
abstract：:The case liver sarcoma in a 47 year-old male worker exposed to vinyl chloride during 22 years is presented. During that period the patient inhaled about 0.8105 kg of vinyl chloride. It is estimated that the asymptomatic phase of liver angiosarcoma lasted 21 years. The patient died 4 months after occurrence of clinical...
journal_title：Medycyna pracy
pub_type： 杂志文章
doi：
更新日期：1996-01-01 00:00:00
abstract：:The examinations of methemoglobin and properdine levels as well as of the function of peripheral blood leukocytes in the tetranitrozolic blue reduction test (NBT) were performed in the exposed persons. The obtained results were compared with those of the control group, using statistical methods. It has been found that...
journal_title：Medycyna pracy
pub_type： 杂志文章
doi：
更新日期：1977-01-01 00:00:00
